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Absorbable orthopedic apparatus material having antibiosis and bone growth promotion functions, and preparation method thereof
ActiveCN104127916AAbsorbablePromote growthSurgeryElectrophoretic coatingsOrthopaedic deviceBone growth
The invention relates to an absorbable orthopedic apparatus material having antibiosis and bone growth promotion functions, and a preparation method thereof. The orthopedic apparatus material is obtained by compounding medical pure magnesium or magnesium alloy with an absorbable high-molecular polymer, the surface of the pure magnesium or magnesium alloy has a porous ceramic layer, the surface of the porous ceramic layer is a functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as a carrier by adopting an electrophoresis-electrodeposition process, the volume fraction of the pure magnesium or magnesium alloy is 1-99%, the micropore aperture and the thickness of the porous ceramic layer on the surface of the pure magnesium or magnesium alloy are 1-100[mu]m and 1-100[mu]m respectively, and the surface of the porous ceramic layer is the functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as the carrier by adopting the electrophoresis-electrodeposition process. An orthopedic apparatus can slowly release copper ions having a sterilizing effect and bone morphogenetic proteins having a bone growth promotion effect in the use process, can be applied to restore and fix various bone injuries, and has a wide application prospect.
Owner:SOUTHEAST UNIV
Silk fibroin-alginate composite film, as well as preparation method and application thereof
InactiveCN106265129AChange conformationImprove mechanical propertiesCosmetic preparationsToilet preparationsComposite filmNon toxicity
The invention discloses a method for preparing a silk fibroin-alginate composite film, and belongs to the fields of composite materials and biotechnology. According to the method, brown algae extracted marine biomass sodium alginate serving as a substrate is mixed with waste silkworm cocoon extracted high-molecular-weight silk fibroin-alginate to prepare the dual-component composite film through tape casting by adopting supramolecular self-assembly and ionic crosslinking processes. The silk fibroin-alginate composite film has more intermolecular hydrogen-bond interactions, the comprehensive mechanical performance of the film can be improved, the moistening, water absorption and moisture absorption performance of the composite film can be remarkably improved due to the special interpenetrating mesh structure, and possibility is provided to loading of other sustained-release substances. The composite film is prepared from natural and green raw materials, and integrates excellent biocompatibility, non-toxicity, biodegradability and other properties of silk fibroin and sodium alginate, and can be applied to the industry of beautifying and skin-protecting masks. The preparation method is simple in preparation process, realizes solution recycling, is environmentally friendly, and has an excellent application prospect.
Owner:DALIAN POLYTECHNIC UNIVERSITY
Preparation method of anti-bacterial silver-ion ceramic
The invention discloses a preparation method of anti-bacterial silver-ion ceramic. The method comprises steps as follows: (1) ceramic clay serving as a ceramic preparation raw material is beat into slurry with a beater, the slurry is poured into a stirring machine to be stirred and mixed uniformly, then the slurry is injected into a ceramic mold, and a ceramic clay adobe is prepared; (2) an oxide containing silver is added to ceramic glaze and mixed uniformly, and silver-ion ceramic glaze containing an effective germicidal ingredient is prepared; (3) the ceramic glaze containing the silver ions is applied to the ceramic clay adobe, and a ceramic clay adobe coated with the silver-ion ceramic glaze containing the effective germicidal ingredient is prepared; (4) a photocatalyst with an anti-bacterial function is sprayed to the ceramic clay adobe coated with the silver-ion ceramic glaze containing the effective germicidal ingredient; (5) the ceramic clay adobe coated with the ceramic glaze and prepared in the step (4) is put into a kiln to be fired, and the anti-bacterial silver-ion ceramic is prepared. The ceramic prepared with the method has good anti-bacterial performance and can effectively inhibit bacterium breeding.
Owner:福建省德化县成艺陶瓷有限公司
Viscosity reduction high efficiency water-reducing polycarboxylate superplasticizer and preparation method thereof
The invention relates to a viscosity reduction high efficiency water-reducing polycarboxylate superplasticizer and a preparation method thereof. The superplasticizer is prepared by intermittent dropwise adding of macromonomers like TPEG monomer, unsaturated hydroxy acid monomer or its derivative, or unsaturated acid with a trans-structure for free radical polymerization reaction under the action of a reductant, an oxidant and a chain transfer agent. The anchoring group and side chain in the superplasticizer are molecular structures in block distribution, and can give full play to electrostaticrepulsion and steric-hinerance effect. In addition, the hydroxyl, carboxyl and other polar groups introduced by the unsaturated hydroxy acid monomer or its derivative monomer increase the proportionof hydrophilic groups and reduce the surface tension of the cement pore solution. In addition, in terms of the trans-structural body represented by fumaric acid and dihydroxyfumaric acid derivatives,because of the special structure, i.e. the stiffness of the monomer itself and the distribution of two carboxyl groups on the opposite side of the side chain, a stretching structure easily exhibits inspace to reduce the possibility of molecular chain entanglement and significantly increase the adsorption effect of the polycarboxylate superplasticizer on the cement surface, thereby enhancing the viscosity reduction effect of the polycarboxylate superplasticizer.
Owner:HUNAN UNIV
Self-assembled collagen-stimulated microsphere with naturally constituted shell-core structure and preparation method thereof
The invention discloses a self-assembled collagen-stimulated microsphere with a naturally constituted shell-core structure and a preparation method thereof. The electrostatic interaction between polycationic polymers and sodium hyaluronate (HA) is used to change the conformation of HA molecule and reduce the viscosity of HA neutral solution. The formation of micron-sized HA microspheres in emulsion system is promoted. The precipitation of microspheres is promoted by the electrostatic interaction between polycationic natural polymers and HA and by the condensation crosslinking reaction of amines and acids. The method skillfully solves the problem of high viscosity of high molecular weight HA neutral solution, and has the advantages of simple procedure and environmental protection. The prepared collagen-stimulated microspheres have a shell. The self-assembled structure of the nucleus is composed of natural macromolecules, which can be rapidly degraded by specific biological enzymes whenside reactions occur, thus ensuring the safety of injection products. At the same time, the microspheres have good mechanical strength and long degradation time, can effectively stimulate the secretion of collagen for a long time, and have good application prospects in the field of soft tissue filling, especially in the field of medical cosmetic filling.
Owner:SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD
Full-flexible transparent film electrode as well as preparation method and application thereof
PendingCN113611437AImprove conductivityImprove mechanical propertiesNon-insulated conductorsHybrid capacitor electrodesScreen printingThin film electrode
The invention relates to the technical field of flexible electrodes, and relates to a full-flexible transparent film electrode as well as a preparation method and application thereof. The full-flexible transparent film electrode and is formed by blending a water-soluble polymer serving as a dopant and a conductive polymer. The preparation method comprises the following steps of: dissolving a water-soluble polymer in a polar organic solvent, heating and stirring the water-soluble polymer and the polar organic solvent, uniformly stirring and mixing an obtained mixed solution with a PEDOT: PSS solution to obtain a full-flexible transparent film solution, dispensing the full-flexible transparent film solution on a substrate, and preparing a full-flexible transparent film on the substrate through spin coating, blade coating or screen printing; and annealing and drying the full-flexible transparent film and the substrate, then transferring the full-flexible transparent film and the substrate into water, separating the full-flexible transparent film from the substrate through ultrasonic treatment, thereby obtaining the full-flexible transparent film electrode. According to the full-flexible transparent film electrode provided by the invention, the prepared full-flexible transparent film electrode has good conductivity and transparency, also has good mechanical properties, and can bear a certain degree of strain.
Owner:NANJING UNIV OF POSTS & TELECOMM
Urine sample RNA stabilizing solution and preparation method thereof
PendingCN110760567AAchieve preservationRealize transportationMicrobiological testing/measurementUrine sampleUltrapure water
The invention discloses a urine sample RNA stabilizing solution and a preparation method thereof. The urine sample RNA stabilizing solution is prepared from 0.01 to 2M of dithiothreitol, 2M to 6M of guanidinium isothiocyanate, 1 to 200 mM of ethylenediamine tetraacetic acid, 0.05 to 0.5 mM of diethyl pyrocarbonate and ultrapure water. The preparation method comprises the following steps: adding acertain amount of the chemical reagent into ultrapure water, adjusting the pH value to 4-4.2 with hydrochloric acid, fixing the volume, and carrying out sealed storage. The urine sample RNA stabilizing solution provided by the invention can effectively maintain the stability of RNA in a urine sample, can realize preservation and transportation of large-volume urine, and is suitable for subsequentRNA extraction and fluorescent RT-PCR.
Owner:HANGZHOU YORK BIOTECH CO LTD
Artificial ligament and preparation method thereof
ActiveCN103315827APromotes collagen synthesisGood biocompatibilityLigamentsMusclesFiberPolyethylene glycol
The invention provides an artificial ligament which comprises an inner core and an outer layer from inside to outside in sequence. The inner core is made of ozonized polyethylene glycol terephthalate, and the outer layer is made of polysaccharide or polymer polymerized from hydrophilic group contained allyl monomer and is grafted on a free radical locus of the inner core. A preparation method of the artificial ligament includes: subjecting a ligament of a polyethylene glycol terephthalate material to reaction with ozone so as to obtain the polyethylene glycol terephthalate with a free radical; under protection of inert gas, subjecting a solution containing monomer molecules and the polyethylene glycol terephthalate containing the free radical to sealed polymerization reaction so as to obtain the artificial ligament. The artificial ligament is good in biocompatibility, and capable of restraining bacterial infection, changing protein conformation adhered on surface of a material, reducing inflammation and promoting adhering, growing and fibroblast of fibroblast after being planted in a human body. Collagen protein synthesis on the surface of the artificial ligament is improved, and infiltration of new ligament tissue is facilitated.
Owner:周婕
Preparation method for rice milk beverage with pleasant flavor
InactiveCN107365653AImprove functional propertiesIncreased soluble protein contentAlcoholic beverage preparationFlavorAlkaline protease
The invention discloses a preparation method for a rice milk beverage with pleasant flavor. The preparation method comprises the following steps that rice is pretreated and then placed into a water bath vibrator, alkaline protease is added for enzymolysis, inactivation is conduced, and the system pH value is adjusted to be neutral; micronization treatment is conducted, dried yeast is added for fermentation, sterilization and spray drying are conducted, and then a first material is obtained; water is added into the first material, the system pH value is adjusted to be 6.4-6.7, gelatinization treatment is conducted, and then a second material is obtained; and maltose, sodium alginate and sodium carboxymethylcellulose are added into the second material and then are stirred to be uniform, olive oil is added to conduct emulsification treatment, then a mixture is sent to be subjected to homogenization treatment, sterilization is conducted, and then the rice milk beverage with the pleasant flavor is obtained. According to the preparation method, the obtained rice milk beverage is smooth and rich in tasting, rich in fragrance, extremely rich in nutrient substance and low in cost.
Owner:全椒县崇明米业有限公司
Preparation method of antibacterial domestic ceramic
The invention relates to the technical field of ceramic aspects and discloses a preparation method of an antibacterial domestic ceramic. The method comprises the following steps of: beating ceramic clay as raw materials for preparing ceramics into slurry by using a beating machine, pouring the slurry into a stirrer to stir and mix uniformly, injecting the slurry to a ceramic die, automatically airing to be dry, uniformly evaporating water, airing to be dry, then releasing the die, preparing a ceramic clay blank, and preparing the antibacterial domestic ceramic. The antibacterial domestic ceramic prepared by using the method is good in antibacterial performance.
Owner:林潮清
Hygrothermal complex enzyme treatment method for conditioning rice starch macromolecule texture physical property
The invention provides a hygrothermal complex enzyme treatment method for conditioning the rice starch macromolecule texture physical property. The method includes the following steps that 1, rice is soaked in water, the pH value is adjusted to range from 5.0 to 8.0, and pretreatment is carried out at the temperature of 40-80 DEG C; 2, the pH value of the pretreated mixture of the rice and the water is adjusted to range from 4.5 to 7.5, the temperature is controlled to range from 30 DEG C to 40 DEG C, and protease is added for enzymolysis; 3, the pH value is kept to range from 4.5 to 7.5, the temperature is controlled to range from 25 DEG C to 50 DEG C, a-amylase is added, and a stirring reaction is carried out; 4, the pH value is adjusted to range from 3.0 to 6.0, the temperature is controlled to range from 40 DEG C to 70 DEG C, pullulanase is added, a stirring reaction is carried out, and enzyme deactivation is carried out; 5, stage drying is carried out at the temperature of 100+ / -3 DEG C to 80+ / -3 DEG C to 60+ / -3 DEG C, and the water content of the rice is smaller than 10 wt%. The rice starch macromolecule texture physical property can be effectively conditioned in order to adjust and control the quality of rice food.
Owner:CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY +2
Method for passivating rice bran lipase through supercritical CO2 extrusion
PendingCN111602766AChange conformationKeep heat sensitive ingredientsGaseous food ingredientsSupercritical fluidBiotechnology
The invention provides a method for passivating rice bran lipase through supercritical CO2 extrusion. Extrusion is a high-temperature short-time treatment process, can destroy cell structures and enable grease to be fully exposed, but high temperature and high shearing force cause certain loss of heat-sensitive components in food. And the supercritical fluid belongs to a solvent-free system and has the characteristics of no toxicity, no harm, lower production cost and the like. The density of the supercritical CO2 can be changed in a wide range, so that the supercritical CO2 has high dissolving capacity for many substances, and heat-sensitive components and unstable natural products can be protected from being damaged. Through supercritical CO2 extrusion, lipase activity in the rice bran is effectively passivated, the rice bran is stabilized, heat-sensitive components in the material are well preserved, the content of vitamin E is 150.45 mg / kg, and the content of gamma-sitosterol is 2.81 mg / g. According to the method, technical parameters of supercritical CO2 extrusion are optimized, and finally the stable rice bran is obtained.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY
Eugenol combination liquid as well as preparation method and application thereof
InactiveCN107019138AEnsure hygiene and safetyReduce usageFood preservationFood ingredient for microbe protectionEugenolStaphylococcus aureus
The invention provides a eugenol combination liquid as well as a preparation method and an application of the eugenol combination liquid. The combination liquid comprises the following raw materials by volume: 99.8555%-99.9711% of water, 0.01%-0.05% of Tween 80 solution, and 0.0189%-0.0945% of eugenol; and the invention provides the method for preparing the eugenol combination liquid. The eugenol combination liquid inhibits the growth of staphylococcus aureus, and can even be used as a bactericide when the concentration of the eugenol is higher. The eugenol combination liquid affects the molecular structures of an SDH enzyme and an MDH enzyme of staphylococcus aureus, and the staphylococcus aureus is changed, so that the conformation is changed, and the activity of the enzyme is reduced. After the eugenol combination liquid acts on the staphylococcus aureus, the nucleic acid substances related to the synthesis of protein are leaked because of the change of cell permeability, the synthesis of the protein is further inhibited, and finally the cell death is caused.
Owner:FOSHAN UNIVERSITY
Preparation method of fiber rubber type shock-absorbing material
The invention discloses a preparation method of a fiber rubber type shock-absorbing material and belongs to the technical field of preparation of shock-absorbing materials. The preparation method comprises the following steps: firstly, mixing and grinding silicon carbide and silicon nitride to obtain mixed powder; then melting and spinning the mixed powder to obtain self-made mixed fibers. As in asystem, the self-made mixed fibers are connected through staggered base material molecular chains, the surface of the vegetable sponge is modified by means of an alkaline solution, so that cutin andwax coats on the surfaces of cell walls of the vegetable sponge are removed favorably, and the extent of crystallization and polymerization of cellulose is reduced. In addition, the modified vegetablesponge particles are carbonized to prepare self-made activated carbon. Once being impacted by an external force, segmental motions of a base material are constrained by means of the self-made activated carbon. By adding trimethylolpropane trimethacrylate continuously and carrying out high-temperature irradiation crosslinking modification, twining and interaction among the molecular chains of thebase material are improved, so that the base material has higher cell density and more uniform pore distribution, and therefore, the heat dissipating property of the shock-absorbing material is further improved. The material has a wide application prospect.
Owner:吴伟华
A kind of method that utilizes rice dregs to prepare rice protein functional drink
ActiveCN104256825BHigh extraction rateQuality improvementFood homogenisationBiotechnologyVegetable oil
The invention discloses a method for preparing a rice protein functional drink by using rice dregs, and belongs to the technical field of rice deep processing. In the present invention, the rice dregs are soaked in warm water and then subjected to ultrasonic pretreatment, followed by two high-pressure homogeneous treatments under the conditions of 30-55 MPa instantaneously to obtain the upper light phase material and the lower layer heavy phase starch liquid, and the upper layer light phase material to maintain Keep the pressure at 90-100MPa for 20 minutes, concentrate to obtain heavy-phase protein slurry; concentrate and dry the lower-layer heavy-phase starch liquid to obtain starch; add purified water to the protein slurry to adjust the pH value; add starch, heat up to 80-85°C, and gelatinize at 0.5 Hours; add white sugar, thickener, stabilizer, stir well; add vegetable oil containing spaghetti, and emulsify in the mixing pot for 10 minutes; add flavoring agent, stir evenly, keep warm at 75-85°C, and sterilize and pack. The invention improves the extraction rate and purity of the rice protein and enhances the extracted protein quantity, and the rice protein is made into a cereal beverage, which is nutritious and healthy, and has low cost.
Owner:ANHUI LEHUANTIAN BIOTECH
Method for passivating rice bran lipase under action of supercritical CO2 solvent synergistic pressure
The invention provides a method for passivating rice bran lipase under the action of supercritical CO2 solvent synergistic pressure. CO2 gas is a medium widely applied to food processing, is low in price, and has higher purity of obtained components. CO2 is used as an inert medium and can play a protection role in heat sensitive components in a raw material, and the CO2 gas is rather safe and easyto operate when applied to food processing. Rice bran is processed by using the action of the supercritical CO2 solvent synergistic pressure, conformation of enzyme can be effectively changed, the enzyme is passivated and inactivated, and a NSI value in the stabilized rice bran can reach 80%. After an eight-week storage test, the free fatty acid content in the rice bran is less than 5% after extrusion and puffing treatment is carried out CO2, a peroxide value is in a threshold range of 5mmol / kg, and utilization ratio of the rice bran is effectively improved. According to the method for passivating the rice bran lipase under the action of the supercritical CO2 solvent synergistic pressure, technical parameters of the passivated rice bran lipase under the action of the supercritical CO2 solvent synergistic pressure are optimized, and finally, the stabilized rice bran is obtained.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY
Blood collection tube capable of protecting and stabilizing of gastrin-releasing peptide precursor in serum or plasma
ActiveCN108279307ALong storage timeEasy to operate and applyDiagnostic recording/measuringSensorsBlood Collection TubeAprotinin
The invention discloses a blood collection tube with a function of protecting and stabilizing of a gastrin-releasing peptide precursor in serum or plasma. The blood collection tube comprises a test tube; a sealing rubber plug and a plastic outer cap are arranged at an opening of the test tube; the test tube is internally pre-filled with a protective agent prepared from casein, sodium dodecyl sulfate and aprotinin. The blood collection tube is internally pre-filled with the protective agent, so that the preservation time of a ProGRP sample is greatly prolonged (the sample can be stably preserved for 7 days at 2-8 DEG C), and the clinical operation application is also facilitated; when the test result of the individual sample is suspected to be abnormal, the test can be repeated, so that theprobability of false negative results is reduced, and the accuracy and clinical application value of the test results of the item are improved.
Owner:AUTOBIO DIAGNOSTICS CO LTD
A kind of preparation method of high tenacity silk fibroin gel
The invention discloses a preparation method of high tenacity silk fibroin gel. Ordinary silk fibroin solution undergoes crystallization-inducing treatment to obtain crystalline silk fibroin solution, then mixes it with ordinary silk fibroin solution, and finally obtains high-tenacity silk fibroin gel under the action of self-assembly. This technology can control the gelation time, toughness and other properties of hydrogel by changing the concentration of silk fibroin solution, the size and content of crystalline silk fibroin, self-assembly temperature and other parameters. The preparation process of the present invention is mild, no toxic organic reagents such as cross-linking agents are needed, the preparation conditions are green and controllable, and there is no waste residue, which provides a new method for the preparation of functional hydrogels and can be used in biomedicine and tissue engineering and other fields.
Owner:HANGZHOU DIANZI UNIV
A self-assembled collagen-stimulated microsphere with a natural shell-core structure and its preparation method
ActiveCN109224127BChange conformationLow viscosityTissue regenerationProsthesisMicrosphereEngineering
The invention discloses a self-assembled collagen stimulating microsphere with a natural shell-core structure and a preparation method thereof. Utilize the electrostatic interaction between polyamino polycationic natural polymer and sodium hyaluronate (HA) to change the conformation of HA molecules, reduce the viscosity of high molecular weight HA neutral solution, and promote the formation of micron-sized HA microspheres in the emulsification system . Utilize the electrostatic interaction between polyamino polycationic natural polymer and HA and the condensation and cross-linking reaction of acid amine to promote the precipitation of microspheres. The method skillfully solves the problem of high viscosity of high molecular weight HA neutral solution, and has simple steps and environmentally friendly technical route. The prepared collagen-stimulated microspheres have a shell-core self-assembly structure, and the components are all natural polymers, which can be rapidly degraded by specific biological enzymes when side reactions occur, ensuring the safety of product injections; at the same time, the microspheres have good Excellent mechanical strength and long degradation time can effectively stimulate collagen secretion for a long time, and have a good application prospect in the field of soft tissue filling, especially medical cosmetic filling.
Owner:SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD
A kind of viscosity-reducing high-efficiency water-reducing polycarboxylate water-reducer and its preparation method
A viscosity-reducing high-efficiency water-reducing polycarboxylate water-reducer and its preparation method, the water-reducer is composed of macromonomers such as isopentenol polyoxyethylene ether monomers, unsaturated hydroxy acid monomers or derivatives thereof, Or the unsaturated acid with trans structure is prepared by free radical polymerization under the action of reducing agent, oxidizing agent and chain transfer agent by intermittent dropping. The anchor groups and side chains in the water reducer of the present invention are block-distributed molecular structures, which can give full play to the electrostatic repulsion and steric hindrance effects; in addition, the hydroxyl groups introduced by unsaturated hydroxyacid monomers or their derivative monomers Polar groups such as carboxyl and carboxyl groups increase the proportion of hydrophilic groups and reduce the surface tension of the cement pore solution; in addition, the trans structure represented by fumaric acid and dihydroxy fumaric acid derivatives, due to its special The structure, that is, the rigidity of the monomer itself and its two carboxyl groups are distributed on the opposite side of the side chain, which makes it easy to show a stretched structure in space, reduces the possibility of molecular chain entanglement, and significantly increases the polycarboxylate superplasticizer. Adsorption on the surface of cement, thereby improving the viscosity-reducing effect of polycarboxylate superplasticizer.
Owner:HUNAN UNIV
A kind of pleiotropic polyclonal antibody for animals, its preparation method and application
ActiveCN105968194BBroad resistance spectrumWide range of therapeutic effectsSerum immunoglobulinsAntibody ingredientsSerum igeImmunoglobulin IgE
The invention discloses a multiple-effect polyclone antibody for animals, prepared according to the following method with steps of: A, adopting grouped poly immunogen polypeptide as immunogen, which at least contains the sequence of the immunogen polypeptides as shown in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, or a sequence with immunogenicity derived from the sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 by substituting, deleting, and / or adding one or more amino acid; B, immunizing animals: immunizing a target animal with the immunogen polypeptide of the step A and obtaining antiserum; and C, obtaining polyclone antibody: separating and purifying the antiserum immunoglobulin obtained in the step B to obtain the polyclone antibody. The polyclone antibody disclosed by the invention has extensive application in preparing integrate disease control drugs and immunopotentiating drugs for livestock.
Owner:河北普德动物药业有限公司
Absorbable orthopedic device material with antibacterial and bone growth promoting functions and preparation method
ActiveCN104127916BAbsorbablePromote growthSurgeryElectrophoretic coatingsDevice materialOrthopedic apparatus
The invention relates to an absorbable orthopedic apparatus material having antibiosis and bone growth promotion functions, and a preparation method thereof. The orthopedic apparatus material is obtained by compounding medical pure magnesium or magnesium alloy with an absorbable high-molecular polymer, the surface of the pure magnesium or magnesium alloy has a porous ceramic layer, the surface of the porous ceramic layer is a functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as a carrier by adopting an electrophoresis-electrodeposition process, the volume fraction of the pure magnesium or magnesium alloy is 1-99%, the micropore aperture and the thickness of the porous ceramic layer on the surface of the pure magnesium or magnesium alloy are 1-100[mu]m and 1-100[mu]m respectively, and the surface of the porous ceramic layer is the functional load layer loaded with bone morphogenetic proteins and copper ions with B-type gelatin as the carrier by adopting the electrophoresis-electrodeposition process. An orthopedic apparatus can slowly release copper ions having a sterilizing effect and bone morphogenetic proteins having a bone growth promotion effect in the use process, can be applied to restore and fix various bone injuries, and has a wide application prospect.
Owner:SOUTHEAST UNIV
A kind of preparation method of silk fibroin thixotropic gel
Owner:HANGZHOU DIANZI UNIV
Multiple-effect polyclone antibody for animals as well as preparation method and application thereof
ActiveCN105968194ABroad resistance spectrumWide range of therapeutic effectsSerum immunoglobulinsAntibody ingredientsDiseaseSerum ige
The invention discloses a multiple-effect polyclone antibody for animals, prepared according to the following method with steps of: A, adopting grouped poly immunogen polypeptide as immunogen, which at least contains the sequence of the immunogen polypeptides as shown in SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3, or a sequence with immunogenicity derived from the sequences of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3 by substituting, deleting, and / or adding one or more amino acid; B, immunizing animals: immunizing a target animal with the immunogen polypeptide of the step A and obtaining antiserum; and C, obtaining polyclone antibody: separating and purifying the antiserum immunoglobulin obtained in the step B to obtain the polyclone antibody. The polyclone antibody disclosed by the invention has extensive application in preparing integrate disease control drugs and immunopotentiating drugs for livestock.
Owner:河北普德动物药业有限公司
Method for efficiently co-producing maltose syrup and rice protein by rice processing by-products
ActiveCN106755204BHigh extraction rateImprove solubilityMicroorganism based processesFermentationBiotechnologyAmylase
The invention discloses a method for realizing efficient co-production of malt syrup and rice protein by adopting rice processing by-products. Broken rice and rice bran are adopted as the raw materials. The method comprises the following processing steps: (1) carrying out mechanical pretreatment; (2) carrying out ultrasonic treatment; (3) carrying out mild biological activating; (4) carrying out degreasing pretreatment; (5) carrying out hydrolysis and liquefying by adopting alpha-amylase; (6) carrying out separating, namely, carrying out centrifugalizing on the liquefied liquid obtained in the step (3) at 3200r / min, thus obtaining the supernate and sediment; (7) preparing broken rice and rice brain protein; (8) carrying out modified treatment on saccharifying enzyme; and (9) preparing the broken rice and rice bran malt syrup. With the adoption of the method provided by the invention, the malt syrup and rice protein by-products with good quality can be prepared, and the utilization value of the rice processing by-products is favorably improved.
Owner:无锡甜丰食品有限公司
A kind of preparation method of high foaming egg white liquid with long shelf life
ActiveCN108477526BChange structural propertiesImprove heat resistanceEggs preservation by irradiation/electric treatmentEggs preservation by heatingEnzymatic hydrolysisProcess engineering
Owner:NORTHEAST AGRICULTURAL UNIVERSITY
Method for efficiently co-producing maltodextrin and rice protein by rice processing by-products
The invention discloses a method for efficiently co-producing maltodextrin and rice protein through rice processing byproducts. The method is characterized in that broken rice and rice bran are used as the raw materials. The method comprises the following processing steps: (1) mechanically crushing; (2) ultrasonically processing; (3) lightly biologically activating; (4) debranching and preprocessing; (5) hydrolyzing and liquidating with alpha-amylase; (6) separating; (7) preparing broken rice and rice bran protein; (8) preparing broken rice and rice bran maltodextrin. With the adoption of the method, high-quality broken rice and rice bran maltodextrin and rice protein byproducts can be prepared, so that the utilization value of the rice processing byproducts can be further increased.
Owner:无锡甜丰食品有限公司
Blood collection tubes for protection and stabilization of gastrin releasing peptide precursor in serum or plasma
ActiveCN108279307BLong storage timeEasy to operate and applyDiagnostic recording/measuringSensorsBlood Collection TubeBlood plasma
The invention discloses a blood collection tube with the function of protecting and stabilizing the precursor of gastrin releasing peptide in serum or plasma, comprising a test tube, a sealing rubber plug and a plastic outer cap are arranged at the opening of the test tube, and the test tube is prefilled with cheese Protectant formulated with protein, sodium lauryl sulfate and aprotinin. Because the protective agent is pre-filled in the blood collection tube, the storage time of the ProGRP sample is greatly extended (the sample can be stored stably for 7 days at 2-8°C). On the one hand, it is convenient for clinical operation and application. Retesting can be carried out, which reduces the probability of false negative test results and improves the accuracy and clinical application value of the test results of this item.
Owner:AUTOBIO DIAGNOSTICS CO LTD
A method for making a photoinduced energy storage fluorescent painting
ActiveCN108515804BEasy to storeChange conformationNon-macromolecular adhesive additivesProtein adhesivesAdhesiveFluorescence
Owner:麻鑫
A kind of preparation method of artificial ligament
ActiveCN103315827BPromotes collagen synthesisGood biocompatibilityLigamentsMusclesFiberPolyethylene glycol
The invention provides an artificial ligament which comprises an inner core and an outer layer from inside to outside in sequence. The inner core is made of ozonized polyethylene glycol terephthalate, and the outer layer is made of polysaccharide or polymer polymerized from hydrophilic group contained allyl monomer and is grafted on a free radical locus of the inner core. A preparation method of the artificial ligament includes: subjecting a ligament of a polyethylene glycol terephthalate material to reaction with ozone so as to obtain the polyethylene glycol terephthalate with a free radical; under protection of inert gas, subjecting a solution containing monomer molecules and the polyethylene glycol terephthalate containing the free radical to sealed polymerization reaction so as to obtain the artificial ligament. The artificial ligament is good in biocompatibility, and capable of restraining bacterial infection, changing protein conformation adhered on surface of a material, reducing inflammation and promoting adhering, growing and fibroblast of fibroblast after being planted in a human body. Collagen protein synthesis on the surface of the artificial ligament is improved, and infiltration of new ligament tissue is facilitated.
Owner:周婕
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