Bioengineering pharmaceutical raw material mixing device

Abstract

The invention discloses a bioengineering pharmaceutical raw material mixing device, and belongs to the technical field of raw material medicine processing, the device comprises a body, a grinding assembly and a working assembly, the working assembly comprises a working motor, a central rotating shaft and a stirring assembly, the grinding assembly comprises a material guide block and a working screen plate, and the working screen plate is provided with a plurality of screen holes; a grinding channel is formed between the lower end face of the material guide block and the upper end face of the working screen plate, a feeding port is formed in the body, and a material guide slope for guiding feed of the feeding port into the grinding channel is arranged on the material guide block. According to the invention, particles in entering powder can be ground, so that the mixing efficiency is improved; liquid flows to drive powder in a grinding channel to enter a stirring space below, so that powder residues on a material guide block and a working screen plate are reduced; particles which are not ground are blocked and collected by the waste tank and cannot enter the stirring space to influence the discharging quality; liquid in the body is circularly stirred up and down, so that full mixing of upper and lower layers of liquid and powder is facilitated.

Description

Technical Field

[0001] The invention belongs to the technical field of raw material medicine processing, and in particular relates to a bioengineering pharmaceutical raw material mixing device. Background Art

[0002] Biopharmaceutical raw materials are mainly natural biological materials. With the development of technology, purposefully artificial biological raw materials have become the main source of current biopharmaceutical raw materials. Such as animal raw materials obtained by immunization, microorganisms or other cell raw materials obtained by changing gene structure, etc. The characteristics of biological drugs are high pharmacological activity, low toxicity and side effects, and high nutritional value. The raw materials used for biopharmaceuticals need to be mixed during processing.

[0003] The existing drug processing process requires mixing of raw materials. Since the raw materials include liquid materials and powder materials, the powder materials are prone to contain some larger particles. During the mixing process, the larger particles in the powder materials need to be dissolved layer by layer, resulting in low mixing efficiency and too long mixing time. Some particles cannot be dissolved and discharged, affecting the quality of the mixed liquid. The mixing process of the existing mixing device adopts a stirring method that mostly rotates the stirring rod horizontally. It may be difficult for the upper drug to fully move to the lower part, and the drug at the same height cannot be fully mixed with the drugs at other heights, resulting in unsatisfactory effect of the drug mixing process. Summary of the invention

[0004] In view of the above problems existing in the prior art, the technical problem to be solved by the present invention is to provide a bioengineering pharmaceutical raw material mixing device to improve the mixing efficiency of powder and liquid.

[0005] Technical solution: In order to solve the above technical problems, the technical solution adopted by the present invention is as follows:

[0006] A bioengineering pharmaceutical raw material mixing device comprises a main body and a grinding component and a working component arranged in the main body, the working component comprises a working motor, a central rotating shaft connected to the working motor and a stirring component connected to the central rotating shaft, the grinding component comprises a material guide block arranged in the main body and a working mesh plate connected to the central rotating shaft and corresponding to the material guide block, the working mesh plate is provided with a plurality of sieve holes, a grinding channel is formed between the lower end surface of the material guide block and the upper end surface of the working mesh plate, the main body is provided with a feed port, and the material guide block is provided with a material guide slope for guiding the feed from the feed port into the grinding channel.

[0007] Preferably, the working mesh plate is in a cone shape, and the height of the grinding channel gradually decreases from the middle to the surrounding areas.

[0008] Preferably, an annular waste trough is provided on the inner wall of the main body, and the materials discharged from the periphery of the grinding channel enter the waste trough.

[0009] Preferably, the stirring assembly includes two mounting plates symmetrically arranged up and down, and a first rotating shaft and a partition cylinder arranged between the two mounting plates, a first gear is provided at one end of the first rotating shaft, a first annular tooth groove corresponding to the first gear is provided in the main body, and a plurality of first stirring blades are provided on the first rotating shaft, and when the central rotating shaft drives the stirring assembly to rotate, the first gear rolls on the first annular tooth groove to drive the first rotating shaft to rotate.

[0010] Preferably, a second horizontally arranged rotating shaft is connected to the mounting plate, and a second gear is connected to one end of the second rotating shaft close to the inner wall of the main body, a limiting ring is provided on the inner wall of the main body, a second annular tooth groove corresponding to the second gear is provided on the limiting ring, and a plurality of second stirring blades are provided on the second rotating shaft, and when the central rotating shaft drives the stirring assembly to rotate, the second gear rolls on the second annular tooth groove to drive the second rotating shaft to rotate.

[0011] Preferably, a hollow box is connected to the mounting plate, the other end of the second rotating shaft is located in the hollow box and is connected to the first bevel gear, a third rotating shaft is rotatably connected between the two hollow boxes, both ends of the third rotating shaft are respectively located in a hollow box, and both ends of the third rotating shaft are respectively provided with a second bevel gear corresponding to the first bevel gear, and a plurality of third stirring blades are provided on the third rotating shaft, and when the second rotating shaft rotates, the third rotating shaft is driven to rotate by the second bevel gear.

[0012] Preferably, the plurality of third stirring blades are located in the partition tube, and when the third rotating shaft drives the third stirring blades to rotate, the liquid in the partition tube is driven to move upward.

[0013] Preferably, a plurality of the second rotating axes are symmetrically arranged, and a plurality of the first rotating axes are symmetrically arranged.

[0014] Beneficial effects: Compared with the prior art, the present invention has the following advantages:

[0015] 1. By setting up the grinding component, the particles in the incoming powder can be ground, the contact area between the powder and the liquid can be increased, and the mixing efficiency can be accelerated;

[0016] 2. A grinding channel is formed between the working mesh plate and the guide block, and grinding can be carried out by the drive of the working motor. The working mesh plate is provided with sieve holes to facilitate the passage of liquid and powder. The flow of liquid drives the powder in the grinding channel into the stirring space below, reducing the residual powder on the guide block and the working mesh plate;

[0017] 3. A waste tank corresponding to the grinding channel is provided. The unground particles are blocked and collected by the waste tank and will not enter the stirring space to affect the discharge quality. When the liquid passes through the waste tank, it can take away the fine powder in the waste tank and dissolve the large particles, which is conducive to the decomposition of the large particles. When the liquid in the stirring space rotates, it will also enter the waste tank from the second through hole to further decompose the large particles.

[0018] 4. The body is equipped with a stirring assembly connected to the central rotating shaft, which can stir the liquid in the body in an upward and downward cycle, which is conducive to the full mixing of the upper and lower layers of liquid and powder;

[0019] 5. A first rotating shaft and a first stirring blade are set. When the working motor drives the stirring component to rotate, the first gear and the corresponding first annular tooth groove can drive the first rotating shaft to rotate, so that the first stirring blade can drive the liquid downward; a second rotating shaft and a third rotating shaft are set. When the working motor drives the stirring component to rotate, the second gear and the corresponding second annular tooth groove can drive the second rotating shaft to rotate. When the second rotating shaft rotates, the third rotating shaft can be driven to rotate through the first bevel gear and the second bevel gear. The third stirring blade on the third rotating shaft drives the liquid in the partition cylinder upward for circulating stirring. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present invention;

[0021] Figure 2 is a schematic diagram of the structure of the stirring assembly of the embodiment;

[0022] Figure 3 is a schematic diagram of the three-dimensional structure of the stirring assembly of the embodiment;

[0023] Figure 4 is a schematic diagram of a top view of the structure of a stirring assembly of an embodiment;

[0024] Figure 5 Schematic diagram of the waste tank structure of the embodiment. DETAILED DESCRIPTION

[0025] The present invention is further illustrated below in conjunction with specific examples. The examples are implemented based on the technical solutions of the present invention. It should be understood that these examples are only used to illustrate the present invention and are not used to limit the scope of the present invention.

[0026] like Figure 1 and Figure 2As shown, a bioengineering pharmaceutical raw material mixing device includes a body 6, a grinding assembly and a working assembly. The body 6 is a cylindrical tank body. The grinding assembly and the working assembly are arranged in the body 6. The working assembly includes a working motor 11, a central rotating shaft 13 and a stirring assembly. The working motor 11 adopts an existing reduction motor and is arranged in the middle position of the outer top of the body 6. The central rotating shaft 13 is connected to the working motor 11 and extends downward into the body 6. The stirring assembly is connected to the lower end of the central rotating shaft 13. The grinding assembly includes a guide block 2 and a working mesh plate 3. The guide block 2 is an annular block. The outer circumferential wall of the guide block 2 is connected to the inner wall of the body 6. A central hole is arranged in the middle of the guide block 2. The thickness of the guide block 2 gradually decreases from the surrounding to the middle. The cross section of the guide block 2 is two symmetrical isosceles trapezoids. The working mesh plate 3 is arranged below the guide block 2. The working mesh plate 3 is in a cone shape. The central rotating shaft 13 passes through the center of the working mesh plate 3 and is connected to the working mesh plate 3. The working mesh plate 3 is provided with a plurality of sieve holes to facilitate the passage of liquid materials and powder materials smaller than the sieve hole diameter. After passing through, the liquid and powder materials enter the stirring space below. A grinding channel is formed between the lower end surface of the guide block 2 and the upper end surface of the working mesh plate 3. The upper end surface of the guide block 2 forms a guide slope. A feed port 12 is provided on the top wall of the body 6. A guide cavity 1 is formed between the upper end surface of the guide block 2 and the inner top wall of the body 6. The guide cavity 1 is connected with the grinding channel through the central hole of the guide block 2. Liquid materials and feed materials containing large particles of powder materials enter the guide cavity from the feed port 12 and slide down along the guide slope. The guide slope guides the feed into the grinding channel from the center hole, and the height of the grinding channel gradually decreases from the middle to the surrounding areas. During operation, the working motor 11 drives the working mesh plate 3 to rotate through the central shaft 13, and the upper end surface of the working mesh plate 3 and the lower end surface of the guide block 2 form a relative movement to grind large particles in the powder. Since the height of the grinding channel becomes smaller and smaller from the center to the surrounding areas, the large particles are ground into small particles that can pass through the sieve holes. In order to better grind the particles, a plurality of first grinding blocks are provided on the upper end surface of the working mesh plate 3, and a plurality of second grinding blocks corresponding to the first grinding blocks are provided on the lower end surface of the guide block 2. The first grinding blocks and the second grinding blocks protrude into the grinding channel, and the feed can be better ground with the cooperation of the first grinding blocks and the second grinding blocks.

[0027] like Figure 1 and Figure 5As shown, an annular waste trough 4 is provided on the inner wall of the body 6, and the position of the waste trough 4 corresponds to the lowest position around the grinding channel. The cross-section of the waste trough 4 is U-shaped, and a accommodating cavity is provided on the waste trough 4. The lowest outlet of the grinding channel is located above the waste trough 4. After the granular material is ground, the unground large particles enter the accommodating cavity of the waste trough 4 through the connecting channel under the action of gravity and centrifugal force. A plurality of second through holes are provided at the bottom of the waste trough 4. After the liquid enters from the feed port 12 and slides down onto the working mesh plate 3, the ground powder on the working mesh plate 3 can be brought to the bottom through the sieve holes. When the liquid slides down into the waste trough 4, the fine powder in the waste trough 4 can be brought to the bottom through the second through holes, and the unground large particles in the accommodating cavity of the waste trough 4 are flushed. On the one hand, the powder on the surface of the large particles is taken away, and on the other hand, the large particles are dissolved, which is beneficial to the decomposition of the large particles.

[0028] like Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, the stirring assembly is located below the working mesh plate 3, and the stirring assembly is used to stir the liquid and powder in the stirring space of the body 6. The stirring assembly includes two mounting plates 29, four first rotating shafts 16 and a partition cylinder 18. The two mounting plates 29 are symmetrically arranged up and down, and the mounting plates 29 are in a cross shape. The center of the upper mounting plate 29 is connected to the lower end of the central rotating shaft 13, and the lower mounting plate 29 is close to the inner bottom wall of the body 6. A second central shaft is provided at the center of the inner bottom wall of the body 6. The center of the lower mounting plate 29 is rotatably connected to the second central shaft. The four first rotating shafts 16 are symmetrically arranged between the two mounting plates 29. The upper end of the first rotating shaft 16 is rotatably connected to the upper mounting plate 29, and the lower end of the first rotating shaft 16 is rotatably connected to the lower mounting plate 29. The upper end of the first rotating shaft 16 passes through the upper mounting plate 29 and A first gear 15 is connected, and a first annular tooth groove 8 corresponding to the first gear 15 is provided in the body 6. The first annular tooth groove 8 is arranged on the annular inner wall of the waste tank 4 (it can also be arranged on the inner wall of the body 6). When the central shaft 13 drives the stirring assembly to rotate, the central shaft 13 drives the mounting plate 29 to rotate in the body 6, and the first gear 15 rolls along the first annular tooth groove 8 to drive the first shaft 16 to rotate around its axis. A plurality of first stirring blades 17 are arranged on the first shaft 16, and two symmetrically arranged first stirring blades 17 form a group. The first shaft 16 is provided with multiple groups of first stirring blades 17 from top to bottom, and when the first stirring blades 17 rotate, the liquid is driven to move downward. A partition tube 18 is arranged between the two mounting plates 29. The partition tube 18 is in the shape of a hollow cylinder with upper and lower openings. The partition tube 18 is arranged concentrically with the body 6. The upper end of the partition tube 18 is connected to the upper mounting plate 29 through two first fixing rods 14, and the lower end of the partition tube 18 is connected to the lower mounting plate 29 through two first fixing rods 14.

[0029] like Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, a transversely arranged second rotating shaft 22 is connected to the mounting plate 29, eight second rotating shafts 22 are arranged between two mounting plates 29 and four second rotating shafts 22 form a group, and there are two groups in total. The two groups of second rotating shafts 22 are symmetrically arranged up and down, the upper group of second rotating shafts 22 is located above the partition tube 18, and the lower group of second rotating shafts 22 is located below the partition tube 18. Four second fixing rods 25 are arranged on the upper mounting plate 29, and a bearing seat 21 is arranged on the second fixing rod 25. The upper group of second rotating shafts 22 is rotatably connected to the second fixing rod 25 through the bearing seat 21, and the four second rotating shafts 22 are symmetrically arranged; four second fixing rods 25 are also arranged on the lower mounting plate 29, and a bearing seat 21 is arranged on the second fixing rod 25. The lower group of second rotating shafts 22 is rotatably connected to the second fixing rod 25 through the bearing seat 21, and the four second rotating shafts 22 are symmetrically arranged. A second gear 20 is connected to one end close to the inner wall of the main body 6, and the second gear 20 is arranged vertically. A limiting ring 5 is provided on the inner wall of the main body 6. The position of the limiting ring 5 corresponds to the position of the second gear 20 and is located above the second gear 20. A second annular tooth groove 51 corresponding to the second gear 20 is provided on the lower end surface of the limiting ring 5. When the central rotating shaft 13 drives the stirring assembly to rotate, the central rotating shaft 13 drives the mounting plate 29 to rotate, and the mounting plate 29 drives the second rotating shaft 22 to rotate around the central rotating shaft 13. The second gear 20 rolls on the second annular tooth groove 51, thereby driving the second rotating shaft 22 to rotate around its axis. A plurality of second stirring blades 23 are provided on the second rotating shaft 22, and two second stirring blades 23 form a group. Two groups of second stirring blades 23 are provided on each second rotating shaft 22. When the second rotating shaft 22 drives the second stirring blade 23 to rotate, the second stirring blade 23 stirs the liquid in the main body 6.

[0030] like Figure 1 and Figure 2A hollow box 24 is connected to the center of each mounting plate 29. The upper hollow box 24 is connected to the center of the lower end surface of the upper mounting plate 29, and the lower hollow box 24 is connected to the center of the upper end surface of the lower mounting plate 29. Each hollow box 24 corresponds to a group of second rotating shafts 22. The end of the second rotating shaft 22 away from the inner wall of the body 6 is located in the corresponding hollow box 24 and is connected to the first bevel gear 26. When the second rotating shaft 22 rotates around its axis, it drives the first bevel gear 26 to rotate. A third rotating shaft 28 is rotatably connected between the two hollow boxes 24. The third rotating shaft 28 is located in the partition tube. 18, the upper end of the third rotating shaft 28 is located in an upper hollow box 24, and the upper end is connected to the second bevel gear 27, and the lower end of the third rotating shaft 28 is located in a lower hollow box 24, and the lower end is connected to the second bevel gear 27, and the second bevel gear 27 corresponds to the first bevel gear 26. When the first bevel gear 26 in the hollow box 24 rotates, it drives the corresponding second bevel gear 27 to rotate, thereby driving the third rotating shaft 28 to rotate around its axis. When the upper and lower groups of second rotating shafts 22 rotate by themselves, they act on the second bevel gear 27 together, and the third rotating shaft 28 is driven to rotate by the upper and lower second bevel gears 27, which has good stability. A plurality of third stirring blades 19 are provided on the third rotating shaft 28, and each four third stirring blades 19 form a group. The third rotating shaft 28 is provided with a plurality of groups of third stirring blades 19 at equal intervals from top to bottom. When the third rotating shaft 28 rotates, it drives the third stirring blades 19 to rotate. When the third stirring blades 19 rotate, they drive the liquid in the partition tube 18 to move upward, and cooperate with the first stirring blades 17 outside the partition tube 18 to drive the liquid downward, thereby completing the up and down circulation stirring of the liquid in the main body 6.

[0031] like Figure 1 As shown, a discharge port 7 is provided on the bottom side of the body 6 , and the mixed liquid mixture is discharged from the discharge port 7 .

[0032] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A bioengineering pharmaceutical raw material mixing device, characterized in that: The invention comprises a main body (6) and a grinding component and a working component arranged in the main body (6), wherein the working component comprises a working motor (11), a central rotating shaft (13) connected to the working motor (11), and a stirring component connected to the central rotating shaft (13); the grinding component comprises a material guide block (2) arranged in the main body (6) and a working mesh plate (3) connected to the central rotating shaft (13) and corresponding to the material guide block (2); the working mesh plate (3) is provided with a plurality of sieve holes, and a grinding channel is formed between the lower end surface of the material guide block (2) and the upper end surface of the working mesh plate (3); the main body (6) is provided with a material feed port (12), and the material guide block (2) is provided with a material guide slope for guiding the material from the material feed port (12) to enter the grinding channel.

2. The bioengineering pharmaceutical raw material mixing device according to claim 1, characterized in that: The working mesh plate (3) is in a cone shape, and the height of the grinding channel gradually decreases from the middle to the surrounding areas.

3. The bioengineering pharmaceutical raw material mixing device according to claim 2, characterized in that: An annular waste groove (4) is provided on the inner wall of the main body (6), and the material discharged from the periphery of the grinding channel enters the waste groove (4).

4. The bioengineering pharmaceutical raw material mixing device according to claim 1, characterized in that: The stirring assembly comprises two mounting plates (29) symmetrically arranged in an upper and lower direction, and a first rotating shaft (16) and a partition cylinder (18) arranged between the two mounting plates (29); a first gear (15) is arranged at one end of the first rotating shaft (16); a first annular tooth groove (8) corresponding to the first gear (15) is arranged in the body (6); a plurality of first stirring blades (17) are arranged on the first rotating shaft (16); when the central rotating shaft (13) drives the stirring assembly to rotate, the first gear (15) rolls on the first annular tooth groove (8) to drive the first rotating shaft (16) to rotate.

5. The bioengineering pharmaceutical raw material mixing device according to claim 4, characterized in that: The mounting plate (29) is connected to a transversely arranged second rotating shaft (22); one end of the second rotating shaft (22) close to the inner wall of the body (6) is connected to a second gear (20); a limiting ring (5) is provided on the inner wall of the body (6); a second annular tooth groove (51) corresponding to the second gear (20) is provided on the limiting ring (5); a plurality of second stirring blades (23) are provided on the second rotating shaft (22); when the central rotating shaft (13) drives the stirring assembly to rotate, the second gear (20) rolls on the second annular tooth groove (51) to drive the second rotating shaft (22) to rotate.

6. The bioengineering pharmaceutical raw material mixing device according to claim 5, characterized in that: The mounting plate (29) is connected to a hollow box (24); the other end of the second rotating shaft (22) is located in the hollow box (24) and is connected to a first bevel gear (26); a third rotating shaft (28) is rotatably connected between the two hollow boxes (24); two ends of the third rotating shaft (28) are respectively located in one hollow box (24); two ends of the third rotating shaft (28) are respectively provided with a second bevel gear (27) corresponding to the first bevel gear (26); a plurality of third stirring blades (19) are provided on the third rotating shaft (28); when the second rotating shaft (22) rotates, the second bevel gear (27) drives the third rotating shaft (28) to rotate.

7. The bioengineering pharmaceutical raw material mixing device according to claim 6, characterized in that: The plurality of third stirring blades (19) are located in the partition tube (18), and the third rotating shaft (28) drives the third stirring blades (19) to rotate, thereby driving the liquid in the partition tube (18) to move upward.

8. The bioengineering pharmaceutical raw material mixing device according to claim 5, characterized in that: A plurality of the second rotating shafts (22) are symmetrically arranged, and a plurality of the first rotating shafts (16) are symmetrically arranged.

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