113 results about "Contact lens material" patented technology

A contact lens is provided that is capable of being worn by a user. The lens includes a contact lens body having an eye-engaging surface placeable against a surface of an eye and an outer surface. Microphobic features are provided in the lens for eliminating microbes from the eye-engaging surface. Preferably, these microphobic features are chosen from a group consisting of electrical charge inducing agents, magnetic field inducing agents, chemical agents and textural features. In another embodiment of the present invention, a contact lens is provided that can include a reservoir portion capable of holding a performance enhancement agent for enhancing the performance of the lens. The performance enhancement agent can include such thins as sealant solutions, protective agents, therapeutic agents, anti-microbial agents, medications and reduced size transparent portions. In other embodiments, a wide variety of designs, materials and substances are disclosed for use with contact lenses.

A copolymer useful as a rigid gas permeable contact lens material is the polymerization product of a monomeric mixture comprising a polysiloxane-containing urethane or urea prepolymer endcapped with polymerizable ethylenically unsaturated radicals.

A device and method for non-invasive real-time testing of blood sugar levels in a diabetic patient. Specifically, this invention is directed to an optical device comprising a contact lens having a glucose-sensing optical pattern imprinted, marked, coated or otherwise disposed on or incorporated within the contact lens. The indicator pattern is further comprised of a glucose-sensing coating containing a boronic acid derivative, which reacts in the presence of glucose to create a readable pattern, which can then be correlated to a pre-determined or pre-calibrated blood glucose level. A polarized light source is one method that may be used to read the indicator pattern. The invention is also directed to methods for quantifying blood glucose levels using the inventive optical device and manufacturing methods for disposing the glucose-sensing coating onto, or incorporating it into, the contact lens material.

A method for reducing the modulus of polymer silicone hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials.

Vinyl carbonate endcapped polysiloxanes containing a fluorinated side chain are useful as biomaterials, especially hydrogel biomaterials, including contact lens materials.

A contact lens is provided that is capable of being worn by a user. The lens includes a contact lens body having an eye-engaging surface placeable against a surface of an eye and an outer surface. Microphobic features are provided in the lens for eliminating microbes from the eye-engaging surface. Preferably, these microphobic features are chosen from a group consisting of electrical charge inducing agents, magnetic field inducing agents, chemical agents and textural features. In another embodiment of the present invention, a contact lens is provided that can include a reservoir portion capable of holding a performance enhancement agent for enhancing the performance of the lens. The performance enhancement agent can include such thins as sealant solutions, protective agents, therapeutic agents, anti-microbial agents, medications and reduced size transparent portions. In other embodiments, a wide variety of designs, materials and substances are disclosed for use with contact lenses.

A solution for soft, hydrogel contact lenses includes a polyether that is controllably released into an eye's tear film when the lens is worn. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved comfort, and / or reduced feeling of dryness from wearing contact lenses. The solution further includes a cationic polyelectrolyte.

A hybrid hard-soft contact lens is provided. Several embodiments of the invention include methods of coupling the hard and soft sections of the contact lens. Other embodiments of the invention include contact lens materials and coatings that increase oxygen transmission though the lens. Yet other embodiments of the invention are directed to cost-effective manufacturing methods of a hybrid hard-soft contact lens. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

The invention discloses a high oxygen-permeability fluorosilicone hydrogel contact lens material and a preparation method thereof. The high oxygen-permeability fluorosilicone hydrogel contact lens material is obtained by crosslinking copolymerization of a fluorine-containing polysilicone monomer with hydrophilic groups and ends capped by methacrylate and one or more hydrophilic monomers and siloxane monomers initiated by ultraviolet light or heat. The content of a fluorosilicone amphiphilic monomer in the mixed monomers is 20%-60%. The preparation method comprises the following steps: evenly mixing the fluorosilicone amphiphilic monomer, the hydrophilic monomers, the siloxane monomers, a crosslinking agent, an initiator and a diluent, injecting the mixture into a mold, initiating polymerization by ultraviolet irradiation or heat, then demolding, removing unreacted monomers or oligomers, and immersing in water to obtain hydrogel. The hydrogel material has high oxygen permeability, wettability, proteinosis resistance and the like, and is a corneal contact lens with excellent properties.

The invention relates to a drug-loaded contact lenses and a corresponding preparation method. The drug-loaded contact lenses are obtained firstly through UV-curing or heat-curing and then through drug-liquid immersion. The drug-loaded contact lenses can be particularly defined as a combination of a contact lenses material containing cyclodextrin and drug molecules and comprise the contact lenses formed by combining a crosslinked polymer hydrogel formed by copolymerizing mono-substituted cyclodextrin monomers, polymerization monomers and crosslinkers with one kind or a plurality of acetazolamide, methazolamide, puerarin or prostaglandin. The characteristic of forming inclusion compounds between the cyclodextrin molecules and drug molecules is adopted to increase the quantity of loaded drugs so as to reduce the stimulation to eyes by drugs and control the drug release speed for eye diseases of curing glaucoma, etc.

A radiation-proof light-filtering contact lens is characterized in that the weight ratio of each component of liquid material is as follows: 90 to 100 parts of hydroxyethyl methacrylate; 10 to 12 parts of ethenyl pyrrolidinone; 0.3 to 0.5 part of 2-propenoic acid, oxybis(2,1-ethanediyloxy-2,1-ethanediyl)ester; acrylic acid, diester with tetraethylene glycol; 0.15 to 0.2 part of 2,2'-dicyano-2,2'-azopropane azobisisbutyronitrile; 0.7 to 1 part of 4-[(E)-phenyldiazenyl]phenyl-2-methacrylate; and 3 parts of yellow pigment and dye for contact lenses. The contact lens has a good oxygen permeation coefficient, high moisture content, moderate hardness and fewer residues, and also has a good ultraviolet radiation protection effect and a good filtering effect on purple light and blue light.

A hybrid hard-soft contact lens is provided. Several embodiments of the invention include methods of coupling the hard and soft sections of the contact lens. Other embodiments of the invention include contact lens materials and coatings that increase oxygen transmission though the lens. Yet other embodiments of the invention are directed to cost-effective manufacturing methods of a hybrid hard-soft contact lens. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

Vinyl carbonate endcapped polysiloxanes containing a fluorinated side chain are useful as biomaterials, especially hydrogel biomaterials, including contact lens materials.

The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.

A hybrid hard-soft contact lens is provided. Several embodiments of the invention include methods of coupling the hard and soft sections of the contact lens. Other embodiments of the invention include contact lens materials and coatings that increase oxygen transmission though the lens. Yet other embodiments of the invention are directed to cost-effective manufacturing methods of a hybrid hard-soft contact lens. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

A soft contact lens comprises a module embedded in a soft contact lens material. The module comprises a hydrophobic material having channels formed therein, such that a surface tension of the aqueous solution within the channels inhibits release of therapeutic agent, such as a drug, through the one or more channels. The surface tension of the aqueous solution within the channel can inhibit diffusion of the therapeutic agent through the channel. The channels may comprise a cross-sectional area and optionally a length, such that therapeutic agent is released through the channels when pressure of the eyelid increases. In many embodiments, the contact lens is configured to inhibit release of the therapeutic agent when the contact lens comprises a free floating configuration, for example when stored in a contact lens solution, such that the storage time of the contact lens can be increased substantially.

Disclosed in this specification is a process for manufacturing a thermochromic contact lens. The process includes (1) selecting a photoinitiator that absorbs at a first wavelength and at least one thermochromic dye that displays substantial absorption at the first wavelength when the dye is at a first temperature and exhibits at least an 80% reduction in absorbance at the first wavelength at a second temperature, (2) maintaining the reaction mixture at the second temperature and (3) providing cure light that includes the first wavelength.

Disclosed are methods, materials and systems for producing contact lenses and contact lenses produced using said methods, materials and systems. According to some embodiments, a contact lens produced by said methods, materials and systems includes an extra-ocular indicator (“EOI”) adapted to alter in color upon removal of said lens from an eye. The EOI may be at least partially composed of a pigment adapted to become relatively more visible when the contact lens is outside an eye than when the contact lens is placed in an eye.

In accordance with the disclosure there is described herein a method of designing an anterior curve of a contact lens for the eye of a patient comprising the steps of providing a contact lens material having a posterior, a posterior curve having a predetermined asphericity, an anterior, an index of refraction and a center thickness; providing a geometry of a cornea, a distance power correction for the cornea and a near power correction for the cornea; determining a central distance power of the contact lens in air; calculating a central anterior radius of the contact lens using the posterior curve of the contact lens material, the index of refraction of the contact lens material, the center thickness of the contact lens material and the central distance power of the contact lens in air; calculating a center power of the contact lens on the eye of the patient using the index of refraction of tears at the posterior of the contact lens; and using an on-eye ray trace, said on-eye ray trace having a null lens compensation to create a targeted on-eye power profile.

This invention provides a mold for forming a contact lens comprising an overflow collector, which causes the overflow reactive mixture to be accumulated, and not to spread out as it would upon the typically flat surface of a prior art mold. This invention further provides a method of preventing the formation of contaminating pieces of overflow reactive mixture comprising the step of: preventing the overflow reactive mixture from spreading out on the mold.

Disclosed in this specification is a process for manufacturing a thermochromic contact lens. The process includes (1) selecting a photoinitiator that absorbs at a first wavelength and at least one thermochromic dye that displays substantial absorption at the first wavelength when the dye is at a first temperature and exhibits at least an 80% reduction in absorbance at the first wavelength at a second temperature, (2) maintaining the reaction mixture at the second temperature and (3) providing cure light that includes the first wavelength.

A hybrid hard-soft contact lens is provided. Several embodiments of the invention include methods of coupling the hard and soft sections of the contact lens. Other embodiments of the invention include contact lens materials and coatings that increase oxygen transmission though the lens. Yet other embodiments of the invention are directed to cost-effective manufacturing methods of a hybrid hard-soft contact lens. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

The invention relates to an anisotropic hydrogel and a method of producing the anisotropic hydrogel. The hydrogel exhibiting anisotropic properties is poly(vinyl alcohol) produced by preparing a solution of poly(vinyl alcohol) with a pre-selected concentration, thermally cycling the solution by freezing and thawing, stretching the hydrogel and thermally cycling the hydrogel at least one more time The anisotropic hydrogel is used for tissue replacement and reconstruction, bioagent entrapment and delivery, in preparing ultrasound or radiofrequency thermal therapy transmission pads and substitutes for ice bags, as denture base, in soft contact lens material, for wound covering bandages and phantoms for medical-related use.

The invention provides a hydrogel contact lens material and a preparation method thereof. The material comprises N-(1,3-dihydroxy-2-propyl) methyl acrylamide, acrylate monomer, acrylate crosslinker and initiating agent and is prepared through one-step ultraviolet-initiated or thermal-initiated polymerization. The preparation method comprises the steps as follows: the N-(1,3-dihydroxy-2-propyl) methyl acrylamide and acrylic acid or acrylamide monomer are uniformly mixed with the acrylate crosslinker and the initiating agent, or the N-(1,3-dihydroxy-2-propyl) methyl acrylamide and the acrylic acid or acrylamide monomer are uniformly mixed with the acrylate crosslinker, the initiating agent and diluent; then the mixture is poured into a mould to be subjected to one-step ultraviolet irradiation curing or heat curing in a baking oven; and the mould is opened and immersed in water or alcohol, so as to remove the diluent and unreacted monomer to obtain a hydrogel contact lens. The material has high water content and excellent water retention capacity.

A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.

Provided is a contact lens material. The material is characterized by comprising liquid raw materials, by weight, 90-100 parts of hydroxyethyl methylacrylate, 10-12 parts of n-vinyl pyrrolidone, 0.3-0.4 part of ethylene glycol dimethacrylate, 0.15-0.2 part of azodiisobutyronitrile and 0.7-1 part of yellow UV absorbents for contact lenses. The contact lenses have good oxygen permeation coefficient, good moisture content, moderate hardness and less residual components, and have functions of good ultraviolet protection and filtration of purple light and blue light.

The invention discloses a contact lens material, contact lenses, and a manufacturing method for contact lenses. The contact lens material comprises a siloxane polymer expressed by formula (I), wherein in the formula (I), R1, R2 and R3 are C1-C4 alkyl group, R4 is C1-C6 alkyl group, R5 is the residue obtained by removing NCO group from aliphatic or aromatic diisocyanate, R6 and R7 are alkylene group, n is an integer ranging from 4 to 80, and m is an integer ranging from 3 to 40; and the molecular weight of the siloxane polymer expressed by formula (I) is about 1000 to 10000. The contact lens material further comprises at least one hydrophilic monomer; a cross-linking agent or a siloxane polymer expressed by formula (II), wherein in the formula (II), p is an integer ranging from 4 to 80, and q is an integer ranging from 3 to 40; and an initiator.

A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.