A
wireless universal serial
bus hub and an operation method thereof are provided. The
wireless universal serial
bus hub includes a local side device and a remote side device. The remote side device is communicatively connected to the local side device. The local side device receives at least one data, at least one check code, and at least one identifier from at least one first device respectively. The local side device generates a data packet based on the at least one data, the at least one check code, and the at least one identifier and wirelessly transmits the data packet to the remote side device. The remote side device generates serial differential data based on the data packet and outputs the serial differential data to a second device.