Traditional plaster containing xanthoceras sorbifolia bunge component and preparation method thereof

Abstract

The invention relates to a traditional plaster containing a shiny-leaved yellowhorn component and a preparation method of the traditional plaster. The plaster is prepared from xanthoceras sorbifolia bunge oil, fruit tree, various traditional Chinese medicinal materials and auxiliary materials, has the effects of dispelling wind and eliminating dampness, relieving swelling and pain and strengthening tendons and bones, and is particularly suitable for treating rheumatism, arthritis and various pain diseases. The preparation method comprises the steps of oil extraction, medicinal material selection, crushing, extraction, mixing and the like, and the prepared plaster is fine and smooth in texture and remarkable in medicine effect.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional old plaster for external application treatment and a preparation method thereof. Background Art

[0002] As a treasure of traditional Chinese medicine, Chinese medicine has a long history and remarkable curative effect. As a common external application treatment method, traditional old plaster is deeply loved by patients because of its unique efficacy and convenient use method. However, the existing traditional old plaster has certain limitations in formula and preparation method. For example, in order to mix medicinal materials, vegetable oils or edible oil components such as rapeseed oil, soybean oil, peanut oil are usually used as matrix to moisturize and assist the penetration of drug components, but this matrix oil has no synergistic effect with the Chinese medicinal materials themselves, resulting in insufficient efficacy. In addition, during the application of traditional old plasters, patients' allergic phenomena are also relatively common. Therefore, the present invention aims to provide a traditional old plaster mainly containing Xanthoceras sorbifolia components and a preparation method thereof to solve the above problems. Summary of the invention

[0003] 1. A traditional plaster containing Xanthoceras sorbifolia ingredients, characterized in that the plaster is made of the following raw materials in parts by weight: 200-1000 parts of Xanthoceras sorbifolia oil, 10-60 parts of Xanthoceras sorbifolia wood, 10-30 parts of Herba Polygoni Multiflori, 5-15 parts of vinegar Cyperus rotundus, 5-20 parts of Angelica dahurica, 1-3 parts of processed Chuanwuji, 1-3 parts of processed Aconitum kusnezoffii, 1-3 parts of iron club, 5-20 parts of salt Psoralea corylifolia, 10-30 parts of rhubarb, 5-20 parts of vinegar frankincense, 5-20 parts of vinegar myrrh, 5-30 parts of Northern Liujinu; 5-20 parts of vinegar Curcuma aromatica, 1-5 parts of Sanguisorba officinalis, and 1-5 parts of Borneol.

[0004] 2. A method for preparing a traditional ointment as claimed in claim 1, characterized in that: it is prepared according to the following steps:

[0005] (1) Select high-quality Xanthoceras sorbifolia fruits and fruit trees.

[0006] (2) Extract pure Xanthoceras sorbifolia oil from Xanthoceras sorbifolia fruits by cold pressing; cut Xanthoceras sorbifolia wood (branches) into several small sections.

[0007] (3) Boil the squeezed Xanthoceras sorbifolia oil and the cut Xanthoceras sorbifolia wood in corresponding proportions for 30 minutes until the mixture turns brown, then remove and set aside.

[0008] (4) Grind Radix Polygoni Multiflori, vinegar-cured Cyperus rotundus, Angelica dahurica, processed Chuanwu, processed Caowu, iron mallet, salted Psoralea corylifolia, rhubarb, vinegar-cured frankincense, vinegar-cured myrrh, Ligusticum wallichii, vinegar-curcuma, Sanguisorba officinalis, and borneol into fine powder, and mix them evenly into fine medicinal powder.

[0009] (5) stirring and boiling the fine powder in step (4) and the mixture in step (3); when the oil temperature rises to 300° C., stopping heating, cooling, filtering, and boiling the filtered mixture for a second time over a low fire until it drips into beads, that is, a drop of plaster drips into cold water and can quickly solidify in the water and form round, non-spreading, and elastic beads, and then stopping heating;

[0010] (6) Stir-fry the auxiliary material Guangdan until dry, sieve it, add the sieved Guangdan to the medicinal oil, add the material for 5-10 minutes, and then stir at a speed of 200-400 r / min. Stop stirring when the medicinal oil changes from yellowish brown to dark brown, so that the thick paste is formed;

[0011] (7) Soak the thick paste in cold water for 3-7 days to obtain a detoxified ointment.

[0012] (8) Put the mixed ointment into a container and seal it for storage.

[0013] 3. An external application patch comprising the traditional ointment as claimed in claim 1.

[0014] Beneficial Effects

[0015] The theoretical basis of the traditional old plaster containing Xanthoceras sorbifolia ingredients of the present invention comes from Li Shizhen's "Compendium of Materia Medica" "Xanthoceras sorbifolia, also known as longevity fruit, fairy fruit, tree branches decoction plaster, dispel rheumatism, strengthen bones and muscles." Combined with modern research on the ten major pharmacological effects of Xanthoceras sorbifolia oil, it focuses on the effects of dispelling wind and dampness, reducing swelling and relieving pain, and is particularly suitable for the treatment of diseases such as rheumatoid arthritis. Compared with the existing traditional old plaster, firstly, using Xanthoceras sorbifolia oil as a matrix, on the one hand, the moisturizing and penetrating effect of traditional ointments is retained, on the other hand, Xanthoceras sorbifolia oil itself has good effects of dispelling wind and dampness, reducing swelling and relieving pain, and exerts its effects together with the effective ingredients of Xanthoceras sorbifolia and other Chinese medicinal materials, and has more significant medicinal effects than traditional ointments. Secondly, the mixture of various Chinese medicines and Xanthoceras sorbifolia oil is appropriately proportioned, which can reduce discomfort symptoms such as allergies, and Xanthoceras sorbifolia oil can penetrate the cell membrane to reduce the release of histamine, thereby playing an anti-allergic effect. At the same time, Xanthoceras sorbifolia oil is rich in unsaturated fatty acids and a variety of trace elements, which can enhance the immunity of the human body. DETAILED DESCRIPTION

[0016] Embodiment 1: A traditional plaster containing Xanthoceras sorbifolia ingredients, comprising 500 parts of Xanthoceras sorbifolia oil, 30 parts of Xanthoceras sorbifolia wood, 20 parts of Herba Polygoni Multiflori, 10 parts of vinegar Cyperus rotundus, 10 parts of Angelica dahurica, 2 parts of processed Chuanwu, 2 parts of processed Aconitum kusnezoffii, 2 parts of iron club, 10 parts of salt Psoralea corylifolia, 20 parts of rhubarb, 10 parts of vinegar frankincense, 10 parts of vinegar myrrh, 20 parts of Northern Liujinu; 10 parts of vinegar Curcuma aromatica, 3 parts of Sanguisorba officinalis, and 3 parts of Borneol.

[0017] Embodiment 2: A traditional plaster containing Xanthoceras sorbifolia ingredients, comprising 200 parts of Xanthoceras sorbifolia oil, 10 parts of Xanthoceras sorbifolia wood, 10 parts of Herba Polygoni Multiflori, 5 parts of vinegar Cyperus rotundus, 5 parts of Angelica dahurica, 1 part of processed Chuanwu, 1 part of processed Aconitum kusnezoffii, 1 part of iron club hammer, 5 parts of salt Psoralea corylifolia, 10 parts of rhubarb, 5 parts of vinegar frankincense, 5 parts of vinegar myrrh, 5 parts of Northern Liujinu; 5 parts of vinegar Curcuma aromatica, 1 part of Sanguisorba officinalis, and 1 part of Borneol.

[0018] Embodiment 3: A traditional plaster containing Xanthoceras sorbifolia ingredients, comprising 1000 parts of Xanthoceras sorbifolia oil, 60 parts of Xanthoceras sorbifolia wood, 30 parts of Herba Polygoni Multiflori, 15 parts of vinegar Cyperus rotundus, 20 parts of Angelica dahurica, 3 parts of processed Chuanwu, 3 parts of processed Aconitum kusnezoffii, 3 parts of iron club, 20 parts of salt Psoralea corylifolia, 30 parts of rhubarb, 20 parts of vinegar frankincense, 20 parts of vinegar myrrh, 30 parts of Northern Liujinu; 20 parts of vinegar Curcuma aromatica, 5 parts of Sanguisorba officinalis, and 5 parts of Borneol.

[0019] The above ointment is prepared according to the following steps:

[0020] (1) Select high-quality Xanthoceras sorbifolia fruits and fruit trees.

[0021] (2) Extract pure Xanthoceras sorbifolia oil from Xanthoceras sorbifolia fruits by cold pressing; cut Xanthoceras sorbifolia wood (branches) into several small sections.

[0022] (3) Boil the squeezed Xanthoceras sorbifolia oil and the cut Xanthoceras sorbifolia wood in corresponding proportions for 30 minutes until the mixture turns brown, then remove and set aside.

[0023] (4) Grind Radix Polygoni Multiflori, vinegar-cured Cyperus rotundus, Angelica dahurica, processed Chuanwu, processed Caowu, iron mallet, salted Psoralea corylifolia, rhubarb, vinegar-cured frankincense, vinegar-cured myrrh, Ligusticum wallichii, vinegar-curcuma, Sanguisorba officinalis, and borneol into fine powder, and mix them evenly into fine medicinal powder.

[0024] (5) stirring and boiling the fine powder in step (4) and the mixture in step (3); when the oil temperature rises to 300° C., stopping heating, cooling, filtering, and boiling the filtered mixture for a second time over a low fire until a drop of plaster is dropped into cold water and can solidify quickly in the water to form round, non-spreading, elastic beads, and then stopping heating;

[0025] (6) Stir-fry the auxiliary material Guangdan until dry, sieve it, add the sieved Guangdan to the medicinal oil, add the material for 5-10 minutes, and then stir at a speed of 200-400 r / min. Stop stirring when the medicinal oil changes from yellowish brown to dark brown, so that the thick paste is formed;

[0026] (7) Soak the thick paste in cold water for 3-7 days to obtain a detoxified ointment.

[0027] (8) Put the mixed ointment into a container and seal it for storage.

[0028] The above parts are all parts by weight.

[0029] An external application patch is used for dispelling wind and dampness, reducing swelling and relieving pain. The above-mentioned ointment is placed on the external application patch and applied to the affected part of the patient.

[0030] Ointment performance data

[0031] 70 patients with rheumatoid arthritis in Zhengzhou City and surrounding counties of Henan Province were selected for clinical observation and treatment, including 25 males and 45 females, aged 37 to 60 years old, with an average age of 47 years old. Main symptoms: migratory pain in multiple joints, joint swelling and pain, and joint inactivity in severe cases; the pain is obviously related to climate change, aggravated by cold or touching cold water, and relieved in sunny or warm weather.

[0032] The above patients were randomly and evenly divided into two experimental groups, each with 35 people, namely a treatment group and a control group. The control group was treated with a rheumatism bone pain patch produced by a pharmaceutical factory; the treatment group was treated with the Chinese medicine plaster of the present invention.

[0033] Treatment

[0034] Apply the Chinese medicine of the present invention on gauze and stick it on the affected area. Change the medicine every other day. One month is one course of treatment. Two courses of treatment are

[0035] The efficacy will be statistically analyzed later. During the clinical trial, the use of other analgesic Chinese and Western medicines or other drugs and therapies is prohibited.

[0036] Efficacy evaluation criteria

[0037] 1. Recovery: Clinical symptoms disappear, the function of the affected part is basically restored, and the patient can move freely without affecting activities and work;

[0038] 2. Effective: Clinical symptoms are significantly improved or improved, or turn from severe to mild, and the function of the affected part is basically restored, without affecting

[0039] It affects work, and only mild symptoms occur when tired;

[0040] 3. Ineffective: Symptoms do not improve or tend to worsen.

[0041] IV. Treatment Outcomes

[0042] Control group: 15 cases were cured, accounting for 42.9%; 14 cases were effective, accounting for 40%; 6 cases were ineffective, accounting for 17.1%; the total effective rate was 82.9%; During the trial, 5 patients had skin discomfort symptoms such as itching and rashes.

[0043] Treatment group: 33 cases were cured, accounting for 94.3%; 2 cases were effective, accounting for 5.7%; 0 cases were ineffective; the total effective rate was 100%, and only 1 patient had skin discomfort symptoms such as itching and rash.

[0044] in conclusion

[0045] Clinical experiments show that the total effective rate of the external Chinese medicine plaster for rheumatoid arthritis is 100%. It is an effective medicine for treating rheumatoid arthritis, has a quick effect, a high cure rate, and has a good clinical promotion significance.

[0046] Clinical Cases

[0047] Case 1: Wang, female, 53 years old, from Zhengzhou, Henan Province, often suffered from wind evil at work and had pain in both knee joints.

[0048] The patient felt cold and was afraid of cold, and the pain was aggravated in rainy weather. The patient was diagnosed with rheumatoid arthritis by the hospital. The pain was sometimes mild and sometimes severe when taking anti-rheumatic drugs, and it could not be cured. After using the Chinese medicine paste of the present invention for a course of treatment, the condition improved. After using it for 2 courses of treatment, the swelling and pain in the joints disappeared and the activity was normal. Follow-up showed no recurrence.

[0049] Case 2: Zhang, female, from Pingdingshan, Henan Province, 41 years old, suffered from rheumatoid arthritis for more than 2 years, with swelling of knee joints, pain when bending joints, and difficulty in going up and down stairs. After using the Chinese medicine plaster of the present invention for 1 course of treatment, the symptoms improved, and after using 2 courses of treatment, the swelling and pain in the joints disappeared, and the activities were normal. Follow-up, no recurrence.

[0050] Case 3: Wang XX, male, 60 years old, first visit, rheumatoid arthritis for more than 7 years, limbs and finger joints affected pain, light during the day and heavy at night, toes swollen and painful, long-term recurrence. This time, the left knee and right wrist joint swelling and deformation are more obvious, limited activity, pale tongue, thin pulse, this belongs to rheumatism phlegm and blood stasis blocking the meridians, long and not. Use the plaster implemented by the present invention, apply the affected part for 1 course of treatment, the pain is significantly alleviated, and continue to apply 2 courses of treatment, without obvious pain, only on rainy days or tiredness, there is a sore feeling, follow-up continued use, no pain, toe swelling is eliminated, deformed joints are stable and have no development.

Claims

1. A traditional plaster containing Xanthoceras sorbifolia ingredients, characterized in that: The plaster is prepared from the following raw materials in parts by weight: 200-1000 parts of Xanthoceras sorbifolia oil, 10-60 parts of Xanthoceras sorbifolia wood, 10-30 parts of Radix Polygoni Multiflori, 5-15 parts of vinegar-cured Cyperus rotundus, 5-20 parts of Angelica dahurica, 1-3 parts of processed Aconiti Kusnezoffii, 1-3 parts of processed Aconiti Kusnezoffii, 1-3 parts of Trichosanthes kirilowii, 5-20 parts of salt Psoralea corylifolia, 10-30 parts of Rhubarb, 5-20 parts of vinegar-curcuma, 5-20 parts of vinegar-curcuma, 1-5 parts of Sanguisorba officinalis, and 1-5 parts of Borneolum.

2. A method for preparing the traditional ointment as claimed in claim 1, characterized in that : Prepare according to the following steps: (1) Select high-quality Xanthoceras sorbifolia fruits and fruit trees. (2) The Xanthoceras sorbifolia fruit is cold pressed to extract pure Xanthoceras sorbifolia oil; the Xanthoceras sorbifolia fruit wood (branches) is cut into several small sections. (3) Boil the squeezed Xanthoceras sorbifolia oil and the cut Xanthoceras sorbifolia wood in corresponding proportions for 30 minutes until the mixture turns brown, then remove and set aside. (4) Grind Radix Polygoni Multiflori, vinegar-cured Cyperus rotundus, Angelica dahurica, processed Chuanwu, processed Caowu, iron mallet, salted Psoralea corylifolia, rhubarb, vinegar-cured frankincense, vinegar-cured myrrh, Ligusticum wallichii, vinegar-curcuma, Sanguisorba officinalis, and borneol into fine powder, and mix them evenly into fine medicinal powder. (5) stirring and boiling the fine powder in step (4) and the mixture in step (3); when the oil temperature rises to 300° C., stopping heating, cooling, filtering, and boiling the filtered mixture for a second time over a low fire until it drips into beads, that is, a drop of plaster drips into cold water and can quickly solidify in the water and form round, non-spreading, and elastic beads, and then stopping heating; (6) Stir-fry the auxiliary material Guangdan until dry, sieve it, add the sieved Guangdan to the medicinal oil, add the material for 5-10 minutes, and then stir at a speed of 200-400 r / min. Stop stirring when the medicinal oil changes from yellowish brown to dark brown, so that the thick paste is formed; (7) Soak the thick paste in cold water for 3-7 days to obtain a detoxified ointment. (8) Put the mixed ointment into a container and seal it for storage.

3. An external application patch comprising the traditional ointment as claimed in claim 1.