Irreversible electroporation ablation assembly with movable electrode assembly

Abstract

The invention discloses an irreversible electroporation ablation assembly with a movable electrode assembly, and relates to the technical field of medical instruments, the irreversible electroporation ablation assembly comprises an ablation assembly main body, the ablation assembly main body comprises an ablation gun, the upper surface of the ablation gun is fixedly connected with a handle, the bottom surface of the ablation gun is fixedly connected with an extension cylinder, and the extension cylinder is fixedly connected with a movable electrode assembly. The irreversible electroporation ablation assembly with the movable electrode assembly comprises an ablation gun, an extension cylinder is arranged in the ablation gun, an ablation needle fixedly communicates with the bottom surface of the extension cylinder, a plurality of ablation electrodes are jointly slidably connected to the interior of the ablation needle and the interior of the extension cylinder, and an installation clamping mechanism is arranged below the ablation gun. The irreversible electroporation ablation assembly is installed on the body surface of a patient, the problem that the position is inaccurate due to the fact that a surgeon inserts the assembly into the target position of the patient in a bare-handed mode is solved, the assembly is installed in the connecting and installing unit, the position is positioned, and the using precision of the irreversible electroporation ablation assembly is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to an irreversible electroporation ablation component with a movable electrode component. Background Art

[0002] Electroporation is a novel ablation technique that has the potential to overcome the major drawbacks of other ablation methods. It uses electrical pulses propagated between two or more electrodes to form "nanopores" in cell membranes. If the applied current reaches a certain threshold, these nanopores become permanent, resulting in cell death. Irreversible electroporation has been shown to effectively and safely destroy tumor cells while preserving tissue architecture and minimizing damage to blood vessels and important urinary system structures. One method of implementing irreversible electroporation is to insert an electrode needle into the target location for treatment.

[0003] The existing irreversible electroporation ablation component is directly inserted into the patient's target position by the surgeon's bare hands to kill tumor cells using electric pulses transmitted between two or more electrodes. However, the accuracy of manually inserting the component into the patient's target position is low, which makes it easy for the component to not accurately destroy and kill tumor cells. In addition, the component inserted into the patient's target position is prone to shaking, which may cause the position between the discharge end electrodes of the component to change, further affecting the accuracy of the use of the irreversible electroporation ablation component. To this end, we propose an irreversible electroporation ablation component with a movable electrode component.

[0004] Combining the above problems, we will find that it is difficult to avoid the above problems at the same time when using the existing irreversible electroporation ablation components on the market, and even if they can be solved, they need to be solved with the cooperation of external tools, which makes it impossible to achieve the desired effect. Therefore, we propose an irreversible electroporation ablation component with a movable electrode assembly. Summary of the invention

[0005] The object of the present invention is to provide an irreversible electroporation ablation assembly with a movable electrode assembly to solve the problems raised in the above background technology.

[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an irreversible electroporation ablation assembly with a movable electrode assembly, comprising an ablation assembly body, the ablation assembly body comprising an ablation gun, the upper surface of the ablation gun is fixedly connected with a handle, the bottom surface of the ablation gun is fixedly connected with an extension tube, the bottom surface of the extension tube is fixedly connected with an ablation needle, the interior of the ablation needle and the interior of the extension tube are slidably connected with a plurality of ablation electrodes, and a mounting clamping mechanism is arranged below the ablation gun; The mounting and clamping mechanism comprises a connecting and mounting unit, the connecting and mounting unit is located below the ablation gun, and the connecting and mounting unit is used to stably mount the irreversible electroporation ablation assembly on the patient's body surface; The installation and clamping mechanism comprises a clamping and stabilizing unit, the clamping and stabilizing unit is located outside the extension tube, the connection and installation unit is used in conjunction with the clamping and stabilizing unit, and the clamping and stabilizing unit is used to stably clamp the irreversible electroporation ablation component; A precise measuring mechanism is arranged on the back of the clamping and stabilizing unit. The precise measuring mechanism is used in conjunction with the installation clamping mechanism and is used to precisely measure the extension size of the irreversible electroporation ablation component.

[0007] Preferably, the connecting and mounting unit includes a mounting frame, which is arranged on the outside of the ablation needle, and the bottom surface of the mounting frame is fixedly connected to four supporting tubes, the interior of each supporting tube is slidably connected to an extension tube, the outer surface of each supporting tube and the outer surface of each extension tube are threadedly connected to a tightening nut, the bottom surface of each extension tube is movably hinged with a vacuum suction cup, the outer surface of each extension tube is fixedly connected to a connecting tube, the bottom end of each connecting tube passes through the vacuum suction cup and extends to the inside of the vacuum suction cup, the upper surface of the mounting frame is fixedly connected to an exhaust pipe, the top end of each extension tube is fixedly connected to the outer surface of the exhaust pipe through a telescopic hose, the upper surface of the mounting frame is fixedly connected to the vacuum pipe, the ends of the exhaust pipes close to each other are fixedly connected to the outer surface of the vacuum pipe, and the outer surface of the mounting frame A connecting frame is fixedly connected, and four limiting cylinders are fixedly connected to the upper surface of the connecting frame. A rotating motor is arranged above the connecting frame, and the bottom surface of the rotating motor contacts the top of the vacuum tube. A sliding frame is fixedly connected to the outer surface of the rotating motor, and four limiting columns are fixedly connected to the bottom surface of the sliding frame. The four limiting columns are respectively slidably connected to the inside of the four limiting cylinders. A rotating shaft is fixedly connected to the output end of the rotating motor, and a rotating disk is fixedly connected to the outer surface of the rotating shaft. The rotating disk is rotatably connected to the inside of the vacuum tube, and a guide sliding block is fixedly connected to the outer surface of the rotating disk. A guide sliding groove is provided on the inner wall of the vacuum tube, and the guide sliding block is slidably connected to the inner cavity of the guide sliding groove. A silicone piston is fixedly connected to the bottom end of the rotating shaft, and the silicone piston is slidably connected to the inside of the vacuum tube.

[0008] Preferably, the outer surface of each vacuum suction cup is adhered with medical tapes arranged in a circumferential manner at equal distances, and the adhesive surface of each medical tape is adhered to the patient's body surface.

[0009] Preferably, the clamping and stabilizing unit includes a stabilizing cylinder, the extension cylinder is slidably connected to the interior of the stabilizing cylinder, the outer sleeve of the stabilizing cylinder is provided with an upper limit frame, the bottom surface of the upper limit frame is fixedly connected with four limit connecting rods, the inner wall of the mounting frame is fixedly connected with four connecting reinforcement plates, the bottom ends of the four limit connecting rods are respectively fixedly connected to the upper surfaces of the four connecting reinforcement plates, the outer surface of the stabilizing cylinder is respectively fixedly connected with an upper limit ring and a conical ring, the bottom surface of the upper limit ring is fixedly connected to the upper surface of the conical ring, the back side of the sliding frame is fixedly connected with a movable plate, the back side of the movable plate is fixedly connected with a clamping ring, the inner wall of the clamping ring is fixedly connected with clamping buckles arranged at equal distances, and the side surfaces of several clamping buckles close to each other are in contact with the outer surface of the conical ring.

[0010] Preferably, a lower limit frame is fixedly connected to the side surfaces of the four connecting reinforcement plates that are close to each other, and the outer surface of the stabilizing cylinder is in contact with the inner wall of the lower limit frame.

[0011] Preferably, a lower limiting ring is arranged above the lower limiting frame, and the inner wall of the lower limiting ring is fixedly connected to the outer surface of the stabilizing cylinder.

[0012] Preferably, the bottom surface of the stabilizing cylinder is fixedly connected to a sliding positioning cylinder, and the ablation needle is slidably connected to the interior of the sliding positioning cylinder.

[0013] Preferably, both side surfaces of the sliding frame are fixedly connected with a first connecting rod, and the ends of the two first connecting rods that are away from each other are fixedly connected with a positioning slip ring, the inner walls of the two positioning slip rings are respectively in contact with the outer surfaces of two of the limiting connecting rods, the outer surface of each positioning slip ring is fixedly connected with a second connecting rod, and the ends of the two second connecting rods that are close to each other are fixedly connected to the outer surface of the clamping ring.

[0014] Preferably, the precise measuring mechanism comprises a measuring fixing ring, the inner wall of which is fixedly connected to the outer surface of the ablation gun, the outer surface of the measuring fixing ring is fixedly connected to a first measuring scale, the interior of the first measuring scale is slidably connected to a first extension scale, the outer surface of the lower limit ring is fixedly connected to a second measuring scale, the interior of the second measuring scale is slidably connected to a second extension scale, and the back sides of the first measuring scale, the first extension scale, the second measuring scale and the second extension scale are all fixedly connected to precise scales.

[0015] Preferably, the bottom surfaces of the first extension ruler and the second extension ruler are both fixedly connected to lower bottom plates, and the bottom surface of one of the lower bottom plates is in contact with the upper surface of the second measuring ruler.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention can stably install the irreversible electroporation ablation component on the patient's body surface by providing a connecting and installing unit, thereby reducing the need for the surgeon to directly insert the irreversible electroporation ablation component into the patient's target position by hand, which may cause the problem of inaccurate insertion position. It is only necessary to stably connect the connecting and installing unit to the required position on the patient's body surface, install the irreversible electroporation ablation component inside the connecting and installing unit and locate the position, so that the irreversible electroporation ablation component can be used accurately, thereby improving the use accuracy of the irreversible electroporation ablation component.

[0017] 2. The present invention provides a clamping and stabilizing unit, which can stably clamp the stabilizing cylinder on which the irreversible electroporation ablation component is installed when the connecting and installing unit is installed at the required position on the patient's body surface, thereby clamping and positioning the installation position of the irreversible electroporation ablation component, thereby avoiding the problem of changes in the position of the discharge end electrodes of the component due to shaking of the component inserted into the target position of the patient, thereby further improving the use accuracy of the irreversible electroporation ablation component.

[0018] 3. The present invention provides a precise measuring mechanism, which can measure the distance between the irreversible electroporation ablation component and the patient's body surface by cooperating with the connecting installation unit and the clamping and stabilizing unit, through a first measuring ruler and a first extension ruler disposed outside the ablation gun, and by utilizing a second measuring ruler and a second extension ruler disposed outside the stabilizing cylinder, thereby being able to conveniently and accurately determine the extension size of the irreversible electroporation ablation component, and further being able to accurately use the irreversible electroporation ablation component. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is a bottom view structural schematic diagram of the vacuum suction cup of the present invention; Figure 3 It is a structural schematic diagram of the air extraction pipe of the present invention; Figure 4 It is a schematic cross-sectional structural diagram of the vacuum tube of the present invention; Figure 5 It is a structural schematic diagram of the rotating motor of the present invention; Figure 6 It is a schematic diagram of the structure of the stabilizing cylinder of the present invention; Figure 7 It is a schematic diagram of the rear view and bottom view of the second measuring ruler of the present invention; Figure 8 It is a structural schematic diagram of the ablation gun of the present invention; Fig. 9 It is a schematic diagram of the rear view structure of the first measuring ruler of the present invention.

[0020] In the figure: 1, ablation assembly body; 11, ablation gun; 12, grip; 13, extension tube; 14, ablation needle; 15, ablation electrode; 2. Install the clamping mechanism; 21. Connect the installation unit; 2101. Install the frame; 2102. Support cylinder; 2103. Extension tube; 2104. Tighten the nut; 2105. Vacuum suction cup; 2106. Connecting tube; 2107. Medical tape; 2108. Vacuum pipe; 2109. Connecting frame; 2110. Limiting cylinder; 2111. Vacuuming tube; 2112. Limiting column; 2113. Sliding frame; 2114. Rotating motor; 2115. Rotating shaft; 2116, rotating disk; 2117, guide sliding block; 2118, silicone piston; 2119, guide sliding groove; 22, clamping and stabilizing unit; 2201, connecting reinforcement plate; 2202, limit connecting rod; 2203, upper limit frame; 2204, stabilizing cylinder; 2205, upper limit ring; 2206, lower limit ring; 2207, sliding positioning cylinder; 2208, conical ring; 2209, moving plate; 2210, clamping ring; 2211, clamping buckle; 2212, first connecting rod; 2213, positioning slip ring; 2214, second connecting rod; 2215, lower limit frame; 3. Precision measuring mechanism; 301. Measuring fixing ring; 302. First measuring ruler; 303. First extension ruler; 304. Second measuring ruler; 305. Second extension ruler; 306. Lower base plate; 307. Precision scale ruler. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Embodiment 1

[0022] See also Figure 1-9The present invention provides a technical solution: an irreversible electroporation ablation component with a movable electrode assembly, comprising an ablation component body 1, the ablation component body 1 comprising an ablation gun 11, the upper surface of the ablation gun 11 is fixedly connected with a handle 12, the bottom surface of the ablation gun 11 is fixedly connected with an extension tube 13, the bottom surface of the extension tube 13 is fixedly connected with an ablation needle 14, the interior of the ablation needle 14 and the interior of the extension tube 13 are slidably connected with a plurality of ablation electrodes 15, and a mounting clamping mechanism 2 is arranged below the ablation gun 11, the ablation gun 11, the handle 12, the extension tube 13, the ablation needle 14 and the ablation electrode 15 form the main body of the irreversible electroporation ablation component, and the plurality of ablation electrodes 15 are slidably inside the ablation needle 14 and the extension tube 13, so that the irreversible electroporation ablation component can have a movable electrode assembly, thereby facilitating the use of the irreversible electroporation ablation component to destroy and kill tumor cells in a patient's body; The mounting clamping mechanism 2 comprises a connecting and mounting unit 21 , which is located below the ablation gun 11 . The connecting and mounting unit 21 is used to stably mount the irreversible electroporation ablation assembly on the patient's body surface.

[0023] As a further limitation of the mounting clamping mechanism 2 of the present invention, the connecting mounting unit 21 includes a mounting frame 2101, which is arranged outside the ablation needle 14, and the bottom surface of the mounting frame 2101 is fixedly connected with four support cylinders 2102, and the interior of each support cylinder 2102 is slidably connected with an extension tube 2103, and the outer surface of each support cylinder 2102 and the outer surface of each extension tube 2103 are threadedly connected with a tightening nut 2104, and the bottom surface of each extension tube 2103 is movably hinged with a vacuum suction cup 2105. The outer surface of each vacuum suction cup 2105 is adhered with medical tape 2107 arranged in an equidistant circle, and the adhesive surface of each medical tape 2107 is adhered to the patient's body surface. The medical tape 2107 arranged on the outer surface of the vacuum suction cup 2105 can be adhered to the patient's body surface, so that the irreversible electroporation ablation component can be pre-installed to the required position on the patient's body surface, and then the vacuum suction cup 2105 is used to absorb the patient's body surface to ensure that the irreversible electroporation ablation component is firmly installed at the required position on the patient's body surface.

[0024] The outer surface of each extension tube 2103 is fixedly connected with a connecting tube 2106, and the bottom end of each connecting tube 2106 passes through the vacuum suction cup 2105 and extends to the inside of the vacuum suction cup 2105. The upper surface of the mounting frame 2101 is fixedly connected with an exhaust pipe 2108, and the top of each extension tube 2103 is fixedly connected with the outer surface of the exhaust pipe 2108 through a telescopic hose. The upper surface of the mounting frame 2101 is fixedly connected with a vacuum tube 2111, and the ends of the exhaust pipes 2108 that are close to each other are fixedly connected with the outer surface of the vacuum tube 2111. The outer surface of the mounting frame 2101 is fixedly connected with a connecting frame 2109, and the upper surface of the connecting frame 2109 is fixedly connected with four limiting cylinders 2110. A rotating motor 2114 is provided, and the bottom surface of the rotating motor 2114 contacts the top of the vacuum tube 2111, and the outer surface of the rotating motor 2114 is fixedly connected to a sliding frame 2113, and the bottom surface of the sliding frame 2113 is fixedly connected to four limiting columns 2112, and the four limiting columns 2112 are respectively slidably connected to the inside of the four limiting cylinders 2110. By utilizing the power provided by the rotating motor 2114, the structure can be utilized to make the rotating motor 2114 move up and down, so that the four limiting columns 2112 slide inside the four limiting cylinders 2110, and the cooperation between the four limiting columns 2112 and the four limiting cylinders 2110 is utilized to limit the rotation of the rotating motor 2114, thereby facilitating the driving of the rotating motor 2114 to move up and down.

[0025] The output end of the rotating motor 2114 is fixedly connected to a rotating shaft 2115, the outer surface of the rotating shaft 2115 is fixedly connected to a rotating disk 2116, the rotating disk 2116 is rotatably connected to the inside of the vacuum tube 2111, the outer surface of the rotating disk 2116 is fixedly connected to a guide sliding block 2117, the inner wall of the vacuum tube 2111 is provided with a guide sliding groove 2119, the guide sliding block 2117 is slidably connected to the inner cavity of the guide sliding groove 2119, the bottom end of the rotating shaft 2115 is fixedly connected to a silicone piston 2118, the silicone piston 2118 is slidably connected to the inside of the vacuum tube 2111, and the vacuum tube 2111 is rotatably connected to the inside of the vacuum tube 2111. By driving the rotating disk 2116 to rotate inside the vacuum tube 2111 through the rotating motor 2114, the guide sliding block 2117 can slide in the inner cavity of the guide sliding groove 2119, which can drive the rotating disk 2116 to move up and down inside the vacuum tube 2111, and the silicone piston 2118 can move up and down inside the vacuum tube 2111 to extract the air between the vacuum suction cup 2105 and the patient's body surface through the vacuum tube 2111, so that the vacuum suction cup 2105 can be adsorbed on the patient's body surface, and the irreversible electroporation ablation component can be stably installed to the required position.

[0026] The specific implementation of this embodiment is as follows: when the doctor needs to use the irreversible electroporation ablation component with a movable electrode component to install it at the required position on the patient's body surface to accurately destroy and kill the tumor cells in the patient's body, the four vacuum suction cups 2105 set at the bottom of the component are first manually brought into contact with the patient's body surface, and the position below the ablation needle 14 fixedly connected under the extension tube 13 is made to correspond to the position where the patient needs to insert the needle, and the multiple medical tapes 2107 pasted on the outer surface of the vacuum suction cup 2105 are pasted to the required position on the patient's body surface, so that the irreversible electroporation ablation component can be pre-installed on the patient The extension tube 2103 sliding in the support tube 2102 is manually moved to adjust the distance between the mounting frame 2101 and the patient's body surface, so that the relative position between the support tube 2102 and the extension tube 2103 is fixed by manually twisting the tightening nut 2104. Since the extension tube 2103 and the vacuum suction cup 2105 are spherically hinged, the vacuum suction cup 2105 can fit the complex body surface of the patient. Then, the power supply of the rotating motor 2114 is controlled by the PLC controller, and the rotating motor 2114 can be used to drive the rotating shaft 2115 to rotate. The rotating disk 2116 and the silicone piston 2118 rotate in the vacuum tube 2111, and the guide sliding block 2117 fixed outside the rotating disk 2116 cooperates with the guide sliding groove 2119 in the vacuum tube 2111, and the sliding frame 2113 fixed outside the rotating motor 2114 is slid by the limiting column 2112 fixed under the sliding frame 2113 in the limiting cylinder 2110 fixed on the connecting frame 2109, so that the rotation of the rotating motor 2114 can be limited, so that the rotating motor 2114 can only drive the rotating shaft 2115, the rotating disk 2116 and the silicone piston 2118 to move in the vacuum tube 2111. 1, and due to the interference fit between the silicone piston 2118 and the vacuum tube 2111, the movement of the silicone piston 2118 can transport the air between the vacuum suction cup 2105 and the patient's body surface to the vacuum tube 2111 through the extension tube 2103, the connecting tube 2106 and the exhaust tube 2108, until the air between the vacuum suction cup 2105 and the patient's body surface is evacuated, so that the vacuum suction cup 2105 can be firmly adsorbed on the patient's body surface, so that the irreversible electroporation ablation component can be stably installed on the patient's skin surface, and the irreversible electroporation ablation component can be used to treat the patient accurately and stably. Embodiment 2

[0027] See also Figure 1-9 The present invention provides a technical solution: an irreversible electroporation ablation component with a movable electrode component. The present invention makes corresponding improvements to the technical problems mentioned in the background technology.

[0028] As a further limitation of the installation and clamping mechanism 2 of the present invention, the installation and clamping mechanism 2 includes a clamping and stabilizing unit 22, which is located outside the extension tube 13, and the installation unit 21 is connected and used in conjunction with the clamping and stabilizing unit 22, and the clamping and stabilizing unit 22 is used to stably clamp the irreversible electroporation ablation component.

[0029] The clamping and stabilizing unit 22 includes a stabilizing cylinder 2204, the extension cylinder 13 is slidably connected to the inside of the stabilizing cylinder 2204, the bottom surface of the stabilizing cylinder 2204 is fixedly connected to a sliding positioning cylinder 2207, and the ablation needle 14 is slidably connected to the inside of the sliding positioning cylinder 2207. The extension cylinder 13 can slide inside it through the stabilizing cylinder 2204, so that the ablation needle 14 fixed on the bottom surface of the extension cylinder 13 can slide inside it by utilizing the sliding positioning cylinder 2207 fixedly connected to the bottom surface of the stabilizing cylinder 2204, thereby facilitating the use of the ablation needle 14 to be inserted into the patient's body to destroy and kill tumor cells.

[0030] An upper limit frame 2203 is provided on the outside of the stabilizing cylinder 2204, and four limit connecting rods 2202 are fixedly connected to the bottom surface of the upper limit frame 2203. Four connecting reinforcement plates 2201 are fixedly connected to the inner wall of the mounting frame 2101. The bottom ends of the four limit connecting rods 2202 are respectively fixedly connected to the upper surfaces of the four connecting reinforcement plates 2201. The side surfaces of the four connecting reinforcement plates 2201 that are close to each other are commonly fixedly connected to a lower limit frame 2215. The outer surface of the stabilizing cylinder 2204 is in contact with the inner wall of the lower limit frame 2215. The lower limit frame 2215 can be used to limit the movable stabilizing cylinder 2204, thereby improving the stability of the up and down movement of the stabilizing cylinder 2204.

[0031] A lower limit ring 2206 is arranged above the lower limit frame 2215, and the inner wall of the lower limit ring 2206 is fixedly connected to the outer surface of the stabilizing cylinder 2204. The lower limit ring 2206 is fixed by using the outer surface of the stabilizing cylinder 2204, and the movement of the stabilizing cylinder 2204 can be stabilized and limited through the contact between the lower limit ring 2206 and the lower limit frame 2215.

[0032] The outer surface of the stabilizing cylinder 2204 is respectively fixedly connected with an upper limit ring 2205 and a conical ring 2208, the bottom surface of the upper limit ring 2205 is fixedly connected with the upper surface of the conical ring 2208, the back of the sliding frame 2113 is fixedly connected with a moving plate 2209, the back of the moving plate 2209 is fixedly connected with a clamping ring 2210, the inner wall of the clamping ring 2210 is fixedly connected with clamping buckles 2211 arranged at equal distances, and the side surfaces of several clamping buckles 2211 that are close to each other are in contact with the outer surface of the conical ring 2208, and the two side surfaces of the sliding frame 2113 are fixedly connected with first connecting rods 2212, and the two first connecting rods 2212 are far away from each other. One end of each of the two positioning slip rings 2213 is fixedly connected with a positioning slip ring 2213, and the inner walls of the two positioning slip rings 2213 are respectively in contact with the outer surfaces of two of the limit connecting rods 2202, and the outer surface of each positioning slip ring 2213 is fixedly connected with a second connecting rod 2214, and the ends of the two second connecting rods 2214 close to each other are fixedly connected to the outer surface of the clamping ring 2210, and the positioning slip ring 2213 is fixed between the two first connecting rods 2212 and the two second connecting rods 2214, and the positioning slip ring 2213 can be used to slide on the outer surface of the limit connecting rod 2202, so that the sliding frame 2113 can stably drive the clamping ring 2210 to move up and down.

[0033] The specific implementation of this embodiment is as follows: while utilizing the power provided by the rotating motor 2114 to make the vacuum suction cup 2105 fit tightly and fix to the patient's body surface, the stabilizing cylinder 2204 is manually set inside the upper limit frame 2203 and the lower limit frame 2215, so that the stabilizing cylinder 2204 can slide inside the upper limit frame 2203 and the lower limit frame 2215, and the upper limit frame 2203 and the lower limit frame 2215 are connected to the mounting frame 2101 by utilizing the limiting connecting rod 2202 and the connecting reinforcement plate 2201, so that the clamping and stabilizing unit 22 can be connected to the connecting and mounting unit 21, and then the sliding frame 2113 is moved upward, and the clamping ring 2210 is connected to the sliding frame 2113 by utilizing the moving plate 2209, and the clamping ring 2210 is further connected to the sliding frame 211 by the first connecting rod 2212, the positioning slip ring 2213 and the second connecting rod 2214. 3, and at the same time, the positioning slip ring 2213 slides along the outer surface of the limiting connecting rod 2202, and slides along the outer surface of the stabilizing tube 2204 through the clamping ring 2210. Since a plurality of compressible clamping buckles 2211 are fixed on the inner wall of the clamping ring 2210, and the conical ring 2208 is fixed on the outer surface of the stabilizing tube 2204, the clamping buckles 2211 and the conical ring 2208 can be squeezed to make the clamping ring 2210 clamp the stabilizing tube 2204 tightly and firmly, until the clamping ring 2210 can contact the bottom surface of the upper limit ring 2205, and the upper surface of the upper limit ring 2205 can contact the bottom surface of the upper limit frame 2203, so that the stabilizing tube 2204 can be firmly and stably clamped, so that the outer surfaces of the extension tube 13 and the ablation needle 14 can be stably clamped and limited, thereby avoiding the problem of position change between the discharge end electrodes of the component due to shaking of the component inserted into the target position of the patient. Embodiment 3

[0034] See also Figure 1-9 The present invention provides a technical solution: an irreversible electroporation ablation component with a movable electrode component. The present invention makes corresponding improvements to the technical problems mentioned in the background technology.

[0035] As a further limitation of the mounting clamping mechanism 2 of the present invention, a precise measuring mechanism 3 is provided on the back of the clamping and stabilizing unit 22. The precise measuring mechanism 3 is used in conjunction with the mounting clamping mechanism 2 to precisely measure the extension size of the irreversible electroporation ablation component.

[0036] The precise measuring mechanism 3 comprises a measuring fixed ring 301, the inner wall of which is fixedly connected to the outer surface of the ablation gun 11, the outer surface of the measuring fixed ring 301 is fixedly connected to a first measuring ruler 302, the interior of the first measuring ruler 302 is slidably connected to a first extension ruler 303, and the distance between the measuring fixed ring 301 fixed to the outer surface of the ablation gun 11 and the lower limit ring 2206 can be measured through the first measuring ruler 302 and the first extension ruler 303, thereby facilitating precise control of the extension movement size of the irreversible electroporation ablation component.

[0037] The outer surface of the lower limit ring 2206 is fixedly connected to the second measuring scale 304, and the second extension scale 305 is slidably connected inside the second measuring scale 304. The bottom surfaces of the first extension scale 303 and the second extension scale 305 are both fixedly connected to the lower base plate 306, and the bottom surface of one of the lower base plates 306 is in contact with the upper surface of the second measuring scale 304. The distance between the lower limit ring 2206 and the patient's body surface can be measured through the second measuring scale 304 and the second extension scale 305, thereby further facilitating the precise control of the extension movement size of the irreversible electroporation ablation component.

[0038] The back of the first measuring ruler 302, the back of the first extension ruler 303, the back of the second measuring ruler 304 and the back of the second extension ruler 305 are all fixedly connected with a precision scale 307. The precision scale 307 fixed on the surface of the first measuring ruler 302, the first extension ruler 303, the second measuring ruler 304 and the second extension ruler 305 facilitates reading of the dimensions of the first measuring ruler 302, the first extension ruler 303, the second measuring ruler 304 and the second extension ruler 305, thereby facilitating accurate reading of the extended movement dimension of the irreversible electroporation ablation component.

[0039] The specific implementation of this embodiment is as follows: after the ablation gun 11, the handle 12, the extension tube 13, the ablation needle 14 and the ablation electrode 15 are clamped and fixed to form the main body of the irreversible electroporation ablation assembly, it is necessary to manually pull the second extension ruler 305 in the second measuring ruler 304 to enable the second extension ruler 305 to slide in the second measuring ruler 304, and read the precise scale 307 fixed on one side of the second measuring ruler 304 and the second extension ruler 305 to read the fixed lower part of the stabilizing tube 2204. The distance between the limiting ring 2206 and the patient's body surface is determined by manually pulling the lower bottom plate 306 to make the first extension ruler 303 slide in the first measuring ruler 302 until the bottom surface of the lower bottom plate 306 contacts the upper surface of the second measuring ruler 304, thereby reading the first measuring ruler 302 and the precise scale 307 fixed on one side of the first extension ruler 303 to read the distance between the measuring fixing ring 301 fixed to the outside of the melting gun 11 and the body surface of the lower limiting ring 2206, and thus accurately reading the distance between the measuring fixing ring 301 fixed to the outside of the melting gun 11 and the body surface of the lower limiting ring 2206. The distance between the fixed ring 301 and the patient's body surface can be accurately read by manually holding the handle 12 to slide the extension tube 13 in the stabilizing tube 2204 through the ablation gun 11, and the ablation needle 14 fixedly connected under the extension tube 13 can slide in the sliding positioning tube 2207 until the bottom end of the ablation needle 14 contacts the patient's skin surface. At this time, the distance between the fixed ring 301 fixed outside the ablation gun 11 and the patient's body surface can be accurately read by manually holding the handle 12 to push the ablation gun 11. The distance that the needle 14 extends into the patient's body can further enable the irreversible electroporation ablation component to be used accurately in the patient's body until the ablation electrode 15 in the ablation needle 14 is extended and distributed around the patient's tumor cells. By controlling the irreversible electroporation ablation component, the electric pulses propagating between the multiple ablation electrodes 15 form "nanopores" in the cell membrane. If the applied current reaches a certain threshold, these nanopores will become permanent, thereby causing cell death. Irreversible electroporation has been proven to effectively and safely destroy tumor cells.

[0040] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0041] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An irreversible electroporation ablation assembly with a movable electrode assembly, comprising an ablation assembly body (1), characterized in that: The ablation assembly body (1) comprises an ablation gun (11), the upper surface of the ablation gun (11) is fixedly connected to a handle (12), the bottom surface of the ablation gun (11) is fixedly connected to an extension tube (13), the bottom surface of the extension tube (13) is fixedly connected to an ablation needle (14), the interior of the ablation needle (14) and the interior of the extension tube (13) are slidably connected to a plurality of ablation electrodes (15), and a mounting clamping mechanism (2) is provided below the ablation gun (11); The mounting clamping mechanism (2) comprises a connecting and mounting unit (21), the connecting and mounting unit (21) being located below the ablation gun (11), and the connecting and mounting unit (21) being used to stably mount the irreversible electroporation ablation component on the patient's body surface; The installation clamping mechanism (2) comprises a clamping and stabilizing unit (22), the clamping and stabilizing unit (22) being located outside the extension tube (13), the connection installation unit (21) being used in conjunction with the clamping and stabilizing unit (22), the clamping and stabilizing unit (22) being used to stably clamp the irreversible electroporation ablation component; A precise measuring mechanism (3) is provided on the back of the clamping and stabilizing unit (22). The precise measuring mechanism (3) is used in conjunction with the mounting clamping mechanism (2). The precise measuring mechanism (3) is used to precisely measure the extension size of the irreversible electroporation ablation component.

2. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 1, characterized in that: The connecting and mounting unit (21) comprises a mounting frame (2101), wherein the mounting frame (2101) is arranged outside the ablation needle (14), and the bottom surface of the mounting frame (2101) is fixedly connected with four support tubes (2102), and the interior of each support tube (2102) is slidably connected with an extension tube (2103), and the outer surface of each support tube (2102) and the outer surface of each extension tube (2103) are threadedly connected with a tightening nut (2104), and the bottom surface of each extension tube (2103) is movably hinged with a vacuum suction cup (2105), and the outer surface of each extension tube (2103) is fixedly connected with a connecting tube. (2106), the bottom end of each of the connecting tubes (2106) penetrates the vacuum suction cup (2105) and extends to the interior of the vacuum suction cup (2105), the upper surface of the mounting frame (2101) is fixedly connected to an exhaust pipe (2108), the top end of each of the extension tubes (2103) is fixedly connected to the outer surface of the exhaust pipe (2108) through a telescopic hose, the upper surface of the mounting frame (2101) is fixedly connected to a vacuum pipe (2111), the ends of the exhaust pipes (2108) that are close to each other are fixedly connected to the outer surface of the vacuum pipe (2111), and the outer surface of the mounting frame (2101) is fixedly connected to a connecting frame (2 109), the upper surface of the connecting frame (2109) is fixedly connected to four limiting cylinders (2110), a rotating motor (2114) is arranged above the connecting frame (2109), the bottom surface of the rotating motor (2114) is in contact with the top of the vacuum tube (2111), the outer surface of the rotating motor (2114) is fixedly connected to a sliding frame (2113), the bottom surface of the sliding frame (2113) is fixedly connected to four limiting columns (2112), the four limiting columns (2112) are respectively slidably connected to the inside of the four limiting cylinders (2110), and the output end of the rotating motor (2114) is fixedly connected to a rotating shaft (2 115), a rotating disk (2116) is fixedly connected to the outer surface of the rotating shaft (2115), and the rotating disk (2116) is rotatably connected to the inside of the vacuum tube (2111), and a guide sliding block (2117) is fixedly connected to the outer surface of the rotating disk (2116), and a guide sliding groove (2119) is provided on the inner wall of the vacuum tube (2111), and the guide sliding block (2117) is slidably connected to the inner cavity of the guide sliding groove (2119), and a silicone piston (2118) is fixedly connected to the bottom end of the rotating shaft (2115), and the silicone piston (2118) is slidably connected to the inside of the vacuum tube (2111).

3. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 2, characterized in that: The outer surface of each vacuum suction cup (2105) is adhered with medical tapes (2107) arranged in a circumferential manner at equal distances, and the adhesive surface of each medical tape (2107) is adhered to the patient's body surface.

4. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 2, characterized in that: The clamping and stabilizing unit (22) comprises a stabilizing cylinder (2204), the extension cylinder (13) is slidably connected to the interior of the stabilizing cylinder (2204), an upper limit frame (2203) is sleeved on the exterior of the stabilizing cylinder (2204), four limit connecting rods (2202) are fixedly connected to the bottom surface of the upper limit frame (2203), four connecting reinforcement plates (2201) are fixedly connected to the inner wall of the mounting frame (2101), the bottom ends of the four limit connecting rods (2202) are respectively fixedly connected to the upper surfaces of the four connecting reinforcement plates (2201), and the stabilizing cylinder (2204) The outer surfaces of the upper limit ring (2205) and the conical ring (2208) are respectively fixedly connected, the bottom surface of the upper limit ring (2205) is fixedly connected to the upper surface of the conical ring (2208), the back surface of the sliding frame (2113) is fixedly connected to a moving plate (2209), the back surface of the moving plate (2209) is fixedly connected to a clamping ring (2210), the inner wall of the clamping ring (2210) is fixedly connected to clamping buckles (2211) arranged at equal distances, and the side surfaces of a plurality of the clamping buckles (2211) that are close to each other are in contact with the outer surface of the conical ring (2208).

5. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 4, characterized in that: A lower limit frame (2215) is fixedly connected to one side of the four connecting reinforcement plates (2201) that are close to each other, and the outer surface of the stabilizing cylinder (2204) is in contact with the inner wall of the lower limit frame (2215).

6. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 5, characterized in that: A lower limiting ring (2206) is provided above the lower limiting frame (2215), and the inner wall of the lower limiting ring (2206) is fixedly connected to the outer surface of the stabilizing cylinder (2204).

7. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 4, characterized in that: The bottom surface of the stabilizing cylinder (2204) is fixedly connected to a sliding positioning cylinder (2207), and the ablation needle (14) is slidably connected to the interior of the sliding positioning cylinder (2207).

8. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 4, characterized in that: Both side surfaces of the sliding frame (2113) are fixedly connected to first connecting rods (2212); the ends of the two first connecting rods (2212) that are away from each other are fixedly connected to positioning slip rings (2213); the inner walls of the two positioning slip rings (2213) are respectively in contact with the outer surfaces of two of the limiting connecting rods (2202); the outer surface of each positioning slip ring (2213) is fixedly connected to a second connecting rod (2214); the ends of the two second connecting rods (2214) that are close to each other are fixedly connected to the outer surface of the clamping ring (2210).

9. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 6, characterized in that: The precise measuring mechanism (3) comprises a measuring fixing ring (301), the inner wall of which is fixedly connected to the outer surface of the ablation gun (11), the outer surface of the measuring fixing ring (301) is fixedly connected to a first measuring ruler (302), the interior of the first measuring ruler (302) is slidably connected to a first extension ruler (303), the outer surface of the lower limit ring (2206) is fixedly connected to a second measuring ruler (304), the interior of the second measuring ruler (304) is slidably connected to a second extension ruler (305), and the back sides of the first measuring ruler (302), the first extension ruler (303), the second measuring ruler (304) and the second extension ruler (305) are all fixedly connected to a precise scale ruler (307).

10. The irreversible electroporation ablation assembly with a movable electrode assembly according to claim 9, characterized in that: The bottom surface of the first extension ruler (303) and the bottom surface of the second extension ruler (305) are both fixedly connected to a lower bottom plate (306), wherein the bottom surface of one of the lower bottom plates (306) is in contact with the upper surface of the second measuring ruler (304).

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