A kind of chitosan composition for preventing and treating chemical liver injury and preparation method thereof

Abstract

The invention discloses a chitosan composition for prevention and treatment of chemical liver injury and a preparation method thereof. Main materials of chitosan, the root of kudzu vine, Poria, Ganoderma lucidum, medlar and gardenia are subjected to the medicinal material dry paste powder preparation, of chitosan preparation, mixing granulation and capsule filling and packing, so as to obtain the composition. The chitosan in the formula of the invention can promote the secretion of liver oxidase, activate and regenerate liver cells; the root of kudzu vine, Poria, Ganoderma lucidum, medlar and gardenia are Chinese herbal medicines used as both medicine and food, and have the effects of invigorating liver and kidney, clearing heat, removing dampness, promoting blood circulation and removing blood stasis; and the composition for prevention and treatment of chemical liver injury prepared from the above materials can achieve the effects of addressing both the symptoms and root cause and enhancing curative effect for chemical liver injury. The preparation method is simple, low in industrialized production cost, and easy for implementation, and has optimistic market outlook.

Description

technical field

[0001] The invention belongs to the field of medicine and health care, and in particular relates to a chitosan composition for preventing and treating chemical liver damage and a preparation method thereof. Background technique

[0002] Chemical liver injury is liver injury caused by chemical hepatotoxic substances, including alcohol, chemical poisons in the environment, and certain drugs. The liver is the largest and most important detoxification organ in the human body. It has a powerful defense and detoxification function against toxins from the outside and the body's own metabolism. In daily life, chemical substances will enter the liver through the gastrointestinal tract and blood circulation for transformation. Therefore, the liver is easily damaged by these chemical substances, causing different degrees of liver cell necrosis, fat deformation, liver cirrhosis and liver cancer, that is, causing chemical damage. liver damage.

[0003] In my country, al...

Examples

Embodiment 1

[0022] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0023] The mass percentages of the components in the main ingredients are as follows: 23% chitosan, 20% kudzu root, 19% poria cocos, 15% ganoderma lucidum, 13% medlar, and 10% gardenia.

[0024] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0025] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine 2 extracts, and filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into SWZ-700 double...

Embodiment 2

[0030] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0031] The mass percentages of each component in the main ingredients are as follows: 22% chitosan, 19% kudzu root, 18% poria cocos, 16% ganoderma lucidum, 14% medlar, and 11% gardenia.

[0032] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0033] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine the 2 extracts, filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into the SWZ-700 do...

Embodiment 3

[0038] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0039] The mass percentages of each component in the main ingredients are as follows: chitosan 24%, kudzu root 21%, poria cocos 20%, ganoderma lucidum 14%, wolfberry fruit 12%, gardenia 9%.

[0040] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0041] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine the two extracts, and filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into a SW...

technical field

[0001] The invention belongs to the field of medicine and health care, and in particular relates to a chitosan composition for preventing and treating chemical liver damage and a preparation method thereof. Background technique

[0002] Chemical liver injury is liver injury caused by chemical hepatotoxic substances, including alcohol, chemical poisons in the environment, and certain drugs. The liver is the largest and most important detoxification organ in the human body. It has a powerful defense and detoxification function against toxins from the outside and the body's own metabolism. In daily life, chemical substances will enter the liver through the gastrointestinal tract and blood circulation for transformation. Therefore, the liver is easily damaged by these chemical substances, causing different degrees of liver cell necrosis, fat deformation, liver cirrhosis and liver cancer, that is, causing chemical damage. liver damage.

[0003] In my country, al...

Examples

Embodiment 1

[0022] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0023] The mass percentages of the components in the main ingredients are as follows: 23% chitosan, 20% kudzu root, 19% poria cocos, 15% ganoderma lucidum, 13% medlar, and 10% gardenia.

[0024] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0025] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine 2 extracts, and filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into SWZ-700 double...

Embodiment 2

[0030] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0031] The mass percentages of each component in the main ingredients are as follows: 22% chitosan, 19% kudzu root, 18% poria cocos, 16% ganoderma lucidum, 14% medlar, and 11% gardenia.

[0032] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0033] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine the 2 extracts, filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into the SWZ-700 do...

Embodiment 3

[0038] A chitosan composition for preventing and treating chemical liver damage is prepared from chitosan, kudzu root, poria cocos, ganoderma lucidum, medlar and gardenia as main ingredients.

[0039] The mass percentages of each component in the main ingredients are as follows: chitosan 24%, kudzu root 21%, poria cocos 20%, ganoderma lucidum 14%, wolfberry fruit 12%, gardenia 9%.

[0040] The preparation method of the chitosan composition for preventing and treating chemical liver injury specifically comprises the following steps:

[0041] (1) Preparation of dry paste powder of medicinal materials: Pueraria root, Poria cocos, Ganoderma lucidum, medlar and gardenia that passed the quality standard inspection were put into a TQWV2A.O multifunctional extraction tank, and water 10 times the mass of the medicinal materials was added to extract twice. Each time for 1.5h, combine the two extracts, and filter with 200-mesh silk cloth to obtain the filtrate; put the filtrate into a SW...