Kit for monitoring biomarker of IgA nephropathy
A technology of biomarkers and kits, applied in the field of medical testing, can solve problems such as inappropriate monitoring of disease progression and complications
Inactive Publication Date: 2019-01-11
深圳慈海医院
View PDF0 Cites 4 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0197] In order to better explain the technical solutions of the present invention, the embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. The following examples are used to further illustrate the present invention, but should not be construed as fixing or limiting the present invention. Unless otherwise specified, the technical features used in the embodiments may be replaced with other technical features known in the art that have equivalent or similar functions or effects without departing from the inventive concept.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention provides a kit for monitoring or detecting a pathogenetic process and / or a therapeutic process of IgA nephropathy. The kit comprises a PCR primer for detecting a small RNA biomarker, wherein the biomarker is selected from miR-15a, miR-16, miR-21, miR-29a, miR-34a, miR-125b, miR-141, miR-148b, miR-155, miR-184, miR-192, miR-200a, miR-200b, miR-200c, miR-204, miR-205, miR-210, miR-301aand miR-429. The kit can be used for excellently detecting the therapeutic process.
Description
technical field [0001] The invention belongs to the field of medical detection and relates to a kit for discovering biomarkers for monitoring IgA nephropathy. Background technique [0002] IgA nephropathy (IgA nephropathy, IgAN) is the most common primary glomerulonephritis in the world. Although the prevalence of IgAN in the general population is low, its prevalence is high, especially in Asia, estimated at 30–40% in renal biopsies. Approximately 30-40% of IgAN patients will progress to end- (ERSD) within 20-30 years, making IgAN the leading cause of ERSD worldwide. However, the pathogenesis of IgAN remains unclear and available treatments only relieve symptoms and delay the need for dialysis and kidney transplantation. Among patients with IgAN, some respond well to treatment and maintain renal function for long periods of time, however, it is less understood that some patients are resistant to treatment and require dialysis more rapidly, and that mortality in IgAN patien...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6883C12N15/113
CPCC12Q1/6883C12Q2600/158C12Q2600/178
Inventor 何永成陈小波
Owner 深圳慈海医院