Antibacterial powder and preparation method thereof

Abstract

The invention provides antibacterial powder and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-30 parts of raw sanguisorba officinalis, 15-25 parts of coptis chinensis, 15-30 parts of golden cypress, 10-25 parts of raw rhubarb, 10-20 parts of bletilla striata, 15-25 parts of musk and 10-25 parts of pulvis fellis suis. The preparation method comprises the following steps: S1, peeling the musk, sterilizing, disinfecting, crushing and sieving to obtain musk powder; and S2, crushing and sieving the rest raw materials, adding the musk powder, and uniformly mixing. The antibacterial powder is used for trauma infection and wound healing, can wake up dormant cells, repair damaged cells, promote cell in-situ regeneration and tissue reduction and improve microcirculation, is strong in antibacterial effect, accelerates wound healing, is rapid in hemostasis and pain relief, can rapidly stop pain and bleeding, remove slough and promote tissue regeneration within 5-15 seconds, can heal fresh wounds within 24-48 hours, and does not leave scars after healing.

Description

Technical Field

[0001] The present invention relates to the field of Chinese medicinal materials, and in particular to an antibacterial powder and a preparation method thereof. Background Art

[0002] Ulcerative wounds usually present as deep damage to the skin or mucous membrane, accompanied by obvious necrotic tissue and exudate. When treating such wounds, the wounds must be cleaned and disinfected first, and combined with topical anti-infective drugs such as erythromycin ointment and fusidic acid cream, which can inhibit bacterial growth and promote wound healing. Astringent drugs such as zinc oxide solution can promote the drying of the erosion surface and reduce exudate.

[0003] Erosive wounds usually manifest as damage to the surface of the skin or mucous membrane, accompanied by symptoms such as exudate, redness, swelling and pain. When treating such wounds, it is necessary to first remove necrotic tissue and pus to create a good environment for wound healing. Then use normal saline to rinse to reduce the number of bacteria. Combined with topical anti-infective drugs: such as erythromycin ointment, levofloxacin ointment, etc., can inhibit bacterial growth and prevent the spread of infection. And drugs that promote granulation growth, such as epidermal growth factor, can promote the growth of granulation tissue in the wound and accelerate healing. For large and deep ulcer wounds, surgical repair may be required to promote healing and restore function.

[0004] For the treatment of the above-mentioned wounds or fresh wounds, it is particularly important to disinfect, sterilize and antibacterial the wounds, as well as promote wound healing. In the field of Western medicine, topical anti-infective drugs are needed for disinfection and sterilization, and drugs that promote wound healing are used for treatment; in the field of traditional Chinese medicine, such as golden powder, ice pen powder, scab powder, etc., can directly act on the wound surface, promote the repair and regeneration of local tissues, and also have antibacterial and anti-inflammatory, hemostatic and analgesic effects. Compared with Western medicine, Chinese medicine powder is easy to use, has comprehensive effects, and has few toxic and side effects. However, the Chinese medicine powder for treating wounds is not ideal for disinfection and sterilization, and the efficacy needs to be improved. Summary of the invention

[0005] The purpose of the present invention is to provide an antibacterial powder, which can awaken dormant cells, repair damaged cells, promote cell regeneration in situ and tissue reduction, improve microcirculation, accelerate wound healing, have strong antibacterial effect, stop bleeding and relieve pain quickly, can quickly stop pain and stop bleeding within 5-15 seconds, remove dead tissue and promote tissue regeneration, can heal fresh wounds within 24-48 hours, and will not leave scars after healing.

[0006] Another object of the present invention is to provide a method for preparing antibacterial powder, which has a simple and fast preparation process and low requirements on production equipment.

[0007] The present invention solves the technical problem by adopting the following technical solutions.

[0008] In one aspect, an embodiment of the present invention provides an antibacterial powder, comprising the following raw materials in parts by weight:

[0009] 15-30 parts of raw Sanguisorba officinalis, 15-25 parts of Coptidis rhizome, 15-30 parts of Phellodendron chinense, 10-25 parts of raw rhubarb, 10-20 parts of Bletilla striata, 15-25 parts of Musk, and 10-25 parts of pig gall powder.

[0010] In some embodiments of the present invention, the following raw materials are included by weight: 20 parts of raw Sanguisorba officinalis, 18 parts of Coptis chinensis, 20 parts of Phellodendron chinense, 20 parts of raw rhubarb, 15 parts of Bletilla striata, 18 parts of Musk, and 15 parts of pig gall powder.

[0011] In some embodiments of the present invention, the following raw materials are included by weight: 15 parts of raw Sanguisorba officinalis, 25 parts of Coptis chinensis, 15 parts of Phellodendron chinense, 10 parts of raw rhubarb, 20 parts of Bletilla striata, 25 parts of Musk, and 25 parts of pig gall powder.

[0012] On the other hand, an embodiment of the present invention provides a method for preparing an antibacterial powder, comprising:

[0013] S1, peeling the musk, sterilizing and disinfecting it, crushing and sieving it to obtain musk powder;

[0014] S2, crush the remaining raw materials separately, sieve them, add musk powder, and mix them evenly.

[0015] In some embodiments of the present invention, in steps S1 and S2, the mesh size of the sieving is 200 meshes.

[0016] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:

[0017] The antibacterial powder provided by the present invention uses raw sanguisorba officinalis, coptis root, phellodendron, raw rhubarb, bletilla striata, musk and pig gall powder as raw materials, has the effects of rapid hemostasis, astringency, pus drainage, skin growth and flesh growth, and has a good antibacterial effect on the wound surface. It can promote in situ cell regeneration, remove dead tissue and regenerate new muscles, and leave no scars after healing; it has strong antibacterial and wide range. It can stop pain and stop bleeding quickly, and can stop bleeding and stop pain quickly within 5-15 seconds; it is easy to use, and it directly acts on the wound surface, and has a direct repair effect on the skin of diabetic distal limbs that have stopped circulating, severe burn wounds, pressure sores (bedsores) wounds and various traumatic infection wounds, and can awaken dormant cells, repair damaged cells, promote in situ cell regeneration and tissue reduction, improve microcirculation, and accelerate wound healing. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is the wound image of case 1 before treatment;

[0020] Figure 2 This is the wound picture during treatment of Case 1;

[0021] Figure 3 This is the wound picture of case 1 after treatment;

[0022] Figure 4 This is the wound image of case 2 before treatment;

[0023] Figure 5 This is the wound picture during treatment of Case 2;

[0024] Figure 6 This is the wound picture of case 2 after treatment;

[0025] Figure 7 This is the wound image of case 3 before treatment;

[0026] Figure 8 This is the wound picture during treatment of Case 3;

[0027] Fig. 9 This is the wound picture of case 3 after treatment;

[0028] Fig.10 These are the wound pictures of Case 6 before, during and after treatment;

[0029] Fig.11 These are the wound pictures of Case 7 before, during and after treatment;

[0030] Fig.12 These are the wound pictures of Case 8 before, during and after treatment;

[0031] Fig.13 These are the wound pictures of Case 10 before, during and after treatment;

[0032] Fig.14 These are the wound pictures of Case 11 before, during and after treatment;

[0033] Fig.15 These are the wound pictures of Case 12 before, during and after treatment;

[0034] Fig.16 These are the wound pictures of Case 13 before, during and after treatment;

[0035] Fig.17 These are the wound pictures of Case 14 before, during and after treatment;

[0036] Fig.18 These are the wound pictures of Case 15 before, during and after treatment;

[0037] Fig.19 This is the discharge and admission status of some patients in clinical trials. DETAILED DESCRIPTION

[0038] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased commercially.

[0039] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments may be combined with each other. The present invention will be described in detail below with reference to specific embodiments.

[0040] The embodiment of the present invention provides an antibacterial powder, which comprises the following raw materials in parts by weight:

[0041] 15-30 parts of raw Sanguisorba officinalis, 15-25 parts of Coptidis rhizome, 15-30 parts of Phellodendron chinense, 10-25 parts of raw rhubarb, 10-20 parts of Bletilla striata, 15-25 parts of Musk, and 10-25 parts of pig gall powder.

[0042] More preferably, the following raw materials are included by weight: 20 parts of raw Sanguisorba officinalis, 18 parts of Coptis chinensis, 20 parts of Phellodendron chinense, 20 parts of raw rhubarb, 15 parts of Bletilla striata, 18 parts of Musk, and 15 parts of pig gall powder

[0043] More preferably, 15 parts of raw Sanguisorba officinalis, 25 parts of Coptis chinensis, 15 parts of Phellodendron chinense, 10 parts of raw rhubarb, 20 parts of Bletilla striata, 25 parts of Musk, and 25 parts of pig gall powder.

[0044] The raw materials used in the embodiments of the present invention have the following functions:

[0045] Raw Sanguisorba officinalis, i.e. the dried root of Sanguisorba officinalis, is a perennial herbaceous plant of the genus Sanguisorba in the family Rosaceae. (1) It has the effect of cooling blood and stopping bleeding: it contains substances such as tannins and polyphenols, which can strongly inhibit fibrinolytic enzymes and have a strong hemostatic function. It can be used to treat bleeding symptoms such as vomiting blood, epistaxis, hematemesis, hemoptysis, blood in the stool, metrorrhagia, postpartum hemorrhage, and heavy menstruation caused by blood heat. (2) It has the effect of clearing away heat and detoxifying: Sanguisorba officinalis contains rich active ingredients such as sanguisorbaside, sanguisorbaside, aglycone, ursolic acid, sanguisorbaside and sanguisorbaside A, which can clear heart fire and be used to treat irritability, restlessness, mouth sores, etc.; clear lung fire and be used to treat cough, asthma, dry cough with little sputum, sore throat, etc.; calm liver fire and be used to treat eye fatigue, dry eyes, red and swollen eyes, etc. In addition, it can also be used for symptoms such as sores, carbuncle, and hemorrhoids. (3) It has the effect of reducing swelling and healing sores: It is rich in flavonoids, and its aglycones are quercetin and kaempferol, and it also contains betulinic acid. It can be used to treat skin diseases such as eczema and vulvar itching, as well as trauma such as scalds and burns caused by water or fire. It has the effect of reducing swelling and healing sores on wounds, reducing symptoms such as exudation in the skin lesions, and can reduce tissue edema, allowing the wound to recover effectively in a relatively short period of time, and preventing more serious complications caused by abscess infection. (4) It has antibacterial and anti-inflammatory effects: It contains 4-tri-O-methylgallic acid, which has a significant resistance to a variety of pathogens such as Escherichia coli, Pseudomonas aeruginosa, and Salmonella paratyphi.

[0046] Coptis chinensis is cold in nature and bitter in taste. It enters the heart, spleen, stomach, liver, gallbladder, and large intestine meridians. The main effects of Coptis chinensis include: Clearing away heat and drying dampness: Coptis chinensis can clear the damp heat in the body, and has a good therapeutic effect on symptoms such as damp heat, vomiting and acid regurgitation, diarrhea, and jaundice. Purging fire and detoxifying: Coptis chinensis can purge the real fire in the body, and has a good effect on symptoms such as high fever and coma, hyperactivity of heart fire, vomiting and bleeding due to blood heat, red eyes, and toothache. In addition, Coptis chinensis can also detoxify, and has a good therapeutic effect on surgical diseases such as carbuncles and furuncles. Antibacterial and anti-inflammatory: Coptis chinensis contains a variety of alkaloids, such as berberine and coptisine, which have antibacterial and anti-inflammatory effects and can inhibit the growth and reproduction of a variety of bacteria.

[0047] Phellodendron chinense is the dried bark of the Rutaceae plant Phellodendron chinense, which has the effects of clearing away heat and dampness, purging fire and removing steam, detoxifying and curing sores. It is mainly used to treat damp-heat diarrhea, jaundice and red urine, vaginal itching, hot stranguria, beriberi, bone steaming, fatigue and fever, night sweats, spermatorrhea, sores, swelling and poison, eczema and wet sores. The specific effects are as follows:

[0048] Clearing away heat and drying dampness: Phellodendron chinense is bitter and cold in nature, which can clear away dampness and heat in the body. When used externally, it has a good alleviating effect on skin symptoms caused by dampness and heat, such as eczema and contact dermatitis. It can reduce moisture on the surface of the skin and promote the skin to return to a healthy state.

[0049] Insecticidal and antipruritic: Phellodendron chinense has the effect of killing insects and relieving itching. It can be used externally to treat skin itching, erythema, papules and other symptoms caused by diseases such as eczema and scabies. By applying Phellodendron chinense externally, these symptoms can be effectively alleviated and the quality of life of patients can be improved.

[0050] Reduce swelling and heal ulcers: Phellodendron chinense external application also has the effect of reducing swelling and heal ulcers. When the skin is infected by bacteria or trauma, local swelling and ulcers may occur. Phellodendron chinense can reduce swelling and promote the healing of ulcers, thereby accelerating the recovery process of the skin.

[0051] Heat-clearing and detoxification: Phellodendron chinense can clear away heat and toxicity in the body, and has a good therapeutic effect on skin symptoms caused by heat and toxicity when applied externally. It can reduce the heat on the surface of the skin and relieve pain and discomfort.

[0052] Raw rhubarb is the dried root and rhizome of Rheum palmatum, Rheum tanguticum or Rheum officinale, which belongs to the Polygonaceae family. It has the following effects:

[0053] Antibacterial and anti-inflammatory: When raw rhubarb is applied externally, the active ingredients it contains can inhibit the growth and reproduction of a variety of bacteria, thereby achieving antibacterial and anti-inflammatory effects. For skin diseases caused by bacterial infections such as skin ulcers and eczema, external use of raw rhubarb can reduce inflammatory reactions and promote wound healing.

[0054] Clearing away heat and drying dampness: Raw rhubarb is cold in nature. When applied externally, it can clear away dampness and heat from the skin surface, helping to improve symptoms such as skin redness and swelling, and toxin accumulation. For skin diseases caused by dampness and heat, such as eczema and tinea pedis, applying raw rhubarb externally can alleviate symptoms and promote recovery.

[0055] Activating blood circulation and removing blood stasis: When raw rhubarb is applied externally, its effect of activating blood circulation and removing blood stasis can promote local blood circulation and accelerate the dissipation of blood stasis. For symptoms such as skin congestion and pain caused by trauma, water and fire burns, etc., applying raw rhubarb externally can alleviate symptoms and promote recovery.

[0056] Reduce swelling and relieve pain: When raw rhubarb is applied externally, its effect of reducing swelling and relieving pain can reduce local swelling and pain. For swelling and pain caused by trauma, sprains, carbuncles, furuncles, etc., raw rhubarb can quickly relieve it.

[0057] Detoxification and skin regeneration: When raw rhubarb is applied externally, its detoxification and skin regeneration effect can promote wound detoxification, remove dead tissue and promote new tissue, thus accelerating wound healing. For wounds caused by skin infection, burns, scalds, etc., applying raw rhubarb externally can reduce the risk of infection and promote wound recovery.

[0058] Bletilla striata has the effects of astringing and stopping bleeding, reducing swelling and promoting tissue regeneration. It is mainly used to treat hemoptysis, hematemesis, maggot blood, blood in the stool, as well as symptoms such as traumatic bleeding, ulcer swelling, skin rupture, etc. The specific effects are as follows.

[0059] Astringent and hemostatic: The gelatinous components contained in Bletilla striata can shorten the coagulation time, accelerate the sedimentation rate of red blood cells, and promote red blood cell aggregation to form artificial thrombi, thereby repairing vascular defects and achieving the effect of hemostasis. Therefore, Bletilla striata can be used to treat various bleeding symptoms such as hemoptysis, hematemesis, and blood in the stool.

[0060] Reduce swelling and promote tissue regeneration: Bletilla striata can treat symptoms such as sores, bleeding, ulcers, carbuncle swelling, chapped hands and feet, and anal fissures. It can promote the repair and regeneration of skin, mucous membranes and other tissues and accelerate wound healing.

[0061] Antibacterial and anti-inflammatory: Bletilla striata also has certain antibacterial and anti-inflammatory effects, and can be used to treat skin infections, oral ulcers and other diseases.

[0062] Beauty and skin care: Bletilla striata contains rich starch, glucose, volatile oil and mucus. Applying it externally can eliminate the marks left by acne on the face and moisturize and whiten the skin. In addition, the β-glucan in Bletilla striata has anti-aging and anti-wrinkle effects, can stimulate macrophage activation, promote the migration of fibroblasts and keratinocytes, thereby accelerating wound healing and anti-aging processes.

[0063] Musk for external use has the effect of promoting blood circulation and dredge menstruation: Musk has the effect of promoting blood circulation and dredge menstruation, and can be used to treat symptoms such as blood stasis, amenorrhea, and sudden pain in the heart and abdomen. Reduce swelling and relieve pain: Musk can treat sores, swelling, and injuries, and has the effect of reducing swelling and relieving pain. Anti-inflammatory: Musk can promote blood circulation throughout the body, accelerate the absorption and disappearance of inflammation. Musk for external use can also promote wound healing. It can promote the proliferation of epithelial cells, accelerate the wound repair process, and reduce the formation of scars. This effect makes musk have potential application value in the field of wound repair.

[0064] Pig bile powder is obtained by concentrating, filtering, drying and crushing pig bile. It is rich in nutrients such as protein, vitamins, trace elements, etc., which are beneficial to wound repair. It also has antibacterial and anti-inflammatory effects, can inhibit the activity of various viruses, achieve antibacterial and anti-inflammatory effects, and can be used to treat skin diseases such as psoriasis.

[0065] On the other hand, an embodiment of the present invention provides a method for preparing an antibacterial powder, comprising:

[0066] S1, peeling the musk, sterilizing and disinfecting it, crushing and sieving it to obtain musk powder;

[0067] S2, crush the remaining raw materials separately, sieve them, add musk powder, and mix them evenly.

[0068] In steps S1 and S2, the mesh size of the sieving is 200 meshes.

[0069] The features and performance of the present invention are further described in detail below in conjunction with the embodiments.

[0070] Example 1

[0071] According to the following ratio, prepare the raw materials of this embodiment:

[0072] 20 parts of Radix Sanguisorbae, 18 parts of Rhizoma Coptidis, 20 parts of Cortex Phellodendri, 20 parts of Radix Rhei, 15 parts of Rhizoma Bletillae, 18 parts of Musk, 15 parts of Pig Gallbladder Powder.

[0073] S1, peeling the musk, sterilizing and disinfecting it, crushing it through a 200-mesh sieve, further crushing the sieved components, and repeatedly sieving them to obtain musk powder;

[0074] S2, respectively crushing raw Sanguisorba officinalis, Coptis chinensis, Phellodendron amurense, raw Rhubarb and Bletilla striata, passing through a 200-mesh sieve, adding musk powder and pig gall powder, and mixing evenly to obtain the antibacterial powder of this embodiment.

[0075] Example 2

[0076] According to the following ratio, prepare the raw materials of this embodiment:

[0077] 15 parts of Radix Sanguisorbae, 25 parts of Rhizoma Coptidis, 15 parts of Cortex Phellodendri, 10 parts of Radix Rhei, 20 parts of Rhizoma Bletillae, 25 parts of Musk, 25 parts of Pig Gallbladder Powder.

[0078] S1, peeling the musk, sterilizing and disinfecting it, crushing it through a 200-mesh sieve, further crushing the sieved components, and repeatedly sieving them to obtain musk powder;

[0079] S2, respectively crushing raw Sanguisorba officinalis, Coptis chinensis, Phellodendron amurense, raw Rhubarb and Bletilla striata, passing through a 200-mesh sieve, adding musk powder and pig gall powder, and mixing evenly to obtain the antibacterial powder of this embodiment.

[0080] Example 3

[0081] According to the following ratio, prepare the raw materials of this embodiment:

[0082] 25 parts of Radix Sanguisorbae, 20 parts of Rhizoma Coptidis, 15 parts of Cortex Phellodendri, 25 parts of Radix Rhei, 10 parts of Rhizoma Bletillae, 15 parts of Musk, 10 parts of Pig Gallbladder Powder.

[0083] S1, peeling the musk, sterilizing and disinfecting it, crushing it through a 200-mesh sieve, further crushing the sieved components, and repeatedly sieving them to obtain musk powder;

[0084] S2, respectively crushing raw Sanguisorba officinalis, Coptis chinensis, Phellodendron amurense, raw Rhubarb and Bletilla striata, passing through a 200-mesh sieve, adding musk powder and pig gall powder, and mixing evenly to obtain the antibacterial powder of this embodiment.

[0085] Example 4

[0086] According to the following ratio, prepare the raw materials of this embodiment:

[0087] 15 parts of Radix Sanguisorbae, 15 parts of Rhizoma Coptidis, 30 parts of Cortex Phellodendri, 10 parts of Radix Rhei, 25 parts of Rhizoma Bletillae, 15 parts of Musk, 25 parts of Pig Gallbladder Powder.

[0088] S1, peeling the musk, sterilizing and disinfecting it, crushing it through a 200-mesh sieve, further crushing the sieved components, and repeatedly sieving them to obtain musk powder;

[0089] S2, respectively crushing raw Sanguisorba officinalis, Coptis chinensis, Phellodendron amurense, raw Rhubarb and Bletilla striata, passing through a 200-mesh sieve, adding musk powder and pig gall powder, and mixing evenly to obtain the antibacterial powder of this embodiment.

[0090] Experimental example

[0091] Animal Experimentation:

[0092] A number of mice with good growth status and uniform size were selected and divided into a normal group, a blank control group and experimental groups 1-4, with 10 mice in each group. Under anesthesia, the side of the head of the mice in the blank control group and experimental groups 1-4 was punctured to obtain an area of ​​about 1cm 2 The wound surface of the mouse head of the experimental group 1-4 was evenly sprinkled with the antibacterial powder prepared in Example 1-4, and the hemostatic effect was observed. After the bleeding stopped, the sterile gauze was fixed, and the wound healing was observed after 24 hours; the gauze and antibacterial powder were then replaced once a day until the wound healed. The blank control group did not apply the antibacterial powder, and the rest were treated in the same way as the experimental group. The normal group did not do wound treatment, and the mice in each group were fed and watered normally. The observation results are shown in Table 1.

[0093] Table 1 Wound healing of mice in each group

[0094]

[0095] It can be concluded from Table 1 that the antibacterial powder provided in the embodiment of the present invention can quickly stop bleeding within 30 seconds, the wound surface heals and forms a scab after 24 hours, and it is not easy to leave scars after the wound is completely healed and normal skin grows.

[0096] Clinical trials:

[0097] The results of the experiment on 66 patients with various injuries in the Traumatology Department of Anhui Wanbei Coal and Electricity General Hospital using the antibacterial powder of Example 1 showed that 100% of them were clinically cured without any toxic side effects. Fig.19 shown.

[0098] Typical cases:

[0099] Case 1: A diabetic foot patient, female, 86 years old. Suzhou Yongqiao High-tech Zone. She has had diabetes for many years, and her foot has been damaged for more than a year. She has severe pain and cannot sleep all night. She has been treated in many hospitals but the results are not good. She is given dressing treatment at home (the antibacterial powder of Example 1). A large area of ​​skin necrosis and tendon exposure on the back of the right foot, accompanied by necrosis of three toes, a lot of foul-smelling exudate, and obvious swelling on the sole of the foot. After 2.5 months of treatment with the antibacterial powder of Example 1, the wound healed. The wound before, during and after treatment is as shown in the attached figure. Figure 1-3 shown.

[0100] Case 2: Patient with diabetic foot, Li XX, male, 76 years old, from Liqiao Village, Fuli Town, Yongqiao District. He had diabetes for more than 20 years. He had a bad foot for half a year and was given toe amputation and oral hypoglycemic drugs in a higher-level hospital, but the effect was not good. His blood sugar level was always around 15-20 after the operation. The incision did not heal for more than 8 months after the operation. He was treated with the antibacterial powder of Example 1 and was cured after 3 months of treatment without skin grafting and without scars. The wound surface before, during and after treatment is shown in the attached figure. Figure 4-6 shown.

[0101] Case 3: Patient with diabetic foot, Wang XX, male, 76 years old. Wangzhuang Community, South Outer Ring Road, Suzhou City, had diabetic foot damage for more than half a year. He was given dressing change and hypoglycemic treatment by many hospitals, but the effect was not good. During the course of the disease, the pain in the affected limb was unbearable, and he often took painkillers orally. His blood sugar was always around 15. After treatment with the antibacterial powder of Example 1, he was cured after two months. The wound surface before, during and after treatment is shown in the attached figure. Figure 7-9 shown.

[0102] Case 4: Diabetic foot patient, Zhou XX, male, 76 years old. He lived in Minci Village, Caocun Town, Suzhou City. He had diabetes for many years and diabetic foot damage for more than half a year. He was given dressing change and hypoglycemic treatment in many large hospitals in Xuzhou, but the effect was not good. His blood sugar was always around 18. He came to our clinic for treatment with Chinese medicine powder and was treated with the antibacterial powder of Example 1. He was cured after two and a half months of treatment with the antibacterial powder.

[0103] Case 5: Patient with diabetic foot, Zhang XX, male, 60 years old. Zhaoji, Jiagou Town, Suzhou City, has had diabetes for many years, is blind, and has had diabetic foot damage for more than half a year. He has been given dressing and hypoglycemic treatment by many large hospitals such as Suzhou and Xuzhou Renci, but the effect is not good. He often injects insulin during the course of the disease, and his blood sugar has always been around 10. Physical examination: The fistula in the anterior lower part of the left medial malleolus is connected to the sole of the foot, and pus exudates a lot with a foul odor. Use gauze strips and powder to penetrate and drain, and strengthen dressing. This method of dressing was used to change the dressing for one month and he was cured.

[0104] Case 6: Diabetic foot patient Pang XX, female, 68 years old. From Panggezhuang, Daxing District, Beijing, she suffered from long-term diabetes for about a year and a half in 2017, and was admitted to the PLA 301 Hospital in July 2018. The hospital recommended surgical resection, but the patient refused. She started using antibacterial powder in August 2018 and was cured after 22 days. Fig.10 shown.

[0105] Case 7: Patient with venous ulcer of lower limbs, Yin XX, male, 75 years old, from Xiaqiao Village, Shicun Town, Suzhou City. He had been suffering from leg ulcer caused by varicose veins for more than two years. He did not see any improvement after treatment at a higher-level hospital. He was cured after three months of treatment with the antibacterial powder of Example 1. The treatment process is as follows: Fig.11 shown.

[0106] Case 8: A 76-year-old woman with lower extremity venous ulcers from Zhangzhuang, Fuli Town, Suzhou City, had diabetic nephropathy and chronic bronchitis and had long-term use of hormones. She had skin avulsion and a large area of ​​skin defect that could not be grafted. She was cured after one and a half months of treatment with antibacterial powder. The natural raw skin had no scars. The treatment process was as follows: Fig.12 shown.

[0107] Case 9: Patient infected with Morganella morganii, Yan XX, male, 65 years old, from Yugou Town, Suzhou, Anhui, developed flaky ulcers and muscle bulging on both lower limbs in April 2019. After symptomatic treatment at Nanjing Dermatology Hospital of Chinese Academy of Sciences, Peking Union Medical College Hospital and Xuzhou People's Hospital, the effect was not significant. He was cured after 45 days of treatment with the antibacterial powder of Example 1.

[0108] Case 10: Patient with cervical lymph node, Zhang XX, male, 43 years old, from Huigu Village, Huigu Town, Suzhou City, was treated for cervical lymph node tuberculosis in a higher-level hospital for two months without healing after changing the dressing. The pus was deep into the sternocleidomastoid muscle. After half a month of treatment with antibacterial powder, the disease was cured and there was no scar on the skin. Fig.13 shown.

[0109] Case 11: Traumatic injury patient, Zhang XX, male, 58 years old, from Minxian Village, Caocun Town, Suzhou City. The skin defect on the dorsum of the foot due to trauma did not heal for 8 months. It was cured after 20 days of treatment with antibacterial powder. The treatment process is as follows Fig.14 shown.

[0110] Case 12: Patient with bedsore, elderly, female, 83 years old. Xieji Township, Yongqiao District, Suzhou. She was paralyzed for many years due to cerebrovascular disease, and had bedsores on her buttocks for more than a year. She had been treated in many hospitals but the results were not good. She is now receiving dressing treatment at home. A large area of ​​ulceration on the buttocks, deep into the fascia, with a lot of foul-smelling exudate. After one month of treatment with antibacterial powder, she was cured and there was no scar on the skin. The treatment process is as follows: Fig.15 shown.

[0111] Case 13: Bed sore patient, elderly male, 69 years old, developed bedsore due to long-term bed rest. He received dressing and symptomatic treatment in several hospitals with good results. He then came to our center for treatment with antibacterial powder and recovered after two months. Fig.16 shown.

[0112] Case 14: Bed sore patient, elderly male, 72 years old, sequelae of cerebral hemorrhage, long-term bed rest formed bedsore for more than half a year. He was given dressing and symptomatic treatment in many hospitals, but the effect was not good. He came to our center to use antibacterial powder Chinese medicine treatment and recovered after two and a half months. His treatment process is as follows Fig.17 shown.

[0113] Case 15: Bed sore patient, the patient is an elderly male, 76 years old, paralyzed in bed for a long time, the bottom of the heel was ulcerated for more than two years, and it has not healed after treatment in many hospitals. He came to our center to use antibacterial powder Chinese medicine treatment, and he was cured after two months. The treatment process is as follows Fig.18 shown.

[0114] In summary, the antibacterial powder provided by the embodiment of the present invention uses raw sanguisorba officinalis, coptis root, phellodendron, raw rhubarb, bletilla striata, musk and pig gall powder as raw materials, has rapid hemostasis, and can quickly stop bleeding and relieve pain in fresh wounds within 5-15 seconds; can remove dead tissue and regenerate new muscles, promote in situ cell growth, has the effects of astringency, pus discharge, raw skin and meat growth, has good antibacterial effect on wound surface, and has strong antibacterial ability and wide application range. It is easy to use, and it directly acts on the wound surface, and has a direct repair effect on the skin of diabetic distal limbs that are no longer circulating, severe burn wounds, pressure sores (bedsores) wounds and various traumatic infection wounds, can awaken dormant cells, repair damaged cells, promote cell in situ regeneration and tissue reduction, improve microcirculation, and accelerate wound healing.

[0115] The embodiments described above are part of the embodiments of the present invention, rather than all of the embodiments. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

Claims

1. An antibacterial powder, characterized in that: The following raw materials are included by weight: 15-30 parts of raw Sanguisorba officinalis, 15-25 parts of Coptidis rhizome, 15-30 parts of Phellodendron chinense, 10-25 parts of raw rhubarb, 10-20 parts of Bletilla striata, 15-25 parts of Musk, and 10-25 parts of pig gall powder.

2. The antibacterial powder according to claim 1, characterized in that The invention comprises the following raw materials by weight: 20 parts of raw Sanguisorba officinalis, 18 parts of Coptis chinensis, 20 parts of Phellodendron amurense, 20 parts of raw rhubarb, 15 parts of Bletilla striata, 18 parts of Musk and 15 parts of pig gall powder.

3. The antibacterial powder according to claim 1, characterized in that The invention comprises the following raw materials by weight: 15 parts of raw Sanguisorba officinalis, 25 parts of Coptis chinensis, 15 parts of Phellodendron amurense, 10 parts of raw rhubarb, 20 parts of Bletilla striata, 25 parts of Musk and 25 parts of pig gall powder.

4. A method for preparing the antibacterial powder according to any one of claims 1 to 3, characterized in that: The following steps are involved: S1, peeling the musk, sterilizing and disinfecting it, crushing and sieving it to obtain musk powder; S2, crush the remaining raw materials separately, sieve them, add musk powder, and mix them evenly.

5. The method for preparing the antibacterial powder according to claim 4, characterized in that: In steps S1 and S2, the mesh size of the sieving is 200 meshes.

Images