Dongchuan pig general disease resistance comprehensive selection index selection breeding method

A comprehensive selection index and selective breeding technology, applied in animal husbandry and other directions, can solve the problem of inability to comprehensively evaluate the ability of individual immune response.

Inactive Publication Date: 2017-12-22
YANGZHOU UNIV
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Problems solved by technology

But so far, there is no evaluation system for the general disease resistance of pigs, and it is impossible to comprehensively evaluate the individual immune response ability. This has become a bottleneck problem in the breeding practice of pigs to improve the general disease resistance. The establishment of pig immunity index, Systematic research on in vitro methods and their relationship with actual disease resistance has become an urgent task and the key to breeding pig breeds with general resistance

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  • Dongchuan pig general disease resistance comprehensive selection index selection breeding method
  • Dongchuan pig general disease resistance comprehensive selection index selection breeding method
  • Dongchuan pig general disease resistance comprehensive selection index selection breeding method

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Embodiment Construction

[0024] The present invention will be further described below in conjunction with specific examples.

[0025] 1. Determination of general disease resistance indexes (important cytokines) of Dongchuan pigs

[0026] Before the implementation of the present invention, the research group utilized the determination of interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 6 (IL- 6), interleukin 10 (IL-10), interleukin 12 (IL-12) and beta interferon (IFN-β) to evaluate the general disease resistance of the population, use interleukin 1β (IL-1β), Interleukin 4 (IL-4), Interleukin 6 (IL-6), Interleukin 8 (IL-8), Interleukin 10 (IL-10), Transforming Growth Factor β (TGF-β), Tumor Necrosis Factor α (Tumor Necrosis Factor , TNF-α), gamma interferon (IFN-γ) to evaluate the general disease resistance of the population, but in the preliminary test of the present invention, through the measurement of cytokines in a small sample size of piglets with different health status before and after w...

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Abstract

The invention relates to a Dongchuan pig general disease resistance comprehensive selection index selection breeding method. The method includes the steps of collecting precava blood when piglets are 28 days old, after serum is obtained, measuring the concentrations of interleukin 1 beta (IL-I beta), interleukin 4 (IL-4), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 10 (IL-10) and alpha interferon (IFN-alpha), then converting the six pieces of indicator data into standardized Z values, substituting the values into an established comprehensive selection index formula to calculate the comprehensive selection index value of each individual, and according to the values, determining individuals who have strong general disease resistance. The Dongchuan pig general disease resistance comprehensive selection index selection breeding method effectively overcomes the difficulty of how to select the optimum quantity index from numerous indexes, and finally achieves the purpose of scientifically evaluating the general disease resistance of Dongchuan pigs. The detection method is simple to operate, high in precision and capable of achieving automatic direct detection and plays a significant role in disease resistance breeding practice of the Dongchuan pigs.

Description

technical field [0001] The invention relates to the field of pig disease-resistant breeding, in particular to a selection breeding method for general disease resistance comprehensive selection index of Dongchuan pigs. Background technique [0002] With the popularization of intensive feeding and management methods, in the production of pig industry, the hazards of diseases can easily bring heavy losses to animal husbandry production. In the United States, swine diseases cost more than $1.5 billion annually. This huge economic loss is mainly due to pig deaths, reduced production efficiency, increased medical expenses, and product losses. Under stressful production conditions, selective pressure on economically important traits can also lead to increased disease incidence. Diseases can reduce the efficiency of selection and affect the genetic improvement of production traits. At present, the control measures for pig diseases mainly use vaccination and antibiotic drug treatm...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K67/02
CPCA01K67/02
Inventor 包文斌刘颖吴圣龙是英豪程洪青黄小国
Owner YANGZHOU UNIV
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