Preparation method and application of mild, moistening and anti-allergy composition

Through the preparation method of a mildly moisturizing and anti-allergic composition, it solves the problem that existing skin care products cannot meet the moisturizing needs of dry and mixed-dry skin in cold and dry environments, and achieves product uniformity and stability, with excellent It has excellent moisturizing, nourishing and anti-allergic effects and is suitable for industrial production.

CN119326690APending Publication Date: 2025-01-21ZHEJIANG SHOUXIANGU PHARMA CO LTD +2
View PDF 3 Cites 0 Cited by

Patent Information

Application Number
CN202411308707.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-19
Publication Date
2025-01-21

AI Technical Summary

Technical Problem

Existing skin care products are difficult to effectively meet the moisturizing and moisturizing needs of people with dry and mixed dry skin in the northern region in cold and dry winters, and the uniformity and stability of the products are insufficient, so there are safety issues.

Method used

A method for preparing a mildly moisturizing and anti-allergic composition is adopted, which includes subjecting phase A raw materials, phase B raw materials and phase C raw materials through specific homogenization, stirring and filtration steps to form emulsified particles with good compatibility and stability. . The specific steps include: homogenize phase A raw materials, add phase B raw materials and raise the temperature and keep it warm, then lower the temperature and add phase C raw materials, stir and filter.

Benefits of technology

It achieves the uniformity and stability of the composition, has excellent moisturizing, moisturizing and anti-allergic effects, is suitable for preparing products such as facial masks, lotions, essences and creams, has low cost, is suitable for industrial production, and improves user experience and Product storage stability.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure HDA0005050016580000011
    Figure HDA0005050016580000011
  • Figure HDA0005050016580000012
    Figure HDA0005050016580000012
  • Figure HDA0005050016580000021
    Figure HDA0005050016580000021
Patent Text Reader

Abstract

The invention relates to the field of A61K8 / 00, in particular to a preparation method and application of a mild, moistening and anti-allergy composition, the method is simple, the provided mild, moistening and anti-allergy composition is uniform in emulsified particle, high in product safety and stability and good in compatibility, the composition is endowed with efficient moisturizing, moistening and anti-allergy effects by cooperating with an A-phase raw material and a B-phase raw material in a system, and the composition is suitable for being applied to the field of cosmetics. The product is smooth and fine in touch, mild and non-irritating, high in user experience, suitable for being used by people with dry and mixed slightly dry skin in northern areas in winter, capable of being directly prepared into mild moisturizing anti-allergy repairing products such as masks, emulsions, essence and face cream or added, low in cost and suitable for industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the field of A61K8 / 00, and in particular to a preparation method and application of a mild, moisturizing and anti-allergic composition. Background Art

[0002] In the field of skin care products, moisturizing is the most basic part of various functions, and it is an important prerequisite for making the skin hydrated, shiny, elastic and firm. According to the water content of the skin's stratum corneum, the amount of sebum secretion and the skin's reactivity to external stimuli, the skin can be divided into neutral skin, dry skin, oily skin, mixed skin and sensitive skin. Mixed skin can be further divided into mixed dry skin and mixed oily skin. Skin care products will show obvious differences in effect depending on the user's skin condition or the climatic conditions of the area. For people with dry and mixed dry skin in northern regions, especially when used in cold and dry winters, the choice of skin care products is crucial.

[0003] Chinese patent CN106511253A discloses a whitening, moisturizing and nourishing facial mask cream and a preparation method thereof, which uses lotus root, white fungus, hydrolyzed collagen, pearl powder, mung bean, vitamin E and the like as main raw materials, so that the provided facial mask cream has certain whitening and moisturizing effects. However, the raw materials contain a variety of different plant ingredients, and the uniform stability of the facial mask cream particles cannot be effectively guaranteed, which may cause safety problems in use and cannot meet the actual use needs of people with dry and mixed dry skin in northern regions in the cold and dry winter; Chinese patent CN108030745A discloses a night deep moisturizing facial mask, which uses glycerin, olive oil, propolis, urea, sodium hyaluronate, tocopherol acetate and pearl powder as main raw materials. Although it can be used for hand care in dry climates, its moisturizing and nourishing effect when used on the face needs to be further improved. Chinese patent CN105902456A discloses a Prunus armeniaca and Eucommia ulmoides moisturizing mask and a preparation method thereof, which mainly improves the moisturizing effect and skin anti-aging performance by combining multiple plant extracts with nutrients, but the absorption effect and user experience of the mask need to be further improved. Summary of the invention

[0004] In order to solve the above problems, the present invention provides a method for preparing a mild moisturizing and anti-allergic composition. The method is simple, the emulsified particles in the composition product are uniform, the product system is stable, the compatibility is good, it is mild and non-irritating, and it has excellent moisturizing, nourishing and anti-allergic effects. It can be directly or added to prepare mild moisturizing and anti-allergic repair products such as facial masks, lotions, essences, and facial creams. The method has low cost and is suitable for industrial production, which has high practical application value.

[0005] In one aspect, the present invention provides a method for preparing a mild moisturizing anti-allergic composition, which comprises at least the following preparation steps:

[0006] (1) Add the raw materials of phase A into the preparation pot and homogenize;

[0007] (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 70-90° C. and keeping it warm for 20-30 min to obtain a mixture;

[0008] (3) Cool the mixture to 30-50°C, add the C phase raw material, stir for 15-20 minutes, and then filter the mixture to obtain the product.

[0009] As a preferred technical solution, in the step (1), the raw materials of phase A include 85-95 parts of deionized water, 0.01-0.05 parts of disodium ethylenediaminetetraacetate, and 0.05-0.12 parts of carbomer, by weight.

[0010] Preferably, the step (1) is specifically as follows: deionized water and disodium edetate are added into a preparation pot, the bottom homogenizer is turned on at 15-20 Hz, and the non-agglomerated carbomer is slowly sprinkled onto the vortex of the liquid surface, and the carbomer is homogenized for 10-20 minutes until the dispersion is uniform and there are no white lumps, the homogenizer is turned off, the internal and external stirring is turned on at 20 Hz, and heating is started.

[0011] Preferably, the viscosity of the carbomer (temperature is 25°C, pH value = 7.5, 0.5wt%) is 4000-11000cP; preferably, the model of the carbomer is 981NF, 71GNF, 971P NF; Preferably, the model of the carbomer is 981NF and 971P NF combination, preferably, the 981NF and The mass ratio of 971P NF is (1-2): (4-6). 981NF and 971P NF was purchased from The Lubrizol Corporation, USA.

[0012] During the research process, the present application found that the viscosity and structure of carbomer affect the uniformity of emulsified particles and the dispersion stability of the system, and thus have a great influence on the efficacy of the mild moisturizing anti-allergic composition. In the present application, carbomer with a viscosity of 4000-11000 cP is used, especially the model of 981NF and The carbomer of 971P NF, in combination with disodium edetate, effectively improves the dispersion stability of each component in the system, prolongs the use time of the mild moisturizing anti-allergic composition, and makes the mild moisturizing anti-allergic composition have good compatibility and suitable viscosity, improves storage stability, is mild and non-irritating, and ensures that the mild moisturizing anti-allergic composition has high moisturizing effect while not being sticky, greatly improving the user experience. Further, by controlling the process conditions, the technical problem that the color of the composition tends to darken after being placed at high temperature, affecting the adaptability of the formula, is solved.

[0013] As a preferred technical solution, in the step (2), the raw material of phase B includes at least 1-3 parts of methyl propanediol, 1-4 parts of polyglycerol ether, 0.01-0.1 parts of hydrolyzed sclerotium gum (SCLEROTIUM ROLFSSII), and 0.01-0.1 parts of xanthan gum, by weight. Preferably, the glycerol polyether is selected from one or more combinations of polyglycerol ether 10, polyglycerol ether 26, polyglycerol ether 12, polyglycerol ether 18, and polyglycerol ether 20. Preferably, the polyglycerol ether is polyglycerol ether 26, and the model of the polyglycerol ether is EG-1, which is purchased from Hai'an Petrochemical Plant. The brand of the hydrolyzed sclerotium gum (SCLEROTIUM ROLFSSII) is Bioeven HSG, which comes from Guangzhou Yiwan.

[0014] Based on the system of the present invention, by using the above-mentioned weight parts of polyglycerol ether, methyl propanediol, xanthan gum and hydrolyzed sclerotium gum, the dispersion compatibility of the composition system is effectively improved while improving the moisturizing effect of the composition, especially by using EG-1 type polyglycerol ether 26 in combination with a specific type of carbomer in component A, the mild moisturizing and anti-allergic composition has suitable fluidity and viscosity, and the composition has a smooth and delicate touch, avoiding the greasy and sticky skin feel caused by the use of a large amount of glycerin in existing moisturizing products, and can be directly or added to prepare mild moisturizing and anti-allergic repair products such as facial masks, emulsions, essences, and facial creams, and has high practical application value.

[0015] As a preferred technical solution, in the step (3), the raw materials of phase C include at least 0.5-1.2 parts of a repairing component, 0.01-0.2 parts of a soothing component, 0.5-2 parts of a moisturizing composition, and 1.0-1.5 parts of a plant extract, by weight.

[0016] As a preferred technical solution, the moisturizing composition includes isoprene glycol, caprylyl glycol, 1,2-hexanediol, p-hydroxyacetophenone, and dipropylene glycol.

[0017] The model of the moisturizing composition is HT-5688, which comes from Shanghai Haotai.

[0018] As a preferred technical solution, the repairing ingredient is selected from one or a combination of panthenol, inositol, composite hyaluronic acid, and ectoine; preferably, the repairing ingredient is a combination of panthenol, inositol, composite hyaluronic acid, and ectoine; preferably, the mass ratio of panthenol, inositol, composite hyaluronic acid, and ectoine is 0.5:0.1:(0.2-0.3):(0.01-0.1), so that the provided mild moisturizing and anti-allergic composition has significantly improved moisturizing, nourishing, and repairing effects, promotes the skin's effective absorption of the effective ingredients, and makes the skin smooth, shiny, and elastic.

[0019] The model of the composite hyaluronic acid is Tiansheng 7D-HA, which comes from Shandong Tiansheng.

[0020] In existing skin care products, moisturizing ingredients are mainly alcohol moisturizers such as glycerin and butylene glycol. Hyaluronic acid compounds are introduced into some skin care products to improve the hydrating and moisturizing effects. However, on the one hand, the large amount of glycerin used can easily make the skin care products feel greasy and have a noticeable ethanol smell, which reduces the user experience. On the other hand, the synergistic moisturizing effect of hyaluronic acid, glycerin and butylene glycol is not obvious. Based on the system of the present invention, by adopting the HT-5688 moisturizing composition, the synergistic effect with the inositol, composite hyaluronic acid and ectoine in the repair ingredients can be maximized, which not only moisturizes the skin surface, but also can penetrate into the skin to achieve deep moisturizing effect, so that the composition can still maintain a good active state under extreme environments such as high temperature, high salt and strong ultraviolet rays, and meet the actual use needs of people with dry and mixed dry skin in northern regions in cold and dry winter.

[0021] As a preferred technical solution, the soothing ingredient is selected from one or a combination of papain, allantoin, and sunflower stem cells; preferably, the soothing ingredient is sunflower stem cells, which are derived from Shanghai Tongyi Chemical, so that the provided mild moisturizing anti-allergic composition has outstanding soothing and sedative effects and anti-aging effects, relieves skin irritation and allergies, promotes skin microcirculation, and is beneficial to human health;

[0022] As a preferred technical solution, the plant extracts include chrysanthemum extract, ganoderma lucidum extract, kava extract, and turmeric extract. Preferably, the mass ratio of chrysanthemum extract, ganoderma lucidum extract, kava extract, and turmeric extract is 0.01:0.01:(0.5-1.2):(0.15-0.3).

[0023] The turmeric extract (Turmericgel) comes from Shanghai Ronghai Biological; the kava extract (kava extract UP) comes from Shanghai Enkai; the chrysanthemum extract and ganoderma lucidum extract both come from Jinhua Shouxiangu Pharmaceutical Co., Ltd.

[0024] The main active substances in turmeric extract are curcumin and turmeric ketone, which have the effects of lowering blood pressure, lowering blood lipids, promoting bile secretion, antibacterial, anti-inflammatory and antioxidant. The chrysanthemum extract can scavenge active oxygen free radicals, and has certain effects on inhibiting tumors, delaying aging and enhancing human immunity. The main active ingredients of Ganoderma lucidum extract are amino acids, polypeptides, reducing sugars, polysaccharides, ergosterol, triterpenes, volatile oils, etc., which have significant anti-aging and anti-cancer activities, protect cardiovascular and cerebrovascular health, and improve human immunity. Kava pepper extract is rich in volatile oils, piperine, crude fat and various amide compounds. The presence of active ingredients such as piperine, feruloyl piperidines and piperitone makes it have significant and timely analgesic and antipruritic effects and good antioxidant effects, helping to remove aging substances that are prone to induce various skin problems, producing a soothing and calming effect, and can be used to relieve skin irritation and allergies.

[0025] As a preferred technical solution, in the step (3), the phase C raw material further comprises a stabilizing component in parts by weight; preferably, the stabilizing component is selected from one or a combination of chitosan, rhamnose, oat glucan, trehalose, hydrolyzed glycosaminoglycan, acetyl chitosan, and soluble proteoglycan; preferably, the stabilizing component is a combination of trehalose and acetyl chitosan; preferably, the mass ratio of trehalose to acetyl chitosan is (0.4-0.8):0.1. After a large number of experimental investigations, the present application found that when trehalose and acetyl glucosamine with a mass ratio of (0.4-0.8):0.1 are introduced into the system, the problem of poor antibacterial properties of the chrysanthemum, ganoderma lucidum, kava pepper, and turmeric extract composition in the system after long-term storage is solved, and the skin is effectively promoted to absorb turmeric ketones, triterpenes, piperine, piperitone, amino acids, and polypeptide active substances in the plant extracts, which greatly improves the skin condition and human health. At the same time, the stability of sunflower stem cells in the system is improved, so that the provided mild moisturizing and anti-allergic composition is highly compatible with the skin and can be stored for a long time, avoiding product safety issues.

[0026] As a preferred technical solution, the mass ratio of the repairing ingredient, soothing ingredient, moisturizing composition, plant extract and stabilizing ingredient is (0.8-1.2): (0.01-0.12): (0.8-1.5): (1.0-1.4): 0.6, so that the provided mild moisturizing and anti-allergic composition has very high product safety and stability. The components A and B phase raw materials in the synergistic system give the composition efficient moisturizing, nourishing and anti-allergic effects, smooth and delicate touch, mild and non-irritating, high user experience, and is especially suitable for use by people with dry and mixed dry skin in northern regions in cold and dry winters.

[0027] Another aspect of the present invention provides an application of a method for preparing a mild moisturizing anti-allergic composition, wherein the mild moisturizing anti-allergic composition is prepared by self-preparation or addition to prepare mild moisturizing anti-allergic repairing lotion, essence, facial mask and facial cream products.

[0028] Beneficial effects:

[0029] 1. The present invention provides a method for preparing a mild moisturizing and anti-allergic composition. The method is simple, the emulsified particles in the composition product are uniform, the product system is stable, the compatibility is good, it is mild and non-irritating, and it has excellent moisturizing, nourishing and anti-allergic effects. It can be directly or added to prepare mild moisturizing and anti-allergic repair products such as facial masks, lotions, essences, and facial creams. The method has low cost and is suitable for industrial production.

[0030] 2. In the present invention, carbomer with a viscosity of 4000-11000 cP is used, especially carbomer with a model of 981NF and The carbomer of 971P NF, in combination with disodium edetate, effectively improves the dispersion stability of each component in the system, prolongs the use time of the mild moisturizing anti-allergic composition, and makes the mild moisturizing anti-allergic composition have good compatibility and suitable viscosity, improves storage stability, is mild and non-irritating, and ensures that the mild moisturizing anti-allergic composition has high moisturizing effect while not being sticky, greatly improving the user experience. Further, by controlling the process conditions, the technical problem that the color of the composition tends to darken after being placed at high temperature, affecting the adaptability of the formula, is solved.

[0031] 3. In this application, by adopting the HT-5688 moisturizing composition, the synergistic effect with the inositol, complex hyaluronic acid and ectoine in the repair ingredients can be maximized, which not only moisturizes the skin surface, but also penetrates into the skin to achieve deep moisturizing effect, so that the composition can still maintain a good active state in extreme environments such as high temperature, high salt and strong ultraviolet rays, and meet the actual use needs of people with dry and mixed dry skin in northern regions in the cold and dry winter.

[0032] 4. By introducing trehalose and acetyl glucosamine in a mass ratio of (0.4-0.8):0.1, the problem of poor antibacterial properties of the chrysanthemum, ganoderma lucidum, kava pepper and turmeric extract composition after long-term storage in the system is solved, and the skin is effectively promoted to absorb turmeric ketones, triterpenes, piperine, piperitone, amino acids and polypeptide active substances in the plant extracts, which greatly improves the skin condition and human health. At the same time, the stability of sunflower stem cells in the system is improved, so that the provided mild moisturizing and anti-allergic composition is highly compatible with the skin and can be stored for a long time, avoiding product safety issues.

[0033] 5. By controlling the mass ratio of the repairing ingredient, soothing ingredient, moisturizing composition, plant extract and stabilizing ingredient to (0.8-1.2): (0.01-0.12): (0.8-1.5): (1.0-1.4): 0.6, the provided mild moisturizing and anti-allergic composition has high product safety and stability. The components A and B phase raw materials in the synergistic system give the composition efficient moisturizing, nourishing and anti-allergic effects, smooth and delicate touch, mild and non-irritating, and high user experience. It is especially suitable for use by people with dry and mixed dry skin in northern regions in cold and dry winters. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 This is a diagram showing the scavenging effect of chrysanthemum extract on DPPH free radicals.

[0035] Figure 2 This is the test result of chrysanthemum extract on macrophage-inflammatory factors.

[0036] Figure 3 This is a diagram showing the scavenging effect of Ganoderma lucidum extract on DPPH free radicals. DETAILED DESCRIPTION

[0037] Example 1

[0038] Embodiment 1 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, comprising the following preparation steps:

[0039] (1) Add the raw materials of phase A into the preparation pot and homogenize;

[0040] (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 80° C. and keeping it warm for 30 min to obtain a mixture;

[0041] (3) Cool the mixture to 40°C, add the C phase raw material, stir for 20 minutes, and then filter the mixture to obtain the product.

[0042] In terms of weight, the raw materials of phase A in step (1) include 90 parts of deionized water, 0.03 parts of disodium ethylenediaminetetraacetate, and 0.1 parts of carbomer. Step (1) is specifically as follows: deionized water and disodium ethylenediaminetetraacetate are added to a preparation pot, the bottom homogenizer is turned on at 20Hz, and carbomer without lumps is slowly sprinkled onto the vortex of the liquid surface, and the carbomer without lumps is homogenized for 20 minutes until the carbomer is evenly dispersed without white lumps, the homogenizer is turned off, the internal and external stirring is turned on at 20Hz, and heating is started.

[0043] The model of the carbomer is 981NF and 971P NF combination, the 981NF and The mass ratio of 971P NF is 1.5:5.

[0044] In terms of weight, the raw materials of phase B in step (2) include 2 parts of methyl propanediol, 2 parts of polyglycerol ether, 0.05 parts of hydrolyzed sclerotium gum (SCLEROTIUM ROLFSSII), and 0.05 parts of xanthan gum. The polyglycerol ether is polyglycerol ether 26, the model of the polyglycerol ether is EG-1, purchased from Haian Petrochemical Plant. The brand of the hydrolyzed sclerotium gum (SCLEROTIUM ROLFSSII) is Bioeven HSG, which comes from Guangzhou Yiwan.

[0045] In terms of weight, the raw materials of phase C in step (3) include 0.9 parts of a repairing component, 0.1 parts of a soothing component, 1.0 parts of a moisturizing composition, and 1.27 parts of a plant extract;

[0046] The moisturizing composition comprises isoprene glycol, caprylyl glycol, 1,2-hexanediol, p-hydroxyacetophenone and dipropylene glycol. The model of the moisturizing composition is HT-5688, which comes from Shanghai Haotai.

[0047] The repairing ingredients are a combination of panthenol, inositol, composite hyaluronic acid and ectoine; the mass ratio of panthenol, inositol, composite hyaluronic acid and ectoine is 0.5:0.1:0.25:0.05. The model of the composite hyaluronic acid is Tiansheng 7D-HA, which comes from Shandong Tiansheng.

[0048] The soothing ingredient is a combination of sunflower stem cells; sourced from Shanghai Tongyi Chemical.

[0049] The plant extracts include chrysanthemum extract, ganoderma lucidum extract, kava extract, and turmeric extract. The mass ratio of chrysanthemum extract, ganoderma lucidum extract, kava extract, and turmeric extract is 0.01:0.01:1:0.25. The turmeric extract (Turmericgel) is from Shanghai Ronghai Biological; the kava extract (kava extract UP) is from Shanghai Enkai; the chrysanthemum extract and ganoderma extract are both from Jinhua Shouxiangu Pharmaceutical Co., Ltd.

[0050] In terms of parts by weight, the phase C raw material in step (3) further includes 0.6 parts of a stabilizing component; the stabilizing component is a combination of trehalose and acetyl glucosamine; and the mass ratio of trehalose to acetyl glucosamine is 0.5:0.1.

[0051] Example 2

[0052] Example 2 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, and its specific implementation is the same as that of Example 1, except that it includes the following preparation steps:

[0053] (1) Add the raw materials of phase A into the preparation pot and homogenize;

[0054] (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 85° C. and keeping it warm for 20 min to obtain a mixture;

[0055] (3) Cool the mixture to 45°C, add the C phase raw material, stir for 20 minutes, and then filter the mixture to obtain the product.

[0056] Example 3

[0057] Example 3 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, and its specific implementation is the same as that of Example 1, except that it includes the following preparation steps:

[0058] (1) Add the raw materials of phase A into the preparation pot and homogenize;

[0059] (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 70° C. and keeping it warm for 30 min to obtain a mixture;

[0060] (3) Cool the mixture to 35°C, add the C phase raw material, stir for 20 minutes, and then filter the mixture to obtain the product.

[0061] Comparative Example 1

[0062] Comparative Example 1 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, and its specific implementation method is the same as that of Example 1, except that the model of the carbomer is Ultrez 10NF was purchased from Lubrizol Corporation, USA.

[0063] Comparative Example 2

[0064] Comparative Example 2 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, and its specific implementation method is the same as that of Example 1, except that the glycerol polyether is polyglycerol ether 10.

[0065] Comparative Example 3

[0066] Comparative Example 3 of the present invention provides a method for preparing a mild moisturizing anti-allergic composition, and its specific implementation is the same as that of Example 1, except that it includes the following preparation steps:

[0067] (1) Add the raw materials of phase A into the preparation pot and homogenize;

[0068] (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 90° C. and keeping it warm for 15 min to obtain a mixture;

[0069] (3) Cool the mixture to 20°C, add the C phase raw material, stir for 20 minutes, and then filter the mixture to obtain the product.

[0070] Performance Testing Methods

[0071] (1) Heat resistance: The compositions prepared in the examples and comparative examples of the present invention were placed at (40±2)°C for 24 h. If the compositions did not delaminate, precipitate, or have odor or discoloration after returning to room temperature (25°C), the heat resistance of the compositions was considered qualified. If the compositions did delaminate, precipitate, have odor or discoloration after returning to room temperature (25°C), the heat resistance of the compositions was considered unqualified.

[0072] (2) Cold resistance: The compositions prepared in the examples and comparative examples of the present invention were placed at (-5±2)°C for 24 h. If the compositions did not delaminate, precipitate, or have odor or discoloration after returning to room temperature (25°C), the cold resistance of the compositions was considered qualified. If the compositions did delaminate, precipitate, have odor or discoloration after returning to room temperature (25°C), the cold resistance of the compositions was considered unqualified.

[0073] project Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 Heat resistance qualified qualified qualified Failure Failure Failure Cold resistance qualified qualified qualified Failure qualified Failure

[0074] (3) The viscosity, pH and relative density of the composition provided in Example 1 were tested after being placed at 25° C. for 7 days, 40° C. for 7 days and −5° C. for 7 days. The results are shown in Table 2.

[0075] Table 2

[0076] Example 1 Small test 25℃,7d -5℃,7d 40℃,7d Viscosity (mpa·s) 267.4 185.9 192.6 PH 6.27 5.94 6.1 Relative density 1 1.01 1.01

[0077] (4) The viscosity, pH and relative density of the composition provided in Example 1 were tested after being placed at 50° C. for 0 days, 10 days, 20 days and 30 days, respectively. The results are shown in Table 3.

[0078] Table 3

[0079] Example 1 Pilot Day 0 10 days 20 days 30 days Viscosity (mpa·s) 267.4 / / / PH 6.27 6 6.27 6.08 Relative density 1 1.01 1.02 1.01

[0080] (5) The DPPH free radical scavenging test was performed on the chrysanthemum extract in the example. The test results are shown in Figure 1 , 2 .

[0081] (6) The Ganoderma lucidum extract in the example was tested for macrophage-inflammatory factors. The test results are shown in Figure 1 , 3 .

Claims

1. A method for preparing a mild moisturizing anti-allergic composition, characterized in that: The method comprises at least the following preparation steps: (1) Add the raw materials of phase A into the preparation pot and homogenize; (2) stirring the phase B raw material evenly and adding it to the phase A raw material, heating it to 70-90° C. and keeping it warm for 20-30 min to obtain a mixture; (3) Cooling the mixture to 30-50° C., adding the C-phase raw material, stirring for 15-20 minutes, and filtering the material to obtain the mixture; in terms of weight, the C-phase raw material in step (3) comprises at least 0.5-1.2 parts of a repairing component, 0.01-0.2 parts of a soothing component, 0.5-2 parts of a moisturizing composition, and 1.0-1.5 parts of a plant extract; the plant extract comprises chrysanthemum extract, ganoderma lucidum extract, kava extract, and turmeric extract.

2. The method for preparing a mild moisturizing anti-allergic composition according to claim 1, characterized in that: In parts by weight, the raw materials of phase A in step (1) include 85-95 parts of deionized water, 0.01-0.05 parts of disodium ethylenediaminetetraacetate, and 0.05-0.12 parts of carbomer.

3. The method for preparing a mild moisturizing anti-allergic composition according to claim 2, characterized in that: The step (1) is specifically as follows: deionized water and disodium edetate are added into a preparation pot, the bottom homogenizer is turned on at 15-20 Hz, and the non-agglomerated carbomer is slowly sprinkled onto the vortex of the liquid surface, and the carbomer is homogenized for 10-20 minutes until the carbomer is evenly dispersed without white lumps, the homogenizer is turned off, the internal and external stirring is turned on at 20 Hz, and heating is started.

4. The method for preparing a mild moisturizing anti-allergic composition according to claim 3, characterized in that: The viscosity of the carbomer is 4000-11000 cP.

5. The method for preparing a mild moisturizing anti-allergic composition according to claim 1, characterized in that: In terms of weight, the raw materials of phase B in step (2) include at least 1-3 parts of methyl propanediol, 1-4 parts of polyglycerol ether, 0.01-0.1 parts of hydrolyzed sclerotium gum, and 0.01-0.1 parts of xanthan gum.

6. The method for preparing a mild moisturizing anti-allergic composition according to claim 1, characterized in that: The moisturizing composition comprises isopentyl glycol, caprylyl glycol, 1,2-hexanediol, p-hydroxyacetophenone and dipropylene glycol.

7. The method for preparing a mild moisturizing anti-allergic composition according to claim 6, characterized in that: The repairing ingredient is selected from one or a combination of panthenol, inositol, composite hyaluronic acid and ectoine.

8. The method for preparing a mild moisturizing anti-allergic composition according to claim 6, characterized in that: The soothing ingredient is selected from one or a combination of papain, allantoin, and sunflower stem cells.

9. The method for preparing a mild moisturizing anti-allergic composition according to claim 1, characterized in that: In terms of parts by weight, the phase C raw material in step (3) also includes 0.4-1 parts of a stabilizing component.

10. An application of the method for preparing a mild moisturizing anti-allergic composition according to any one of claims 1 to 9, characterized in that: The mild moisturizing anti-allergic composition is used for repairing lotion, essence, facial mask and facial cream products.

Citation Information

Patent Citations

  • Moisturizing and moistening mask containing wild apricots and eucommia and preparation method thereof

    CN105902456A

  • Whitening and moisturizing facial mask cream and preparation method thereof

    CN106511253A

  • A deep-layer moistening mask for night use

    CN108030745A