Absorption process of double-base absorption medicine

Abstract

The invention discloses an absorption process of a double-base absorption drug, and relates to the technical field of absorption of the double-base absorption drug, and the absorption process comprises the following steps: absorbing nitrocotton and nitroglycerin in water to form a blank absorption drug; mixing the blank absorption medicine, sampling and analyzing after uniformly mixing, and carrying out ingredient calculation according to an analysis result; grinding the centralite into non-blocky particles, and manually mixing the non-blocky particles with the blank absorption medicine; melting vaseline, uniformly spraying the molten vaseline on the absorption medicine mixed with the centralite, and twisting and mixing; uniformly mixing a catalyst and a stabilizer, and then mixing with the mixed absorption medicine; uniformly spraying the plasticizer on the mixed absorption medicine, and twisting and mixing; and carrying out heat preservation on the rubbed and mixed absorption medicine. The loss of the plasticizer can be reduced, and the uniformity of the absorbed medicine is improved.

Description

Technical Field

[0001] The invention relates to the technical field of absorption of double-base absorption medicines, in particular to an absorption process of double-base absorption medicines. Background Art

[0002] The absorption of double-base absorbent is to prepare nitrocellulose in water into a suspension of a certain concentration. Under efficient stirring, the solvent and other components enter or adhere to the nitrocellulose by infiltration, adsorption, diffusion or partial dissolution. In the currently used intermittent absorption method, the plasticizer cannot enter or adhere to the nitrocellulose completely. There is a certain loss in the absorption process, and the uneven dispersion forms "gels", which affects the uniformity of the absorbent. Based on this, an absorption process for double-base absorbent is designed, which adopts dry mixing and rubbing mixing for absorption, reduces the loss of plasticizer and improves the uniformity of the absorbent. Summary of the invention

[0003] The purpose of the present invention is to overcome the shortcomings of the prior art and provide an absorption process for a double-base absorbent. In the prior art, the absorption process is carried out in water, but this will result in the plasticizer being unable to be completely absorbed or attached to the nitrocellulose, resulting in loss, and the absorbent is unevenly dispersed to form "gels", affecting the uniformity of the absorbent. The present invention does not carry out the process in water, that is, it adopts dry mixing and rubbing to carry out absorption, thereby reducing the loss of plasticizer and improving the uniformity of the absorbent.

[0004] The object of the present invention is achieved through the following technical scheme: an absorption process of a double-base absorption drug, the process comprising the following steps:

[0005] S1. Absorb nitrocellulose and nitroglycerin in water as blank absorption medicine.

[0006] S2. Mix the blank absorption medicine, take samples for analysis after mixing evenly, calculate the ingredients according to the analysis results, and weigh each ingredient according to the calculated results.

[0007] S3. Grind the weighed neutralizing agent into lumps-free particles, and then mix it with the blank absorption drug manually.

[0008] S4. Melt the weighed vaseline, and spray the melted vaseline evenly on the absorbent mixed with the neutralizer, and rub to mix.

[0009] S5. After the weighed catalyst and stabilizer are evenly mixed, they are mixed with the mixed absorption drug in step S4. The catalyst is used to accelerate the chemical reaction rate, and the stabilizer is used to increase the stability of the solution, colloid, solid, and mixture, which can slow down the reaction, maintain chemical balance, reduce surface tension, prevent photothermal decomposition or oxidative decomposition, etc.

[0010] S6, the weighed plasticizer is evenly sprayed on the mixed absorption medicine in step S5, and kneaded and mixed. The absorption is carried out by dry mixing and kneading, which reduces the loss of plasticizer and improves the uniformity of the absorption medicine. The main function of the plasticizer is to weaken the secondary bond between polymer molecules, that is, the van der Waals force, thereby increasing the mobility of the polymer molecular chain and reducing the crystallinity of the polymer molecular chain, that is, increasing the plasticity of the polymer, which is manifested as the hardness, modulus, softening temperature and brittle temperature of the polymer decreasing, while the elongation, flexibility and flexibility are improved.

[0011] S7, keeping the mixed absorbent warm.

[0012] Furthermore, in the step S1, nitrocellulose and nitroglycerin are absorbed in water at a ratio of 75:25 to form a blank absorption drug.

[0013] Furthermore, in step S2, the ingredients include a neutralizer, vaseline, a catalyst, a stabilizer and a plasticizer.

[0014] Furthermore, the neutralizing agent is a No. 2 neutralizing agent or diphenylamine, and the No. 2 neutralizing agent is dimethyl diphenyl urea.

[0015] Furthermore, in step S7, the heat preservation is maintained at a constant temperature for one hour.

[0016] Furthermore, the insulation temperature is 60°C to 75°C.

[0017] The beneficial effects of the present invention are:

[0018] In the prior art, the absorption process is carried out in water, but this will result in the plasticizer being unable to be completely absorbed or attached to the nitrocellulose, resulting in loss, and the absorption drug being unevenly dispersed to form "gels", affecting the uniformity of the absorption drug. The present invention does not carry out the process in water, that is, the absorption is carried out by dry mixing and rubbing, which reduces the loss of plasticizer and improves the uniformity of the absorption drug. DETAILED DESCRIPTION

[0019] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be clearly and completely described in combination with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. The components of the embodiments of the present invention generally described and shown herein can be arranged and designed in various different configurations. Therefore, the detailed description of the embodiments of the present invention provided below is not intended to limit the scope of the claimed invention, but merely represents the selected embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in the field without making creative work belong to the scope of protection of the present invention.

[0020] The present invention will be further described below in conjunction with specific embodiments.

[0021] In one embodiment of the present application:

[0022] An absorption process for a double-base absorption drug, the process comprising the following steps:

[0023] S1. Absorb nitrocellulose and nitroglycerin in water at a ratio of 75:25 as blank absorption drug.

[0024] S2. Mix the blank absorption medicine manually, take samples for analysis after mixing evenly, calculate the ingredients based on the analysis results, and weigh each ingredient according to the calculated results. The ingredients include neutralizer, vaseline, catalyst, stabilizer and plasticizer.

[0025] S3. Grind the weighed neutralizer into lumpy particles, and then mix it with the blank absorbent manually. The neutralizer is neutralizer No. 2 or diphenylamine. Neutralizer No. 2 is dimethyl diphenyl urea, which can also be used as a stabilizer.

[0026] S4. Melt the weighed vaseline, and spray the melted vaseline evenly on the absorbent mixed with the neutralizer, and mix it manually.

[0027] S5. After the weighed catalyst and stabilizer are evenly mixed, they are artificially mixed with the mixed absorption drug in step S4. The catalyst is used to accelerate the chemical reaction rate, and the stabilizer is used to increase the stability of the solution, colloid, solid, and mixture, which can slow down the reaction, maintain chemical balance, reduce surface tension, prevent photothermal decomposition or oxidative decomposition, etc.

[0028] S6, the weighed plasticizer is evenly sprayed on the mixed absorption medicine in step S5, and the mixture is mixed manually, and the absorption is carried out by dry mixing and mixing, which reduces the loss of plasticizer and improves the uniformity of the absorption medicine. Steps S3-S6 are all carried out under natural temperature conditions. The main function of the plasticizer is to weaken the secondary bonds between polymer molecules, i.e., van der Waals forces, thereby increasing the mobility of the polymer molecular chains, reducing the crystallinity of the polymer molecular chains, i.e., increasing the plasticity of the polymer, which is manifested as the hardness, modulus, softening temperature and brittle temperature of the polymer decreasing, while the elongation, flexibility and toughness are improved.

[0029] S7. Keep the mixed absorbent warm for one hour after reaching the specified temperature, and the warming temperature is between 60℃ and 75℃.

[0030] The above is only an embodiment of the present invention. It should be understood that the present invention is not limited to the form disclosed herein, and should not be regarded as excluding other embodiments, but can be used in various other combinations, modifications and environments, and can be modified within the scope of the concept described herein through the above teachings or the technology or knowledge of the relevant field. The changes and modifications made by those skilled in the art shall not deviate from the spirit and scope of the present invention, and shall be within the scope of protection of the claims attached to the present invention.

Claims

1. An absorption process for a double-base absorbent, characterized in that: The following steps are involved: S1. Absorb nitrocellulose and nitroglycerin in water as blank absorption medicine; S2. Mix the blank absorption medicine, take samples for analysis after mixing evenly, and calculate the ingredients according to the analysis results; S3, grinding the intermediate agent into granules without lumps, and then manually mixing it with the blank absorption drug; S4, melting vaseline, and evenly spraying the melted vaseline on the absorbent mixed with the neutralizing agent, and rubbing and mixing; S5, after the catalyst and the stabilizer are evenly mixed, they are mixed with the mixed absorption drug in step S4; S6, spraying the plasticizer evenly on the mixed absorbent in step S5, and kneading and mixing; S7, keeping the mixed absorbent warm.

2. The absorption process of a double-base absorption drug according to claim 1, characterized in that: In the step S1, nitrocellulose and nitroglycerin are absorbed in water at a ratio of 75:25 to form a blank absorption drug.

3. The absorption process of a double-base absorbent according to claim 1, characterized in that: In the step S2, the ingredients include a neutralizer, vaseline, a catalyst, a stabilizer and a plasticizer.

4. The absorption process of a double-base absorbent according to claim 1, characterized in that: The intermediate fixative is intermediate fixative No.

2.

5. The absorption process of a double-base absorption drug according to claim 1, characterized in that: The neutralizing agent is diphenylamine.

6. The absorption process of a double-base absorption drug according to claim 1, characterized in that: In step S7, the heat preservation is performed at a constant temperature for one hour.

7. The absorption process of a double-base absorbent according to claim 1 or 6, characterized in that: The insulation temperature is 60°C to 75°C.