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Application of camptosorus sibiricus total flavonids in preparation of medicines for preventing and treating tumour

A technology of total flavonoids and mountain fern, which is applied in the direction of antineoplastic drugs, drug combinations, medical raw materials derived from ferns/filamentous plants, etc., can solve the problem that the etiology of tumors is not completely clear

Active Publication Date: 2014-07-16
河南金丝指生物科技有限公司
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Problems solved by technology

[0002] Tumor is a major disease that seriously endangers human health. Although traditional treatment methods such as surgery, chemotherapy and radiotherapy have greatly improved the control of early tumors, due to the concealment of early tumor symptoms, most malignant tumors are in the middle stage when they are discovered. In the advanced stage, and the etiology of tumor occurrence is not completely clear, it is still an important task for tumor research to further explore the cause of tumor occurrence and discover new therapeutic drugs

Method used

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  • Application of camptosorus sibiricus total flavonids in preparation of medicines for preventing and treating tumour
  • Application of camptosorus sibiricus total flavonids in preparation of medicines for preventing and treating tumour
  • Application of camptosorus sibiricus total flavonids in preparation of medicines for preventing and treating tumour

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Embodiment Construction

[0023] The present invention has tested the total flavonoids of Glycyrrhizae as a lysine oxidase inhibitor and its application in tumors. The total flavonoids of Glycyrrhizae are effective for oral administration and injection. example.

[0024] The total flavonoids used in the experiment were obtained by the following method: after degreasing the washed, dried, and pulverized aboveground whole herb of Pteris supernatae with petroleum ether, use ethanol aqueous solution with a volume concentration of 55% according to the ratio of liquid to material. Extract twice at 30:1 at 85°C, each time for 2 hours, filter, combine the extracts and concentrate to the equivalent of 0.1g of the original medicinal material per ml, respectively pass through 95% ethanol (the amount added is based on the ethanol concentration accounting for 80% of the total volume of the solution) preferably), 70% ethanol (the amount added should be 50% of the total volume of the solution), each alcohol precipita...

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Abstract

The present invention belongs to the technical field of application of total flavonoids of fern, and specifically relates to the application of total flavonoids of fern as a lysine oxidase inhibitor in the preparation of drugs for the prevention and treatment of tumors, such as the prevention of chemical carcinogenesis (such as lung cancer, breast cancer and Skin cancer caused by ultraviolet rays, etc.), prevent tumor cell growth and metastasis, enhance the effect of tumor chemotherapy, etc.

Description

technical field [0001] The present invention belongs to the technical field of application of total flavonoids of fern, and specifically relates to the application of total flavonoids of fern as a lysine oxidase inhibitor in the preparation of drugs for the prevention and treatment of tumors, such as the prevention of chemical carcinogenesis (such as lung cancer, breast cancer and Skin cancer caused by ultraviolet rays, etc.), prevent tumor cell growth and metastasis, enhance the effect of tumor chemotherapy, etc. Background technique [0002] Tumor is a major disease that seriously endangers human health. Although traditional treatment methods such as surgery, chemotherapy and radiotherapy have greatly improved the control of early tumors, due to the concealment of early tumor symptoms, most malignant tumors are in the middle stage when they are discovered. In the advanced stage, and the etiology of tumor occurrence is not completely clear at present, it is still an importa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/11A61P35/00
Inventor 杜钢军卢琳琳杨义明林海红张亚平孙婷刘伟杰李佳桓刘迎辉赵贝李鸿儒侯西栋
Owner 河南金丝指生物科技有限公司
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