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A kind of contact lens material and its preparation method and contact lens

A contact lens, acrylic technology, used in glasses/goggles, instruments, optics, etc., to achieve the effect of improving service life, good biocompatibility, and high light transmittance

Active Publication Date: 2022-06-24
GUANGZHOU YUEQING REGENERATION MEDICINE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the inventor found in actual research that the light transmittance of the biocompatible optically transparent polymer material provided by this patent is only about 90%, which needs to be further improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 contact lens material

[0025] (1) adding porcine sclera into 1mol / L formic acid, dispersing for 20min, then filtering through a 100-micron filter to obtain an acidic collagen solution; wherein the weight ratio of porcine sclera and formic acid is 1:50;

[0026] (2) mixing the hydrophilic acrylic monomer with 1 mol / L formic acid in a weight ratio of 5:1, then adding it to the acidic collagen solution of equal weight, and dispersing for 20 min to obtain mixed solution 1;

[0027] (3) The hydrophilic acrylic monomer and the hydrophobic acrylic monomer are mixed in a weight ratio of 3:1 at 90° C. for 80 min to obtain a mixed solution 2;

[0028] (4) mixing mixed solution 1 and mixed solution 2, carrying out polymerization reaction under the action of γ-ray of 5.0Kgray to obtain described contact lens material;

[0029] The hydrophobic acrylic monomer is 4-methacryloyloxy-2-hydroxybenzophenone;

[0030] The hydrophilic acrylic monomer is sp...

Embodiment 2

[0031] The preparation of embodiment 2 contact lens material

[0032] (1) adding porcine sclera into 1mol / L formic acid, dispersing for 20min, then filtering through a 100-micron filter to obtain an acidic collagen solution; wherein the weight ratio of porcine sclera and formic acid is 1:40;

[0033] (2) mixing the hydrophilic acrylic monomer and 1 mol / L formic acid in a weight ratio of 4:1, then adding it to the acidic collagen solution of equal weight, and dispersing for 20 min to obtain mixed solution 1;

[0034] (3) The hydrophilic acrylic monomer and the hydrophobic acrylic monomer are 4:1 by weight, and mixed with 90° C. for 80 min to obtain mixed solution 2;

[0035] (4) mixing mixed solution 1 and mixed solution 2, and carrying out a polymerization reaction under the action of gamma rays of 4.0Kgray to obtain the contact lens material;

[0036] Described hydrophobic acrylic monomer is 3-benzoyl ethyl acrylate;

[0037] The hydrophilic acrylic monomer is specifically ...

Embodiment 3

[0038] The preparation of embodiment 3 contact lens material

[0039] (1) adding porcine sclera into 1 mol / L formic acid, dispersing for 20min, then filtering through a 100-micron filter to obtain an acidic collagen solution; wherein the weight ratio of porcine sclera and formic acid is 1:45;

[0040] (2) mixing the hydrophilic acrylic monomer with 1 mol / L formic acid in a weight ratio of 5:1, then adding it to the acidic collagen solution of equal weight, and dispersing for 20 min to obtain mixed solution 1;

[0041] (3) The hydrophilic acrylic monomer and the hydrophobic acrylic monomer are 4:1 by weight, and mixed with 90° C. for 80 min to obtain mixed solution 2;

[0042] (4) mixing mixed solution 1 and mixed solution 2, and carrying out a polymerization reaction under the action of γ-rays of 3.5Kgray to obtain the described contact lens material;

[0043] Described hydrophobic acrylic monomer is 3-allyl-4-hydroxyacetophenone;

[0044] The hydrophilic acrylic monomer is ...

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Abstract

The invention relates to the technical field of lens materials, and specifically discloses a contact lens material, a preparation method thereof and a contact lens. The preparation method of the contact lens material comprises the following steps: mixing an acidic collagen solution and a hydrophilic acrylic monomer to obtain a mixed liquid 1; mixing a hydrophilic acrylic monomer and a hydrophobic acrylic monomer to obtain a mixed solution 1; Solution 2; mixed solution 1 and mixed solution 2 are mixed to carry out polymerization reaction to obtain the contact lens material; the hydrophilic acrylic monomer is passed through 3-isopropenyl-α,α-dimethylbenzyl Polymerization of isocyanate with D-glucose polyethylene oxide. Compared with the prior art, the contact lens material of the invention has higher light transmittance. At the same time, the invisible material also has good biocompatibility, tensile strength and refractive index.

Description

technical field [0001] The invention relates to the technical field of eyeglass materials, in particular to a contact lens material, a preparation method thereof, and a contact lens. Background technique [0002] Contact lenses, also known as contact lenses, are lenses that are worn on the cornea of ​​the eye to correct vision or protect the eyes; according to the hardness of the material, it includes three types: rigid, semi-rigid, and soft. Common contact lens materials will absorb protein and other substances in aqueous humor and cause contact lens contamination, so they need to be cleaned every day, and at the same time, the service life of contact lenses is not long. For example, common contact lenses are divided into daily, monthly, quarterly, semi-annual and annual. [0003] Chinese patent CN1163627A discloses a collagen-based biocompatible optically transparent polymeric material and its manufacturing method; the method obtains a biological phase by polymerizing an ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08F289/00C08F220/30C08F220/28C08F212/14G02C7/04
CPCC08F289/00G02C7/049C08F220/302C08F212/26C08F220/283C08F212/24
Inventor 官习鹏
Owner GUANGZHOU YUEQING REGENERATION MEDICINE TECH CO LTD