Skin care composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of medical care, in particular to a skin care composition as well as a preparation method and application thereof. The skin care composition is prepared from the following raw materials in percentage by mass: 0.05 to 5.0 percent of herba eupatorii extract, 0.01 to 2.0 percent of saussurea involucrata extract, 0.01 to 3.0 percent of bergamot extract and 90.0 to 99.93 percent of auxiliary materials. According to the skin care composition, the fortune eupatorium herb extract, the saussurea involucrata extract and the bergamot extract serve as main effective components, and the skin care composition can be used for treating formed bedsores and can also play a role in preventing long-term bedridden patients who do not form bedsores; the skin care composition is simple and convenient in preparation method, low in price and convenient in daily use, and greatly reduces the nursing work. And the traditional Chinese medicine composition also has effects on dry and chapped skin, eczema, diabetic foot and the like with similar diseases.

Description

Technical Field

[0001] The present invention relates to the technical field of medical care, and in particular to a skin care composition, a preparation method thereof and an application thereof. Background Art

[0002] Bedsores, also known as pressure sores or pressure ulcers, are a type of chronic ulcer disease caused by the weight and friction of the body in patients who are bedridden for a long time. Bedsores themselves are not a disease. They are mostly caused by skin damage due to other primary diseases that have not been properly cared for. The causes of bedsores are relatively complex. Malnutrition, old age, the impact of diseases, and long-term tissue pressure can all induce bedsores. Malnutrition and long-term bed rest can cause local tissue qi stagnation and blood stasis, which in turn aggravates the thinning of skin tissue and damage to the skin barrier, causing the skin to dry and peel, or ulcerate and necrotize.

[0003] At present, the treatment of bedsores is preferably external medication, which mainly includes Chinese medicine ointment, Western medicine ointment and medical dressing. However, these treatment methods all have certain technical problems in practical application.

[0004] In terms of traditional Chinese medicine ointments, although they are mainly composed of natural herbs, most of them use irritating solvents such as ethanol to extract traditional Chinese medicine materials during the preparation process, which is easy to leave residues and cause contact irritation. At the same time, the preparation method is complicated and cumbersome, and it is difficult to control the quality of each batch, and the efficacy is difficult to guarantee. In addition, the ointment has a strong smell and dark color, which can easily stain clothes and beds, which not only increases the difficulty of nursing, but also reduces the patient's experience.

[0005] Western medicine ointments are mainly used for antibacterial and anti-inflammatory purposes, aiming to prevent secondary infection. However, these drugs are highly irritating to the wound surface, and their active ingredients are generally hormones and antibiotics, which can easily lead to drug resistance after long-term use. This not only limits the scope of drug use, but also increases the treatment risk for patients.

[0006] As for medical dressings, there are few dressings specifically for bedsores. Generally, common clinical dressings are used, such as hydrocolloid dressings and foam dressings. Although these dressings can absorb exudate, they are expensive and their main function is to absorb exudate, but they have poor effects on wound healing. At the same time, it is not easy to observe the wound surface, and dressing changes may cause tearing and pain, which also brings many inconveniences to the patient's treatment.

[0007] The current technical routes to solve the above technical problems mainly revolve around improving drug ingredients, optimizing preparation methods, and developing new dressings. However, these technical routes still have some defects in practical applications. For example, in terms of drug ingredients, although herbal ingredients with antibacterial and anti-inflammatory effects and promoting wound healing can be screened out, how to effectively extract and control their quality remains a difficult problem. In terms of preparation methods, although the preparation process can be simplified, how to ensure the consistency and stability of the efficacy of each batch of products still needs further research. In terms of the development of new dressings, although some new dressings with better exudate absorption performance have been launched, how to take into account the wound healing effect, easy observation, convenience of dressing change, and cost-effectiveness at the same time still needs to be explored.

[0008] To this end, the present application provides a skin care composition, a preparation method thereof, and an application thereof. Summary of the invention

[0009] The present application provides a skin care composition, a preparation method and an application thereof. The skin care composition has perilla extract, snow lotus extract and bergamot extract as main effective ingredients. The skin care composition can treat bedsores that have already formed, and can also prevent bedsores for long-term bedridden patients who have not yet formed bedsores. The preparation method of the skin care composition is simple, low-priced, and convenient for daily use, which greatly reduces the nursing work. The skin care composition can also be used as a daily skin protection product for dry, cracked skin, eczema, diabetic foot and the like with similar symptoms.

[0010] The technical solution adopted by this application to solve its technical problem is:

[0011] In a first aspect, the present application provides a skin care composition, comprising the following raw materials by mass percentage:

[0012] Perilla extract: 0.05-5.0%

[0013] Tianshan Snow Lotus Extract: 0.01-2.0%

[0014] Bergamot extract: 0.01-3.0%

[0015] Excipients: 90.0-99.93%.

[0016] In one or more embodiments, the content of nerol acetate in the Perilla frutescens extract is not less than 0.05%, and the content of thymol methyl ether is not less than 0.04%.

[0017] In one or more embodiments, the alkaloid content of the Tianshan Snow Lotus extract is 0.05%-0.2%, and the content of flavonoids and phenols is 0.1-0.25%.

[0018] In one or more embodiments, the total active content of bergamot lactone and limonolactone in the bergamot extract is not less than 0.2%.

[0019] In one or more embodiments, the adjuvant includes sunflower seed oil.

[0020] In one or more embodiments, the following raw materials are included by mass percentage:

[0021] Perilla extract: 0.05-5.0%

[0022] Tianshan Snow Lotus Extract: 0.01-2.0%

[0023] Bergamot extract: 0.01-3.0%

[0024] Tocopherol: 0.2-0.5%.

[0025] Sweet almond oil: 10.0-15.0%

[0026] Sunflower seed oil: 74.5-89.73%.

[0027] In a second aspect, the present application provides a method for preparing a skin care composition according to the first aspect, comprising the following steps:

[0028] Calculate and weigh each raw material according to the mass percentage of the skin care composition; and fully mix all the raw materials in sequence to obtain a skin care composition.

[0029] In a third aspect, there is provided an application of the composition described in the present application in the preparation of daily skin protection products or in the preparation of products for the treatment and prevention of bedsores.

[0030] Specifically, the skin care composition has the effects of moisturizing, nourishing and repairing the skin.

[0031] Specifically, the skin care composition has the effects of promoting blood circulation, repairing wound surface, improving pigmentation, inhibiting bacteria and deodorizing on bedsores.

[0032] The beneficial effects of this application are:

[0033] The skin care composition described in the present application uses perilla extract, snow lotus extract and bergamot extract as main active ingredients and is prepared into a skin care composition; the skin care composition can be used as daily care for patients with bedsores, adopts a full oil system, has good affinity and permeability to the skin, and is gentle and non-irritating; the skin care composition can promote blood circulation, nourish the skin, repair wounds, improve pigmentation, inhibit bacteria and deodorize, relieve itching and relieve pain, and has no drug resistance and toxic side effects after long-term use.

[0034] The preparation method of the skin care composition is simple, the price is low, and it is convenient for daily use, which greatly reduces the care work; and the skin care composition is also effective for dry and cracked skin, eczema, diabetic foot and the like with similar symptoms. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0036] Figure 1 Results of multiple skin irritation tests;

[0037] Figure 2 This is a schematic diagram of Case 1 before using the skin care composition described in the present application;

[0038] Figure 3 This is a schematic diagram of case 1 after using the skin care composition described in the present application;

[0039] Figure 4 This is a schematic diagram of Case 2 before using the skin care composition described in the present application;

[0040] Figure 5 This is a schematic diagram of case 2 after using the skin care composition described in the present application;

[0041] Figure 6 This is a schematic diagram of Case 3 before using the skin care composition described in the present application;

[0042] Figure 7 This is a schematic diagram of case 3 after using the skin care composition described in the present application;

[0043] Figure 8 Test indicators and instruments for moisturizing, nourishing and repairing tests for this application;

[0044] Fig. 9 The test results for moisturizing, nourishing and repairing. DETAILED DESCRIPTION

[0045] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0046] In this application, the term "and / or" describes the association relationship of associated objects, indicating that there may be three relationships. For example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. A and B can be singular or plural. The character " / " generally indicates that the associated objects are in an "or" relationship.

[0047] In the present application, "at least one" means one or more, and "plurality" means two or more. "At least one of the following" or similar expressions refers to any combination of these items, including any combination of single items or plural items. For example, "at least one of a, b, or c", or "at least one of a, b, and c" can all represent: a, b, c, ab (i.e., a and b), ac, bc, or abc, where a, b, and c can be single or multiple, respectively.

[0048] It should be understood that in the various embodiments of the present application, the size of the serial numbers of the above-mentioned processes does not mean the order of execution, some or all of the steps can be executed in parallel or sequentially, and the execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

[0049] The terms used in the embodiments of the present application are only for the purpose of describing specific embodiments, and are not intended to limit the present application. The singular forms "a", "said" and "the" used in the embodiments of the present application and the appended claims are also intended to include plural forms, unless the context clearly indicates other meanings.

[0050] The weight of the relevant components mentioned in the embodiment description of the present application can not only refer to the specific content of each component, but also represent the proportional relationship between the weights of the components. Therefore, as long as the content of the relevant components is proportionally enlarged or reduced according to the embodiment description of the present application, it is within the scope disclosed in the embodiment description of the present application. Specifically, the mass described in the embodiment description of the present application can be a mass unit known in the chemical industry such as μg, mg, g, kg, etc.

[0051] The terms "first" and "second" are used only for descriptive purposes to distinguish objects such as substances from each other, and should not be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. For example, without departing from the scope of the embodiments of the present application, the first XX may also be referred to as the second XX, and similarly, the second XX may also be referred to as the first XX. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0052] The present application provides a skin care composition, which comprises the following raw materials by mass percentage:

[0053] Perilla extract: 0.05-5.0%

[0054] Tianshan Snow Lotus Extract: 0.01-2.0%

[0055] Bergamot extract: 0.01-3.0%

[0056] Tocopherol: 0.2-0.5%.

[0057] Sweet almond oil: 10.0-15.0%

[0058] Sunflower seed oil: 74.5-89.73%.

[0059] In some embodiments, the content of active ingredients in the Perilla frutescens extract: nerol acetate is not less than 0.05%, and thymol methyl ether is not less than 0.04%.

[0060] Specifically, the content of active ingredients in the Perilla extract: nerol acetate is 0.5-1%, and the content of thymol methyl ether is 2-3%.

[0061] Specifically, in the skin care composition, the mass content of the Perilla frutescens extract can be any value among 0.05%, 0.1%, 1%, 3%, and 5%, that is, within the range of 0.05-5.0% (including the endpoint values).

[0062] It is understandable that Perilla is the above-ground part of the Perilla plant of the genus Perilla in the Asteraceae family, also known as vanilla, small Ze Lan, large Ze Lan, and chicken bone fragrance. It tastes slightly bitter and is cold in nature. It has the effects of clearing away heat and relieving summer heat, aromatic dehumidification, insecticidal and antibacterial. Among them, active ingredients such as nerol acetate and thymol methyl ether can effectively inhibit bacteria and reduce inflammation on bedsore wounds.

[0063] In some embodiments, the content of alkaloids in the extract of Saussurea involucrata is 0.05%-0.2%, and the content of flavonoids and phenols is 0.1-0.25%. Specifically, in the skin care composition, the mass content of the extract of Saussurea involucrata can be any value among 0.01%, 0.1%, 1%, and 2%, that is, within the range of 0.01-2.0% (including the endpoint values).

[0064] Understandably, Tianshan Saussurea, also known as "Snow Lotus", is called "Tage Yilis" in Uyghur. It is a perennial herb. It grows on the steep cliffs and ice-stained rock cracks at an altitude of about 4,000 meters in the Tianshan Mountains. The climate there is extremely cold, and the snow does not melt all year round. Ordinary plants cannot survive at all, but Saussurea can grow tenaciously in the severe cold of dozens of degrees below zero and the thin air and hypoxic environment. This unique survival habit and unique growth environment make it natural and rare, and create its unique pharmacological effects and magical medicinal value. People regard Saussurea as the "king of herbs" and "the best medicine". In addition to removing cold phlegm, warming the uterus and dispersing blood stasis, and promoting blood circulation in patients, the extract of Tianshan Saussurea can also improve the cell repair ability of the wound surface and inhibit pigmentation after wound repair.

[0065] Specifically, the snow lotus is selected from the steep cliffs at an altitude of about 4,000 meters in the Tianshan Mountains of Xinjiang Uygur Autonomous Region. The main active ingredients are volatile oils, alkaloids, flavonoids, phenols, sugars, tannins, etc., among which the alkaloid content is controlled at 0.05%-0.2%, and the flavonoids and phenols are controlled at 0.1-0.25%.

[0066] In some embodiments, the total active content of bergamot lactone and citronellol lactone in the bergamot extract is not less than 0.2%.

[0067] Understandably, bergamot extract has a strong fruity aroma, which can provide a refreshing fragrance, improve the patient's body odor, promote the metabolism of skin herpes, swelling, etc., and relieve pain and itching.

[0068] Specifically, in the skin care composition, the mass content of the bergamot extract can be any value among 0.01%, 0.1%, 1%, and 3%, that is, within the range of 0.01-3.0% (including the endpoint values).

[0069] Specifically, the bergamot extract is selected from the Calabria region of Italy, wherein the total active content of bergamot lactone and limonolactone is 5-6%.

[0070] In some embodiments, in the skin care composition, the mass content of tocopherol can be any value among 0.2%, 0.3%, 0.4%, and 0.5%, that is, within the range of 0.2-0.5% (including the endpoint values).

[0071] In some embodiments, in the skin care composition, the mass content of sweet almond oil can be any value among 10%, 11%, 12%, and 15%, that is, within the range of 10.0-15.0% (including the endpoint values).

[0072] In some embodiments, in the skin care composition, the mass content of sunflower seed oil can be any value among 74.5%, 80%, 85%, and 89.73%, that is, within the range of 74.5-89.73% (including the endpoint values).

[0073] The skin care composition described in the present application is further described through the following examples, comparative groups and blank groups.

[0074] The raw material compositions of the skin care compositions of Example 1, Example 2, Comparative Groups 1, 2, 3 and the blank group are shown in Table 1 below:

[0075] Table 1 Raw materials and their mass contents of skin care compositions

[0076]

[0077]

[0078] The reagents and raw materials used above are all commercially available; the mass content of nerol acetate in the perilla extract is not less than 0.05%, and the content of thymol methyl ether is not less than 0.04%; the alkaloid content in the Tianshan Snow Lotus extract is controlled at 0.05%-0.2%, and the quality of flavonoids and phenols is controlled at 0.1-0.25%; the total active mass content of bergamot lactone and citronellol lactone in the bergamot extract is not less than 0.2%.

[0079] Preparation method of the above skin care composition:

[0080] S1. Prepare the production equipment and tools required for production, clean them with water, and then spray them with 75% alcohol for disinfection. The disinfectant alcohol is discharged from the discharge port, and the stirring pot is sealed and disinfected for 10 minutes before it can be put into use. All production tools must be disinfected for 10 minutes and confirmed to be free of any moisture before use.

[0081] S2. Calculate and weigh each raw material. Add all raw materials into the mixing pot in turn, start stirring at 20-30HZ speed, and continue stirring for at least 15 minutes until uniform.

[0082] S3. Take samples of semi-finished products to the inspection room for physical and chemical inspection. After passing the inspection, open the discharging valve of the mixing pot and discharge the materials into the corresponding semi-finished product storage. Fill with clean packaging materials, and finally get the finished products, pack them into boxes and put them into storage.

[0083] The following test was performed on Examples 1-2, Comparative Groups 1-3 and a blank group.

[0084] 1. Multiple skin irritation

[0085] This test is based on the "Technical Specification for Safety of Cosmetics" (2015 edition), and the test samples are Examples 1 and 2, Comparative Groups 1, 2, 3, and commercially available Chinese medicine ointments and commercially available Western medicine ointments. A total of 32 New Zealand rabbits were selected, 4 for each example, half male and half female, weighing 2.0-2.5 kg. The experimental animals were raised in single cages, and the animals were adapted to the experimental animal room environment for at least 3 days before the test.

[0086] About 24 hours before the test, the hair on both sides of the dorsal spine of the experimental animals was cut off, and the hair removal area was 3cm×3cm on each side. The application area was 2.5cm×2.5cm. Take 0.5mL of the test sample and apply it on the hairless skin on one side, and the hairless skin on the other side was used as a control. Apply once a day for 14 consecutive days. Starting from the second day, cut the hair before each application and use warm water to remove the residual test sample. Observe the results after 1 hour.

[0087] The average score is: 0-0.5 is non-irritating; 0.5-2.0 is mildly irritating; 2.0-6.0 is moderately irritating; 6.0-8.0 is strongly irritating.

[0088] The test results are as follows Figure 1 As shown: During the experiment, no abnormal symptoms were observed in the experimental animals.

[0089] from Figure 1 It can be seen that under the experimental conditions, the multiple skin irritations of the embodiment and the comparison group were non-irritating, and the commercially available Chinese medicine ointment and Western medicine ointment were mildly irritating. In the case of no irritation, the embodiment has a lower integral value than the comparison group, indicating that when the three extracts are combined together, they can play a better role. The above also shows that the present invention can be used safely and without irritation.

[0090] 2. Moisturizing, nourishing and repairing test

[0091] The nourishing, repairing and moisturizing effects on the skin are evaluated by testing four indicators: transepidermal water loss (TEWL value), skin hemoglobin content, skin elasticity R2 and skin gloss.

[0092] The test samples are Examples 1 and 2, Comparative Groups 1, 2, 3, and commercially available Chinese medicinal ointments and commercially available Western medicinal ointments. The number of test subjects is 80, with 10 test subjects in each test case. The test time is the first day of the subject's visit (D0) and the subject's use of the product for 28 days (D28). Test environment: temperature: 21±1°C; humidity: 50±10%RH.

[0093] 2.1 Test indicators and instruments, see Figure 8 .

[0094] 2.2 Test results, see Fig. 9 ;

[0095] Wherein: 1) Improvement rate (%) = (basic value - test value after using the product for 28 days) / basic value × 100%; 2) All the data of the tested samples were p < 0.001.

[0096] from Fig. 9 It can be seen that after the test samples were used for 28 days, the improvement effects of commercially available Chinese and Western medicine ointments were minimal; the embodiment group was significantly better than the control group and the blank group, and embodiment 2 was better than embodiment 1, indicating that when the three extracts are combined together, they can exert a better effect, and the higher the dosage, the better the effect.

[0097] Furthermore, this embodiment can repair damaged skin barriers, reduce epidermal water loss, improve dry skin, promote blood circulation around bedsores, improve blood stasis and redness, and promote blood circulation, nourish the skin, restore the skin's original healthy state, and thus improve the skin's elasticity and luster. The above data show that this embodiment has the effects of moisturizing, nourishing, and repairing the skin.

[0098] 3. Clinical use test

[0099] 3.1 60 patients with bedsores, aged between 60 and 80 years old, regardless of gender. The patients have received symptomatic supportive treatment and are not in life-threatening situations. The patients and their families understand the clinical treatment plan and voluntarily participate in this clinical study. The patient's wishes should be fully considered during the treatment process, and any questions the patient has should be answered in a timely manner.

[0100] The example and conventional treatment (control group) were compared, with 20 patients in each test case, and the treatment was continued for 28 days. The control group performed routine debridement on the patients with bedsores every day, and sterile gauze and the like could be used to absorb exudate as needed, without using other external ointments. On this basis, the example group applied nursing oil three times a day.

[0101] Criteria for judging efficacy: 1) Improvement, reduction in the area of ​​bedsores, and significant relief of other symptoms; 2) Cure: disappearance of symptoms and recovery; 3) The sum of improvement and cure is effective.

[0102] Experimental results:

[0103] Trial sample name Cured (case) Improvement (example) Effectiveness% Invalid (Example) Inefficiency % Example 1 0 15 75 5 25 Example 2 1 18 90 2 10 Control group 0 3 15 17 85

[0104] From the perspective of clinical application, the effective rates of Examples 1 and 2 are much higher than those of the control group, which is reflected in a higher improvement rate and a lower cure rate, and the effect of Example 2 is higher than that of Example 1.

[0105] 3.2 Typical Cases

[0106] Note: The skin care composition used below is that of Example 1.

[0107] Case 1: Male patient, age 71, due to "comprehensive treatment of liver cancer for more than 3 years". He had palpitations, chest tightness and dyspnea, and used high-flow oxygen inhalation. The patient could not lie flat, but sat up and lay down. He had poor sensation in the sacrum and coccyx, and diarrhea, which led to shallow ulcer-stage bedsores in the sacrum and coccyx, with an area of ​​10*12CM, and exudation of blood. Currently, he was rinsed with saline and dried, and then the skin care composition was evenly applied to the skin around the bedsore, three times a day, and covered with exudate absorption patches. The nursing staff reported that the product had a good texture, was easy to apply and evenly absorbed, and was not greasy. The patient reported that it could relieve pain. The comparison before and after use is shown in the figure below.

[0108] like Figure 2As shown, on the day of use: peripheral bleeding was obvious, the skin was dry and flaky, and red.

[0109] like Figure 3 As shown, after 28 days of use: peripheral bleeding decreased, the area of ​​bedsores decreased, and skin dryness and redness improved.

[0110] Case 2: Male patient, 72 years old, had a car accident injury on his left calf nearly 50 years ago, and the scar ruptured and did not heal after half a year of treatment in a military hospital. He had diabetes for 24 years, coronary heart disease for 24 years, premature beats for 10 years, and diabetic renal insufficiency for 5 years. The wound healed in three weeks. Venous ulcers of the lower limbs and seborrheic dermatitis of the surrounding skin, wound treatment + pressure therapy + skin oil surrounding skin care. The nursing staff reported that the patient's skin problems improved significantly after using the care oil. The dry and cracked skin and eczema around diabetic foot, venous ulcers, etc. were significantly improved, especially the senile eczema that had been itching for many years and the rash was useless with any medicine. This product is easy to use and has obvious curative effect. The patient reported that the use of the care oil can improve itching, is convenient for large areas, and is not easy to stain the bed, and there is no discomfort.

[0111] Before use Figure 4 As shown, the wound was ulcerated with exudate and bleeding, and the surrounding skin had small blisters and eczema-like features, and the skin was itchy and red.

[0112] After 28 days of use, Figure 5 Shown: The wound healed and the eczema-like changes in the surrounding skin improved significantly.

[0113] Case 3: Male patient, age 64, 30 years of diabetes, left fourth toe trauma infection for half a month, right lower limb artery occlusion in hospital balloon dilatation for more than a year. Left fourth toe infection ulcer, gangrene, bone destruction, myofascial space infection, amputation and debridement and drainage surgery 4 months after wound healing. Apply care oil three times a day. Nursing staff reported that the use of care oil significantly improved the dryness of the patient's feet, the effect is obvious; easy to apply, reducing nursing work. The patient reported that it can improve pain and no unpleasant odor.

[0114] Before use Figure 6 Shown: The peripheral skin is dry, with obvious dead skin and pigmentation.

[0115] After 28 days of use Figure 7 As shown: Peripheral skin dryness has been significantly improved, dead skin has been reduced, and pigmentation has been significantly improved.

[0116] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims

1. A skin care composition, characterized in that The following raw materials are included by mass percentage: Perilla extract: 0.05-5.0% Tianshan Snow Lotus Extract: 0.01-2.0% Bergamot extract: 0.01-3.0% Excipients: 90.0-99.93%.

2. A skin care composition according to claim 1, characterized in that: The content of nerol acetate in the perilla extract is not less than 0.05%, and the content of thymol methyl ether is not less than 0.04%.

3. A skin care composition according to claim 1, characterized in that: The content of alkaloids in the Tianshan Snow Lotus extract is 0.05%-0.2%, and the content of flavonoids and phenols is 0.1-0.25%.

4. A skin care composition according to claim 1, characterized in that: The total active content of bergamot lactone and citronellol lactone in the bergamot extract is not less than 0.2%.

5. A skin care composition according to claim 1, characterized in that: The auxiliary materials include sunflower seed oil.

6. A skin care composition according to claim 1, characterized in that: The following raw materials are included by mass percentage: Perilla extract: 0.05-5.0% Tianshan Snow Lotus Extract: 0.01-2.0% Bergamot extract: 0.01-3.0% Tocopherol: 0.2-0.5% Sweet almond oil: 10.0-15.0% Sunflower seed oil: 74.5-89.73%.

7. A method for preparing a skin care composition according to any one of claims 1 to 6, characterized in that: The following steps are involved: Calculate and weigh each raw material according to the mass percentage of the skin care composition; and fully mix all the raw materials in sequence to obtain a skin care composition.

8. Use of the skin care composition according to any one of claims 1 to 6 in the preparation of daily skin protection products or in the preparation of products for treating and preventing bedsores.

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