Female multi-effect cleaning wet tissue and preparation method thereof

Abstract

The invention provides a multi-effect cleaning wet tissue for women and a preparation method thereof, and belongs to the technical field of care products, the preparation method comprises the following steps: S1, uniformly mixing a chamomile extract, a camellia extract, lactic acid, a stabilizer, a preservative, an antibacterial agent and deionized water to obtain a wet tissue liquid; and S2, soaking dispersible wood pulp base cloth into the wet tissue liquid to fully absorb the wet tissue liquid, and packaging to obtain the multi-effect cleaning wet tissue for women. The invention provides a multi-effect cleaning wet tissue for women and a preparation method of the multi-effect cleaning wet tissue. The multi-effect cleaning wet tissue has multiple effects of cleaning, inhibiting bacteria, removing odor, relieving pruritus and the like.

Description

Technical Field

[0001] The invention relates to the technical field of care products, and in particular to a multi-effect cleaning wet wipe for women and a preparation method thereof. Background Art

[0002] With the improvement of living standards, people are paying more and more attention to personal hygiene. In particular, the improvement of modern women's concept of private care and the fast-paced work and life in modern times have made the demand for a product that can conveniently and effectively clean and care for private parts increasingly prominent.

[0003] There are many kinds of female private care products on the market, such as the patent with publication number CN107137299A, which is entitled a patent for a special female care wet wipe and a method for preparing the same. It discloses the introduction of persimmon extract into the emulsion of female care wet wipes, and uses the advantage of the rich Vc content of persimmon to block the process of protein and lipid oxidation into smelly ammonia, which fundamentally inhibits the generation of odor. However, the cause of odor in female private parts usually also includes the excessive number of Gardnerella, whose metabolites cause corresponding changes in the biochemical composition of vaginal secretions, and an increase in amine substances. Amine substances can increase vaginal secretions and have a bad smell. It only inhibits the generation of odor, and cannot fundamentally solve the problems of skin discomfort and itching caused by Gardnerella at the same time. Therefore, it is necessary to provide a female multi-effect cleaning wet wipe and a method for preparing the same to solve the problems existing in the above-mentioned prior art. Summary of the invention

[0004] In view of this, the present invention provides a multi-effect cleaning wet wipe for women and a preparation method thereof, which can simultaneously achieve multiple effects such as cleaning, antibacterial and deodorizing, and alleviating itching.

[0005] To achieve the above object, the present invention provides a method for preparing a multi-effect cleaning wet wipe for women, comprising the following steps: S1. Mix chamomile extract, camellia extract, lactic acid, stabilizer, preservative, antibacterial agent and deionized water to obtain wet wipes liquid; S2, immersing the flushable wood pulp base cloth into the wet wipes liquid to fully absorb the wet wipes liquid, and packaging the cloth to obtain the multi-effect cleaning wet wipes for women.

[0006] Optionally, the weight ratio of the flushable wood pulp base cloth to the wet wipes liquid is 1:2~2.2.

[0007] Optionally, the wet wipes liquid includes the following raw materials in weight percentage: 0.0001~0.0003% chamomile extract, 0.0001~0.0003% camellia extract, 0.001~0.0015% lactic acid, 0.01~0.02% stabilizer, 0.5~0.6% preservative, 0.301~0.353% antibacterial agent, and the weight percentage of deionized water plus the weight percentage of the above components add up to 100%.

[0008] Optionally, the stabilizer is disodium ethylenediaminetetraacetate.

[0009] Optionally, the preservative is benzalkonium chloride and polyaminopropyl biguanide solution.

[0010] Optionally, the weight percentage of the benzalkonium chloride is 0.1-0.15%; the weight percentage of the polyaminopropyl biguanide solution is 0.4-0.45%.

[0011] Optionally, the concentration of the polyaminopropyl biguanide in the polyaminopropyl biguanide solution is 20%.

[0012] Optionally, the antibacterial agent is phenoxyethanol and ethylhexylglycerin.

[0013] Optionally, the weight percentage of the phenoxyethanol is 0.3-0.35%; the weight percentage of the ethylhexylglycerin is 0.001-0.003%.

[0014] In order to achieve the above-mentioned purpose, the present invention also provides a multi-effect cleansing wet wipe for women.

[0015] The above technical solution of the present invention includes at least the following beneficial effects: The wet wipes of the present invention use chamomile extract and camellia extract together with lactic acid and other components to maintain the weakly acidic environment of the female private parts, exert the antibacterial effect of the natural defense mechanism of the female private parts, inhibit the growth of harmful bacteria such as Gardnerella, protect the stability of beneficial bacteria, and remove dirt and excess secretions on the surface of the female private parts, thereby improving the cleaning ability of the wet wipes. On the other hand, in combination with antibacterial agents, the cleaning and wiping rate of Escherichia coli, Staphylococcus aureus, Candida albicans, and odor-producing bacteria Gardnerella is as high as 99.9% or more, and the effect of removing odor from the root is achieved by removing the odor-producing bacteria Gardnerella.

[0016] In addition, the stabilizer used in the present invention promotes the effects of chamomile extract and camellia extract. Chamomile extract has anti-inflammatory and soothing effects, which can relieve discomfort in the private parts caused by inflammation and the like. Camellia extract also enhances moisturizing ability, promotes soft and smooth skin, and helps the skin recover after wiping stimulation. The flushable wood pulp base cloth used in the present invention is soft, non-irritating to mucous membranes and skin, has strong absorbency for wet wipes liquid, is evenly distributed, has high flushability, and is highly degradable in a natural environment.

[0017] The female multi-effect cleansing wet wipes provided by the present invention can be widely used in home, travel, business trip and other occasions, and are suitable for cleaning and care during menstrual period, hemorrhoid period, and before and after intimacy, providing a safe, gentle, convenient and multi-effect private parts cleaning and care solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a test report on the cleaning performance of the multi-effect cleaning wipes for women in the embodiment of the present invention; Figure 2 This is a test report on the performance of the multi-effect cleaning wipes for women in removing Gardnerella in the embodiments of the present invention; Figure 3 This is a test report on the performance of the multi-effect cleaning wipes for women in the embodiments of the present invention in removing Escherichia coli, Staphylococcus aureus and Candida albicans. DETAILED DESCRIPTION

[0019] To make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the following will be combined with the appended drawings of the embodiments of the present invention. Figures 1 to 3 , the technical scheme of the embodiment of the present invention is clearly and completely described. Obviously, the described embodiment is a part of the embodiment of the present invention, not all of the embodiments. Based on the described embodiment of the present invention, all other embodiments obtained by ordinary technicians in this field belong to the scope of protection of the present invention.

[0020] Example 1 Take the following components in weight percentage: 0.0001% chamomile extract, 0.0001% camellia extract, 0.001% lactic acid, 0.01% disodium ethylenediaminetetraacetic acid, 0.1% benzalkonium chloride, 0.4% polyaminopropyl biguanide solution, the concentration of polyaminopropyl biguanide in the polyaminopropyl biguanide solution is 20%, 0.3% phenoxyethanol, 0.001% ethylhexylglycerol, and the weight percentage of deionized water plus the weight percentage of the above components is 100%. The above components are mixed evenly in a GMP clean production workshop to obtain wet wipes liquid.

[0021] The flushable wood pulp base fabric is immersed in wet wipes liquid, and the weight ratio of the wet wipes liquid to the flushable wood pulp base fabric is 1:2.2. The flushable wood pulp base fabric absorbs the wet wipes liquid, and is packaged to obtain a female multi-effect cleaning wet wipe.

[0022] Example 2 Take the following components in weight percentage: 0.0003% chamomile extract, 0.0001% camellia extract, 0.0015% lactic acid, 0.01% disodium ethylenediaminetetraacetic acid, 0.15% benzalkonium chloride, 0.4% polyaminopropyl biguanide solution, 0.35% phenoxyethanol, 0.001% ethylhexylglycerol, and add the weight percentage of deionized water to the weight percentage of the above components to make 100%. The above components are mixed evenly in a GMP clean production workshop to obtain wet wipes liquid.

[0023] The flushable wood pulp base fabric is immersed in wet wipes liquid, and the weight ratio of the wet wipes liquid to the flushable wood pulp base fabric is 1:2. The flushable wood pulp base fabric absorbs the wet wipes liquid, and is packaged to obtain a female multi-effect cleaning wet wipes.

[0024] Example 3 Take the following components in weight percentage: 0.0001% chamomile extract, 0.0003% camellia extract, 0.001% lactic acid, 0.02% disodium ethylenediaminetetraacetic acid, 0.1% benzalkonium chloride, 0.45% polyaminopropyl biguanide solution, 0.3% phenoxyethanol, 0.003% ethylhexylglycerol, and add the weight percentage of deionized water to the weight percentage of the above components to make 100%. The above components are mixed evenly in a GMP clean production workshop to obtain wet wipes liquid.

[0025] The flushable wood pulp base fabric is immersed in wet wipes liquid, and the weight ratio of the wet wipes liquid to the flushable wood pulp base fabric is 1:2.2. The flushable wood pulp base fabric absorbs the wet wipes liquid, and is packaged to obtain a female multi-effect cleaning wet wipe.

[0026] Example 4 Take the following components in weight percentage: 0.0002% chamomile extract, 0.0002% camellia extract, 0.0013% lactic acid, 0.015% disodium ethylenediaminetetraacetic acid, 0.12% benzalkonium chloride, 0.43% polyaminopropyl biguanide solution, 0.32% phenoxyethanol, 0.002% ethylhexylglycerol, and add the weight percentage of deionized water to the weight percentage of the above components to make 100%. The above components are mixed evenly in a GMP clean production workshop to obtain wet wipes liquid.

[0027] The flushable wood pulp base fabric is immersed in wet wipes liquid, and the weight ratio of the wet wipes liquid to the flushable wood pulp base fabric is 1:2.1. The flushable wood pulp base fabric absorbs the wet wipes liquid, and is packaged to obtain a female multi-effect cleaning wet wipe.

[0028] The wet wipes prepared in Examples 1 to 4 were subjected to performance tests, mainly including cleaning performance and sterilization and deodorization performance.

[0029] 1. Testing of cleaning performance Entrust relevant testing institutions to test the cleaning performance and issue a test report. Figure 1 .

[0030] Testing basis: “Evaluation of Cosmetic Efficacy (ⅩⅢ) — Consumer Usage Test” published by Liu Weiyi et al. in Daily Chemical Industry.

[0031] Through a consumer questionnaire, relevant comments on the product were collected from 34 healthy female subjects after using the test product for 1 day under normal conditions to evaluate the cleaning efficacy of the product.

[0032] Product usage is shown in Table 1: Table 1 Product Usage

[0033] The test method is self-assessment by the subjects, that is, a questionnaire survey is conducted after using the product for 1 day to evaluate the feelings after using the product: Evaluation indicators and scoring criteria are shown in Table 2 Table 2 Evaluation indicators and scoring criteria of the questionnaire survey

[0034] Data analysis The binomial distribution method was used for statistical analysis, and the expected value of the degree of recognition was set at 60% (the proportion of people with a score of ≥4 points). The 95% confidence interval was used to test the statistical significance of the survey questions: if the significant P value is less than 0.050, it means there is a significant difference. (** indicates an extremely significant difference, P<0.010: * indicates a significant difference, 0.010≤P<0.050: ns indicates no significant difference, P≥0.050) Result judgment basis: Questionnaire conclusion: When the distribution of the subjects' self-assessment questionnaire's recognition of cleaning-related questions is significantly higher than the expected value of 60% (P<0.050), the claim of the product's "cleaning" efficacy can be supported.

[0035] Test conclusion: ①Sensory evaluation: Based on the evaluation of all subjects (N=34), after using the samples for 1 day, the subjects agreed that the product width is appropriate, the product thickness is appropriate, the product material is soft and comfortable, the product is not easy to be damaged when used, the product is just the right humidity when used, the hands do not get dirty when using the product, the stickiness of the skin is reduced after using the wet toilet paper, the stickiness of the skin is significantly reduced compared with ordinary toilet paper, the wet toilet paper can better reduce the stickiness of the skin compared with ordinary toilet paper, the skin feels comfortable, the skin comfort is significantly improved compared with ordinary toilet paper, and the wet toilet paper can better improve skin comfort compared with ordinary toilet paper.

[0036] ②Efficacy evaluation: Based on the evaluation of all subjects (N=34), after using the samples for 1 day, the subjects agreed that after using the wet toilet paper, the skin is cleaned, blood stains remaining on the skin can be cleaned, the skin cleanliness is significantly improved compared with ordinary toilet paper, the wet toilet paper has a better cleaning effect than ordinary toilet paper, the odor caused by the menstrual period is reduced, the skin odor is significantly reduced compared with ordinary toilet paper, the wet toilet paper can better eliminate odor compared with ordinary toilet paper, the skin itching caused by the menstrual period is reduced, the skin itching is significantly relieved compared with ordinary toilet paper, and the wet toilet paper can relieve skin itching compared with ordinary toilet paper.

[0037] ③Safety evaluation: Based on the evaluation of all subjects (N=34), after using the sample for 1 day, the subjects agreed that there was no discomfort in the application area after using the product.

[0038] ④Conclusion: Based on the results of this consumer test, the claim about the product’s “cleaning” efficacy can be supported.

[0039] It can be seen that the female multi-effect cleansing wet wipes prepared by the present invention have strong cleaning ability and can relieve itching.

[0040] 2. Test of sterilization performance Entrust relevant testing institutions to conduct testing and issue test reports. Sterilization test reports can be found at Figure 2 , Figure 3 .

[0041] 1. Test the sterilization performance of Gardnerella, the source of female private odor Test bacteria: Gardnerella vaginalis Bacterial inoculation concentration: 1.0x10 6 ~5.0x10 6 CFU / ml Carrier: Two simulated human skin models, soaked in 75% alcohol for 30 minutes, removed and dried before use. (Size: 225*155mm, thickness: silicone thickness ≥1.3cm, appearance thickness 2cm) Test steps: (1) Prepare the required bacterial suspension.

[0042] (2) Inoculate the carrier (take 0.1 ml of bacterial solution and spread it evenly on the carrier). Inoculate 2 carriers with each bacterial strain.

[0043] (3) The inoculated carrier was dried at room temperature for 15 minutes.

[0044] (4) Take a sterile cotton swab and moisten it with sterile saline, then smear it on the surface of a carrier for collection. After collection, add the cotton swab to 10 ml sterile saline and perform subsequent plate live bacteria count. The result is counted as A CFU cotton swab.

[0045] (5) Take another carrier and wipe it three times in the same direction, one sheet at a time.

[0046] (6) After swabbing, the carrier is collected according to step 4, and the result is counted as C CFU / swab.

[0047] (7) The above test was performed in three parallel groups.

[0048] (8) Calculation results The erasure rate of each parallel is calculated according to the following formula, and the final result is expressed as the arithmetic mean of the three parallel results, and the result is rounded to one decimal place.

[0049] Calculation formula: Erasure rate % = (AC) / Ax100% Where: A: Colony count of control group, CFU / cotton swab C: colony count of the test group, CFU / cotton swab The test results are shown in Table 3. Table 3 Erasure rate of Gardnerella vaginalis

[0050] Depend on Figure 2 As shown in Table 3, the erasing rate of vaginal Gardnerella by the female multi-effect cleansing wipes prepared by the present invention can reach 99.9%, and the effect of fundamentally removing odor is achieved by removing the odor-producing bacteria Gardnerella.

[0051] 2. Test the sterilization performance of conventional bacteria Test bacteria: Escherichia coli, Staphylococcus aureus, Candida albicans Bacterial inoculation concentration: 3.1x10 7 ~6.8x10 7 CFU / ml Carrier: A simulated human skin model with a size of 5×5cm Test steps: See the above test steps for the bactericidal performance of Gardnerella vaginalis The test results are shown in Table 4 Table 4 Erasure rates of Escherichia coli, Staphylococcus aureus and Candida albicans

[0052] Depend on Figure 3As shown in Table 4, the erasing rate of the female multi-effect cleansing wipes prepared by the present invention for Escherichia coli, Staphylococcus aureus and Candida albicans can reach 99.9%, and the antibacterial effect on harmful bacteria is obvious.

[0053] The above are preferred embodiments of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A method for preparing a multi-effect cleaning wet wipe for women, characterized in that: The following steps are involved: S1. Mix chamomile extract, camellia extract, lactic acid, stabilizer, preservative, antibacterial agent and deionized water to obtain wet wipes liquid; S2, immersing the flushable wood pulp base cloth into the wet wipes liquid to fully absorb the wet wipes liquid, and packaging the cloth to obtain the multi-effect cleaning wet wipes for women.

2. The method for preparing the multi-effect cleansing wipes for women according to claim 1, characterized in that: The weight ratio of the flushable wood pulp base cloth to the wet wipes liquid is 1:2~2.

2.

3. The method for preparing the multi-effect cleansing wipes for women according to claim 1, characterized in that: The wet wipes liquid comprises the following raw materials in percentage by weight: 0.0001-0.0003% chamomile extract, 0.0001-0.0003% camellia extract, 0.001-0.0015% lactic acid, 0.01-0.02% stabilizer, 0.5-0.6% preservative, 0.301-0.353% antibacterial agent, and the weight percentage of deionized water plus the weight percentage of the above components add up to 100%.

4. The method for preparing the multi-effect cleansing wet wipes for women according to claim 1, characterized in that: The stabilizer is disodium ethylenediaminetetraacetate.

5. The method for preparing the multi-effect cleansing wet wipes for women according to claim 1, characterized in that: The preservatives are benzalkonium chloride and polyaminopropyl biguanide solution.

6. The method for preparing the multi-effect cleansing wet wipes for women according to claim 5, characterized in that: The weight percentage of the benzalkonium chloride is 0.1-0.15%; the weight percentage of the polyaminopropyl biguanide solution is 0.4-0.45%.

7. The method for preparing the multi-effect cleansing wet wipes for women according to claim 6, characterized in that: The concentration of the polyaminopropyl biguanide in the polyaminopropyl biguanide solution is 20%.

8. The method for preparing the multi-effect cleansing wet wipes for women according to claim 1, characterized in that: The antimicrobial agents are phenoxyethanol and ethylhexylglycerin.

9. The method for preparing the multi-effect cleansing wet wipes for women according to claim 8, characterized in that: The weight percentage of the phenoxyethanol is 0.3-0.35%; the weight percentage of the ethylhexylglycerin is 0.001-0.003%.

10. A feminine multi-effect cleansing wet wipe obtained by the preparation method of the feminine multi-effect cleansing wet wipe according to any one of claims 1 to 9.

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