Traditional Chinese medicine formula for treating persistent fever of tumor patients

Abstract

The invention discloses a traditional Chinese medicine formula for treating persistent fever of tumor patients, and belongs to the technical field of traditional Chinese medicine formulas for treating high fever. Comprising the following components in parts by weight: 10-120 parts of folium isatidis or an extract thereof, 10-150 parts of radix ophiopogonis or an extract thereof, 10-120 parts of adenophora stricta or an extract thereof, 10-120 parts of Chinese yam or an extract thereof, 10-120 parts of radix scrophulariae or an extract thereof, 10-120 parts of wax gourd kernels or an extract thereof, 10-120 parts of gypsum or an extract thereof, 10-120 parts of radix trichosanthis or an extract thereof, and 10-120 parts of radix rehmanniae or an extract thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 120 parts of herba menthae or an extract thereof, 10 to 120 parts of herba eupatorii or an extract thereof, 1 to 10 parts of cornu bubali powder or an extract thereof and 1 to 10 parts of antelope horn powder or an extract thereof. The traditional Chinese medicine formula contains various herbal medicine components, each component has a unique pharmacological action, and the herbal medicine components can promote and complement each other and jointly act on the high fever symptom of a tumor patient, so that the purposes of rapidly abating fever, stabilizing the body temperature and relieving the symptom are achieved. The traditional Chinese medicine composition has lower toxic and side effects and is more suitable for long-term use of tumor patients.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine formulas for treating high fever, and in particular relates to a traditional Chinese medicine formula for treating tumor patients with persistent high fever. Background Art

[0002] In modern medicine, cancer patients often experience persistent high fever during treatment, especially after chemotherapy or radiotherapy. This persistent high fever not only increases the patient's discomfort, but may also cause further damage to the patient's immune system, affecting the treatment effect and quality of life. At present, the methods for treating high fever mainly include drug therapy and physical cooling, but these methods may have problems of dependence, side effects or limited effects. Especially in the special group of cancer patients, due to their physical constitution and the complexity of their condition, conventional antipyretic methods often fail to achieve the ideal therapeutic effect.

[0003] According to TCM theory, patients with persistent high fever need to restore their body balance through heat-clearing and detoxification, nourishing yin and reducing fire. However, existing TCM formulas for treating persistent high fever in patients with cancer may have problems such as inaccurate formulas, ineffective effects or limited scope of application. Summary of the invention

[0004] In view of the above situation, in order to overcome the defects of the prior art, the Chinese medicine formula of the present invention is specifically aimed at the symptoms of persistent high fever in tumor patients, combines traditional Chinese medicine theory and modern research results, and provides a more accurate and effective Chinese medicine formula.

[0005] In order to achieve the above-mentioned purpose, the following technical scheme is adopted: the present invention provides a traditional Chinese medicine formula for treating high fever in tumor patients, comprising the following components in parts by weight: 10-120 parts of isatis indigotica or its extract, 10-150 parts of ophiopogon or its extract, 10-120 parts of adenophora or its extract, 10-120 parts of yam or its extract, 10-120 parts of scrophularia or its extract, 10-120 parts of wax gourd seeds or its extract, 10-120 parts of gypsum or its extract, 10-120 parts of trichosanthes or its extract, 10-120 parts of rehmannia or its extract, 10-120 parts of mint or its extract, 10-120 parts of perilla or its extract, 1-10 parts of buffalo horn powder or its extract, and 1-10 parts of antelope horn powder or its extract.

[0006] Furthermore, the Chinese medicine formula includes the following components in parts by weight: 20-100 parts of isatis indigotica or its extract, 20-120 parts of ophiopogon or its extract, 20-100 parts of adenophora or its extract, 20-100 parts of yam or its extract, 20-100 parts of scrophularia or its extract, 20-100 parts of wax gourd seeds or its extract, 20-100 parts of gypsum or its extract, 20-100 parts of trichosanthes or its extract, 20-100 parts of rehmannia or its extract, 20-100 parts of mint or its extract, 20-100 parts of perilla or its extract, 2-8 parts of buffalo horn powder or its extract, and 2-8 parts of antelope horn powder or its extract.

[0007] Furthermore, the Chinese medicine formula includes the following components in parts by weight: 30-90 parts of isatis indigotica or its extract, 30-100 parts of ophiopogon or its extract, 30-90 parts of adenophora or its extract, 30-90 parts of yam or its extract, 30-90 parts of scrophularia or its extract, 30-90 parts of wax gourd seeds or its extract, 30-90 parts of gypsum or its extract, 30-90 parts of trichosanthes or its extract, 30-90 parts of rehmannia or its extract, 30-90 parts of mint or its extract, 30-90 parts of perilla or its extract, 2-7 parts of buffalo horn powder or its extract, and 2-7 parts of antelope horn powder or its extract.

[0008] Furthermore, the Chinese medicine formula includes the following components in parts by weight: 40-80 parts of isatis indigotica extract, 40-80 parts of ophiopogon extract, 40-80 parts of adenophora extract, 40-80 parts of yam extract, 40-80 parts of Scrophularia extract, 40-80 parts of wax gourd seed extract, 40-80 parts of gypsum extract, 40-80 parts of trichosanthes extract, 40-80 parts of rehmannia extract, 40-80 parts of peppermint extract, 40-80 parts of perilla extract, 3-7 parts of buffalo horn powder extract, and 3-7 parts of antelope horn powder extract.

[0009] Furthermore, the Chinese medicine formula includes the following components in parts by weight: 50-70 parts of isatis indigotica extract, 50-70 parts of ophiopogon extract, 50-70 parts of adenophora extract, 50-70 parts of yam extract, 50-70 parts of Scrophularia extract, 50-70 parts of wax gourd seed extract, 50-70 parts of gypsum extract, 50-70 parts of trichosanthes extract, 50-70 parts of rehmannia extract, 50-70 parts of peppermint extract, 50-70 parts of perilla extract, 3-6 parts of buffalo horn powder extract, and 3-6 parts of antelope horn powder extract.

[0010] Furthermore, the Chinese medicine formula can be made into granules, tablets, pills, capsules, powders, mixtures or oral liquids.

[0011] Furthermore, the Chinese medicine formula can be used to treat persistent high fever in tumor patients.

[0012] The beneficial effects of the present invention are: (1) The Chinese medicine formula of the present invention contains a variety of herbal ingredients, each of which has its own unique pharmacological effects. Folium Isatidis has the effects of clearing away heat and detoxifying, cooling blood and stopping bleeding; Radix Ophiopogonis can nourish yin and moisten the lungs, promote the production of body fluids and quench thirst. The synergistic effect of these ingredients in the formula, through reasonable proportions and scientific preparation, can promote and complement each other, and work together to treat the high fever symptoms of tumor patients, thereby achieving the purpose of rapidly reducing fever, stabilizing body temperature and alleviating symptoms. The synergistic effect of multiple ingredients not only improves the therapeutic effect, but also helps to reduce the side effects of a single drug, so that patients can receive treatment more safely and comfortably. Receive treatment.

[0013] (2) The herbal ingredients used in the Chinese medicine formula of the present invention are all natural plants. These plants have been used in traditional Chinese medicine for thousands of years, and their safety and effectiveness have been widely recognized. Compared with chemical synthetic drugs, natural herbal ingredients have lower toxic side effects and are more suitable for long-term use by cancer patients.

[0014] (3) This formula not only takes into account the immunosuppression and metabolic disorders caused by chemotherapy or radiotherapy in cancer patients, but also takes into account the patient's tolerance to drugs and individual differences, providing a more precise and effective treatment option. Through targeted treatment, it can significantly improve the antipyretic effect and reduce complications caused by high fever. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 The present invention provides an evaluation result of the efficacy of various embodiments of a traditional Chinese medicine formula for treating persistent high fever in tumor patients in treating persistent high fever in tumor patients.

[0016] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0018] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those familiar to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein may be applied to the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only and are not intended to limit the content of this application.

[0019] The experimental methods in the following examples are conventional methods unless otherwise specified, and the experimental materials used in the following examples are purchased from commercial channels unless otherwise specified. Example Example Example

[0020] Comparative Example 1 A Chinese medicine formula for treating persistent high fever in tumor patients The invention comprises the following components in parts by weight: 20 parts of isatis indigotica leaves, 20 parts of ophiopogon japonicus, 20 parts of adenophora radix, 20 parts of yam, 20 parts of scrophularia ningpoensis, 20 parts of wax gourd seeds, 20 parts of gypsum, 20 parts of radix trichosanthis, 20 parts of radix rehmanniae, 20 parts of mint, 20 parts of perilla frutescens, 2 parts of buffalo horn powder and 2 parts of antelope horn powder.

[0021] Comparative Example 2 A Chinese medicine formula for treating persistent high fever in tumor patients The invention comprises the following components in parts by weight: 80 parts of isatis indigotica leaves, 80 parts of ophiopogon japonicus, 80 parts of adenophora radix, 80 parts of yam, 80 parts of scrophularia ningpoensis, 80 parts of wax gourd seeds, 80 parts of gypsum, 80 parts of radix trichosanthis, 80 parts of radix rehmanniae, 80 parts of mint, 80 parts of perilla frutescens, 6 parts of buffalo horn powder and 6 parts of antelope horn powder.

[0022] Comparative Example 3 A Chinese medicine formula for treating persistent high fever in tumor patients The traditional Chinese medicine formula comprises the following components in parts by weight: 40 parts of isatis indigotica extract, 80 parts of ophiopogon extract, 40 parts of adenophora extract, 40 parts of yam extract, 80 parts of scrophularia extract, 80 parts of wax gourd seed extract, 80 parts of gypsum extract, 40 parts of trichosanthes extract, 40 parts of rehmannia extract, 40 parts of peppermint extract, 40 parts of perilla extract, 3 parts of buffalo horn powder extract, and 3 parts of antelope horn powder extract.

[0023] Comparative Example 4 A Chinese medicine formula for treating persistent high fever in tumor patients The traditional Chinese medicine formula includes the following components in parts by weight: 60 parts of isatis indigotica extract, 60 parts of ophiopogon extract, 60 parts of adenophora extract, 60 parts of yam extract, 60 parts of Scrophularia extract, 60 parts of wax gourd seed extract, 60 parts of gypsum extract, 60 parts of trichosanthes extract, 60 parts of rehmannia extract, 60 parts of peppermint extract, 60 parts of perilla extract, 5 parts of buffalo horn powder extract, and 5 parts of antelope horn powder extract.

[0024] Results Analysis The following experiments were conducted to evaluate the efficacy of each embodiment in treating persistent high fever in tumor patients: 1. Experimental group: The tumor patients with persistent high fever were given the Chinese medicine formula composition provided by Examples 1 to 4 of the present invention, 3 times a day, 9 g each time, 2 days as a course of treatment, and the body temperature was measured every 4 hours after the end of the course of treatment. No other drugs and methods for treating the disease were used during the course of treatment. Experimental groups 1-4 correspond to Examples 1-4 respectively; 2. Control group: patients with persistent high fever took western medicine to treat high fever. One course of treatment was 2 days. After one course of treatment, the body temperature was measured every 4 hours. No other drugs or methods were used to treat the disease during the treatment. 3. Measure the body temperature of patients in the experimental group and the control group before taking the medicine and after 4, 8, 12, 16, 20, and 24 hours of one course of treatment. The results are shown in the table. Figure 1 .

[0025] Depend on Figure 1 It can be seen that during the course of medical treatment with Western medicine, although the patient's body temperature quickly dropped to the normal body temperature of the human body, the subsequent measurement results showed that the patient recovered from the high fever symptoms. After taking the Chinese medicine formula composition provided by the present invention, the patient's high fever symptoms subsided after the end of one course of treatment, and maintained within the normal body temperature range in the subsequent period of time, indicating that the Chinese medicine formula of the present invention can relieve the symptoms of high fever in tumor patients, and there is no repeated fever.

[0026] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0027] The present invention and its implementation methods are described above, which is not restrictive. The drawings are only one of the implementation methods of the present invention, and the actual application is not limited thereto. In short, if ordinary technicians in the field are inspired by it and design methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention, they should all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine formula for treating persistent high fever in tumor patients, characterized in that: The invention comprises the following components in parts by weight: 10-120 parts of isatis indigotica or its extract, 10-150 parts of ophiopogon or its extract, 10-120 parts of adenophora or its extract, 10-120 parts of yam or its extract, 10-120 parts of scrophularia or its extract, 10-120 parts of wax gourd seeds or its extract, 10-120 parts of gypsum or its extract, 10-120 parts of trichosanthes or its extract, 10-120 parts of rehmannia or its extract, 10-120 parts of mint or its extract, 10-120 parts of perilla or its extract, 1-10 parts of buffalo horn powder or its extract, and 1-10 parts of antelope horn powder or its extract.

2. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 20-100 parts of isatis indigotica or its extract, 20-120 parts of ophiopogon or its extract, 20-100 parts of adenophora or its extract, 20-100 parts of yam or its extract, 20-100 parts of scrophularia or its extract, 20-100 parts of wax gourd seeds or its extract, 20-100 parts of gypsum or its extract, 20-100 parts of trichosanthes or its extract, 20-100 parts of rehmannia or its extract, 20-100 parts of mint or its extract, 20-100 parts of perilla or its extract, 2-8 parts of buffalo horn powder or its extract, and 2-8 parts of antelope horn powder or its extract.

3. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 2, characterized in that: The invention comprises the following components in parts by weight: 30-90 parts of isatis indigotica or its extract, 30-100 parts of ophiopogon or its extract, 30-90 parts of adenophora or its extract, 30-90 parts of yam or its extract, 30-90 parts of figwort or its extract, 30-90 parts of wax gourd seeds or its extract, 30-90 parts of gypsum or its extract, 30-90 parts of trichosanthes or its extract, 30-90 parts of rehmannia or its extract, 30-90 parts of mint or its extract, 30-90 parts of perilla or its extract, 2-7 parts of buffalo horn powder or its extract, and 2-7 parts of antelope horn powder or its extract.

4. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 3, characterized in that: The invention comprises the following components in parts by weight: 40-80 parts of isatis indigotica extract, 40-80 parts of ophiopogon extract, 40-80 parts of adenophora extract, 40-80 parts of yam extract, 40-80 parts of scrophularia extract, 40-80 parts of wax gourd seed extract, 40-80 parts of gypsum extract, 40-80 parts of trichosanthes extract, 40-80 parts of rehmannia extract, 40-80 parts of peppermint extract, 40-80 parts of perilla extract, 3-7 parts of buffalo horn powder extract and 3-7 parts of antelope horn powder extract.

5. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 4, characterized in that: The invention comprises the following components in parts by weight: 50-70 parts of isatis indigotica extract, 50-70 parts of ophiopogon extract, 50-70 parts of adenophora extract, 50-70 parts of yam extract, 50-70 parts of figwort extract, 50-70 parts of wax gourd seed extract, 50-70 parts of gypsum extract, 50-70 parts of trichosanthes extract, 50-70 parts of rehmannia extract, 50-70 parts of peppermint extract, 50-70 parts of perilla extract, 3-6 parts of buffalo horn powder extract and 3-6 parts of antelope horn powder extract.

6. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 5, characterized in that: The Chinese medicine formula can be made into granules, tablets, pills, capsules, powders, mixtures or oral liquids.

7. A Chinese medicine formula for treating persistent high fever in tumor patients according to claim 6, characterized in that: The traditional Chinese medicine formula can be used to treat persistent high fever in tumor patients.

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