Sustained-release medicine compression molding device

By adopting a combination design of a hoisting device and a knocking device in the sustained-release drug compression molding device, the drug accumulation problem is solved, the uniformity and flexibility of drug distribution are achieved, and the maintenance cost is reduced. It is suitable for the slow-down of multi-layer structures Release drug preparation.

CN119141941AInactive Publication Date: 2024-12-17赵桂鹏
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Patent Information

Application Number
CN202411567893.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-05
Publication Date
2024-12-17
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing sustained-release drug compression molding devices are prone to drug accumulation during drug filling, resulting in uneven drug distribution, affecting the quality and performance of the final product, and have complex structure and high maintenance costs and poor flexibility.

Method used

A sustained release drug pressing molding device including an operating table, a hoisting device, a knocking device and a push rack is designed. Through the multi-stage lifting design of the hoisting device and the periodic knocking of the tapping device, the drug accumulation is avoided, and Multi-layer pressing is achieved through multiple pushing materials on the push rack to ensure uniform distribution of drugs, clever structure and low cost.

Benefits of technology

The uniformity of drug distribution is achieved, the maintenance cost of the device is reduced, and the flexibility is improved. The ratio can be adjusted according to different drug layers, and it is suitable for the preparation of sustained-release drugs with multi-layer structures.

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Abstract

The invention discloses a sustained-release medicine compression molding device which comprises an operation table, a jacking device, a lifting plate, a knocking device, a pushing frame and a stamping device, and a plurality of die holes are formed in the operation table; the lifting plate is arranged below the operation table in a manner of moving up and down, a plurality of plugs are arranged on the lifting plate, the plugs correspond to the die holes in a one-to-one manner, and an avoiding groove is formed in the lifting plate; the jacking device is arranged at the bottom of the operation table; a knocking device is arranged at the bottom of the operation table. The driving end of the knocking device is connected with the rotating end of the jacking device. The material pushing frame is rotatably arranged on the operation table, a plurality of material frames are arranged in the material pushing frame, and various kinds of medicine are placed in the material frames respectively; and the stamping device is erected above the operation table. Multi-layer pressing of different medicine layers can be achieved, medicine entering the mold holes can be effectively prevented from being stacked through knocking of the knocking device, and it is guaranteed that the medicine is evenly distributed.
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Description

Technical Field

[0001] The invention relates to the technical field of medicine compression, in particular to a sustained-release medicine compression molding device. Background Art

[0002] With the development of medical technology, sustained-release drugs have attracted widespread attention because of their ability to prolong drug release time, reduce the number of dosing times, and improve patient compliance and therapeutic effects.

[0003] In the preparation process of sustained-release drugs, the physical form of the drug has an important influence on its release behavior. For example, metoprolol sustained-release tablets usually contain a fast-release layer and a slow-release layer. The fast-release layer releases the drug quickly after taking it and quickly reaches the therapeutic concentration, while the slow-release layer continuously releases the drug to maintain a long-term therapeutic effect. Another example is aspirin targeted-release tablet. The targeted-release sustained-release tablet is designed with a specific drug layer to release the drug in a specific part of the intestine, reducing irritation to the gastric mucosa. Therefore, how to efficiently and accurately prepare a multi-layered sustained-release drug has become a research focus.

[0004] At present, common sustained-release drug compression molding devices mainly adopt a single-press wheel or multi-press wheel design, which is suitable for conventional two-layer or three-layer compression. Although the single-press wheel design has a simple structure and low cost, it has poor flexibility. Although the multi-press wheel design can achieve compression of more layers, it has a complex structure and high maintenance cost. In addition, existing compression molding devices are prone to drug accumulation during the drug filling process, resulting in uneven drug distribution, affecting the quality and performance of the final product. Summary of the invention

[0005] The present invention aims to solve one of the technical problems in the above-mentioned technology at least to some extent.

[0006] To achieve the above-mentioned purpose, the first aspect of the present invention proposes a sustained-release drug compression molding device, comprising: an operating table, a lifting device, a lifting plate, a knocking device, a pushing rack and a punching device, wherein a plurality of die holes are provided in a fan-shaped area on the operating table; the lifting plate can be moved up and down and is arranged below the operating table, a plurality of plugs are provided on the lifting plate, and the plurality of plugs correspond to the plurality of die holes one by one, and an avoidance groove is provided on the lifting plate; the lifting device is arranged at the bottom of the operating table to lift the lifting plate so that the plugs can be lifted and lowered in multiple stages in the die holes; A knocking device is arranged at the bottom of the operating table above the avoidance groove, and the driving end of the knocking device is connected to the rotating end of the lifting device through a meshing bevel gear set, and the knocking end of the knocking device periodically knocks the operating table; the pushing rack is arranged on the operating table and is connected to the driving end of the knocking device, and a plurality of material frames are arranged in the pushing rack, and a plurality of medicines are respectively placed in the plurality of material frames, and a notch matching a plurality of mold holes in a fan-shaped area is arranged outside the pushing rack; the stamping device is arranged above the operating table to press the various medicines in the mold holes.

[0007] In addition, the sustained-release drug compression molding device proposed in the present invention may also have the following additional technical features:

[0008] As a further description of the above technical solution: a vertically downward connecting rod is provided at the bottom of the operating table, a limiting sleeve is provided at the bottom of the lifting plate, and the limiting sleeve is provided on the connecting rod, an extrusion spring is provided outside the limiting sleeve, and the two ends of the extrusion spring are respectively connected to the lifting plate and the bottom of the connecting rod; a rotatable rotating roller is provided on the lifting plate, and the rotating roller is in contact with the lifting end of the lifting device.

[0009] As a further description of the above technical solution: the lifting device includes a first rotating shaft, a driving motor and a lifting cam, wherein the first rotating shaft is arranged at the bottom of the operating table through a mounting frame and is located below the lifting plate; the driving motor is arranged on the mounting frame and is connected to the first rotating shaft through a transmission structure; the lifting cam is arranged on the first rotating shaft, and the outer ring of the lifting cam is a plurality of arc surfaces with a radius increasing in steps along the axial direction; wherein the rotating roller is in contact and connected with the outer ring of the lifting cam.

[0010] As a further description of the above technical solution: the transmission structure includes a driving wheel, a driven wheel and a transmission chain, wherein the driving wheel is connected to the output end of the driving motor; the driven wheel is arranged on the first rotating shaft; and the transmission chain connects the driving wheel and the driven wheel.

[0011] As a further description of the above technical solution: the knocking device includes a second rotating shaft, a lever, a knocking rod and a tension spring, wherein one end of the second rotating shaft is connected to the rotating end of the jacking device through the meshing bevel gear set, and the other end is rotatably connected to the bottom of the operating table through a bearing sleeve; multiple levers are respectively arranged on the second rotating shaft; the knocking rod is rotatably arranged at the bottom of the operating table through a pivot frame, and is connected to the bottom of the operating table through the tension spring; when the lever rotates with the second rotating shaft, one end of the knocking rod is pushed up to make the tension spring in a stretched state, and after the lever passes the knocking rod, the knocking end of the knocking rod rebounds and knocks on the bottom of the operating table.

[0012] As a further description of the above technical solution: a plurality of stamping dies are arranged on the stamping end of the stamping device, and the plurality of stamping dies correspond one-to-one to the plurality of die holes, and a hydraulic cylinder is connected to the top of the stamping device.

[0013] As a further description of the above technical solution: a material guiding device is arranged on the side wall of the operating table outside the plurality of mold holes, and the material guiding device comprises an arc-shaped baffle plate, an arc-shaped rotating plate and a torsion spring, wherein the arc-shaped baffle plate is arranged on the side wall of the operating table; the arc-shaped rotating plate can be rotatably arranged on the extension portion outside the arc-shaped baffle plate, and the torsion spring is sleeved on the rotating shaft of the arc-shaped rotating plate, and the two ends of the torsion spring are respectively connected to the bottom of the rotating shaft and the extension portion of the arc-shaped rotating plate.

[0014] As a further description of the above technical solution: a rolling wheel is arranged at one end of the arc-shaped rotating plate away from the rotating shaft.

[0015] As a further description of the above technical solution: a receiving bucket is arranged at the bottom of the material guiding device.

[0016] According to the sustained-release drug compression molding device of the present invention, through the multi-stage lifting design of the lifting device, the plug can be lifted and lowered in multiple stages in the mold hole, and in conjunction with the multiple pushing of the pushing rack, multi-layer compression of different drug layers can be achieved, and while pushing the material, the knocking device can knock on the operating table to effectively avoid the accumulation of drugs entering the mold hole, ensuring uniform distribution of the drugs. The entire device has an ingenious structure and low cost, and the proportion of different drug layers can be adjusted by replacing the lifting end of the lifting device, which has higher flexibility.

[0017] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The above and / or additional aspects and advantages of the present invention will become apparent and easily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which:

[0019] Figure 1 is a schematic structural diagram of a sustained-release drug compression molding device according to an embodiment of the present invention;

[0020] Figure 2 is a schematic structural diagram of a sustained-release drug compression molding device according to another embodiment of the present invention;

[0021] Figure 3 is a schematic diagram of a local A enlarged structure according to an embodiment of the present invention;

[0022] Figure 4 is a schematic structural diagram of a jacking device according to an embodiment of the present invention;

[0023] Figure 5 is a schematic structural diagram of a lifting plate according to an embodiment of the present invention;

[0024] Figure 6 is a schematic structural diagram of a material pusher according to an embodiment of the present invention;

[0025] Figure 7 is a schematic structural diagram of a material guiding device according to an embodiment of the present invention;

[0026] Figure 8 is a schematic diagram of the working state of a jacking device according to an embodiment of the present invention;

[0027] Fig. 9 is a schematic diagram of the working state of a jacking device according to another embodiment of the present invention;

[0028] Fig.10 is a schematic structural diagram of a lifting cam according to an embodiment of the present invention;

[0029] As shown in the figure:

[0030] 100, operating table; 101, die hole; 102, connecting rod; 103, extrusion spring; 200, lifting device; 210, first rotating shaft; 220, first driving motor; 230, lifting cam; 401, meshing bevel gear set; 300, lifting plate; 301, plug; 302, avoidance groove; 303, rotating roller; 304, limiting sleeve; 400, knocking device; 410, second rotating shaft; 420, shifting rod; 430, knocking rod; 440, stretching spring; 500, pushing rack; 501, material frame; 502, notch; 600, stamping device; 601, stamping die; 602, hydraulic cylinder; 700, material guiding device; 710, arc baffle; 720, arc rotating plate; 721, rolling wheel; 730, torsion spring. DETAILED DESCRIPTION

[0031] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0032] The sustained-release drug compression molding device according to an embodiment of the present invention will be described below with reference to the accompanying drawings.

[0033] like Figure 1 and Figure 2 As shown, the sustained-release drug compression molding device according to the embodiment of the present invention may include an operating table 100 , a lifting device 200 , a lifting plate 300 , a knocking device 400 , a pushing rack 500 and a punching device 600 .

[0034] A plurality of die holes 101 are provided in a fan-shaped area on the operating table 100 . The die holes 101 can be set according to the shape of the tablets to be pressed, such as a cylindrical or elliptical cylindrical shape.

[0035] like Figure 5 As shown, the lifting plate 300 can be moved up and down and is arranged below the operating table 100. A plurality of plugs 301 are arranged on the lifting plate 300, and the plurality of plugs 301 correspond one by one to the plurality of mold holes 101. An avoidance groove 302 is opened on the lifting plate 300.

[0036] In one embodiment of the present invention, Figure 4 As shown, a vertical downward connecting rod 102 is provided at the bottom of the operating platform 100, a limiting sleeve 304 is provided at the bottom of the lifting plate 300, and the limiting sleeve 304 is sleeved on the connecting rod 102. An extrusion spring 103 is provided outside the limiting sleeve 304, and the two ends of the extrusion spring 103 are respectively connected to the lifting plate 300 and the bottom of the connecting rod 102.

[0037] It should be noted that when the lifting plate 300 moves up and down, it can drive the plug 301 to move in the mold hole 101, and the reserved space in the mold hole 101 is used to fill the medicine. Through the multi-stage descent of the lifting plate 300, the reserved space in the mold hole 101 gradually increases to fill different medicines in layers, which is convenient for subsequent pressing. After the pressing is completed, the rise of the lifting plate 300 can drive the plug 301 to push the pressed medicine in the mold hole 101 out.

[0038] The lifting device 200 is arranged at the bottom of the operating table 100 to lift the lifting plate 300 so that the plug 301 can be lifted and lowered in multiple stages in the mold hole 101. A rotatable rotating roller 303 is arranged on the lifting plate 300, and the rotating roller 303 is in contact with the lifting end of the lifting device 200. The lifting of the lifting device 200 can push up the rotating roller 303, thereby enabling the lifting plate 300 to be lifted and lowered.

[0039] In one embodiment of the present invention, Figure 4 As shown, the lifting device 200 includes a first rotating shaft 210 , a first driving motor 220 and a lifting cam 230 .

[0040] The first rotating shaft 210 is arranged at the bottom of the operating platform 100 through a mounting frame and is located below the lifting plate 300. The first driving motor 220 is arranged on the mounting frame and is connected to the first rotating shaft 210 through a transmission structure. The lifting cam 230 is arranged on the first rotating shaft 210. Fig.10 As shown, the outer ring of the lifting cam 230 is a plurality of arc surfaces with a radius increasing in a step-like manner in the axial direction, wherein the rotating roller 303 is in contact and connected with the outer ring of the lifting cam 230 .

[0041] It should be noted that when the lifting cam 230 rotates, due to the difference between the multiple arc surfaces, when the lifting cam 230 follows the first rotating shaft 210 to rotate, the lifting cam 230 can lift the active roller to different heights to drive the displacement of the lifting plate 300, thereby realizing the position change of the plug 301 in the mold hole 101.

[0042] A knocking device 400 is provided at the bottom of the operating platform 100 above the avoidance groove 302 . The driving end of the knocking device 400 is connected to the rotating end of the jacking device 200 through a meshing bevel gear set 401 . The knocking end of the knocking device 400 knocks the operating platform 100 periodically.

[0043] To clearly explain the above embodiment, in one embodiment of the present invention, Figure 3 As shown, the knocking device 400 includes a second rotating shaft 410 , a lever 420 , a knocking rod 430 and a tension spring 440 .

[0044] One end of the second rotating shaft 410 is connected to the rotating end of the jacking device 200 through the meshing bevel gear set 401, and the other end is rotatably connected to the bottom of the operating platform 100 through a bearing sleeve.

[0045] A plurality of levers 420 are respectively disposed on the second rotating shaft 410 . The knocking lever 430 is rotatably disposed at the bottom of the operating platform 100 via a pivot frame and is connected to the bottom of the operating platform 100 via a tension spring 440 .

[0046] When the lever 420 rotates following the second rotating shaft 410 , one end of the knocking rod 430 is pushed upward to put the tension spring 440 in a tensioned state. After the lever 420 passes the knocking rod 430 , the knocking end of the knocking rod 430 rebounds and knocks on the bottom of the operating table 100 .

[0047] It should be noted that when the first rotating shaft 210 of the lifting device 200 rotates, the second rotating shaft 410 can be driven to rotate by the meshing bevel gear set 401, so that the knocking device 400 can periodically knock on the bottom of the operating platform 100.

[0048] The pusher frame 500 can be rotatably arranged on the operating table 100. Figure 6 As shown, a plurality of material frames 501 are arranged inside the pusher rack 500 , and a plurality of medicines are placed in the plurality of material frames 501 , respectively. A notch 502 matching the fan-shaped areas of the plurality of die holes 101 is arranged outside the pusher rack 500 .

[0049] As a possible scenario, the pusher rack 500 is connected via a second drive motor (not shown) disposed in the avoidance groove 302, and the second drive motor is electrically connected to the lifting device 200 via a controller. It should be noted that when planning the position of the second drive motor, it is necessary to consider the avoidance knocking device 400 to avoid interference.

[0050] As another possible situation, the pusher frame 500 is connected via a second drive motor (not shown) mounted on the top, and the second drive motor is electrically connected to the lifting device 200 via a controller.

[0051] The punching device 600 is mounted above the operating table 100 to press the various drugs in the die hole 101, wherein a plurality of punching dies 601 are arranged on the punching end of the punching device 600, and the plurality of punching dies 601 correspond one-to-one to the plurality of die holes 101, and a hydraulic cylinder 602 is connected to the top of the punching device 600.

[0052] Specifically, if Figures 1 to 10 As shown, when the relevant staff is performing tabletting operation on the sustained-release drug, the relevant staff rotates the notch 502 of the pushing rack 500 to the die hole 101, and puts the drugs to be layered into different material frames 501 in sequence.

[0053] In the initial state, the maximum arc surface of the outer ring of the lifting cam 230 pushes the rotating roller 303 so that the plug 301 on the lifting plate 300 completely blocks the mold hole 101. At this time, the controller controls the rotation of the pushing rack 500, so that the medicine in the first material frame 501 is pushed to the mold hole 101.

[0054] As the driving motor starts, the driving motor drives the first rotating shaft 210 to rotate through the transmission structure, and the lifting cam 230 follows the rotation. After the maximum arc surface of the outer ring of the lifting cam 230 rotates, the second largest arc surface of the outer ring of the lifting cam 230 rotates to the rotating roller 303. At this time, since the outer ring at the top of the lifting cam 230 becomes smaller, the rotating roller 303 drops together due to the gravity of the lifting plate 300 and the reset effect of the extrusion spring 103 until the rotating roller 303 contacts the bottom of the lifting cam 230. At this time, since the plug 301 follows the descent of the lifting plate 300, a reserved position appears in the mold hole 101.

[0055] Since the first material frame 501 is located at the die hole 101 , when a reserved position appears in the die hole 101 , the medicine in the first material frame 501 falls into the reserved position in the die hole 101 .

[0056] The controller monitors the rotation angle of the first rotating shaft 210, and controls the pushing rack 500 to continue rotating. As a result, the medicine in the subsequent material frame 501 is pushed to the mold hole 101. Since the reserved position has been filled with the medicine in the first material frame 501, it is necessary to wait for the plug 301 to descend before continuing to fill.

[0057] As the first rotating shaft 210 continues to rotate, the outer circle at the top of the lifting cam 230 becomes smaller in steps, and the lifting plate 300 continues to descend following the position of the top of the lifting cam 230, and a new reserved position appears. Other subsequent drugs are refilled at the new reserved position, and this cycle repeats.

[0058] When the lifting device 200 is driven, the second rotating shaft 410 follows the rotation through the meshing bevel gear set 401 to drive the lever 420 to rotate, and the lever 420 pushes one end of the knocking rod 430 to put the tension spring 440 in a tensioned state. After the lever 420 passes the knocking rod 430, the knocking end of the knocking rod 430 rebounds and knocks on the bottom of the operating table 100, generating vibration, thereby preventing the drug from accumulating in the mold hole 101 and promoting the drug to follow the plug 301 to descend.

[0059] When the lifting cam 230 drives the lifting plate 300 to descend to the lowest position, the limiting sleeve 304 abuts against the limiting block at the bottom of the connecting rod 102, and all the drugs are arranged in layers in order in the die hole 101. The pushing rack 500 rotates the notch 502 to the die hole 101, and the punching device 600 presses down to punch the drugs in the die hole 101 into sheets and then resets them.

[0060] After the lifting cam 230 continues to rotate, the top of the lifting cam 230 changes from the lowest position to the highest position, and the lifting cam 230 pushes up the rotating roller 303, so that the plug 301 on the lifting plate 300 pushes up the punched medicine, and after the pushing rack 500 continues to rotate, the pushed up punched medicine is pushed out, and so on.

[0061] It should be noted that when the relevant staff needs to adjust the ratio between each layer of the sustained-release drug, it can be done by replacing the matching lifting cam 230 .

[0062] In one embodiment of the present invention, the transmission structure includes a driving wheel, a driven wheel and a transmission chain.

[0063] The driving wheel is connected to the output end of the first driving motor 220 , the driven wheel is arranged on the first rotating shaft 210 , and the transmission chain connects the driving wheel and the driven wheel.

[0064] It should be noted that when the first driving motor 220 is started, the output end of the first driving motor 220 drives the driving wheel to rotate, so that the transmission chain drives the driven wheel to rotate, and further the first rotating shaft 210 rotates.

[0065] In one embodiment of the present invention, Figure 1 and Figure 7 As shown, a material guiding device 700 is arranged on the side wall of the operating table 100 outside the plurality of die holes 101 , and the material guiding device 700 includes an arc-shaped baffle plate 710 , an arc-shaped rotating plate 720 and a torsion spring 730 .

[0066] Among them, the arc-shaped baffle 710 is arranged on the side wall of the operating table 100, the arc-shaped rotating plate 720 can be rotatably arranged on the extension part outside the arc-shaped baffle 710, and a torsion spring 730 is sleeved on the rotating shaft of the arc-shaped rotating plate 720, and the two ends of the torsion spring 730 are respectively connected to the bottom of the rotating shaft and the extension part of the arc-shaped rotating plate 720.

[0067] It should be noted that when the sustained-release drug is tableted, as the pusher rack 500 rotates, the end of the arc-shaped rotating plate 720 away from the rotating axis is always in contact with the outer wall of the pusher rack 500. When the punched tablet drug is pushed out, as the notch 502 of the pusher rack 500 rotates, the punched tablet drug is pushed by the notch 502. At this time, the arc-shaped rotating rack is reset by the torsion spring 730, so that the end of the arc-shaped rotating rack away from the rotating axis is in contact with the notch 502, and as the notch 502 rotates, the arc-shaped rotating rack scrapes the punched tablet drug out of the notch 502, and as the pusher rack 500 continues to rotate, the arc-shaped rotating rack is blocked by the material frame 501 and in contact with the outer wall of the material frame 501, thereby not affecting the rotation of the pusher rack 500.

[0068] In order to further improve the contact smoothness between the arc-shaped rotating plate 720 and the material pushing frame 500 , a rolling wheel 721 is provided at one end of the arc-shaped rotating plate 720 away from the rotating shaft.

[0069] In addition, a receiving bucket is provided at the bottom of the material guiding device 700 to receive the medicines that are scraped off from the arc-shaped rotating frame and punched into tablets.

[0070] In summary, according to the sustained-release drug compression molding device of the embodiment of the present invention, through the multi-stage lifting design of the lifting device 200, the plug 301 can be lifted and lowered in multiple stages in the die hole 101, and cooperate with the multiple pushing of the pushing frame 500, so as to realize multi-layer pressing of different drug layers, and at the same time of pushing the material, through the knocking device 400 knocking on the operating table 100, it can effectively avoid the accumulation of drugs entering the die hole 101, and ensure the uniform distribution of drugs, the whole device structure is ingenious and the cost is low, and the proportion of different drug layers can be adjusted by replacing the lifting end of the lifting device 200, which has higher flexibility.

[0071] In the description of this specification, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0072] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0073] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations of the present invention. A person skilled in the art may change, modify, replace and vary the above embodiments within the scope of the present invention.

Claims

1. A sustained-release drug compression molding device, characterized in that: include: An operating table (100), a lifting device (200), a lifting plate (300), a knocking device (400), a material pushing rack (500) and a punching device (600), wherein: The operating table (100) is provided with a plurality of die holes (101) in a fan-shaped area; The lifting plate (300) is movable up and down and is arranged below the operating table (100); a plurality of plugs (301) are arranged on the lifting plate (300); and the plurality of plugs (301) correspond to the plurality of die holes (101) one by one; and an avoidance groove (302) is opened on the lifting plate (300); The lifting device (200) is arranged at the bottom of the operating platform (100) to lift the lifting plate (300) so that the plug (301) can be lifted and lowered in multiple stages in the die hole (101); A knocking device (400) is provided at the bottom of the operating table (100) above the avoidance groove (302), the driving end of the knocking device (400) is connected to the rotating end of the jacking device (200) via a meshing bevel gear set (401), and the knocking end of the knocking device (400) periodically knocks the operating table (100); The pusher rack (500) is rotatably arranged on the operating table (100), a plurality of material frames (501) are arranged inside the pusher rack (500), a plurality of medicines are respectively placed inside the plurality of material frames (501), and a notch (502) matching the fan-shaped areas of the plurality of die holes (101) is arranged outside the pusher rack (500); The punching device (600) is mounted above the operating table (100) to press the various medicines in the die hole (101).

2. The sustained-release drug compression molding device according to claim 1, characterized in that: A connecting rod (102) pointing vertically downward is provided at the bottom of the operating platform (100); a limiting sleeve (304) is provided at the bottom of the lifting plate (300), and the limiting sleeve (304) is sleeved on the connecting rod (102); an extrusion spring (103) is provided on the outer sleeve of the limiting sleeve (304), and two ends of the extrusion spring (103) are respectively connected to the lifting plate (300) and the bottom of the connecting rod (102); a rotatable rotating roller (303) is provided on the lifting plate (300), and the rotating roller (303) is in contact with the lifting end of the lifting device (200).

3. The sustained-release drug compression molding device according to claim 2, characterized in that: The lifting device (200) comprises a first rotating shaft (210), a first driving motor (220) and a lifting cam (230), wherein: The first rotating shaft (210) is arranged at the bottom of the operating platform (100) through a mounting frame and is located below the lifting plate (300); The driving motor (220) is arranged on a mounting frame and is connected to the first rotating shaft (210) via a transmission structure; The lifting cam (230) is arranged on the first rotating shaft (210), and the outer ring of the lifting cam (230) is a plurality of arc surfaces whose radii increase in a step-like manner in the axial direction; Wherein, the rotating roller (302) is in contact and connected with the outer ring of the lifting cam (230).

4. The sustained-release drug compression molding device according to claim 3, characterized in that: The transmission structure includes a driving wheel, a driven wheel and a transmission chain, wherein: The driving wheel is connected to the output end of the first driving motor (220); The driven wheel is arranged on the first rotating shaft (210); The transmission chain connects the driving wheel and the driven wheel.

5. The sustained-release drug compression molding device according to claim 1, characterized in that: The knocking device (400) comprises a second rotating shaft (410), a lever (420), a knocking rod (430) and a tension spring (440), wherein: One end of the second rotating shaft (410) is connected to the rotating end of the jacking device (200) through the meshing bevel gear set (401), and the other end is rotatably connected to the bottom of the operating platform (100) through a bearing sleeve; The plurality of shifting rods (420) are respectively arranged on the second rotating shaft (410); The knocking rod (430) is rotatably arranged at the bottom of the operating table (100) via a pivot frame, and is connected to the bottom of the operating table (100) via the tension spring (440); When the shifting rod (420) rotates following the second rotating shaft (410), one end of the knocking rod (430) is pushed upward to put the tension spring (440) in a tensioned state, and after the shifting rod (420) passes the knocking rod (430), the knocking end of the knocking rod (430) rebounds and knocks on the bottom of the operating table (100).

6. The sustained-release drug compression molding device according to claim 1, characterized in that: A plurality of stamping dies (601) are arranged on the stamping end of the stamping device (600), and the plurality of stamping dies (601) correspond one-to-one to the plurality of die holes (101), and a hydraulic cylinder (602) is connected to the top of the stamping device (600).

7. The sustained-release drug compression molding device according to claim 1, characterized in that: A material guiding device (700) is arranged on the side wall of the operating table (100) outside the plurality of die holes (101), and the material guiding device (700) comprises an arc-shaped baffle plate (710), an arc-shaped rotating plate (720) and a torsion spring (730), wherein: The arc-shaped baffle (710) is arranged on the side wall of the operating table (100); The arc-shaped rotating plate (720) is rotatably arranged on the extension portion outside the arc-shaped baffle (710), and the torsion spring (730) is sleeved on the rotating shaft of the arc-shaped rotating plate (720), and the two ends of the torsion spring (730) are respectively connected to the bottom of the rotating shaft and the extension portion of the arc-shaped rotating plate (720).

8. The sustained-release drug compression molding device according to claim 7, characterized in that: A rolling wheel (721) is provided at one end of the arc-shaped rotating plate (720) away from the rotating shaft.

9. The sustained-release drug compression molding device according to claim 7, characterized in that: The bottom of the material guiding device (700) is provided with a receiving bucket.