Synthesis system

Abstract

This synthesis system is provided with a first flow path unit, a second flow path unit, a third flow path unit, and a switching unit. The first flow path portion is connected to a first container capable of accommodating a liquid raw material. The second flow path portion is connected to a second container capable of accommodating a liquid raw material. The third flow path portion connects the first container and the second container. A synthesis reaction device for generating a reaction product from the liquid raw material is connected to the third flow path part. The switching unit is capable of switching between a flow path state in which the gas supplied by the gas supply unit is guided to the first flow path unit and a flow path state in which the gas supplied by the gas supply unit is guided to the second flow path unit.

Description

Technical Field

[0001] The present invention relates to a synthesis system. Background Art

[0002] By synthesis such as polymerization, a reaction product such as a medicine, food or chemical substance is generated from a raw material (see, for example, Japanese Patent No. 6733985). In recent years, flow synthesis has been developed as a synthesis method for generating a reaction product from a raw material. Summary of the invention

[0003] In a synthesis system for flow synthesis, it is possible to configure a photopolymerization reaction device between two containers. The operator connects an inert gas supply device to one of the containers. In this case, an inert gas is supplied to one of the containers, and the raw materials contained in the container are pressure-transferred to the other container through the photopolymerization reaction device. In the photopolymerization reaction device, by irradiating the raw materials with light for a certain period of time, a reaction product is generated from a part of the raw materials. Therefore, a mixture of the reaction product and the unreacted raw materials is contained in the other container.

[0004] After that, the operator connects the inert gas supply device to another container. In this case, the inert gas is supplied to the other container, and the raw materials contained in the container are pressure-fed to one of the containers through the photopolymerization reaction device. Thus, a mixture of the reaction product and the remaining unreacted raw materials is contained in one of the containers. By repeating the above operation, a sufficient amount of reaction product is generated.

[0005] However, in the process of generating the reaction product, since the raw material needs to be irradiated with light several dozen times, the burden on the operator is large. Therefore, it is desired to develop a synthesis system that can reduce the burden on the operator.

[0006] An object of the present invention is to provide a synthesis system capable of reducing the burden on operators.

[0007] One embodiment of the present invention relates to a synthesis system, comprising: a first flow path portion connected to a first container capable of accommodating a liquid raw material; a second flow path portion connected to a second container capable of accommodating a liquid raw material; a third flow path portion connecting the first container and the second container and connected to a synthesis reaction device that generates a reaction product from the liquid raw material; and a switching portion capable of switching between a flow path state in which a gas supplied by a gas supply portion is directed to the first flow path portion and a flow path state in which a gas supplied by the gas supply portion is directed to the second flow path portion.

[0008] According to the present invention, the burden on operators in fluid synthesis can be reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0009] Figure 1It is a diagram showing the configuration of a synthesis system according to one embodiment of the present invention.

[0010] Figure 2 This is a diagram for explaining the operation of the synthesis system.

[0011] Figure 3 This is a diagram for explaining the operation of the synthesis system.

[0012] Figure 4 This is a diagram for explaining the operation of the synthesis system.

[0013] Figure 5 This is a diagram for explaining the operation of the synthesis system.

[0014] Figure 6 It is a diagram showing the structure of the control unit.

[0015] Figure 7 It means by Figure 6 A flowchart of an example of an algorithm for synthesis processing executed by a control unit.

[0016] Figure 8 It is a diagram showing the configuration of a synthesis system according to a first modification.

[0017] Fig. 9 It is a diagram showing the structure of a synthesis system according to a second modification.

[0018] Fig.10 It is a diagram showing the structure of a synthesis system according to a third modification. DETAILED DESCRIPTION

[0019] (1) Structure of the synthesis system

[0020] Hereinafter, a synthesis system according to an embodiment of the present invention will be described in detail with reference to the drawings. Figure 1 1 is a diagram showing the structure of a synthesis system according to one embodiment of the present invention. Figure 1 As shown, the synthesis system 100 is connected to the analysis device 200. The analysis device 200 includes a fractionation device. In this embodiment, the analysis device 200 is a liquid chromatograph, but it can also be other analysis devices.

[0021] The synthesis system 100 includes a container 10, a container 20, a gas supply unit 30, a switching unit 40, a switching unit 50, a synthesis reaction device 60, a sample supply unit 70, and a control unit 80. In addition, the synthesis system 100 includes a flow path unit 101 to a flow path unit 104. The flow path unit 101 to the flow path unit 103 are examples of the first flow path unit to the third flow path unit, respectively. Each of the flow path units 101 to 104 may also be composed of one or more pipes.

[0022] The container 10 and the container 20 are examples of the first container and the second container, respectively. Each of the container 10 and the container 20 is, for example, a flask, and can contain a liquid raw material. In this embodiment, the liquid raw material is a monomer. The gas supply unit 30 supplies nitrogen. The gas supply unit 30 can supply other inert gases, or can also supply gases such as clean air.

[0023] The switching unit 40 is, for example, a multi-directional switching valve, and has six ports 41 to 46. The switching unit 40 is an example of a switching unit, and can be switched between a first flow path state and a second flow path state. In the first flow path state, ports 41 and 42 are connected, ports 43 and 44 are connected, and ports 45 and 46 are connected. In the second flow path state, ports 42 and 43 are connected, ports 44 and 45 are connected, and ports 46 and 41 are connected.

[0024] The port 41 is connected to the gas supply unit 30. The port 42 is connected to the container 10 via the flow path unit 101. The ports 43 and 45 are open to the atmosphere. The port 46 is connected to the container 20 via the flow path unit 102. According to the connection, in the first flow path state, the gas supplied by the gas supply unit 30 is guided to the container 10 via the flow path unit 101. In the second flow path state, the gas supplied by the gas supply unit 30 is guided to the container 20 via the flow path unit 102.

[0025] The container 10 and the container 20 are connected through the flow path portion 103. The flow path portion 103 is provided with a switching portion 50 and a synthetic reaction device 60. The switching portion 50 is connected to the analysis device 200. The switching portion 50 is a multi-directional switching valve similar to the switching portion 40, and can be switched to a third flow path state and a fourth flow path state. In the third flow path state, the liquid is guided between the container 10 and the container 20. In the fourth flow path state, the liquid flowing through the flow path portion 103 is guided to the analysis device 200. Here, the liquid includes a liquid raw material or a reaction product described later.

[0026] The liquid raw material flowing through the flow path portion 103 is retained while passing through the synthesis reaction device 60 for a certain period of time. The synthesis reaction device 60 generates a reaction product from the liquid raw material by reacting the liquid raw material passing through itself. In the present embodiment, the synthesis reaction device 60 is a photopolymerization reaction device and includes a light source capable of emitting ultraviolet rays. By irradiating the liquid raw material passing through the synthesis reaction device 60 with ultraviolet rays, a high molecular polymer is generated as a reaction product.

[0027] The sample supply unit 70 includes a plurality of Figure 1In the example of the embodiment of the present invention, there are four bottles 71 to 74, a switching unit 75 and a liquid feeding unit 76. Bottle 71 contains a liquid raw material for replenishment. Bottles 72 to 74 each contain a liquid additive. The switching unit 75 has five ports 75a to 75e, which can be switched to any one of the fifth flow path state to the eighth flow path state. In the fifth flow path state to the eighth flow path state, ports 75a to 75d are connected to port 75e, respectively.

[0028] Ports 75a to 75d are connected to bottles 71 to 74, respectively. Port 75e is connected to a liquid delivery unit 76. According to the connection, in the fifth flow path state, the liquid raw material contained in bottle 71 is guided to the liquid delivery unit 76. In the sixth flow path state to the eighth flow path state, the liquid additive contained in bottle 72 to bottle 74 is guided to the liquid delivery unit 76, respectively.

[0029] The liquid supply unit 76 includes, for example, a pump, and supplies the liquid raw material or liquid additive guided by the switching unit 75 to the container 10 via the flow path unit 104. In this way, the liquid raw material can be replenished to the container 10. Alternatively, the liquid additive can be added to the liquid raw material in the container 10. The liquid supply unit 76 may also be connected to the container 20 via the flow path unit 104. In this case, the liquid supply unit 76 supplies the liquid raw material or liquid additive guided by the switching unit 75 to the container 20 via the flow path unit 104.

[0030] The control unit 80 includes a memory 81 and a central processing unit (CPU) 82. In addition, in the present embodiment, the control unit 80 further includes a timer 83 for measuring the elapsed time. The memory 81 stores a synthesis program for generating a reaction product from a liquid raw material. The CPU 82 controls the operation of the gas supply unit 30, the switching unit 40, the switching unit 50, the synthesis reaction device 60, and the sample supply unit 70 according to the synthesis program stored in the memory 81. The details of the control unit 80 will be described below.

[0031] (2) Operation of the synthesis system

[0032] Figure 2 to Figure 5 1 is a diagram for explaining the operation of the synthesis system 100. In the initial state of the synthesis system 100, it is assumed that the liquid raw material is not contained in the container 10 or the container 20. Therefore, the flow path state of the switching unit 75 of the sample supply unit 70 is switched to the fifth flow path state, and the liquid supply unit 76 is driven. In this case, Figure 2 As shown by the thick solid arrow, the liquid raw material contained in the bottle 71 is pressure-fed to the container 10 via the flow path 104. After a predetermined time has passed, the driving of the liquid feeding unit 76 is stopped. Thus, a certain amount of the liquid raw material is contained in the container 10.

[0033] Next, the flow path state of the switching unit 40 is switched to the first flow path state, and the flow path state of the switching unit 50 is switched to the third flow path state. In this state, the gas supply unit 30 is driven. In this case, the gas supplied by the gas supply unit 30 is guided to the container 10 via the flow path unit 101, thereby Figure 3 As shown by the thick solid arrow, the liquid raw material contained in the container 10 is pressure-fed to the container 20 via the flow path 103. The gas supplied to the container 10 passes through the flow path 103, the container 20, the flow path 102, and the ports 46 and 45 of the switching unit 40 in sequence and is discharged into the atmosphere.

[0034] In the flow path section 103, the liquid raw material passes through the synthesis reaction device 60, whereby a part of the liquid raw material reacts. Thus, a reaction product is generated from a part of the liquid raw material. Therefore, a liquid (hereinafter referred to as liquid raw material) mixed with the unreacted liquid raw material and the reaction product after the reaction is contained in the container 20.

[0035] Thereafter, when the switching condition of the flow path state of the switching unit 40 is satisfied, the flow path state of the switching unit 40 is switched from the first flow path state to the second flow path state. The switching condition of the flow path state of the switching unit 40 is, for example, that the amount of liquid in the container 10 or the container 20 becomes less than a predetermined value. Therefore, when the amount of liquid in the container 10 becomes less than a predetermined value, the flow path state of the switching unit 40 is switched from the first flow path state to the second flow path state.

[0036] The operator may determine the time until the amount of liquid in the container 10 or 20 becomes less than the specified value through experiments or calculations, and set the determined time in the control unit 80. In this case, when the time measured by the timer 83 reaches the set time, it is determined that the amount of liquid in the container 10 or 20 becomes less than the specified value, and the flow path state of the switching unit 40 is switched.

[0037] Alternatively, the switching condition of the flow path state of the switching unit 40 may be that the amount of liquid in the container 10 or 20 becomes greater than a specified value. In this case, when the amount of liquid in the container 20 becomes greater than the specified value, the flow path state of the switching unit 40 is switched from the first flow path state to the second flow path state. In this case, the operator may determine the time until the amount of liquid in the container 10 or 20 becomes greater than the specified value through experiments or calculations, and set the determined time in the control unit 80. In this case, when the time measured by the timer 83 reaches the set time, it is determined that the amount of liquid in the container 10 or 20 becomes greater than the specified value, and the flow path state of the switching unit 40 is switched.

[0038] By switching the flow path state of the switching unit 40 to the second flow path state, the gas supplied by the gas supply unit 30 is guided to the container 20 via the flow path unit 102. In this case, Figure 4 As shown by the thick solid arrow, the liquid raw material contained in the container 20 is pressure-fed to the container 10 via the flow path 103. The gas supplied to the container 20 passes through the flow path 103, the container 10, the flow path 101, and the ports 42 and 43 of the switching unit 40 in sequence and is discharged into the atmosphere.

[0039] In the flow path section 103, the liquid raw material passes through the synthesis reaction device 60, whereby a portion of the unreacted liquid raw material reacts. Thus, a reaction product is further generated from a portion of the unreacted liquid raw material. Therefore, the container 10 contains a liquid mixed with the unreacted liquid raw material and the reaction product that has been reacted.

[0040] Thereafter, when the switching condition of the flow path state of the switching unit 40 is satisfied, the flow path state of the switching unit 40 is switched from the second flow path state to the first flow path state. Figure 3 Action and Figure 4 Each time these actions are repeated, the amount of the reaction product in the liquid raw material contained in the container 10 or the container 20 increases.

[0041] Furthermore, when the liquid raw material contained in the container 10 is reduced, the switching unit 75 may be switched to the fifth flow path state in the sample supply unit 70, and the liquid raw material may be appropriately replenished to the container 10 by driving the liquid supply unit 76. Furthermore, when the reaction of the liquid raw material has proceeded to a certain extent, the switching unit 75 may be switched to any one of the sixth to eighth flow path states, and a predetermined additive may be supplied to the container 10 by driving the liquid supply unit 76. Thus, the reaction can be promoted.

[0042] Thereafter, when the switching condition of the flow path state of the switching unit 50 is satisfied, the flow path state of the switching unit 50 is switched from the third flow path state to the fourth flow path state. In the present embodiment, the switching condition of the flow path state of the switching unit 50 is that the elapsed time measured by the timer 83 reaches the time set in the control unit 80. The operator can determine the time until a sufficient amount of reaction product is generated through experiments or calculations, and set the determined time in the control unit 80. In this case, when a sufficient amount of reaction product is generated, the flow path state of the switching unit 50 is switched from the third flow path state to the fourth flow path state.

[0043] Alternatively, the switching condition of the flow path state of the switching unit 50 may be that the number of switching times of the flow path state of the switching unit 40 reaches the number of times set in the control unit 80. The operator may also determine the number of switching times of the flow path state of the switching unit 40 until a sufficient amount of reaction product is generated through experiments or calculations, and set the determined number of times in the control unit 80. In this case, when a sufficient amount of reaction product is generated, the flow path state of the switching unit 50 is also switched from the third flow path state to the fourth flow path state.

[0044] By switching the flow path state of the switching unit 50 to the fourth flow path state, as shown in FIG. Figure 5 As shown by the arrow of the thick solid line, the liquid raw material contained in the container 20 is pressure-fed to the analysis device 200 via the flow path portion 103. In addition, according to the timing when the flow path state of the switching unit 50 is switched to the fourth flow path state, the liquid raw material contained in the container 10 is pressure-fed to the analysis device 200 via the flow path portion 103. In the analysis device 200, the reaction product generated by the synthesis reaction device 60 is analyzed. In addition, the analyzed reaction product is recovered by a fractionation device not shown.

[0045] (3) Synthesis processing

[0046] Figure 6 It is a diagram showing the structure of the control unit 80. Figure 7 It means by Figure 6 Flowchart of an example of an algorithm for the synthesis process performed by the control unit 80. Figure 6 As shown in FIG. 1 , the control unit 80 includes a sample control unit 84, a gas control unit 85, a switching control unit 86, a switching control unit 87, and a synthesis control unit 88 as functional units. Figure 1 The CPU 82 executes the synthesis program stored in the memory 81 to realize the functional units of the control unit 80. A part or all of the functional units of the control unit 80 may be realized by hardware such as an electronic circuit.

[0047] Below, use Figure 2 to Figure 5 Synthesis system 100, Figure 6 The control unit 80 and Figure 7 First, the sample control unit 84 controls the sample supply unit 70 to replenish the liquid raw material to the container 10 (steps S1 and Figure 2 ) In addition, in the initial state of the synthesis system 100, when the liquid raw material is contained in the container 10, step S1 can also be omitted.

[0048] Next, the gas control unit 85 supplies gas through the gas supply unit 30 (step S2). In addition, the switching control unit 87 switches the flow path state of the switching unit 50 to the third flow path state (step S3). Furthermore, the switching control unit 86 switches the flow path state of the switching unit 40 to the first flow path state (step S4). Any one of steps S2 to S4 may be performed first or simultaneously.

[0049] By executing steps S2 to S4, the liquid raw material contained in the container 10 is pressure-fed to the container 20 via the flow path 103 ( Figure 3Here, the synthesis control unit 88 controls the synthesis reaction device 60 to generate a reaction product from the liquid raw material passing through the synthesis reaction device 60 (step S5).

[0050] Then, the switching control unit 86 determines whether the switching condition of the flow path state of the switching unit 40 is satisfied (step S6). If the switching condition of the flow path state of the switching unit 40 is not satisfied, the switching control unit 86 returns the process to step S5. Steps S5 and S6 are repeated until the switching condition of the flow path state of the switching unit 40 is satisfied.

[0051] When the switching condition of the flow path state of the switching unit 40 is satisfied, the switching control unit 86 switches the flow path state of the switching unit 40 to the second flow path state (step S7). As a result, the liquid raw material contained in the container 20 is pressure-fed from the flow path unit 103 ( Figure 4 Here, the synthesis control unit 88 controls the synthesis reaction device 60 to generate a reaction product from the liquid raw material passing through the synthesis reaction device 60 (step S8).

[0052] Thereafter, the switching control unit 87 determines whether the switching condition of the flow path state of the switching unit 50 is satisfied (step S9). If the switching condition of the flow path state of the switching unit 50 is not satisfied, the liquid raw material pressure-fed from the container 20 is guided to the container 10. In this case, the switching control unit 86 determines whether the switching condition of the flow path state of the switching unit 40 is satisfied (step S10).

[0053] If the switching condition of the flow path state of the switching unit 40 is satisfied, the switching control unit 86 returns the process to step S4. As a result, the liquid raw material is again pressure-fed from the container 10 to the container 20. At this point in time, the sample control unit 84 can control the sample supply unit 70 to replenish the liquid raw material to the container 10, or add a liquid additive to the liquid raw material in the container 10. On the other hand, if the switching condition of the flow path state of the switching unit 40 is not satisfied, the switching control unit 86 returns the process to step S8.

[0054] When the switching condition of the flow path state of the switching unit 50 is satisfied in step S9, the switching control unit 87 switches the flow path state of the switching unit 50 to the fourth flow path state (step S11). Thus, the reaction products generated in steps S5 and S8 are supplied to the analysis device 200 ( Figure 5 ). In the analysis device 200, the supplied reaction product is analyzed and separated. Thereafter, the process returns to step S1. Thus, the same process is repeated. The synthesis process may also end after the execution of step S11.

[0055] (4) Modification

[0056] In the synthesis system 100 , the liquid raw material may be adjusted to a temperature suitable for the reaction. Figure 8 1 is a diagram showing the structure of a synthesis system 100 according to a first modification. Figure 8 As shown, the synthesis system 100 of this example includes one or more temperature adjustment units 90. Each temperature adjustment unit 90 may be, for example, a heater or a Peltier element.

[0057] exist Figure 8 In the example of FIG. 1 , the temperature regulating unit 90 is installed in the container 10, the container 20, and the flow path unit 103. Thus, the liquid raw material contained in the container 10, the liquid raw material contained in the container 20, and the liquid raw material flowing through the flow path unit 103 are temperature-regulated by the temperature regulating unit 90. The temperature regulating unit 90 need not be installed in all of the container 10, the container 20, and the flow path unit 103, but may be installed in any one of the container 10, the container 20, and the flow path unit 103. In addition, when the temperature regulating unit 90 is installed in the flow path unit 103, the reaction can also be promoted.

[0058] In addition, in the present embodiment, the flow path state of the switching unit 40 is switched based on the elapsed time measured by the timer 83 , but the embodiment is not limited to this. Fig. 9 2 is a diagram showing the structure of a synthesis system 100 according to a second variation. Fig. 9 As shown, the synthesis system 100 of this example further includes the liquid level sensor 11 and the liquid level sensor 21. In addition, in the second modification example or the third modification example described later, the control unit 80 does not include the timer 83.

[0059] The liquid level sensors 11 and 21 detect the liquid levels of the liquid raw materials respectively contained in the containers 10 and 20. The liquid level sensors 11 and 21 may be, for example, cameras that capture images of the liquid raw materials respectively contained in the containers 10 and 20. In this case, the liquid levels of the liquid raw materials respectively contained in the containers 10 and 20 are detected based on the images of the liquid raw materials.

[0060] For example, the operator may set the height of the liquid level when the amount of liquid in the container 10 or 20 becomes less than a specified value in the control unit 80. Alternatively, the height of the liquid level when the amount of liquid in the container 10 or 20 becomes less than a specified value may be preset to a specified value. In these cases, when the height of the liquid level detected by the liquid level sensor 11 or 21 reaches the set height, it is determined that the amount of liquid in the container 10 or 20 becomes less than the specified value, and the flow path state of the switching unit 40 is switched.

[0061] On the other hand, the operator may set the height of the liquid level when the amount of liquid in the container 10 or 20 becomes greater than a predetermined value in the control unit 80. Alternatively, the height of the liquid level when the amount of liquid in the container 10 or 20 becomes greater than a predetermined value may be preset to a predetermined value. In these cases, when the height of the liquid level detected by the liquid level sensor 11 or 21 reaches the set height, it is determined that the amount of liquid in the container 10 or 20 becomes greater than the predetermined value, and the flow path state of the switching unit 40 is switched.

[0062] Fig.10 is a diagram showing the structure of a synthesis system 100 according to a third variation. Fig.10 As shown, the synthesis system 100 of this example further includes a weight sensor 12 and a weight sensor 22. The weight sensor 12 and the weight sensor 22 detect the weight of the liquid raw material contained in the container 10 and the container 20, respectively.

[0063] For example, the operator may set the weight of the liquid raw material when the amount of liquid in the container 10 or 20 becomes less than a specified value in the control unit 80. Alternatively, the weight of the liquid raw material when the amount of liquid in the container 10 or 20 becomes less than a specified value may be preset to a specified value. In these cases, when the weight detected by the weight sensor 12 or the weight sensor 22 reaches the set weight, it is determined that the amount of liquid in the container 10 or 20 becomes less than the specified value, and the flow path state of the switching unit 40 is switched.

[0064] On the other hand, the operator may set the weight of the liquid raw material when the amount of liquid in the container 10 or 20 becomes greater than a predetermined value in the control unit 80. Alternatively, the weight of the liquid raw material when the amount of liquid in the container 10 or 20 becomes greater than a predetermined value may be set in advance to a predetermined value. In these cases, when the weight detected by the weight sensor 12 or the weight sensor 22 reaches the set weight, it is determined that the amount of liquid in the container 10 or 20 becomes greater than the predetermined value, and the flow path state of the switching unit 40 is switched.

[0065] (5) Effect

[0066] In the synthesis system 100 of the present embodiment, the gas is supplied from the gas supply unit 30 to the container 10 via the flow path unit 101, and the liquid raw material contained in the container 10 is transferred to the container 20 via the flow path unit 103 and the synthesis reaction device 60. In addition, the gas is supplied from the gas supply unit 30 to the container 20 via the flow path unit 102, and the liquid raw material contained in the container 20 is transferred to the container 10 via the flow path unit 103 and the synthesis reaction device 60. By repeating the above operations, a sufficient amount of reaction product is generated.

[0067] Here, by switching the flow path state of the switching unit 40, the gas supply to the container 10 and the gas supply to the container 20 can be easily performed. Therefore, the operator does not need to reconnect the gas supply unit 30 to the container 10 or the container 20 each time. This can reduce the burden on the operator.

[0068] In addition, the synthesis system 100 includes a control unit 80, and the control unit 80 switches the flow path state of the switching unit 40 when a predetermined switching condition is satisfied. Therefore, the burden on the operator can be further reduced. The switching condition may be that the amount of liquid in the container 10 or the container 20 becomes less than a predetermined value, or may be that the amount of liquid in the container 10 or the container 20 becomes more than a predetermined value. In this case, the flow path state of the switching unit 40 can be easily switched at an appropriate timing.

[0069] (6) Other Implementation Methods

[0070] (a) In the above embodiment, the control unit 80 switches the flow path state of the switching unit 40 and the switching unit 50, but the embodiment is not limited to this. The operator can also manually switch the flow path state of the switching unit 40 and the switching unit 50. In this case, the operator does not need to reconnect the gas supply unit 30 to the container 10 or the container 20 each time. Thus, the burden on the operator can be reduced. In this structure, the control unit 80 does not include the switching control unit 86 and the switching control unit 87.

[0071] (b) In the above embodiment, the synthesis reaction device 60 is a photopolymerization reaction device, but the embodiment is not limited thereto. The synthesis reaction device 60 may also be a reactor such as a plug flow reactor. In this case, the synthesis reaction device 60 generates a reaction product from the liquid raw material by adjusting the temperature and pressure of the liquid raw material passing through itself.

[0072] (c) In the above embodiment, the sample supply unit 70 performs replenishment of the liquid raw material and addition of the liquid additive, but the embodiment is not limited to this. The sample supply unit 70 may also perform replenishment of the liquid raw material and not perform addition of the liquid additive. In this case, the sample supply unit 70 does not include the bottles 72 to 74 and the switching unit 75.

[0073] In addition, the sample supply unit 70 may add a liquid additive without replenishing a liquid raw material. In this case, the sample supply unit 70 does not include the bottle 71. In addition, only one of the bottles 72 to 74 may be provided in the sample supply unit 70. In this case, the sample supply unit 70 does not include the switching unit 75.

[0074] (d) In the above embodiment, the generated reaction product is analyzed, but the embodiment is not limited thereto. The generated reaction product may not be analyzed. In this case, the switching unit 50 may not be connected to the analysis device 200, and may be connected to a separation device for recovering the generated reaction product. In addition, after the reaction product is generated, when the container 10 or the container 20 containing the reaction product is recovered, the switching unit 50 may not be provided in the flow path unit 103.

[0075] (7) Morphology

[0076] Those skilled in the art will appreciate that the multiple exemplary embodiments are specific examples of the following forms.

[0077] (Item 1) A synthetic system of one form may also include:

[0078] The first flow path is connected to a first container capable of containing a liquid raw material;

[0079] The second flow path is connected to a second container capable of containing the liquid raw material;

[0080] a third flow path portion, connecting the first container and the second container, and connected to a synthesis reaction device for generating a reaction product from a liquid raw material; and

[0081] The switching unit is capable of switching between a flow path state in which the gas supplied by the gas supply unit is guided to the first flow path unit and a flow path state in which the gas supplied by the gas supply unit is guided to the second flow path unit.

[0082] In the synthesis system, the gas is supplied from the gas supply unit to the first container via the first flow path unit, and the liquid raw material contained in the first container is transported to the second container via the third flow path unit and the synthesis reaction device. In addition, the gas is supplied from the gas supply unit to the second container via the second flow path unit, and the liquid raw material contained in the second container is transported to the first container via the third flow path unit and the synthesis reaction device. By repeating the above operation, a sufficient amount of reaction product is generated.

[0083] Here, by switching the flow path state of the switching unit, the gas supply to the first container and the gas supply to the second container can be easily performed. Therefore, the operator does not need to reconnect the gas supply unit to the first container or the second container each time. Thus, the burden on the operator can be reduced.

[0084] (Second Item) The synthesis system according to the first Item may further include a control unit,

[0085] The control unit switches the flow path state of the switching unit when a predetermined switching condition is satisfied.

[0086] In this case, the user of the synthesis system does not need to switch the flow path state of the switching unit. This can further reduce the burden on the user.

[0087] (Item 3) The synthesis system according to Item 2, wherein

[0088] The switching condition may be that the amount of liquid in the first container or the second container becomes equal to or less than a predetermined value.

[0089] In this case, the flow path state of the switching portion can be easily switched at an appropriate timing.

[0090] (Item 4) The synthesis system according to Item 2, wherein:

[0091] The switching condition may be that the amount of liquid in the first container or the second container becomes equal to or larger than a predetermined value.

[0092] In this case, the flow path state of the switching portion can be easily switched at an appropriate timing.

Claims

1. A synthesis system comprising: The first flow path is connected to a first container capable of containing a liquid raw material; The second flow path is connected to a second container capable of containing the liquid raw material; a third flow path portion, connecting the first container and the second container, and connected to a synthesis reaction device for generating a reaction product from a liquid raw material; and The switching unit is capable of switching between a flow path state in which the gas supplied by the gas supply unit is guided to the first flow path unit and a flow path state in which the gas supplied by the gas supply unit is guided to the second flow path unit. 2 . The synthesis system according to claim 1 , further comprising a control unit configured to switch a flow path state of the switch unit when a predetermined switching condition is satisfied.

3. The synthesis system according to claim 2, wherein: The switching condition is that the amount of liquid in the first container or the second container becomes equal to or less than a predetermined value.

4. The synthesis system according to claim 2, wherein: The switching condition is that the amount of liquid in the first container or the second container becomes equal to or greater than a predetermined value.

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