Quick pre-freezing device for freeze-drying reagent
By designing a fast prefreezing device for lyophilized reagents, using cooling systems, rotation devices and temperature control systems, the problems of slow prefreezing speed and inaccurate temperature control in the prior art are solved, and a fast and uniform prefreezing effect is achieved, and the lyophilized efficiency and reagent quality are improved.
Patent Information
- Application Number
- CN202421051692.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-15
- Publication Date
- 2025-03-21
- Estimated Expiration
- 2034-05-15
AI Technical Summary
The existing lyophilized reagent prefreezing device has slow prefreezing speed and inaccurate temperature control, resulting in uneven prefreezing of reagents, affecting the efficiency and reagent quality of the lyophilized process.
A rapid prefreezing device for lyophilized reagents is designed, including a prefreezer, a prefreezer, a cooling system, a rotating device and a temperature control system. The cooling system achieves rapid cooling through the refrigerant circulation flow, the rotating device promotes the flow of cold air through the rotation of the prefreezing plate, and the temperature control system achieves precise temperature control through the temperature sensor and the controller.
The device ensures uniform temperature distribution, reduces energy consumption, reduces operating costs, and reduces environmental impact by speeding up the freezing speed, improving freezing efficiency, and shortening pre-freezing time.
Smart Images
Figure CN222651761U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of reagent freezing, in particular to a rapid pre-freezing device for freeze-dried reagents. Background Art
[0002] As we all know, in biotechnology and laboratory work, the pre-freezing process of lyophilized reagents is crucial for the subsequent lyophilization operation, and the pre-freezing efficiency directly affects the quality of the lyophilized reagents and the efficiency of the lyophilization process.
[0003] Existing pre-freezing devices usually have problems such as slow pre-freezing speed and inaccurate temperature control. The slow pre-freezing speed will cause uneven pre-freezing of the reagents, which will lead to uneven heat conduction and water sublimation during the freeze-drying process, causing stress or deformation inside the reagents, affecting their quality and stability, thereby prolonging the time of the entire freeze-drying process. The reduction in freeze-drying efficiency not only increases energy consumption, but may also lead to unsatisfactory reagent pre-freezing effects. Utility Model Content
[0004] 1. Technical issues to be solved
[0005] In view of the deficiencies of the prior art, the utility model provides a rapid pre-freezing device for freeze-dried reagents.
[0006] (II) Technical solution
[0007] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a rapid pre-freezing device for freeze-dried reagents, comprising a pre-freezing box, a pre-freezing chamber, a cooling system, a rotating device and a temperature control system, characterized in that: the pre-freezing chamber is arranged inside the pre-freezing box, the cooling system comprises a refrigerant, a cooling circulation pipe and a radiator, the cooling circulation pipe is arranged on the side wall of the pre-freezing chamber, the refrigerant circulates inside the cooling circulation pipe, a radiator is installed on the back wall of the pre-freezing box, the cooling circulation pipe is connected to the radiator, the rotating device comprises a rotating shaft, a mounting seat and a pre-freezing plate, the rotating shaft is vertically rotatably installed in the pre-freezing chamber, a plurality of groups of mounting seats are evenly distributed on the outer wall of the rotating shaft, a card slot is opened on one side of the pre-freezing plate, the card slot is adapted to the rotating shaft, the pre-freezing plate is adapted to the mounting seat, and a plurality of grooves for holding reagents are evenly arranged on the upper surface of the pre-freezing plate.
[0008] In order to facilitate the rotation of the rotating shaft, the utility model has an improvement in that the top end of the rotating shaft passes through the top wall of the pre-freezer and is equipped with a driven bevel gear, one side of the driven bevel gear is meshedly connected with an active bevel gear, and a driving motor is installed on the side of the active bevel gear away from the driven bevel gear.
[0009] In order to prevent the pre-freezing plate from detaching from the mounting seat during rotation, the utility model is improved in that two groups of guide strips are symmetrically installed on the top wall of the mounting seat, and two groups of guide grooves are symmetrically opened on the bottom wall of the pre-freezing plate, and the guide grooves are adapted to the guide strips.
[0010] In order to protect the driving motor, the utility model is improved in that a protection frame is installed on the outer surface of the driving motor, and a heat dissipation groove is opened on the top wall of the protection frame.
[0011] In order to ensure the sealing of the pre-freezing room, the utility model has the following improvements: a sealing door is installed on the front end face of the pre-freezing box, magnetic sealing strips are fixedly arranged on the four edges of the inner surface of the sealing door, and the sealing door is adsorbed to each other through the magnetic sealing strips.
[0012] In order to achieve precise control of the temperature of the pre-freezing chamber, the utility model is improved in that the temperature control system includes a temperature sensor and a controller, the temperature sensor is arranged on a side wall of the pre-freezing chamber, the controller is arranged on the outer wall of the sealing door, and the temperature sensor and the controller are electrically connected.
[0013] In order to quickly transfer the cold generated by the cooling medium, the utility model is improved in that the pre-freezing chamber is made of a high thermal conductivity material.
[0014] In order to reduce the heat exchange between the pre-freezing chamber and the external environment, the utility model is improved in that a heat insulating layer is arranged outside the pre-freezing chamber.
[0015] (III) Beneficial effects
[0016] Compared with the prior art, the utility model provides a rapid pre-freezing device for freeze-dried reagents, which has the following beneficial effects:
[0017] The rapid pre-freezing device for freeze-dried reagents uses a rotating device to drive a motor to drive an active bevel gear, which drives a rotating shaft, and the rotating shaft drives a mounting seat and a pre-freezing plate to rotate. The rotation of the pre-freezing plate can promote the flow of cold air in the pre-freezing chamber and increase the contact area between the cold air and the reagent, which helps to speed up the freezing speed, improve the freezing efficiency, shorten the pre-freezing time, and evenly distribute the cold air to all corners of the pre-freezing chamber, ensuring that the temperature distribution in the entire pre-freezing chamber is more even, and helps to reduce energy consumption in the pre-freezing process, which not only reduces operating costs but also helps to reduce impact on the environment.
[0018] The rapid pre-freezing device for freeze-dried reagents has a cooling system and a temperature control system, and the refrigerant circulates through a cooling circulation pipe, and the heat in the pre-freezing chamber is discharged through a radiator, so as to achieve rapid cooling of the pre-freezing chamber. The temperature sensor monitors the temperature in the pre-freezing chamber in real time, and the controller controls the operation of the cooling system according to the temperature signal, so that the temperature of the pre-freezing chamber is quickly reduced to the required pre-freezing temperature.
[0019] The rapid pre-freezing device for freeze-dried reagents can effectively reduce the cold loss in the pre-freezing chamber by providing a sealing door and a magnetic sealing strip. The sealing door is adsorbed to the pre-freezing box through the magnetic sealing strip, which can not only reduce energy consumption, but also improve the pre-freezing efficiency and shorten the pre-freezing time. The sealing door can also prevent the excessive loss of cold air. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 This is a schematic diagram of the three-dimensional structure of the utility model from a first angle;
[0021] Figure 2 This is a schematic diagram of the three-dimensional structure of the utility model from a second angle;
[0022] Figure 3 This is a schematic diagram of the internal structure of the pre-freezing chamber of the utility model;
[0023] Figure 4 It is a schematic diagram of the inverted three-dimensional structure of the pre-freezing plate of the utility model.
[0024] In the figure: 1. prefreezing box; 2. prefreezing chamber; 3. cooling circulation pipe; 4. radiator; 5. rotating shaft; 6. mounting seat; 7. prefreezing plate; 8. slot; 9. groove; 10. driven bevel gear; 11. driving bevel gear; 12. driving motor; 13. guide strip; 14. guide groove; 15. protective frame; 16. heat dissipation groove; 17. sealing door; 18. magnetic sealing strip; 19. temperature sensor; 20. controller; 21. insulation layer. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0026] See also Figure 1-4, a rapid pre-freezing device for freeze-dried reagents, comprising a pre-freezing box 1, a pre-freezing chamber 2, a cooling system, a rotating device and a temperature control system, characterized in that: the pre-freezing chamber 2 is arranged inside the pre-freezing box 1, the cooling system comprises a refrigerant, a cooling circulation pipe 3 and a radiator 4, the cooling circulation pipe 3 is arranged on the side wall of the pre-freezing chamber 2, the refrigerant circulates inside the cooling circulation pipe 3, the radiator 4 is installed on the back wall of the pre-freezing box 1, the cooling circulation pipe 3 is connected to the radiator 4, the rotating device comprises a rotating shaft 5, a mounting seat 6 and a pre-freezing plate 7, the rotating shaft 5 is vertically rotatably installed in the pre-freezing chamber 2, a plurality of groups of mounting seats 6 are evenly distributed on the outer wall of the rotating shaft 5, a card slot 8 is opened on one side of the pre-freezing plate 7, the card slot 8 is adapted to the rotating shaft 5, the pre-freezing plate 7 is adapted to the mounting seat 6, and a plurality of grooves 9 for holding reagents are evenly arranged on the upper surface of the pre-freezing plate 7. In this embodiment, when the reagent needs to be refrigerated, When performing rapid prefreezing, first, chemical reagent is dripped into each groove 9 on the prefreezing plate 7. Since the mounting seat 6 is provided with multiple groups, multiple prefreezing plates 7 can be prefreezed at the same time. Then, the card slot 8 is passed through the rotating shaft 5, so that the prefreezing plate 7 is installed on the mounting seat 6, and the cooling system is started. The refrigerant circulates through the cooling circulation pipe 3, and the heat in the prefreezing chamber 2 is discharged through the radiator 4, so that the prefreezing chamber 2 is quickly cooled. Then, the rotating device is started to rotate the rotating shaft 5. The rotating shaft 5 drives the mounting seat 6 and the prefreezing plate 7 installed on the mounting seat 6 to rotate, and drives the prefreezing plate 7 to rotate slowly in the prefreezing chamber 2. The rotation of the prefreezing plate 7 can promote the flow of cold air in the prefreezing chamber 2 and increase the contact area between the cold air and the reagent, which helps to speed up the freezing speed, improve the freezing efficiency, and shorten the prefreezing time. At the same time, rotating the prefreezing plate 7 can also help to evenly distribute the cold air to every corner of the prefreezing chamber 2, so as to ensure that the temperature distribution in the entire prefreezing chamber 2 is more uniform.
[0027] In actual use, it is further convenient to rotate the rotating shaft 5. In this embodiment, the top end of the rotating shaft 5 passes through the top wall of the pre-freezer 1 and is equipped with a driven bevel gear 10. One side of the driven bevel gear 10 is meshed and connected with an active bevel gear 11. A driving motor 12 is installed on the side of the active bevel gear 11 away from the driven bevel gear 10. When it is necessary to rotate the rotating shaft 5, the driving motor 12 is started, and the output end of the driving motor 12 drives the active bevel gear 11, the active bevel gear 11 drives the driven bevel gear 10, and the driven bevel gear 10 drives the rotating shaft 5, thereby starting the rotating device.
[0028] In actual use, in order to further prevent the pre-freezing plate 7 from detaching from the mounting seat 6 during rotation, in this embodiment, two groups of guide bars 13 are symmetrically installed on the top wall of the mounting seat 6, and two groups of guide grooves 14 are symmetrically opened on the bottom wall of the pre-freezing plate 7, and the guide grooves 14 are adapted to the guide bars 13. When the pre-freezing plate 7 is installed on the mounting seat 6, the guide grooves 14 at the bottom of the pre-freezing plate 7 are first aligned with the guide bars 13 on the mounting seat 6, so that the guide bars 13 are aligned and inserted with the guide grooves 14, so that the pre-freezing plate 7 is installed on the mounting seat 6, and the pre-freezing plate 7 is limited to prevent the pre-freezing plate 7 from detaching from the mounting seat 6 during rotation.
[0029] During actual use, the drive motor 12 is further protected. In this embodiment, a protection frame 15 is installed on the surface of the drive motor 12, and a heat dissipation groove 16 is opened on the top wall of the protection frame 15. The protection frame 15 can effectively prevent external objects, such as dust, moisture, and debris, from invading the interior of the drive motor 12, thereby protecting the electronic components and mechanical parts inside the drive motor 12 from damage. The heat dissipation groove 16 helps to accelerate the transfer and diffusion of heat, so that the heat in the protection frame 15 can be dissipated to the external environment more quickly, thereby improving the heat dissipation efficiency.
[0030] In actual use, in order to further ensure the sealing of the pre-freezing chamber 2, in this embodiment, a sealing door 17 is installed on the front end face of the pre-freezing box 1, and a magnetic sealing strip 18 is fixedly provided on the four edges of the inner surface of the sealing door 17. The sealing door 17 is adsorbed with the sealing door 17 by the magnetic sealing strip 18 to close the cabinet door. The sealing door 17 is adsorbed with the pre-freezing box 1 by the magnetic sealing strip 18, which can prevent the pre-freezing chamber 2 from exchanging gases with the outside world, thereby ensuring the sealing effect of the pre-freezing chamber 2.
[0031] In actual use, the temperature of the pre-freezing chamber 2 is further precisely controlled. In this embodiment, the temperature control system includes a temperature sensor 19 and a controller 20. The temperature sensor 19 is arranged on a side wall of the pre-freezing chamber 2, and the controller 20 is arranged on the outer wall of the sealing door 17. The temperature sensor 19 and the controller 20 are electrically connected. The temperature sensor 19 monitors the temperature in the pre-freezing chamber 2 in real time. The controller 20 controls the operation of the cooling system according to the temperature signal, so that the temperature of the pre-freezing chamber 2 is quickly reduced to the required pre-freezing temperature. When the pre-freezing is completed, the cooling system and the temperature control system are turned off, and the pre-frozen freeze-dried reagent is taken out for subsequent freeze-drying operations.
[0032] During actual use, the cold energy generated by the cooling medium can be further quickly transferred. In this embodiment, the pre-freezing chamber 2 is made of high thermal conductivity material, which can quickly transfer the cold energy generated by the cooling medium, ensuring that they reach the required freezing temperature in a short time.
[0033] In actual use, in order to further reduce the heat exchange between the pre-freezing chamber 2 and the external environment, in this embodiment, an insulating layer 21 is provided outside the pre-freezing chamber 2, and the insulating layer 21 is used to reduce the heat exchange between the pre-freezing chamber 2 and the external environment and improve the pre-freezing efficiency.
[0034] In order to explain in detail the possible application scenarios, technical principles, specific schemes that can be implemented, and the purposes and effects that can be achieved, the following is a detailed description of the specific embodiments listed in conjunction with the accompanying drawings. The embodiments described herein are only used to more clearly illustrate the technical solutions of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.
[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A rapid pre-freezing device for freeze-dried reagents, comprising a pre-freezing box (1), a pre-freezing chamber (2), a cooling system, a rotating device and a temperature control system, characterized in that: The prefreezing box (1) is provided with the prefreezing chamber (2) inside. The cooling system comprises a refrigerant, a cooling circulation pipe (3) and a radiator (4). The cooling circulation pipe (3) is arranged on the side wall of the prefreezing chamber (2). The refrigerant circulates in the cooling circulation pipe (3). The radiator (4) is installed on the back wall of the prefreezing box (1). The cooling circulation pipe (3) is connected to the radiator (4). The rotating device comprises a rotating shaft (5), a mounting seat (6) and a prefreezing plate (7). The rotating shaft (5) is vertically rotatably installed in the prefreezing chamber (2). A plurality of groups of mounting seats (6) are evenly distributed on the outer wall of the rotating shaft (5). A slot (8) is provided on one side of the prefreezing plate (7). The slot (8) is matched with the rotating shaft (5). The prefreezing plate (7) is matched with the mounting seat (6). A plurality of grooves (9) for containing reagents are evenly arranged on the upper surface of the prefreezing plate (7).
2. The rapid pre-freezing device for freeze-dried reagents according to claim 1, characterized in that: The top end of the rotating shaft (5) passes through the top wall of the pre-freezer (1) and is provided with a driven bevel gear (10); one side of the driven bevel gear (10) is meshedly connected with a driving bevel gear (11); and a driving motor (12) is provided on the side of the driving bevel gear (11) away from the driven bevel gear (10).
3. The rapid pre-freezing device for freeze-dried reagents according to claim 2, characterized in that: Two groups of guide strips (13) are symmetrically mounted on the top wall of the mounting seat (6), and two groups of guide grooves (14) are symmetrically opened on the bottom wall of the pre-freezing plate (7), wherein the guide grooves (14) are adapted to the guide strips (13).
4. The rapid pre-freezing device for freeze-dried reagents according to claim 3, characterized in that: A protection frame (15) is installed on the outer surface of the driving motor (12), and a heat dissipation groove (16) is provided on the top wall of the protection frame (15).
5. The rapid pre-freezing device for freeze-dried reagents according to claim 4, characterized in that: A sealing door (17) is installed on the front end face of the pre-freezing box (1), and magnetic sealing strips (18) are fixedly arranged on the four edges of the inner surface of the sealing door (17), and the sealing door (17) is adsorbed to each other through the magnetic sealing strips (18).
6. The rapid pre-freezing device for freeze-dried reagents according to claim 5, characterized in that: The temperature control system comprises a temperature sensor (19) and a controller (20); the temperature sensor (19) is arranged on a side wall of the pre-freezing chamber (2); the controller (20) is arranged on an outer wall of the sealing door (17); and the temperature sensor (19) and the controller (20) are electrically connected.
7. The rapid pre-freezing device for freeze-dried reagents according to claim 6, characterized in that: The pre-freezing chamber (2) is made of a high thermal conductivity material.
8. The rapid pre-freezing device for freeze-dried reagents according to claim 7, characterized in that: A heat insulating layer (21) is arranged outside the pre-freezing chamber (2).