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Hydroxyl phenylalanine tyrosine urine detecting kit

A technology of hydroxyphenylalanine and detection reagents, which is applied in the direction of material analysis by observing the influence on chemical indicators, and analysis by chemical reaction of materials, etc., can solve the difficulty of sensitivity and specificity of cancer screening reagents, etc. question

Inactive Publication Date: 2015-12-23
朱建华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Cancer screening reagents need to have good sensitivity and specificity, but sensitivity and specificity are a pair of contradictions, improving sensitivity will reduce specificity, the components in human urine are very complex, any physiological changes will make urine Therefore, the sensitivity and specificity of cancer screening reagents is a difficulty in this field

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0046] Embodiment 1, p-hydroxyphenylalanine tyrosine urine detection reagent, the detection reagent is at least mixed with acid solution, phosphomolybdic acid and / or phosphomolybdic acid soluble salt, and the acidic solution contains at least H + 、Ni 2+ , Hg + , NO 3 - ion, the concentration of the phosphomolybdic acid and / or the soluble salt of phosphomolybdic acid in the detection reagent is 45-900mmol / L.

Embodiment approach 2

[0047] Embodiment 2 is the same as Embodiment 1, except that the Hg in the detection reagent + The concentration ratio of the concentration of phosphomolybdic acid is 1:0.9-2.

Embodiment approach 3

[0048] Embodiment 3 is the same as Embodiment 1, except that the Hg in the detection reagent + The concentration is 50-1000mmol / L.

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PUM

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Abstract

The invention provides a hydroxyl phenylalanine tyrosine urine detecting kit, and the detecting kit is at least mixed from an acidic solution, phospho molybdic acid and / or a soluble salt of phosphomolybdic acid; the acidic solution at least contains H+, Ni2+, Hg+ and NO3-, and the concentration of phosphomolybdic acid and / or the soluble salt of phosphomolybdic acid in the detecting kit is 45-900 mmol / L. The detecting kit has a higher detection accuracy.

Description

technical field [0001] The invention relates to a urine detection reagent for p-hydroxyphenylalanine tyrosine, and also relates to a detection method for monohydric phenolic metabolites in human urine. Background technique [0002] Early screening of cancer is a very important means to reduce cancer morbidity and mortality. Currently common detection methods include various tumor markers, infrared rays, X-rays, etc. Tumor markers need to go to the hospital to draw blood, and special equipment is needed for detection. The same is true for infrared rays and X-rays. The current screening methods all involve various instruments and equipment, which are complicated and costly. The detection of tumor markers in urine has always been a research hotspot in the world, and the use of tumor markers in urine to screen early cancers has been generally recognized by scientific researchers and consumers. [0003] Cancer screening reagents need to have good sensitivity and specificity, b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/78
Inventor 朱建华
Owner 朱建华
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