To provide novel compounds for use in the treatment or prevention of
cancer and other proliferative conditions. [Solution] The present invention relates to novel compounds for use in the treatment or prevention of
cancer and other proliferative conditions, characterized, for example, by cells expressing
cytochrome P450 1B1 (CYP1B1) and its
allele variants. The present invention also provides pharmaceutical compositions comprising one or more such compounds for use in medical therapies, for example, in the treatment or prevention of
cancer or other proliferative conditions, as well as methods for treating cancer or other conditions in human or non-
human animal patients. The present invention also provides methods for identifying novel compounds for use in the treatment or prevention of cancer and other proliferative conditions, characterized, for example, by cells expressing CYP1B1 and its
allele variants. The present invention also provides methods for determining the
efficacy of the compounds of the present invention in
cancer treatment.