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Cosmetic composition comprising an aqueous extract of rose fruit

A technology of cosmetic composition, water extract, applied in the field of eye contour area, capable of solving problems such as loss of radiance, nutritional imbalance

Pending Publication Date: 2021-02-02
LVMH RECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And the applicant determined that the activity and the fatigue of the vulnerable area lead to a micronutrient imbalance, causing loss of radiance and the presence of bags and dark circles under the eyes

Method used

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  • Cosmetic composition comprising an aqueous extract of rose fruit
  • Cosmetic composition comprising an aqueous extract of rose fruit
  • Cosmetic composition comprising an aqueous extract of rose fruit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0103] Therefore, according to a particular and preferred embodiment of the present invention, the aqueous extract of rose fruit is obtained by an extraction process comprising the following steps:

[0104] a) harvesting fresh rose fruit, optionally storing at -20°C,

[0105] b) grinding the fruit,

[0106] c) mixing 5 to 30%, especially 10%, of the plant material, preferably in acidified water (eg citric acid), at a temperature of especially 10 to 60°C, especially 30°C,

[0107] d) gradually increasing the temperature of the mixture, especially from 30 to 100°C, especially up to 50 to 70°C, or even up to 60°C,

[0108] e) extraction optionally with stirring,

[0109] f) liquid / solid separation,

[0110] g) optionally adding preservatives,

[0111] h) filtration, especially at 0.22 μm,

[0112] i) optionally packed, if necessary under nitrogen,

[0113] j) Optionally store at +4°C.

[0114] Rose fruit is selected from the group consisting of "green" fruit, "middle" frui...

Embodiment 1

[0214] Embodiment 1: the effect of the water extract of rose fruit on ATP synthesis

[0215] The effect of aqueous extracts of rose fruit on ATP synthesis in cultured normal human keratinocytes (KHN) was tested.

[0216] KHN was treated for 24 hours with:

[0217] - Aqueous extract of rose fruit: 0.3%.

[0218] - Positive control: Early from CODIF As energisant (Jania rubens extract rich in taurine and oligomeric furfuralan): 0.15%.

[0219] After 2 hours of treatment, use Biovision under the name ApoSENSOR TM The ATP Cell Viability Bioluminescence Assay Kit is a kit sold to detect and measure the level of ATP production expressed by bioluminescence according to the supplier's protocol and recommendations.

[0220] The test uses luciferase to catalyze the generation of light from ATP and luciferin according to the following reaction:

[0221] ATP+fluorescein+O2→oxyfluorescein+AMP+PPi+Co2+light.

[0222] The light generated, which is proportional to the amount of ATP ...

Embodiment 2

[0225] Example 2: Effect of water extract of rose fruit on enhancing barrier function (differentiation and epidermal cohesion)

[0226] Normal human keratinocytes (KHN) were cultured and then treated with an aqueous extract of rose fruit as described in the Materials and Methods section.

[0227] After KHN treatment, ADNc obtained after reverse transcription of the extracted total ARN was used to perform TaqMan low-density array (TLDA) study on the genes studied.

[0228] Aqueous extracts of rose rose were tested at 0.15% and 0.31% by weight of raw material (excipient water).

[0229] KHN culture

[0230] Normal human keratinocytes were derived from plastic surgery skin samples. Cells were cultured in complete Epilife medium at P5 at a seeding density of 50,000 cells per well in 12-well plates. At sub-confluence, cells were treated with rose extract at the doses described above for 24 hours.

[0231] TaqMan Low Density Array (TLDA) Technology

[0232] · Obtain the t...

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Abstract

The invention relates to a cosmetic composition for topical application to the skin, comprising, in a physiologically acceptable medium, at least an efficient quantity of at least one aqueous extractof rose fruit other than the fruit of the brier rose (i.e. Rosa canina), in particular an aqueous extract of rose fruit of the variety Evanrat or Rosa Jardin de Granville , as well as to the use thereof in particular to promote and / or enhance the supply of nutrients to the skin, reinforce the barrier function, and densify the extracellular matrix, especially in the area around the eyes.

Description

technical field [0001] The present invention relates to a method comprising at least one rose fruit (particularly Jardin de Cosmetic compositions of aqueous extracts of rose fruit) and uses thereof, especially for promoting and / or improving nutrient supply to the skin, enhancing barrier function and densifying the extracellular matrix, especially for the eye contour area. Background technique [0002] It is well known that the quality of nutrition is reflected in the health of the skin and that certain skin diseases are associated with deficiencies especially of certain micronutrients (Park K. Role of micronutrients in skin health and function. Biomol. Ther. 2015; 23; 207-217) . [0003] In fact, the skin's micronutrient balance can be affected by external and / or internal factors such as fatigue, stress, oxidation, UV exposure and / or cellular aging. [0004] In particular, observations in subjects sensitive to fatigue and stress include: [0005] - lower levels of hydrat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/04A61K8/06A61Q19/08A61Q19/00
CPCA61K8/042A61K8/06A61K8/97A61K8/9789A61K36/738A61Q19/08A61Q19/00A61K8/365A61K2800/87A61K2800/88A61Q17/00A61Q19/007A61Q19/02
Inventor V·佩谢J·弗兰基M·普诺尔
Owner LVMH RECH
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