Paracetamol effervescent granule and identification method thereof

A technology of acetaminophen and effervescent granules, applied in the direction of anhydride/acid/halide active ingredients, etc., can solve the problem that acid and alkali agents cannot be mixed with drugs and other excipients at the same time, and the drug efficacy cannot be well exerted. , unfavorable large-scale production operations and other problems, to achieve the effect of being suitable for industrial production, improving identification items, and good compliance
CN102743366BActive Publication Date: 2013-11-20HAINAN HULUWA PHARMA GRP CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN HULUWA PHARMA GRP CO LTD
Publication Date
2013-11-20

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Abstract

The invention discloses a paracetamol effervescent granule. The paracetamol effervescent granule comprises, by weight, 2%-7% paracetamol, 5%-30% of effervescing agents, 65%-86% of filler, 0.6%-0.8% of flavoring agents and the balance bonding agents, the effervescing agents are composed of acid agents and alkaline agents, the mass ratio of the acid agents to the alkaline agents is 1:1.7, the acid agents are optionally two or three of citric acid, fumaric acid and tartaric acid, and the alkaline agents are sodium bicarbonate. The paracetamol effervescent granule is dissolved in water quickly to form clear and transparent solution great in taste, and is convenient to take, high in bioavailability, qualified in identification items and good in effervescence. The invention further discloses an identification method of the paracetamol effervescent granule, and the identification method is simple in operation and good in anti-interference effect.
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Description

technical field

[0001] The invention relates to the field of pharmaceutical preparations, in particular to a paracetamol effervescent granule and an identification method thereof. Background technique

[0002] A cold is an infection of the upper respiratory tract mucosa caused by many different types of viruses. Its main symptoms are nasal congestion, sneezing, dry cough, mild sore throat, and fever. Systemic symptoms include general discomfort, headache, and myalgia. The use of symptomatic treatment promotes the relief of many symptoms of the common cold. Since there is no drug that can relieve many coexisting symptoms at the same time, various compound preparations have been listed one after another. These compound preparations are composed of drugs with different curative effects to relieve different symptoms that exist at the same time. If the patient has multiple symptoms, especially in the early stage of a cold, it is more appropriate and sometimes more economical to...

Claims

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