The invention relates to a synergistic pesticidal composition containing Clothianidin and emamectin benzoate, and its application. The synergistic pesticidal composition is mainly applied in research and application on prevention and treatment of rice hopper and borer. The invention solves the defects of most organophosphorus nicotine products used in pesticides at present, and the results of experiments show that the composition has good effect of controlling Sogatella furcifera. The pesticidal composition comprises the following active ingredients: 0.1-50 wt% of Clothianidin and 50-0.1 wt% of emamectin benzoate, and comprises the balance consisting of auxiliary agents and a carrier. The pesticidal composition can be applied to control plant hopper, borer, aphid, leafhopper, thrip, cabbage caterpillar, diamondback moth, beet armyworm, prodenia litura and other Hemiptera, Coleoptera, Diptera and some Lepidoptera insects for rice, vegetables, fruit trees and other crops. The other insects comprise plant hopper, rice leaf roller, Chilo suppressalis, tobacco aphid, Myzus persicae, Pear psylla, whitefly and the like. The invention also discloses the application of the pesticidal composition in lepidoptera insects and piercing and sucking type insects of crops.