A device for detecting flow performance of heart valve

Abstract

The present invention discloses a device for detecting the flow performance of heart valves, characterized in that it comprises a power module for simulating ventricles, a liquid capacity module for simulating atrial functions, a compliance module for simulating blood flow resistance, a mounting module for replaceable valves, a collection module, and an image acquisition module; the collection module is provided with a liquid tank for plugging in the power module, the liquid capacity module, the compliance module, and the mounting module, so that the power module, the liquid capacity module, the compliance module, and the mounting module are all plugged into the collection module; the power module, the mounting module, the compliance module, and the liquid capacity module are connected to each other by at least one silicone tube, so that the fluid flows through the power module, the mounting module, the compliance module, and the liquid capacity module; the mounting module is connected to the image acquisition module, and when the detection device starts to detect the valve, the image acquisition module collects the movement state of the valve in the entire pulsation cycle.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a device for detecting the flow performance of heart valves. Background Art

[0002] Heart valve disease is a common heart disease. With the extension of human life expectancy and the aging of the population, the incidence of this disease is increasing. Heart valve disease is irreversible and will only gradually worsen. Artificial heart valve replacement surgery is an effective method for treating severe heart valve disease. For high-risk Class III medical devices such as interventional valves that need to be implanted in the body for a long time, their safety and effectiveness must be fully evaluated before they are applied to the human body, and a corresponding risk / benefit analysis must be performed. The in vitro pulsating flow performance of the heart valve is an important indicator reflecting the safety and effectiveness of the valve.

[0003] Practice has proved that as long as the simulation experimental device is reasonably designed and can better meet the requirements similar to physiological conditions, the results of experiments on the simulation device can reflect the hemodynamic function of artificial heart valves. However, the artificial heart valve function test equipment independently developed in my country currently has great differences in the performance of pulsating flow simulation devices in different laboratories or research institutions due to the inconsistency in the design principles and methods, experimental conditions and experimental operation processes of the artificial heart valve pulsating flow simulation circulation device, which makes different laboratories or research institutions have different test results for the same valve, and even the same laboratory has different results in different experiments, resulting in the lack of objectivity and comparability of the experimental results. In addition, when simulating the shape of the ventricular drive curve and the change of the contraction time interval during the test, the opening or closing of the valve is not synchronized, and the opening angle of the bileaflet valve is also different. This information cannot be captured and recorded in real time, and it is impossible to objectively evaluate whether the test difference comes from the valve itself or the error caused by the test device.

[0004] In view of the above technical problems, it is necessary to improve them. Summary of the invention

[0005] The purpose of the present invention is to provide a device for detecting the flow performance of a heart valve in view of the defects of the prior art.

[0006] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0007] A device for detecting the flow performance of heart valves, comprising a power module for simulating ventricles, a liquid capacity module for simulating atrial functions, a compliance module for simulating blood flow resistance, a mounting module for replaceable valves, a collection module, and an image acquisition module; the collection module is provided with a liquid tank for plugging in the power module, the liquid capacity module, the compliance module, and the mounting module, so that the power module, the liquid capacity module, the compliance module, and the mounting module are all plugged into the collection module; the power module, the mounting module, the compliance module, and the liquid capacity module are connected to each other by at least one silicone tube, so that the fluid flows through the power module, the mounting module, the compliance module, and the liquid capacity module; the mounting module is connected to the image acquisition module, and when the detection device starts to detect the valve, the image acquisition module collects the movement state of the valve in the entire pulsation cycle.

[0008] Furthermore, it also includes an isolated heart module, which is connected to the power module, the liquid capacity module, and the compliance module through at least one silicone tube; a valve is provided in the middle of the silicone tube connected to the isolated heart module, and the valve is used to control the opening and closing of each channel.

[0009] Furthermore, the power module includes a motor and a pump module; the motor is connected to the pump module, and the motor is used to drive the pump module to simulate the pulsating waveform of ventricular contraction and relaxation movements.

[0010] Furthermore, the installation module of the replaceable valve includes a first installation module and a second installation module; the first installation module and the second installation module are respectively arranged on both sides of the power module; the first installation module and the second installation module are provided with a differential pressure sensor, a sensitive element, an isolation diaphragm, and a measuring diaphragm on both sides; the isolation diaphragm is arranged on both sides of the sensitive element, the sensitive element is connected to the measuring diaphragm, and the measuring diaphragm is connected to the differential pressure sensor; when the fluid flows through the isolation diaphragm and the filling liquid in the sensitive element is transmitted to both sides of the measuring diaphragm, the pressure of the area to be measured is measured by the differential pressure sensor.

[0011] Furthermore, the installation module of the replaceable valve has a buffer sealing ring arranged around the installation position of the replaceable valve to prevent paravalvular leakage during the detection process; the material of the buffer sealing ring is one or more of silicone, rubber, foam material, and latex.

[0012] Furthermore, the compliance module includes an aortic compliance module and an arteriole compliance module, and the aortic compliance module and the arteriole compliance module are connected; the aortic compliance module includes a first base and a first liquid storage tank connected to the first base; the arteriole compliance module includes a second base and a second liquid storage tank connected to the second base; the first base and the second base are both provided with a damper connected to the base, a flow meter sleeved in the damper, and a first temperature sensor arranged on the base; the damper is used to adjust the size of the simulated blood flow resistance; the flow meter is used to measure the flow change near the valve; the first temperature sensor is used to detect the temperature of the fluid; the top of the first liquid storage tank is closed and is provided with an exhaust valve, and the exhaust valve is used to adjust the air in the first liquid storage tank; the top of the second liquid storage tank is open.

[0013] Furthermore, the liquid capacity module includes a third base and a third liquid storage tank connected to the third base, and the third base is provided with a second temperature sensor and a heating rod; the second temperature sensor is used to detect the temperature of the fluid; and the heating rod is used for heating.

[0014] Furthermore, an oil drip tray is provided in the collection module; the oil drip tray is used to capture liquid leaked during the detection process.

[0015] Furthermore, a baffle is provided on one side of the power module.

[0016] Furthermore, the image acquisition module includes at least two high-speed cameras arranged in parallel and an image processor.

[0017] Compared with the prior art, the heart valve flow performance detection device of the present invention can simulate the real human physiological environment and adopt an image acquisition module to analyze the closing performance of the valve and the dynamic changes of the valve during the cardiac cycle through visualization technology, and evaluate the valve performance from multiple angles. In addition, the present invention can also be connected to an isolated animal heart and used in combination with ultrasound, endoscope and other monitoring equipment to simulate the surgical site, practice the release accuracy of the artificial heart valve, and more accurately evaluate the performance of the valve under the animal physiological environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 A schematic diagram of the structure of a heart valve flow performance detection device provided in embodiments 1 and 2;

[0019] Figure 2 A top view of a heart valve flow performance detection device provided in Example 1;

[0020] Figure 3 A schematic diagram of the structure of a first installation module provided in Example 1;

[0021] Figure 4A schematic diagram of the valve insert structure provided in Example 1;

[0022] Figure 5 A schematic diagram of the structure of the aortic compliance module provided in Example 1;

[0023] Figure 6 A schematic diagram of the structure of an image acquisition module provided in Example 1;

[0024] Figure 7 A schematic diagram of flow rate variation curves of the test valve and the control valve provided in Example 1;

[0025] Figure 8 A top view of a heart valve flow performance detection device provided in Example 2;

[0026] Fig. 9 It is a structural schematic diagram of a heart valve flow performance detection device provided in Example 2;

[0027] Among them: 100. Collection module; 200. Power module; 200B. Baffle; 300. First installation module; 301. Second installation module; 3011. Valve insert base; 3012. Valve insert; 3012a. Valve installation position; 3012b Buffer sealing ring; 3012c. Camera (high-speed camera); 3012d Light source; 3012f. Connecting line; 3012g. External fixed shell of valve insert; 3013. Interface; 302. Isolated heart module; 303. Pressure difference sensor; 400. Liquid capacity module; 510. Aortic compliance module; 501. First base; 502. Flow meter; 503. Damper; 520. Arteriolar compliance module; 600. Image acquisition module; 601. Image acquisition card; 602. Camera controller; 603. Computer. DETAILED DESCRIPTION

[0028] The following describes the embodiments of the present invention by specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the following embodiments and features in the embodiments can be combined with each other without conflict.

[0029] The purpose of the present invention is to provide a device for detecting the flow performance of heart valves in view of the defects of the prior art.

[0030] Embodiment 1:

[0031] like Figure 1-7As shown, a heart valve flow performance detection device of the present embodiment includes a power module 200 simulating ventricular function, a liquid capacity module 400 simulating atrial function, a compliance module simulating blood flow resistance, a mounting module for replaceable valves, a collection module 100, and an image acquisition module 600; the collection module 100 is provided with a liquid tank for plugging in the power module 200, the liquid capacity module 400, the compliance module, and the mounting module, so that the power module 200, the liquid capacity module 400, the compliance module, and the mounting module are all plugged into the collection module 100; the power module 200, the mounting module, the compliance module, and the liquid capacity module 400 are connected by at least one silicone tube, so that the fluid flows through the power module 200, the mounting module, the compliance module, and the liquid capacity module 400; the mounting module is connected to the image acquisition module 600, and when the detection device starts to detect the valve, the image acquisition module 600 collects the movement state of the valve in the entire pulsation cycle.

[0032] like Figure 2 As shown, the installation module includes a first installation module 300 and a second installation module 301. The first installation module 300 and the second installation module 301 are respectively arranged on both sides of the power module 200; the compliance module includes an aortic compliance module 510 and an arteriolar compliance module 520, one end of the aortic compliance module 510 is connected to the first installation module 300; the other end of the aortic compliance module 510 is connected to one end of the arteriolar compliance module 520, the other end of the arteriolar compliance module 520 is connected to one end of the liquid capacity module 400, the other end of the liquid capacity module 400 is connected to one end of the second installation module 301, the other end of the second installation module 301 is connected to one end of the power module 200, and the other end of the power module 200 is connected to the first installation module 300.

[0033] The power module 200 includes a motor and a pump module; the motor is connected to the pump module, and the motor is used to drive the pump module to simulate the pulsation waveform of ventricular contraction and diastole movement. In this embodiment, the pulsation of simulating diastole is realized by the motor, and the pulsating flow is generated by the movement of the motor to simulate the blood flow in the human body.

[0034] The first installation module 300 and the second installation module 301 are completely the same. This embodiment takes the first installation module 300 as an example for specific description. Figure 3 As shown, the first installation module 300 includes a valve insert base 3011 and a valve insert 3012 (the insert in this embodiment refers to a replaceable valve). Generally, the valve insert base 3011 is connected to the detection device, and the valve insert 3012 is replaceable. The base 3011 includes two communication interfaces 3013 for connecting to the silicone tube. The valve insert 3012 is as shown in FIG. Figure 4As shown, the valve insert 3012 includes an outer fixed housing 3012g of the valve insert, a valve installation position 3012a, a buffer sealing ring 3012b, a camera 3012c, a light source 3012d, and a connecting line 3012f; the buffer sealing ring 3012b is arranged around the valve installation position 3012a to prevent paravalvular leakage during the detection process, wherein the material of the buffer sealing ring 3012b is one or more of silicone, rubber, foaming material, and latex. The camera 3012c is arranged around the valve installation position 3012a, and there are multiple cameras 3012c. In this embodiment, 4 cameras are installed, and the camera 3012c is used to collect the image of the valve and judge the working state of the valve. The light source 3012d is arranged outside the valve installation position 3012a to provide a light source for the camera to prevent the light from being too dark during the camera acquisition process (the position where the light source is arranged can provide sufficient light source for the camera, and is not limited here). The outer fixing housing 3012g of the valve insert is arranged outside the valve installation position 3012a, the buffer sealing ring 3012b, the camera 3012c, and the light source 3012d, and is used to fix the internal components. The outer fixing housing 3012g of the valve insert can be made of acrylic to facilitate observation of the valve. The connecting line 3012f is arranged outside the housing 3012g, and is used to connect the imaging signal analysis device (i.e., the image acquisition module 600).

[0035] Both sides of the first installation module 300 and the second installation module 301 are also provided with a pressure difference sensor 303 (such as Figure 2 As shown), a sensitive element (δ element), an isolation diaphragm, and a measuring diaphragm; the isolation diaphragm is arranged on both sides of the sensitive element, the sensitive element is connected to the measuring diaphragm, and the measuring diaphragm is connected to the differential pressure sensor; when the fluid flows through the isolation diaphragm and the filling liquid in the sensitive element and is transmitted to both sides of the measuring diaphragm, the pressure of the area to be measured is measured by the differential pressure sensor. The area to be measured involved in this embodiment refers to the replaceable valve in the valve insert 3012.

[0036] The first mounting module 300 and the second mounting module 301 at both ends of the power module 200 must be in the same direction. Since the valve is a semi-permeable membrane, the first mounting module 300 and the second mounting module 301 must be in the same direction to form a pulsating flow. When the simulated blood flow direction is clockwise, the pulsation generated by the power module 200 passes through the first mounting module 300 to the aorta compliance module 510, then to the arteriolar compliance module 520, then passes through the second mounting module 301, and finally reaches the power module 200.

[0037] like Figure 5As shown, the aorta compliance module 510 includes a first base 501 and a first liquid storage tank connected to the first base 501; the arteriolar compliance module 520 includes a second base and a second liquid storage tank connected to the second base; the first base 501 and the second base are both provided with a damper connected to the base, a flow meter sleeved in the damper, and a first temperature sensor arranged on the base; this embodiment takes the first base 501 as an example for specific description, the first base 501 is provided with a damper 503 connected to the base (wherein two dampers are arranged on the base), a flow meter 502 sleeved in the damper 503, and a first temperature sensor 504 arranged on the base; wherein the damper 503 is used to adjust the size of the simulated blood flow resistance; the flow meter 502 is used to measure the flow change near the valve, and transmit the measured information to the control system (such as the host computer), so that the control system calculates and processes the obtained measured value to obtain the valve regurgitation ratio. The first temperature sensor 504 is used to detect the temperature of the fluid.

[0038] The difference between the aortic compliance module 510 and the arteriole compliance module 520 is that the top of the first liquid storage tank of the aortic compliance module 510 is closed and provided with an exhaust valve 505, wherein the exhaust valve is used to adjust the air in the first liquid storage tank; the top of the second liquid storage tank of the arteriole compliance module 520 is open. The first liquid storage tank of the aortic compliance module 510 stores water, air, blood, etc., and the second liquid storage tank of the arteriole compliance module 520 stores water, air, etc. The difference between the first liquid storage tank and the second liquid storage tank is that the first liquid storage tank also has a storage function. The aortic compliance module 510 and the arteriole compliance module 520 can adjust the compliance by adjusting the amount of stored air and water. In order to better and more conveniently adjust the gas, the gas volume, that is, the compliance of the aorta, a throttling exhaust valve 505 interface is left at the top of the closed cylindrical tube of the first liquid storage tank, thereby adjusting the compliance of the aorta. The arteriole acts as a damping effect of the aorta in the human body to reduce the pulsation amplitude of blood pressure.

[0039] In this embodiment, the aorta compliance module 510 and the arteriole compliance module 520 mainly simulate the damping in the aorta and arteriole and record the parameters involved. The main functions of the aorta compliance module 510 and the arteriole compliance module 520 are to respectively simulate the blood flow compliance of the human aorta and arteriole, simulate the blood flow resistance, and record the temperature pressure and other parameters in the blood flow through the differential pressure sensor 303. Since the compliance and resistance of the aorta and arteriole are different, two compliance modules are needed to simulate them separately.

[0040] When the simulated blood passes through the aorta compliance module 510 and the arteriole compliance module 520, the respective flow meters can be used to observe whether the required flow rate is met, and the respective dampers can be used to adjust the loss to a suitable state. The respective first temperature sensors can detect the current temperature, and the control system determines whether the heating device needs to be started through the data of the first temperature sensor. In order to achieve good results, there are generally two dampers connected in series to ensure that the flow rate near the valve and the liquid capacity module is in a suitable detection state.

[0041] The liquid capacity module includes a third base and a third liquid storage tank connected to the third base; the third liquid storage tank is used to store physiological saline; a second temperature sensor and a heating rod are provided on the third base; the second temperature sensor is used to detect the temperature of the fluid; the heating rod is used to heat, so that the simulated body fluid circulating in the system during the test is maintained in an environment of (37±0.1)℃.

[0042] An oil drip tray is provided in the collection module 100; the oil drip tray is used to capture the leaked liquid during the detection process, and to make corrections when calculating the valve performance index, thereby improving the test precision.

[0043] The image acquisition module 600 includes at least two high-speed cameras 3012c arranged in parallel and an image processor. The image processor includes an image acquisition card 601, a camera controller 602, and a computer 603. The high-speed camera 3012c in the image acquisition module 600 cooperates with the image processor to perform three-dimensional imaging analysis of image acquisition. A single high-speed camera 3012c can track the movement state of the valve and capture the instantaneous opening and closing state of the valve. The two high-speed cameras arranged in parallel are connected to the image acquisition card 601, the camera controller 602, and the computer 603. The software program can realize three-dimensional imaging, and the accurate information such as the opening angle and opening area of ​​the valve can be calculated. At the same time, the three-dimensional movement model of the valve under test can be simulated. The movement state and defects can be carefully and comprehensively observed through the three-dimensional model in the computer 603, and simulation modifications can be performed in real time, which is greatly beneficial to the testing and development of the valve. Preferably, the image acquisition module 600 can also be provided with any one or more combinations of a light source, a black and white camera, a wide-angle camera, and a telephoto camera arranged in parallel with the high-speed camera, wherein the light source adopts an LED cold light source or a more advanced attosecond light source, which can greatly improve the image acquisition quality, and the black and white camera cooperates with the high-speed camera to improve the image acquisition quality in dark light conditions; the fusion algorithm in the wide-angle camera and the telephoto camera can provide smooth, high-quality optical zoom and high-detail, low-noise image acquisition.

[0044] In this embodiment, an artificial aortic valve with a specification of 22 mm and a control valve are used for testing. The control valve is installed in the first installation module, and the power module, compliance module, and liquid capacity module are adjusted to generate pulsating pressure and flow waveforms under approximate physiological conditions. The following Table 1 shows the pressure, flow and other parameters determined by debugging in this implementation case, which can meet the requirements of ISO5840-2005 and GB12279-2009.

[0045]

[0046]

[0047] Table 1

[0048] After the adjustment is stable, the control valve and the test valve are measured in turn, and the average transvalvular pressure difference, regurgitation percentage, effective opening area and other parameters of the valve when the simulated cardiac output is 5L / min are calculated. At the same time, the image processing system is connected to monitor the closing performance of the valve and the dynamic changes of the valve in the cardiac cycle during the detection period. Table 2 shows the detection results of each valve pulsating flow in 3 consecutive cycles.

[0049]

[0050] Table 2

[0051] Test results: In the test data of the third cycle of the test valve, the transvalvular pressure difference and the regurgitation percentage showed large fluctuations, and the regurgitation percentage exceeded 10%. The flow curves of the test valve and the control valve were retrieved (such as Figure 7 As shown), it was found that the test valve had obvious regurgitation. Checking the valve images collected at the corresponding time, due to the effect of the buffer sealing ring next to the valve installation position, no paravalvular leakage occurred, but it was caused by valve incomplete closure.

[0052] Compared with the current general detection device, the buffer sealing device at the valve installation of the present invention can tightly clamp the valve, and paravalvular leakage caused by loose clamping will not occur. The current general device can only cover a PTFE gasket on the extension of its stent, and fix the valve on the instrument by clamping the gasket, but it is impossible to completely seal between the gasket and the valve stent, and there will inevitably be a gap, which is easy to cause paravalvular leakage during the test. Three control valves (22mm) were tested continuously with different devices, and the reflux percentage data were compared. As shown in Table 3, the present invention can avoid the influence of the valve regulation method on the test and better evaluate the performance of the valve itself.

[0053]

[0054] Table 3

[0055] Compared with the prior art, the heart valve flow performance detection device of this embodiment can simulate the real human physiological environment and adopt an image acquisition module to analyze the closing performance of the valve and the dynamic changes of the valve during the cardiac cycle through visualization technology, thereby evaluating the valve performance from multiple angles.

[0056] Embodiment 2

[0057] The difference between the heart valve flow performance detection device of this embodiment and the first embodiment is that:

[0058] like Figure 1 , 8 The detection device of the present embodiment shown also includes an isolated heart module 302, which is connected to the power module 200, the liquid capacity module 400, the aortic compliance module 510, and the arteriole compliance module 520 respectively through at least one silicone tube; a valve is provided in the middle of the silicone tube connected to the isolated heart module, and the valve is used to control the opening and closing of each channel.

[0059] Specifically, the isolated heart module 302 is connected to the power module 200 through a silicone tube, wherein a valve V4 is provided in the middle of the silicone tube; the isolated heart module 302 is connected to the aorta compliance module 510 through a silicone tube, wherein a valve V1 is provided in the middle of the silicone tube; the isolated heart module 302 is connected to the arteriolar compliance module 520 through a silicone tube, wherein a valve V2 is provided in the middle of the silicone tube; the isolated heart module 302 is connected to the liquid-soluble module 400 through a silicone tube, wherein a valve V3 is provided in the middle of the silicone tube;

[0060] In this embodiment, a baffle 200B is provided on one side of the power module 200 . The baffle 200B is disposed on the side where the power module 200 is connected to the first mounting module 300 , and is used to block the fluid from flowing through the first mounting module 300 .

[0061] like Fig. 9 As shown, the isolated heart module 302 of this embodiment is used to place a "pig heart". The isolated "pig heart" is placed in the isolated heart module 302, and the power module 200, the liquid capacity module 400, the aortic compliance module 510, and the arteriole compliance module 520 are connected; during simulation, the valve V3 is closed, and the valves V1, V2, and V4 are opened, so that the isolated heart module is not connected to the liquid capacity module, and the isolated heart module is connected to the power module, the aortic compliance module, and the arteriole compliance module. At this time, one side of the power module is sealed with a baffle. At this time, the fluid is divided into two paths, one path passes through the power module and then returns to the isolated heart module, and the other path flows into the aortic compliance module, then flows into the arteriole compliance module, and finally returns to the isolated heart module.

[0062] This embodiment uses simulated body fluid instead of blood, starts the power module, makes the isolated "pig heart" beat like a living body and monitors the test-related physiological parameters, implants an artificial aortic valve into the isolated "pig heart", uses an endoscope to directly observe the internal condition of the heart and monitor the entire process of instrument intervention and release, combines a pressure difference sensor, flow meter, endoscope and color Doppler ultrasound, and detects the aortic pressure, ventricular pressure, atrial pressure, forward flow, reflux flow and related parameters during the pulsation of the isolated heart, and monitors the internal structure of the heart.

[0063] Compared with the prior art, this embodiment can also be connected to an isolated animal heart and used in combination with monitoring equipment such as ultrasound and endoscopes to simulate the surgical scene, practice the accuracy of the release of artificial heart valves, and more accurately evaluate the performance of the valve under the animal physiological environment.

[0064] The specific embodiments described herein are merely examples of the spirit of the present invention. Those skilled in the art may make various modifications or additions to the specific embodiments described or replace them in similar ways, but they will not deviate from the spirit of the present invention or exceed the scope defined by the appended claims.

Claims

1. A heart valve flow performance detection device, characterized in that: It includes a power module for simulating ventricle, a liquid capacity module for simulating atrial function, a compliance module for simulating blood flow resistance, a mounting module for replaceable valves, a collection module, and an image acquisition module; the collection module is provided with a liquid tank for plugging in the power module, the liquid capacity module, the compliance module, and the mounting module, so that the power module, the liquid capacity module, the compliance module, and the mounting module are all plugged in the collection module; the power module, the mounting module, the compliance module, and the liquid capacity module are connected by at least one silicone tube, so that the fluid flows through the power module, the mounting module, the compliance module, and the liquid capacity module; the mounting module is connected to the image acquisition module, and when the detection device starts to detect the valve, the image acquisition module collects the movement state of the valve in the entire pulsation cycle; The collection module is provided with an oil drip tray, which is used to capture the liquid leaked during the detection process, and to correct it when calculating the valve performance index, thereby improving the test precision; The image acquisition module includes at least two high-speed cameras arranged in parallel and an image processor. Perform three-dimensional imaging analysis of image acquisition by the high-speed camera and the image processor to simulate a three-dimensional motion model of the valve under test, observe the motion state and defects of the valve through the three-dimensional motion model, and perform simulation modification of the three-dimensional motion model in real time; It also includes an isolated heart module, which is connected to the power module, the liquid capacity module, and the compliance module through at least one silicone tube; a valve is provided in the middle of the silicone tube connected to the isolated heart module, and the valve is used to control the opening and closing of each channel; The installation module of the replaceable valve includes a first installation module and a second installation module; the first installation module and the second installation module are respectively arranged on both sides of the power module; a pressure difference sensor, a sensitive element, an isolation diaphragm, and a measuring diaphragm are arranged on both sides of the first installation module and the second installation module; the isolation diaphragm is arranged on both sides of the sensitive element, the sensitive element is connected to the measuring diaphragm, and the measuring diaphragm is connected to the pressure difference sensor; when the fluid flows through the isolation diaphragm and the filling liquid in the sensitive element and is transmitted to both sides of the measuring diaphragm, the pressure of the area to be measured is measured by the pressure difference sensor; The compliance module includes an aortic compliance module and an arteriole compliance module, and the aortic compliance module and the arteriole compliance module are connected; the aortic compliance module includes a first base and a first liquid storage tank connected to the first base; the arteriole compliance module includes a second base and a second liquid storage tank connected to the second base; the first base and the second base are both provided with a damper connected to the base, a flow meter sleeved in the damper, and a first temperature sensor arranged on the base; the damper is used to adjust the size of the simulated blood flow resistance; the flow meter is used to measure the flow change near the valve; the first temperature sensor is used to detect the temperature of the fluid; the top of the first liquid storage tank is closed and provided with an exhaust valve, and the exhaust valve is used to adjust the air in the first liquid storage tank; The top of the second liquid storage tank is open; The liquid capacity module includes a third base and a third liquid storage tank connected to the third base. The third base is provided with a second temperature sensor and a heating rod; the second temperature sensor is used to detect the temperature of the fluid; and the heating rod is used for heating.

2. A heart valve flow performance detection device as claimed in claim 1, characterized in that: The power module includes a motor and a pump module; the motor is connected to the pump module, and the motor is used to drive the pump module to simulate the pulsating waveform of ventricular contraction and relaxation.

3. A heart valve flow performance detection device as claimed in claim 1, characterized in that: The installation module of the replaceable valve has a buffer sealing ring arranged around the installation position of the replaceable valve to prevent paravalvular leakage during the detection process; the material of the buffer sealing ring is one or more of silicone, rubber, foam material, and latex.

4. A heart valve flow performance detection device as claimed in claim 1, characterized in that: A baffle is provided on one side of the power module.

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