Preparation method of performance optimization solution
By preparing a performance optimization solution with simple operation and low cost, the problem of complex and high cost of equipment parameter adjustment during the performance optimization process of inductively coupled plasma mass spectrometer is solved, and the optimal state of the instrument and analysis accuracy are improved.
Patent Information
- Application Number
- CN202411252625.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-09
- Publication Date
- 2024-12-13
AI Technical Summary
The existing inductively coupled plasma mass spectrometers have problems with complex and high cost in terms of performance optimization, which affects the stability and analysis accuracy of the instrument.
By preparing a performance optimization solution that is simple to operate, low cost, safe and environmentally friendly, the specific steps include purifying concentrated nitric acid and concentrated hydrochloric acid, adding ultrapure water, preparing a standard solution of elemental metals, and obtaining a performance optimization solution through dilution, which is used to optimize the inductance Double charge yield and oxide yield of coupled plasma mass spectrometer.
The optimal state of inductively coupled plasma mass spectrometer is achieved, reducing the complexity and cost of equipment parameter adjustment, and improving the signal strength and analysis accuracy of the instrument.
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Figure CN119124779A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of preparation of an inductively coupled plasma mass spectrometer performance optimization solution, and in particular to a preparation method of the performance optimization solution. Background Art
[0002] Inductively coupled plasma mass spectrometer (ICP-MS) is an instrument used for elemental analysis in the fields of environmental protection, food, geology, metals, biological samples, chemical materials analysis, etc. Instrument performance parameters play a vital role in the analysis of target elements. Therefore, the equipment parameters need to be optimized each time the equipment is used, such as: nebulizer flow, emission power of the inductively coupled coil, voltage of the ion lens, double charge yield, oxide yield, detector voltage, quadrupole voltage, torch position, etc. Through parameter optimization and adjustment, the plasma is continuously and stably ionized, and the ions of the target element reach the detector through the quadrupole, while the interference of the generated oxides and double charges is reduced, and the equipment is in the best state.
[0003] The performance optimization solution is a solution used to optimize the performance of the inductively coupled plasma mass spectrometer, such as the double charge yield and oxide yield. Only when the instrument reaches the best measurement state can elemental analysis be performed.
[0004] In view of this, the present invention is proposed. Summary of the invention
[0005] Based on the above background technology content, the technical problem to be solved by the present invention is to provide a method for preparing a performance-optimized solution. The preparation method of the present invention is simple to operate, low in cost, safe and environmentally friendly, and is suitable for industrial production.
[0006] Specifically, the method for preparing the performance optimized solution comprises the following steps:
[0007] 1) purifying concentrated nitric acid and concentrated hydrochloric acid respectively;
[0008] 2) adding the concentrated nitric acid and concentrated hydrochloric acid in step 1) into ultrapure water;
[0009] 3) using the solution of step 2) to prepare a stock solution of standard solutions of elemental barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb);
[0010] 4) Diluting the stock solution in step 3) with step 2) to obtain a performance optimized solution.
[0011] Furthermore, in the step 1), the concentrations of Sc, Ni, Ti, Ca, Na, Fe, Sn, As, Rh, Cd, Mo, Ru, Hg, Hg, Pt, Li, Co, In and U in the purified concentrated hydrochloric acid and concentrated nitric acid are less than 0.05 μg / L.
[0012] Furthermore, in the step 2), the volume fraction of concentrated nitric acid is 1 to 10%.
[0013] Furthermore, in the step 2), the volume fraction of concentrated hydrochloric acid is 0-2%.
[0014] Furthermore, in the step 3), the standard solutions of elemental barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb) are certified standard substances, and the concentration is 1000 μg / mL.
[0015] Furthermore, in step 3), the concentration of the stock solution is 10 μg / mL.
[0016] Furthermore, in step 4), the concentration of the performance optimization solution is 1.0 μg / L.
[0017] On the other hand, the present invention provides a performance optimized solution prepared by the above preparation method and its application in an inductively coupled plasma mass spectrometer (ICP-MS).
[0018] The present invention has the following technical effects:
[0019] The preparation method provided by the invention is simple to operate, low in cost, safe and environmentally friendly, and increases the feasibility of industrial production. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.
[0021] Figure 1 : Flow chart for the preparation of performance tuning solutions. DETAILED DESCRIPTION
[0022] In order to explain the present invention more clearly, the present invention is further described below in conjunction with preferred embodiments. It should be understood by those skilled in the art that the following specific description is illustrative rather than restrictive, and should not be used to limit the scope of protection of the present invention.
[0023] Embodiment 1:
[0024] Concentrated nitric acid and concentrated hydrochloric acid are purified respectively, and the concentrations of Sc, Ni, Ti, Ca, Na, Fe, Sn, As, Rh, Cd, Mo, Ru, Hg, Hg, Pt, Li, Co, In and U in the purified concentrated nitric acid and concentrated hydrochloric acid are required to be less than 0.05 μg / L; 25 mL of concentrated nitric acid, 5 mL of concentrated hydrochloric acid and 470 mL of primary deionized water (the volume fractions of concentrated nitric acid and concentrated hydrochloric acid are 5% and 1% respectively) are added to a 500 mL beaker. %), shake well; respectively transfer 0.5mL of barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb) standard solutions into 50mL volumetric flasks, and dilute to scale with the above solutions, shake well, and obtain stock solutions; then dilute the stock solutions to 1.0μg / L with the above solutions to obtain performance optimization solutions.
[0025] The obtained performance optimized solution product is used to optimize the performance parameters of inductively coupled plasma mass spectrometer (ICP-MS). The signal strength of the optimized instrument is Be≥2000, In≥40000, U≥30000, Ce++ / Ce≤0.03, CeO / Ce≤0.03, and the instrument reaches the best state.
[0026] Embodiment 2:
[0027] Concentrated nitric acid and concentrated hydrochloric acid are purified respectively, and the concentrations of Sc, Ni, Ti, Ca, Na, Fe, Sn, As, Rh, Cd, Mo, Ru, Hg, Hg, Pt, Li, Co, In and U in the purified concentrated nitric acid and concentrated hydrochloric acid are required to be lower than 0.05 μg / L; 10 mL of concentrated nitric acid and 490 mL of first-grade deionized water (the volume fraction of the concentrated nitric acid is 2%) are added to a 500 mL beaker respectively, and shaken well; 1.0 mL of barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb) standard solutions are respectively transferred to a 100 mL volumetric flask, and the above solutions are used to make up to the scale, and shaken well to obtain a stock solution; and the stock solution is diluted to 1.0 μg / L with the above solution to obtain a performance optimization solution.
[0028] The obtained performance optimized solution product is used to optimize the performance parameters of inductively coupled plasma mass spectrometer (ICP-MS). The signal strength of the optimized instrument and equipment is Li≥50000, Co≥100000, In≥200000, U≥300000, Ba++ / Ba≤0.03, CeO / Ce≤0.03, and the instrument and equipment reaches the best state.
[0029] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be covered by the scope of the claims of the present invention.
Claims
1. A method for preparing a performance optimized solution, characterized in that: The preparation method comprises the following steps: 1) purifying concentrated nitric acid and concentrated hydrochloric acid respectively; 2) adding the concentrated nitric acid and concentrated hydrochloric acid in step 1) into primary deionized water; 3) using the solution of step 2) to prepare a stock solution of standard solutions of elemental barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb); 4) Diluting the stock solution in step 3) with step 2) to obtain a performance optimized solution.
2. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 1), the concentrations of Sc, Ni, Ti, Ca, Na, Fe, Sn, As, Rh, Cd, Mo, Ru, Hg, Hg, Pt, Li, Co, In and U in the purified concentrated hydrochloric acid and concentrated nitric acid are less than 0.05 μg / L.
3. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 2), the volume fraction of concentrated nitric acid is 1 to 10%.
4. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 2), the volume fraction of concentrated hydrochloric acid is 0-2%.
5. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 3), the standard solutions of elemental barium (Ba), bismuth (Bi), beryllium (Be), cerium (Ce), cobalt (Co), indium (In), lithium (Li), uranium (U), magnesium (Mg), yttrium (Y), thallium (Tl), iron (Fe), and lead (Pb) are certified standard substances, and the concentration is 1000 μg / mL.
6. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 3), the concentration of the stock solution is 10 μg / mL.
7. The method for preparing a performance optimized solution according to claim 1, characterized in that: In the step 4), the concentration of the performance optimization solution is 1.0 μg / L.
8. The performance optimized solution prepared according to the method for preparing a performance optimized solution according to any one of claims 1 to 7.
9. Use of a performance optimized solution according to claim 8 in an inductively coupled plasma mass spectrometer (ICP-MS).