Lensless microscope

By designing lensless microscopes and using lensless microscopes to solve the problems of large size and high cost in existing microscopes, miniaturization and low-cost, lowering the threshold for medical research and testing, and providing faster and cheaper diagnosis and treatment in areas with limited resource conditions.

CN222618870UActive Publication Date: 2025-03-14宁波海兹恩科技有限公司
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Patent Information

Application Number
CN202421245167.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-03
Publication Date
2025-03-14
Estimated Expiration
2034-06-03

AI Technical Summary

Technical Problem

The existing microscopes are large in size and high in cost, making it difficult to meet the application fields of non-destructive, high-resolution, large field of view and intelligence.

Method used

A lensless microscope was designed, using a shell, cover, imaging chip, power supply module and lighting system structure, and miniaturization and low cost through lensless microscopy technology.

Benefits of technology

On the premise of ensuring imaging quality, the overall size of the microscope is smaller, lighter in weight, and greatly reduced the cost, which lowers the threshold for medical research and testing, and provides faster and cheaper diagnosis and treatment in areas with limited resource conditions.

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Abstract

The utility model provides a lensless microscope, relates to the technical field of microscopes, and aims to solve the technical problems of large size and high cost of a microscope in the prior art. A lensless microscope comprises a shell, a cover body, an imaging chip, a power supply module and an illumination system, a first installation cavity is formed in the shell, the first installation cavity forms a first opening in the upper end face of the shell, the imaging chip and the power supply module are both connected with the shell and located in the first installation cavity, and a liquid containing area is arranged on the upper end face of the imaging chip. A second mounting cavity is formed in the cover body, a second opening is formed in the second mounting cavity in the lower end face of the cover body, the lighting system is connected with the cover body and located in the second mounting cavity, the cover body is detachably connected to the upper end of the shell, and when the cover body is connected to the upper end of the shell, the first opening and the second opening are closed, and the lighting system is located over the liquid containing area. The imaging chip is electrically connected with the power supply module, and the cover body is connected with a control assembly used for controlling on-off of electric connection of the lighting system and the imaging chip.
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Description

Technical Field

[0001] The utility model relates to the technical field of microscopes, in particular to a lens-free microscope. Background Art

[0002] With the in-depth research on life science issues and the increasing demand for detection methods in laboratory medicine, optical microscopy technology has achieved rapid development. However, with the increase in microscope functions and the improvement in performance, the microscope system has become increasingly bulky, complex, difficult to maintain and expensive, which limits its further application in application fields with non-destructive, high-resolution, large field of view and intelligent requirements. Under the premise of ensuring the imaging quality of optical microscope equipment, smaller size, lower cost and simpler operation will drastically lower the threshold of medical research and testing, and provide faster and cheaper instant diagnosis and treatment for critically ill patients in resource-limited areas. Therefore, designing a microscope imaging device with small size, low cost and simple operation is an urgent problem to be solved. Utility Model Content

[0003] In view of the deficiencies of the prior art, the purpose of the utility model is to provide a lensless microscope to solve the technical problems of large size and high cost of microscopes in the prior art.

[0004] In order to solve the above technical problems, the utility model provides a lensless microscope, including a shell, a cover body, an imaging chip, a power supply module and a lighting system. A first installation cavity is provided in the shell body, and the first installation cavity forms a first opening on the upper end surface of the shell body. The imaging chip and the power supply module are both connected to the shell body and are located in the first installation cavity. A liquid placement area is provided on the upper end surface of the imaging chip. A second installation cavity is provided in the cover body, and the second installation cavity forms a second opening on the lower end surface of the cover body. The lighting system is connected to the cover body and is located in the second installation cavity. The cover body is detachably connected to the upper end of the shell. When the cover body is connected to the upper end of the shell, the first opening and the second opening are closed and the lighting system is located directly above the liquid placement area. The imaging chip is electrically connected to the power supply module, and a control component for controlling the electrical connection between the lighting system and the imaging chip is connected to the cover body.

[0005] After adopting the above structure, the lensless microscope of the utility model has the following advantages: when the cover body is separated from the shell, the liquid sample to be tested is placed into the liquid placement area from the first opening, and then the cover body is closed, the circuit is connected by the control component, and the imaging chip and the lighting system are powered by the power supply module. The light of the lighting system is irradiated through the first opening to the liquid sample to be tested in the liquid placement area, and the imaging chip integrating the image sensor chip technology and the intelligent image recognition technology images the liquid sample to be tested. The lensless microscopic imaging technology breaks through the limitation of the space-bandwidth product brought by the lens of the traditional optical microscope. Under the premise of ensuring the imaging quality of the optical microscope equipment, the overall volume of the microscope is smaller and the weight is lighter, and the cost is also greatly reduced.

[0006] As an improvement, the control component includes an upper contact and a lower contact, the upper contact is connected to the cover body and is located in the second installation cavity, the upper contact is electrically connected to the lighting system, the lower contact is connected to the shell and is located in the first installation cavity, the lower contact is electrically connected to the imaging chip, when the cover body is connected to the shell, the upper contact is in contact with the lower contact and is electrically connected, when the cover body is separated from the shell, the upper contact is separated from the lower contact; with this structure, opening the cover body indicates the separation of the upper contact and the lower contact, and the lighting system is powered off, and closing the cover body indicates the contact of the upper contact and the lower contact, and the lighting system is powered on and imaging is performed by the imaging chip, without the need to set up an additional switch or press the switch separately, which reduces costs and is more convenient to use.

[0007] As an improvement, a first base plate is provided in the second mounting cavity, the first base plate is connected to the inner wall of the cover body, a first annular convex portion is circumferentially provided on the outer peripheral wall of the upper part of the upper contact, a first through hole is provided on the first base plate, the upper contact is inserted into the first through hole, the bottom end of the first annular convex portion is abutted against the upper end surface of the first base plate, the bottom end of the upper contact is lower than the bottom end of the first base plate or is flush with the bottom end of the first base plate; adopting this structure, the upper contact is connected by setting the first base plate, which has the advantages of simple structure and convenient connection. The setting of the first annular convex portion can prevent the upper contact from falling out of the first through hole, thereby improving the stability of the connection between the upper contact and the first base plate.

[0008] As an improvement, the first opening is located directly above the liquid placement area, a second through hole is provided on the upper end face of the shell, a second annular protrusion is circumferentially provided on the outer peripheral wall of the lower part of the lower contact, the lower contact is inserted into the second through hole, and the upper end face of the lower contact is higher than the upper end face of the shell or flush with the upper end face of the shell; with this structure, the first opening is only provided directly above the liquid placement area, which can reduce the exposure of the structure in the first installation cavity and reduce the entry of impurities such as dust.

[0009] As an improvement, a first base plate is provided in the second installation cavity, the first base plate is connected to the inner wall of the cover body, a third through hole is provided on the first base plate, the lighting system is connected to the third through hole, and the light of the lighting system is irradiated downward through the third through hole. When the cover body is connected to the shell body, the third through hole is located directly above the liquid placement area. With this structure, the lighting system is connected by setting the first base plate, which has the advantages of simple structure and convenient connection.

[0010] As an improvement, the imaging chip includes a first chip and a second chip, the power supply module includes a first power supply and a second power supply, the first chip, the second chip, the first power supply and the second power supply are all connected to the shell and are located in the first installation cavity, the first chip is electrically connected to the first power supply, the second chip is electrically connected to the second power supply, the first chip and the second chip are electrically connected, the control component is used to control the on and off of the electrical connection between the lighting system and the first chip, and the liquid placement area is arranged on the upper end surface of the second chip; the first chip in the imaging chip is electrically connected to the lighting system, so that the first power supply can power the lighting system.

[0011] As an improvement, the bottom end of the first chip is connected to the bottom end of the shell through a plurality of first supporting columns, and the first chip is located above the first power supply. The bottom end of the second chip is connected to the bottom end of the shell through a plurality of second supporting columns, and the second chip is located above the second power supply. With this structure, the first chip and the second chip are respectively elevated by the first supporting columns and the second supporting columns, making the internal structure of the shell more compact and further reducing the overall volume of the microscope.

[0012] As an improvement, the shell includes an outer cover and a second base plate, the first installation cavity is arranged in the outer cover and forms a first opening on the upper end surface of the outer cover, the first installation cavity forms a third opening on the lower end surface of the outer cover, the second base plate is detachably connected to the inner wall of the outer cover, the first power supply, the second power supply, the first support column and the second support column are all connected to the second base plate; with this structure, the power supply module and the imaging chip and other structures are directly connected to the second base plate, and then the second base plate is connected to the outer cover, which makes installation more convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a schematic diagram of the exploded structure of the utility model.

[0014] Figure 2 It is a schematic diagram of the exploded structure of the cover body in the utility model.

[0015] Figure 3 It is a schematic diagram of the exploded structure of the shell part in the utility model.

[0016] Figure 4 It is a three-dimensional structural schematic diagram of the utility model.

[0017] Figure numerals: 1. shell; 101. outer cover; 102. second base plate; 2. cover body; 3. imaging chip; 31. first chip; 32. second chip; 4. power supply module; 41. first power supply; 42. second power supply; 5. lighting system; 6. first installation cavity; 7. first opening; 8. liquid placement area; 9. second installation cavity; 10. second opening; 11. control component; 111. upper contact; 112. lower contact; 12. first base plate; 13. first annular protrusion; 14. first through hole; 15. second through hole; 16. second annular protrusion; 17. third through hole; 18. first support column; 19. second support column; 20. third opening. DETAILED DESCRIPTION

[0018] The lensless microscope of the utility model is described in detail below in conjunction with the accompanying drawings.

[0019] like Figures 1 to 4 As shown, a lensless microscope includes a housing 1, a cover 2, an imaging chip 3, a power supply module 4 and an illumination system 5. Figure 3 As shown, a first installation cavity 6 is provided in the housing 1, and a first opening 7 is formed on the upper end surface of the housing 1. The imaging chip 3 and the power supply module 4 are both connected to the housing 1 and are located in the first installation cavity 6. A liquid placement area 8 is provided on the upper end surface of the imaging chip 3. When the cover 2 is not connected to the housing 1, the first opening 7 exposes the liquid placement area 8, and the liquid sample to be tested can be placed on the liquid placement area 8 from the first opening 7. Figure 2 As shown, a second installation cavity 9 is provided in the cover body 2, and the second installation cavity 9 forms a second opening 10 on the lower end surface of the cover body 2, the lighting system 5 is connected to the cover body 2 and is located in the second installation cavity 9, the cover body 2 is detachably connected to the upper end of the shell 1, and the specific connection method between the cover body 2 and the shell 1 is the existing technology and is not repeated here; when the cover body 2 is connected to the upper end of the shell 1, the first opening 7 and the second opening 10 are closed and the lighting system 5 is located directly above the liquid placement area 8, that is, at this time, the first opening 7 and the second opening 10 are interconnected and are both located inside the microscope, and the microscope at this time is a closed structure; the imaging chip 3 is electrically connected to the power supply module 4, and the cover body 2 is connected to a control component 11 for controlling the electrical connection between the lighting system 5 and the imaging chip 3.

[0020] like Figure 1As shown, the control component 11 includes an upper contact 111 and a lower contact 112. The upper contact 111 is connected to the cover body 2 and is located in the second installation cavity 9. The upper contact 111 is electrically connected to the lighting system 5. Specifically, a first bottom plate 12 is provided in the second installation cavity 9. The outer wall of the first bottom plate 12 is connected to the inner wall of the cover body 2. The first bottom plate 12 is fixed to the cover body 2 by bolts. A first annular protrusion 13 is circumferentially provided on the outer peripheral wall of the upper part of the upper contact 111. The upper end surface of the first annular protrusion 13 is flush with the upper end surface of the upper contact 111. The first bottom plate 12 is provided with a first through hole 14, the upper contact 111 is inserted into the first through hole 14, the bottom end of the first annular protrusion 13 is against the upper end surface of the first bottom plate 12, the bottom end of the upper contact 111 is lower than the bottom end of the first bottom plate 12 or is flush with the bottom end of the first bottom plate 12. In this embodiment, the bottom end of the upper contact 111 is lower than the bottom end of the first bottom plate 12; similarly, a third through hole 17 is provided on the first bottom plate 12, and the lighting system 5 is connected to the third through hole 17. The light of the lighting system 5 is irradiated downward through the third through hole 17. When the cover body 2 is connected to the shell body 1, the third through hole 17 is located directly above the liquid placement area 8. Opening the cover 2 means that the upper contact 111 and the lower contact 112 are separated, and the lighting system 5 is powered off. Closing the cover 2 means that the upper contact 111 and the lower contact 112 are in contact, the lighting system 5 is powered on, and the imaging chip 3 forms an image. For the imaging chip 3, since the liquid sample needs to be placed on the imaging chip 3, in order to ensure that the liquid sample is not contaminated during imaging observation, the cover 2 is provided for shielding. When in use, it is essential to open the cover 2 to place the sample and close the cover 2 before observation. Therefore, by providing the upper contact 111 and the lower contact 112, opening or closing the cover 2 corresponds to the disconnection and closure of the circuit, that is, the action of opening and closing the cover 2 required for observation itself is used to realize the on and off of the lighting system 5 circuit. Compared with a lensless microscope in which a switch for the lighting system 5 is separately provided, the structure is simpler, the operation is easier, and the cost is lower.

[0021] like Figure 1 As shown, the lower contact 112 is connected to the shell 1 and is located in the first installation cavity 6, the lower contact 112 is electrically connected to the imaging chip 3, and the first opening 7 is located directly above the liquid placement area 8, that is, the first installation cavity 6 only forms the first opening 7 directly above the liquid placement area 8 for the liquid sample to be placed therein, a second through hole 15 is provided on the upper end surface of the shell 1, a second annular protrusion 16 is circumferentially provided on the outer peripheral wall of the lower part of the lower contact 112, the lower end surface of the second annular protrusion 16 is flush with the lower end surface of the lower contact 112, the upper part of the lower contact 112 is inserted into the second through hole 15, the upper end surface of the lower contact 112 is higher than the upper end surface of the shell 1 or flush with the upper end surface of the shell 1, and in this embodiment, the upper end surface of the lower contact 112 is flush with the upper end surface of the shell 1; when the cover body 2 is connected to the shell 1, the upper contact 111 is in contact with and electrically connected to the lower contact 112, and when the cover body 2 is separated from the shell 1, the upper contact 111 is separated from the lower contact 112.

[0022] In addition, if Figure 1 As shown, the imaging chip 3 includes a first chip 31 and a second chip 32, the power supply module 4 includes a first power supply 41 and a second power supply 42, the first chip 31, the second chip 32, the first power supply 41 and the second power supply 42 are all connected to the shell 1 and are located in the first installation cavity 6, the first chip 31 is electrically connected to the first power supply 41, the second chip 32 is electrically connected to the second power supply 42, the first chip 31 and the second chip 32 are electrically connected, and the control component 11 is used to control the on and off of the electrical connection between the lighting system 5 and the first chip 31. Specifically, the lower contact 112 is electrically connected to the first chip 31, and the liquid placement area 8 is provided on the upper end surface of the second chip 32.

[0023] like Figure 1 As shown, the bottom end of the first chip 31 is connected to the bottom end of the interior of the housing 1 through a plurality of first support columns 18, the first chip 31 is located above the first power supply 41, the bottom end of the second chip 32 is connected to the bottom end of the interior of the housing 1 through a plurality of second support columns 19, and the second chip 32 is located above the second power supply 42; specifically, the housing 1 includes an outer cover 101 and a second bottom plate 102, the first mounting cavity 6 is disposed in the outer cover 101 and forms a first opening 7 on the upper end surface of the outer cover 101, the second through hole 15 is also disposed on the upper end surface of the outer cover 101, and the first The mounting cavity 6 forms a third opening 20 on the lower end surface of the outer cover 101, and the second base plate 102 is detachably connected to the inner wall of the outer cover 101. In this embodiment, the second base plate 102 is fixed to the outer cover 101 by bolts, and the first power supply 41, the second power supply 42, the first support column 18 and the second support column 19 are all connected to the second base plate 102, wherein there are four first support columns 18 and four second support columns 19, the first power supply 41 is located between the four first support columns 18, and the second power supply 42 is located between the four second support columns 19.

[0024] When the cover body 2 is separated from the shell 1, the liquid sample to be tested is placed into the liquid placement area 8 through the first opening 7, and then the cover body 2 is closed. After the cover body 2 is closed, the control component 11 is automatically turned on, and the power supply module 4 supplies power to the imaging chip 3 and the lighting system 5. The light of the lighting system 5 is irradiated through the first opening 7 to the liquid sample to be tested in the liquid placement area 8. The imaging chip 3 which integrates the image sensor chip technology and the intelligent image recognition technology images the liquid sample to be tested. The lensless microscopic imaging technology is used to break through the limitation of the space-bandwidth product brought by the lens of the traditional optical microscope. Under the premise of ensuring the imaging quality of the optical microscope equipment, the overall size of the microscope is smaller and the weight is lighter, and the cost is also greatly reduced.

[0025] The implementation modes of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned one implementation mode, and all other embodiments obtained by those skilled in the art without making any creative work are within the scope of protection of the present invention.

Claims

1. A lensless microscope, characterized in that: The invention comprises a shell (1), a cover (2), an imaging chip (3), a power supply module (4) and an illumination system (5); the shell (1) is provided with a first installation cavity (6), the first installation cavity (6) forms a first opening (7) on the upper end surface of the shell (1); the imaging chip (3) and the power supply module (4) are both connected to the shell (1) and are located in the first installation cavity (6); the upper end surface of the imaging chip (3) is provided with a liquid placement area (8); the cover (2) is provided with a second installation cavity (9), the second installation cavity (9) forms a second opening (7) on the lower end surface of the cover (2); 10), the lighting system (5) is connected to the cover body (2) and is located in the second installation cavity (9), the cover body (2) is detachably connected to the upper end of the shell (1), when the cover body (2) is connected to the upper end of the shell (1), the first opening (7) and the second opening (10) are closed and the lighting system (5) is located directly above the liquid placement area (8), the imaging chip (3) is electrically connected to the power supply module (4), and the cover body (2) is connected to a control component (11) for controlling the electrical connection between the lighting system (5) and the imaging chip (3).

2. The lensless microscope according to claim 1, characterized in that The control component (11) comprises an upper contact (111) and a lower contact (112); the upper contact (111) is connected to the cover body (2) and is located in the second installation cavity (9); the upper contact (111) is electrically connected to the lighting system (5); the lower contact (112) is connected to the shell (1) and is located in the first installation cavity (6); the lower contact (112) is electrically connected to the imaging chip (3); when the cover body (2) is connected to the shell (1), the upper contact (111) contacts and is electrically connected to the lower contact (112); when the cover body (2) is separated from the shell (1), the upper contact (111) is separated from the lower contact (112).

3. The lensless microscope according to claim 2, characterized in that: A first base plate (12) is provided in the second installation cavity (9), the first base plate (12) is connected to the inner wall of the cover body (2), a first annular protrusion (13) is circumferentially provided on the outer peripheral wall of the upper part of the upper contact (111), a first through hole (14) is provided on the first base plate (12), the upper contact (111) is inserted into the first through hole (14), the bottom end of the first annular protrusion (13) abuts against the upper end surface of the first base plate (12), and the bottom end of the upper contact (111) is lower than the bottom end of the first base plate (12) or is flush with the bottom end of the first base plate (12).

4. The lensless microscope according to claim 2, characterized in that: The first opening (7) is located directly above the liquid placement area (8); a second through hole (15) is provided on the upper end surface of the shell (1); a second annular protrusion (16) is provided on the outer peripheral wall of the lower part of the lower contact (112) along the circumferential direction; the lower contact (112) is inserted into the second through hole (15); the upper end surface of the lower contact (112) is higher than the upper end surface of the shell (1) or flush with the upper end surface of the shell (1).

5. The lensless microscope according to claim 1, characterized in that: A first base plate (12) is provided in the second installation cavity (9), the first base plate (12) is connected to the inner wall of the cover body (2), a third through hole (17) is provided on the first base plate (12), the lighting system (5) is connected to the third through hole (17), and light from the lighting system (5) is irradiated downward through the third through hole (17). When the cover body (2) is connected to the shell (1), the third through hole (17) is located directly above the liquid placement area (8).

6. The lensless microscope according to claim 1, characterized in that: The imaging chip (3) comprises a first chip (31) and a second chip (32); the power supply module (4) comprises a first power supply (41) and a second power supply (42); the first chip (31), the second chip (32), the first power supply (41) and the second power supply (42) are all connected to the housing (1) and are located in the first mounting cavity (6); the first chip (31) is electrically connected to the first power supply (41); the second chip (32) is electrically connected to the second power supply (42); the first chip (31) and the second chip (32) are electrically connected; the control component (11) is used to control the on / off of the electrical connection between the lighting system (5) and the first chip (31); and the liquid placement area (8) is provided on the upper end surface of the second chip (32).

7. The lensless microscope according to claim 6, characterized in that The bottom end of the first chip (31) is connected to the bottom end of the interior of the shell (1) via a plurality of first supporting columns (18), and the first chip (31) is located above the first power source (41). The bottom end of the second chip (32) is connected to the bottom end of the interior of the shell (1) via a plurality of second supporting columns (19), and the second chip (32) is located above the second power source (42).

8. The lensless microscope according to claim 7, characterized in that The shell (1) comprises an outer cover (101) and a second bottom plate (102); the first installation cavity (6) is arranged in the outer cover (101) and forms the first opening (7) on the upper end surface of the outer cover (101); the first installation cavity (6) forms a third opening (20) on the lower end surface of the outer cover (101); the second bottom plate (102) is detachably connected to the inner wall of the outer cover (101); the first power supply (41), the second power supply (42), the first support column (18) and the second support column (19) are all connected to the second bottom plate (102).