The invention discloses a non-benzene harmless diluent which comprises, by mass percent, 55-70% of acetal-type or ethanol mixtures, 23-30% of aliphatic carboxylic acid derivatives, 5-7% of aliphatic alcohol, 2-5% of ketone solvents and 0-3% of solvents with multifunctional groups. According to the non-benzene harmless diluent, the preparation is easy, the cost is low, the dissolving capacity is strong, the evaporation speed is high, and the film-forming time is short, so that paint films are shining, blushing of the paint films does not occur, and the anti-humidity property and the heat-resistant property are improved; the non-benzene harmless diluent can dissolve and dilute materials of cellulose acetate, nitrated cellulose, resin and rubber, cellulose ether, chlorinated rubber, synthetic resin, coatings and paint.