The invention relates to the technical field of coatings, and particularly discloses a water-based acrylic amino baking paint and a preparation method thereof. The water-based acrylic amino baking paint comprises, by mass, 15-30% of an epoxy modified acrylic resin, 5-10% of organic silicon and organic fluorine copolymer resin, 4-10% of high methylated melamine resin, 3-5% of a cosolvent, 2-4% of glass powder, 1-2% of a pH regulator, 0.5-1% of an antifoaming agent, 0.5-1.5% of a dispersant, 0.3-0.5% of a base material wetting agent, 0.5-1% of nano-silver, 1-2% of siloxane, 3-5% of a nanometer metal oxide dispersion, 0.2-0.4% of a leveling agent, 10-25% of a pigment, and the balance of deionized water. The water-based acrylic amino baking paint has the advantages of good wear resistance, strong adhesive force, good water resistance, good weather resistance, good impact resistance, and no sweat retention or bacteria breeding on the surface.