Portable isothermal amplification nucleic acid detection bag based on phase change heat release

By using a portable isothermal amplification nucleic acid detection bag based on phase change exothermics, isothermal amplification reaction and result visualization are achieved through phase change materials and a sealed structure. This solves the problems of complex structure and high cost of existing devices, and realizes low-cost and safe nucleic acid detection.

CN224199383UActive Publication Date: 2026-05-05XIAN INST OF QUALITY & STANDARDIZATION +1
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Patent Information

Application Number
CN202520720121.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-16
Publication Date
2026-05-05
Estimated Expiration
2035-04-16

AI Technical Summary

Technical Problem

Existing isothermal amplification nucleic acid detection devices are complex in structure and expensive, and require additional instruments and propulsion devices, which increases biosafety risks.

Method used

A portable isothermal amplification nucleic acid detection bag based on phase change exothermics is used. The phase change material is stored in the housing bag, and the isothermal amplification reaction is achieved through the sealed structure of the thermally conductive main reaction chamber and the enzyme-free water housing bag. The results are visualized by combining the flow chromatography test strip housing, thus avoiding dependence on instruments and equipment.

Benefits of technology

It enables isothermal amplification nucleic acid detection with simple structure and low cost, reduces dependence on instruments, ensures biosafety, and is suitable for home rapid testing.

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Abstract

The utility model discloses a portable isothermal amplification nucleic acid detection bag based on phase change heat release, which relates to the field of isothermal amplification nucleic acid detection, and comprises a phase change material mounting bag 101, and a heat conduction main reaction cabin, an enzyme-free water mounting bag and a flow measurement chromatography test strip mounting cabin which are arranged on the phase change material mounting bag 101, a first weak sealing strip is arranged on the enzyme-free water installation bag, an outlet of the heat conduction main reaction cabin is communicated with an inlet of the infusion apparatus, an outlet of the infusion apparatus is communicated with a liquid inlet of the flow measurement chromatography test strip installation cabin, and a second weak sealing strip is arranged on the infusion apparatus. The problems that a current isothermal amplification nucleic acid detection device is complex in structure and high in cost are solved, and instrument-free reaction and result visualization functions aiming at portable isothermal amplification reaction can be achieved.
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