3 results about "Contact lens material" patented technology

The application discloses a kind of hydrophilic rigid gas-permeable contact lens materials and its surface grafting modified preparation method, comprising the following steps: using the monomer containing isocyanate group or epoxy group and the copolymerization of silane monomer and methyl methacrylate to prepare rigid contact lens;The above-mentioned rigid contact lens is immersed into the solution containing hydrophilic macromolecule of hydroxyl or amino, and the covalent reaction of epoxy group and amino or isocyanate group and hydroxyl or amino is carried out at high temperature, and the hydrophilic macromolecule is grafted on the surface of lens;The present application is simple and easy to operate, and the product after grafting is stable, which can significantly improve the hydrophilicity of the lens without affecting the transparency of the lens.

This invention belongs to the field of contact lens materials technology, specifically relating to 3D-printed hydrogel materials, their preparation methods, and their application in the fabrication of smart contact lenses. The 3D-printed hydrogel material comprises the following raw material components: hydroxyethyl methacrylate, polyethylene glycol diacrylate, 3-(trimethoxysilyl)propyl methacrylate, Pluronic F-127, poly(3,4-ethylenedioxythiophene):poly(p-phenylene sulfonate), and a photoinitiator. The 3D-printed hydrogel material provided by this invention can be directly molded into a contact lens substrate through high-precision 3D printing, thus providing a core material basis for developing next-generation comfortable, precise, and mass-producible personalized smart intraocular pressure monitoring contact lenses. This invention also provides its preparation method. Applying the hydrogel material of this invention to 3D-printed contact lenses meets the requirements for mechanical performance and comfort in contact lenses.

This invention discloses a method for preparing a photothermal controlled-release hydrogel contact lens material. The method involves chemically bonding ganciclovir with hydroxypropyltrimethylammonium chloride chitosan, then adding methacrylic anhydride to introduce double bonds. The resulting product is used as a crosslinking agent to crosslink and copolymerize with hydroxyethyl methacrylate (MXene) nanosheets to prepare the hydrogel material. The prepared photothermal controlled-release hydrogel contact lens material can bond drugs to the polymer chains of the hydrogel contact lens for drug loading, avoiding drug loss due to tear rinsing, thereby improving drug storage stability. Furthermore, it can be modulated with near-infrared light to generate a photothermal effect, raising the hydrogel temperature and triggering the breakage of thermosensitive azo bonds, releasing the drug into the contact lens matrix. When the lens is worn, the drug can be slowly released from the contact lens into the eye, potentially making it a multifunctional contact lens material for treating eye diseases.