Selection Breeding Method of Comprehensive Selection Index for General Disease Resistance of Large White Pigs

Abstract

The invention relates to a large white pig general disease resistance comprehensive selection index selection breeding method. The method is to measure the concentrations of IL-1β, IL-4, IL-6, IL-8, IL-10, TGF-β, TNF-α and IFN-γ in piglets at the age of 30 days; In order to standardize the Z-score, the comprehensive selection index value of each individual was calculated by substituting the established comprehensive selection index formula, and the individual with strong disease resistance was determined according to the value. The invention well solves the difficult problem of how to select the optimal quantity index from many indexes, and finally achieves the purpose of scientifically evaluating the general disease resistance and immune response ability of Large White pigs. The detection method of the invention is simple to operate, has high accuracy, and can realize automatic direct detection. The invention will play a huge role in the practice of pig disease-resistant breeding.

Description

Technical field [0001] The invention relates to the field of pig disease-resistant breeding, in particular to a selective breeding method for establishing a comprehensive selection index for general disease resistance of large white pigs to screen individuals with high disease resistance. Background technique [0002] With the popularization of intensive feeding and management methods, in the production of pig industry, the hazards of diseases can easily cause major losses to animal husbandry production. In the United States, the annual cost of pig disease exceeds 1.5 billion US dollars. This huge economic loss is mainly caused by pig deaths, reduced production efficiency, increased medical costs, and product losses. Under stressful production conditions, the selective pressure imposed on important economic traits can also lead to an increase in the incidence of diseases. Disease will reduce the efficiency of selection and affect the genetic improvement of production traits. A...

AI Technical Summary

Problems solved by technology

But so far, there is no evaluation system for the general disease resistance of pigs, and it is impossible to comprehensively evaluate the individual immune response ability. This has become a bottleneck problem in the breeding practice of pigs to improve the general disease resistance. The establishment of pig immunity index, Systematic research on in vitro methods and their relationship with actual disease resistance has become an urgent task and the key to breeding pig breeds with general resistance

Images