Novel multi-channel handheld SPR detector

Abstract

The invention discloses a novel multi-channel handheld SPR detector. The novel multi-channel handheld SPR detector comprises a casing; a light incidence assembly, alight reflection assembly and a light reception assembly are sequentially clamped in a light incidence assembly accommodating cavity, a light reflection assembly accommodating cavity and a light reception assembly capacity; a sensing chip comprises a substrate and a gold-plated glass piece; sensing chip guiderails are symmetrically arranged on the inner surfaces of the front and rear sides of the casing; sensing chip brackets are glidingly arranged on the sensing chip guiderails; sensing chips are arranged in the sensing chip brackets; and injection port sealing and connection devices and extraction port sealing and connection devices are respectively arranged at positions, corresponding to a plurality of sample storage grooves and sample recovery grooves, on the surface of the casing. The novel multi-channel handheld SPR detector is capable of directly extracting a plurality of liquid samples from a sample storage vessel at one time without dripping the liquid samples into a loading slot after taking the sensing chips in exposed environment, thereby preventing the liquid samples from being polluted and then improving the detection correctness.

Description

technical field [0001] The invention relates to a biological detection instrument, in particular to a novel multi-channel hand-held SPR detection instrument. Background technique [0002] Surface plasmon resonance (SPR) is a physical optical phenomenon. At the interface of two transparent media with different refractive index (such as glass and water), when a beam of light is incident from a medium with a high refractive index to a medium with a low refractive index, the light will be refracted and reflected. When the incident angle increases to a certain value, the refraction angle is equal to 90°, and the light is emitted along the direction tangent to the interface. The incident angle at this time is called the critical angle. If the incident angle exceeds the critical angle, the incident light will not enter another medium, but all will be reflected back into the incident medium, and total internal reflection will occur. [0003] In fact, although all incident light is...

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Problems solved by technology

[0006] In the above-mentioned patents, on the one hand, when adding the liquid sample to be tested, the sensor chip needs to be taken out, and the liquid sample to be tested is dropped into the sampling tank under the exposed environment, which is inconvenient to operate and will also cause contamination of the liquid sample to be tested.

At the same time, due to the actual work, it is often necessary to store the liquid sample to be tested, and then perform SPR detection. On the other hand, the existing handheld SPR detector can only perform SPR detection on one sample at a time, and the detection efficiency is low.

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