Operating state reagent loading method
By setting up a controller and a detector in the biochemical instrument, and automatically controlling the loader to add reagents to the reagent disk, the complex and unstable reagent supplementation process in the prior art is solved, and a high degree of automation and safe reagent loading method is achieved.
Patent Information
- Application Number
- CN202411825455.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-12
- Publication Date
- 2025-03-07
AI Technical Summary
In the prior art, the reagent supplementation process in biochemical instruments has problems such as complex operation, huge workload and poor safety. Especially when the sample size is large, the reagent disc rotates unstable, which affects the supplement effect.
By setting up a controller between the reagent disk and the loader, the detector uses the detector to detect that the reagent is insufficient, the controller sends a signal to automatically rotate the loader and add an appropriate amount of reagent to achieve automated reagent loading.
It improves the degree of automation of reagent supplements, reduces operational complexity and workload, ensures stable operation and safety of reagent disks, and simplifies the operation process.
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of testing operations and relates to a reagent loading method in a running state. Background Art
[0002] At present, with the widespread application of biochemical analyzers and the continuous increase in sample volume, the requirements for biochemical analyzers to be high-speed, simple to use and automated are becoming increasingly higher, so as to reduce the workload of operators and improve work efficiency.
[0003] During the use of the biochemical analyzer, as the sample volume continues to increase, reagents need to be replenished in a timely manner to meet the test needs.
[0004] To solve the above problems, there are usually two solutions: First, reagents are replenished before and after the test, but not during the test.
[0005] This ensures that the test process is not affected and that the appropriate amount of reagent is always available during the test.
[0006] Second, replenish reagents during the test.
[0007] It can be seen that the first method is complicated and tedious to operate, and the workload is huge.
[0008] The second method is less safe and the replenishment is unstable. That is, the reagent tray rotating during the reagent replenishment process may touch the operator, and whether the reagent tray during the rotation process can stably replenish the appropriate amount of reagent depends entirely on the operator's experience, and its stability is also relatively poor. Summary of the invention
[0009] The object of the present invention is to provide a reagent loading method in an operating state with high automation and simple testing in view of the above problems existing in the prior art.
[0010] The purpose of the present invention can be achieved by the following technical solutions: A reagent loading method in a running state, wherein a reagent disk and a loader having a reagent needle are arranged adjacent to each other, characterized in that the reagent disk is in the shape of a disk and has a plurality of storage portions for storing reagent bottles or reagent tubes along its circumference, and a controller capable of receiving and sending signals is provided between the reagent disk and the loader, and the loading method comprises the following steps: Detection: Each storage part of the reagent disk has a corresponding detector, which can detect whether the corresponding storage part has an appropriate amount of reagent. When the detector detects that the amount of reagent in the corresponding storage part is less than the set amount, the controller sends a corresponding coded signal to the loader; Execute adding: after the loader with the reagent needle receives the above number signal, the loader rotates relative to the reagent disk until the reagent needle on it is located directly above the corresponding storage part, and the reagent needle delivers the corresponding amount of reagent to the storage part; Reset: After the loader completes the adding operation, the loader resets to the initial position.
[0011] In the reagent loading method in the above-mentioned operating state, each storage unit has a corresponding digital identification A, the missing reagent signal at the storage unit is B, and the above-mentioned number signal is A+B.
[0012] In the above-mentioned reagent loading method in the running state, the detector is a CCD camera.
[0013] In the above-mentioned reagent loading method in the operating state, the detector is sensor one.
[0014] In the reagent loading method in the above-mentioned operating state, the loader includes a turntable and a reagent needle fixedly connected to the turntable, a connecting shaft is fixedly connected to the center of the reagent disk, the turntable is sleeved on the connecting shaft and the turntable can intermittently rotate relative to the connecting shaft.
[0015] In the reagent loading method in the above-mentioned operating state, a servo motor is fixedly connected to the connecting shaft, and the servo motor controls the intermittent rotation of the turntable.
[0016] In the reagent loading method in the above-mentioned operating state, an end cover is buckled and connected to the reagent disk, and the end cover is opened before executing step B.
[0017] In the reagent loading method in the above-mentioned operating state, the end cover is hinged at the edge of the reagent disk, and a cylinder is provided between the reagent disk and the end cover, and the piston rod of the cylinder can drive the end cover to swing relative to the reagent disk.
[0018] In the reagent loading method in the above-mentioned operating state, the connecting shaft is also provided with a second sensor, and the second sensor is used to detect whether the end cover is opened.
[0019] In the reagent loading method in the above-mentioned operating state, the above-mentioned sensor 1 and sensor 2 are both connected to the controller, and the controller can control the turntable or the end cover to perform corresponding actions after receiving the above-mentioned signal.
[0020] Compared with the prior art, the reagent loading method in the operating state controls the loader to rotate to a set position and add an appropriate amount of reagent through a controller. Therefore, the reagent disk that does not need to be operated during the adding process stops rotating, and the degree of automation is relatively high.
[0021] At the same time, adding an appropriate amount of reagent into the reagent needle in advance can ensure the stable operation of the reagent disk. The operation is relatively simple and has high practical value. DETAILED DESCRIPTION
[0022] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0023] It should be noted that when a component is referred to as being "mounted on" another component, it may be directly mounted on the other component or there may be a central component. When a component is considered to be "set on" another component, it may be directly set on the other component or there may be a central component at the same time. When a component is considered to be "fixed to" another component, it may be directly fixed on the other component or there may be a central component at the same time.
[0024] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "or / and" used herein includes any and all combinations of one or more related listed items.
[0025] The reagent disk and the loader with a reagent needle are arranged adjacent to each other. The reagent disk is disc-shaped and has a plurality of storage parts for storing reagent bottles or reagent tubes along its circumference. A controller capable of receiving and sending signals is provided between the reagent disk and the loader.
[0026] In this embodiment, each storage part has a corresponding digital identification A, the missing reagent signal at the storage part is B, and the above numbered signal is A+B.
[0027] The reagent loading method of this operating state includes the following steps: Detection: Each storage part of the reagent disk has a corresponding detector, which can detect whether the corresponding storage part has an appropriate amount of reagent. When the detector detects that the amount of reagent in the corresponding storage part is less than the set amount, the controller sends a corresponding coded signal to the loader; In this embodiment, the detector is a CCD camera. According to actual conditions, it is also feasible that the detector is a sensor.
[0028] B. Execute addition: After the loader with the reagent needle receives the above-mentioned number signal, the loader rotates relative to the reagent disk until the reagent needle on it is located directly above the corresponding storage part, and the reagent needle delivers the corresponding amount of reagent to the storage part; C. Reset: After the loader completes the adding operation, the loader resets to the initial position.
[0029] The loader comprises a turntable and a reagent needle fixedly connected to the turntable. A connecting shaft is fixedly connected to the center of the reagent disk. The turntable is sleeved on the connecting shaft and can rotate intermittently relative to the connecting shaft.
[0030] A servo motor is fixedly connected to the connecting shaft, and the servo motor controls the turntable to rotate intermittently.
[0031] The reagent disk is buckled with an end cover, which is opened before performing step B.
[0032] The end cover is hinged at the edge of the reagent disk, and a cylinder is arranged between the reagent disk and the end cover, and a piston rod of the cylinder can drive the end cover to swing relative to the reagent disk.
[0033] The connecting shaft is also provided with a second sensor, and the second sensor is used to detect whether the end cover is opened.
[0034] The sensor 1 and the sensor 2 are both connected to the controller, and the controller can control the turntable or the end cover to perform corresponding actions after receiving the above signal.
[0035] The loader is adjacent to the reagent disk. In the initial state, the reagent needle on the loader is in the initial position, and there is an appropriate amount of reagent in the reagent needle.
[0036] After both sensor 1 and sensor 2 are triggered, the controller sends a corresponding signal.
[0037] First, the end cover is opened, then the reagent needle is rotated to the corresponding storage part of the reagent disk, and finally an appropriate amount of reagent is input into the corresponding storage part through the reagent needle to ensure that it can work normally.
[0038] After the reagent is added, the rear end cover and reagent needle are reset.
[0039] Of course, during the operation, the loader in the initial state rotates together with the reagent disk.
[0040] The reagent loading method in this operating state controls the loader to rotate to a set position and add an appropriate amount of reagent through a controller. Therefore, the reagent tray that does not need to be operated during the adding process stops rotating, and the degree of automation is relatively high.
[0041] At the same time, adding an appropriate amount of reagent into the reagent needle in advance can ensure the stable operation of the reagent disk. The operation is relatively simple and has high practical value.
[0042] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0043] Those skilled in the art should recognize that the above embodiments are only used to illustrate the present invention, and are not intended to limit the present invention. As long as they are within the spirit of the present invention, appropriate changes and modifications to the above embodiments are within the scope of protection claimed by the present invention.
Claims
1. A reagent loading method in a running state, wherein a reagent disk and a loader having a reagent needle are arranged adjacent to each other, characterized in that: The reagent disk is in the shape of a disk and has a plurality of storage parts for storing reagent bottles or reagent tubes along its circumference. A controller capable of receiving and sending signals is provided between the reagent disk and the loader. The loading method includes the following steps: Detection: Each storage part of the reagent disk has a corresponding detector, which can detect whether the corresponding storage part has an appropriate amount of reagent. When the detector detects that the amount of reagent in the corresponding storage part is less than the set amount, the controller sends a corresponding coded signal to the loader; Execute adding: after the loader with the reagent needle receives the above number signal, the loader rotates relative to the reagent disk until the reagent needle on it is located directly above the corresponding storage part, and the reagent needle delivers the corresponding amount of reagent to the storage part; C. Reset: After the loader completes the adding operation, the loader resets to the initial position.
2. The reagent loading method in the running state according to claim 1, characterized in that: Each storage part has a corresponding digital identification A, the missing reagent signal at the storage part is B, and the above numbered signal is A+B.
3. The reagent loading method in the running state according to claim 1, characterized in that: The detector is a CCD camera.
4. The reagent loading method in the running state according to claim 2, characterized in that: The detector is sensor one.
5. The reagent loading method in the running state according to claim 4, characterized in that: The loader comprises a turntable and a reagent needle fixedly connected to the turntable. A connecting shaft is fixedly connected to the center of the reagent disk. The turntable is sleeved on the connecting shaft and can rotate intermittently relative to the connecting shaft.
6. The reagent loading method in the running state according to claim 5, characterized in that: A servo motor is fixedly connected to the connecting shaft, and the servo motor controls the turntable to rotate intermittently.
7. The reagent loading method in the running state according to claim 6, characterized in that: The reagent disk is buckled with an end cover, which is opened before performing step B.
8. The reagent loading method in the running state according to claim 7, characterized in that: The end cover is hinged at the edge of the reagent disk, and a cylinder is arranged between the reagent disk and the end cover, and a piston rod of the cylinder can drive the end cover to swing relative to the reagent disk.
9. The reagent loading method in the running state according to claim 8, characterized in that: The connecting shaft is also provided with a second sensor, and the second sensor is used to detect whether the end cover is opened.
10. The reagent loading method in the running state according to claim 9, characterized in that: The sensor 1 and the sensor 2 are both connected to the controller, and the controller can control the turntable or the end cover to perform corresponding actions after receiving the above signal.