Purification processing equipment for heparin

By adopting the heating air supply structure and the design of multiple rows of wind conductors in heparin purification equipment, the problem of low evaporation and concentration efficiency is solved, efficient purification and automated processing are achieved, the stability and safety of the equipment are improved, and the high performance is met. Production demand for quality products.

CN222130990UActive Publication Date: 2024-12-10HAOTAI JUYUAN (JILIN) PHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202422629297.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-30
Publication Date
2024-12-10
Estimated Expiration
2034-10-30

AI Technical Summary

Technical Problem

The existing heparin purification equipment adopts traditional evaporation and concentration method, which has low efficiency and cannot meet the needs of efficient purification and quality control.

Method used

A heparin purification processing equipment including a heating air supply structure and multiple rows of wind conductors was designed. Through the combination of the ring air duct and wind conductor, the hot air is uniformly distributed, the evaporation and concentration efficiency is improved, and filter filling is installed in the inlet bellows for purification. A discharge hole and a windshield basin are designed at the bottom of the box to reduce manual cleaning work, and an electric roller and a uniform rod are installed in the upper box cover to realize automatic material processing.

Benefits of technology

It improves purification efficiency and uniformity, reduces the difficulty of manpower operation, increases the stability and safety of the equipment, reduces the probability of failure, ensures the high purity and safety of the product, and complies with GMP specifications.

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Abstract

The utility model discloses heparin purification processing equipment, which relates to the technical field of purification equipment, solves the technical problem of low efficiency in the prior art, and comprises a main base, a stand column is fixedly mounted on the upper wall surface of the main base, a purification box is fixedly mounted on the stand column, an upper box cover is fixedly mounted on the upper wall surface of the purification box, and a lower box cover is fixedly mounted on the lower wall surface of the purification box. According to the device disclosed by the utility model, airflow heating is carried out through the heating air supply structure, so that evaporation and concentration can be more efficiently realized, the purification efficiency is improved, and the problem of low efficiency of a traditional method is solved; and by adopting the design of combining the annular air pipe and the multiple rows of air guide heads, hot air can be uniformly distributed in the purification box, so that the uniformity and high efficiency of the purification process are ensured.
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Description

Technical Field

[0001] The utility model relates to the technical field of purification equipment, in particular to a purification and processing equipment for heparin. Background Art

[0002] The utility model relates to the technical field of organic chemical purification equipment. The main purpose of heparin purification equipment in organic chemistry is to extract and purify heparin from biological source materials, which is an important biochemical molecule and drug. Purification equipment improves the purity of heparin by removing impurities to ensure its safety and effectiveness in biological and pharmaceutical applications. In addition, these devices help to achieve strict quality control and ensure the consistency of products, including their molecular weight, degree of sulfation and biological activity, which is crucial for pharmaceutical applications. The efficient purification process improves yield, reduces the waste of raw materials, reduces production costs and improves economic benefits. At the same time, the use of equipment helps products meet international quality standards and regulatory requirements to ensure market compliance. The purification process also specifically removes possible toxic components, reduces toxicity and improves the safety of drugs. In short, heparin purification equipment plays a key role in the fields of organic chemistry and pharmacy to ensure that the specifications and quality of the final product meet various application requirements.

[0003] Heparin purification and processing equipment has important functions and significance in the biochemical and pharmaceutical industries. Its core function is to purify high-quality heparin. By using technologies such as filtration, centrifugation, and chromatography, the equipment can effectively remove impurities and inactive ingredients to ensure the high purity of the product. In addition, these equipment have a sophisticated quality control system to ensure that the purity, activity, and molecular weight of each batch of products are consistent and meet pharmaceutical standards, thereby ensuring product quality. The efficient purification process not only improves the utilization rate of raw materials and reduces production costs, but also optimizes the production process and improves economic benefits. By removing possible toxic substances and allergens, the equipment also improves the safety of drugs and meets GMP and other regulatory requirements. In response to the market demand for high-quality heparin products, the efficient performance of the equipment ensures the feasibility of large-scale production and the stable supply of products, helping companies to quickly respond to market changes and customer needs. Therefore, heparin purification and processing equipment is crucial in the production of heparin. Through its professional functions, it provides efficient, safe, and economical solutions for the pharmaceutical industry, promoting the industry's technological progress and the improvement of market competitiveness.

[0004] The existing technology adopts the traditional evaporation concentration method, which has the technical problem of low efficiency. Utility Model Content

[0005] In view of the deficiencies of the prior art, the utility model provides a heparin purification and processing device, which solves the technical problem of low efficiency in the prior art.

[0006] To achieve the above objectives, the utility model is implemented through the following technical solutions: a heparin purification and processing equipment, including a main base, a column is fixedly installed on the upper wall of the main base, a purification box is fixedly installed on the column, an upper box cover is fixedly installed on the upper wall of the purification box, a medicine adding box is fixedly installed on the upper wall of the column, a drug guide tube is fixedly installed on the output end of the medicine adding box, the output end of the drug guide tube is connected to the upper box cover, the output end of the drug guide tube is connected to a spray head, a discharge hole is opened at the lower end of the purification box, and a heating and air supply structure is installed on the purification box.

[0007] Preferably, the heating and air supply structure includes an air inlet box, which is fixedly installed on the upper wall of the column, an air supply fan is fixedly installed on the upper end of the air inlet box, a resistance heating plate is fixedly installed inside the air inlet box, an annular air duct is fixedly installed outside the purification box, the annular air duct is connected to the output end of the air inlet box, an air guide head is fixedly installed on the upper end of the annular air duct, the output end of the air guide head is connected to the inner wall of the purification box, an upper exhaust duct is provided at the upper end of the purification box, and a lower exhaust duct is provided at the lower end of the purification box.

[0008] Preferably, the air guide heads are evenly spaced and installed on the side wall of the purification box, and each row of the air guide heads is evenly arranged vertically.

[0009] Preferably, a filter filler is fixedly installed in the air inlet box, and a protective frame is fixedly installed at the input end of the air inlet box.

[0010] Preferably, a wind shield basin is fixedly installed at the lower end of the purification box, and a straight pipe is opened at the lower end of the wind shield basin, and the straight pipe is installed in the discharge hole.

[0011] Preferably, a bracket is fixedly installed in the upper box cover, an electric roller is installed in the bracket, and a material leveling rod is fixedly installed on the electric roller.

[0012] Beneficial Effects

[0013] The utility model provides a purification and processing equipment for heparin. The utility model heats the air flow through a heating air supply structure, can more efficiently realize evaporation and concentration, improves the purification efficiency, and solves the problem of low efficiency of traditional methods; the design of combining a ring air duct with a multi-row air guide head allows the hot air to be evenly distributed inside the purification box, ensuring the uniformity and efficiency of the purification process; a filter filler is provided in the air inlet box, which can preliminarily filter the air entering the equipment, ensuring the cleanliness of the operating environment; the discharge hole and wind shield basin design at the bottom of the purification box are provided with a straight discharge pipe, which can quickly discharge the product, thereby reducing the workload of manual cleaning; the electric roller and material leveling rod design in the upper box cover can automatically and evenly process the material, further improving the production efficiency and reducing the difficulty of manual operation; the fixed installation between the components increases the stability of the equipment and reduces the probability of failure. At the same time, the setting of the protective frame also improves the safety of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the main structure of a heparin purification and processing equipment described in the utility model.

[0015] In the figure: 1. Main base; 2. Column; 3. Purification box; 4. Upper box cover; 5. Dosing box; 6. Drug guide pipe; 7. Sprinkler head; 8. Air inlet box; 9. Air supply fan; 10. Resistance heating plate; 11. Circular air duct; 12. Air guide head; 13. Upper exhaust duct; 14. Lower exhaust duct; 15. Filter filling; 16. Protective frame; 17. Wind shield; 18. Straight pipe; 19. Bracket; 20. Electric roller; 21. Material leveling rod; DETAILED DESCRIPTION

[0016] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined purpose of the utility model, the technical scheme in the embodiment of the utility model will be clearly and completely described below in combination with the drawings in the embodiment of the utility model. Obviously, the described embodiment is only a part of the embodiment of the utility model, rather than all the embodiments. The detailed description is as follows.

[0017] See also Figure 1 The utility model provides a technical solution: a heparin purification and processing equipment, comprising a main base 1, a column 2 is fixedly installed on the upper wall of the main base 1, a purification box 3 is fixedly installed on the column 2, an upper box cover 4 is fixedly installed on the upper wall of the purification box 3, a medicine adding box 5 is fixedly installed on the upper wall of the column 2, a medicine guiding tube 6 is fixedly installed at the output end of the medicine adding box 5, the output end of the medicine guiding tube 6 is connected to the upper box cover 4, the output end of the medicine guiding tube 6 is connected to a spray head 7, a discharge hole is opened at the lower end of the purification box 3, and a heating and air supply structure is installed on the purification box 3.

[0018] The present embodiment is further configured as follows: the heating and air supply structure includes an air inlet box 8, the air inlet box 8 is fixedly mounted on the upper wall of the column 2, an air supply fan 9 is fixedly mounted on the upper end of the air inlet box 8, a resistance heating plate 10 is fixedly mounted inside the air inlet box 8, a ring air duct 11 is fixedly mounted outside the purification box 3, the ring air duct 11 is connected to the output end of the air inlet box 8, an air guide head 12 is fixedly mounted on the upper end of the ring air duct 11, and the output end of the air guide head 12 is connected to the inner wall of the purification box 3, an upper exhaust duct 13 is provided at the upper end of the purification box 3, and a lower exhaust duct 14 is provided at the lower end of the purification box 3.

[0019] The present embodiment is further configured such that the air guide heads 12 are evenly spaced and installed on the side wall of the purification box 3 , and each row of the air guide heads 12 is evenly arranged vertically.

[0020] This embodiment is further configured such that a filter filler 15 is fixedly installed in the air inlet box 8 , and a protective frame 16 is fixedly installed at the input end of the air inlet box 8 .

[0021] The present embodiment is further configured such that a wind shielding basin 17 is fixedly installed at the lower end of the purification box 3, a straight pipe 18 is opened at the lower end of the wind shielding basin 17, and the straight pipe 18 is installed in the discharge hole.

[0022] The present embodiment is further configured such that a bracket 19 is fixedly installed in the upper box cover 4 , an electric roller 20 is installed in the bracket 19 , and a material leveling rod 21 is fixedly installed on the electric roller 20 .

[0023] The detailed connection means are well known in the art; Figure 1 As shown, preparations:

[0024] Make sure the equipment is installed securely and connected to the necessary power and gas sources.

[0025] Check whether the various components of the equipment are working properly, including the air supply fan 9, the resistance heating plate 10 and the electric roller 20.

[0026] Make sure that the drug adding box 5 contains the raw material liquid that needs to be processed, and check whether the connection between the drug guiding pipe 6 and the spray head 7 is normal.

[0027] Turn on the power of the equipment, start the air supply fan 9 and the resistance heating plate 10 in the air inlet box 8, and also start the electric roller 20 in the upper box cover 4.

[0028] Ensure that the filtration system in the air inlet box 8 works properly to provide a clean hot air flow.

[0029] The drug adding tank 5 starts to add raw material liquid into the purification tank 3 through the drug guiding tube 6 .

[0030] The spray head 7 evenly sprays the liquid in the purification box 3 in a mist form.

[0031] The annular air duct 11 and the air guide head 12 ensure that the hot air can flow evenly through the interior of the purification box 3, thereby accelerating the evaporation and concentration of the liquid.

[0032] The evaporated concentrate is automatically discharged through the discharge hole at the bottom of the purification box 3.

[0033] After the purification process is completed, power off the device.

[0034] Check whether there is any residue inside the purification box 3 and the heating and air supply structure, and clean them if necessary to prepare for the next use.

[0035] Regularly inspect and maintain each component of the equipment to extend the service life of the equipment and ensure normal operation next time it is used.

[0036] The above description is only a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as a preferred embodiment as above, it is not intended to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A heparin purification and processing device, comprising a main base (1), characterized in that: A column (2) is fixedly mounted on the upper wall of the main base (1), a purification box (3) is fixedly mounted on the column (2), an upper box cover (4) is fixedly mounted on the upper wall of the purification box (3), a medicine adding box (5) is fixedly mounted on the upper wall of the column (2), a medicine guiding tube (6) is fixedly mounted on the output end of the medicine adding box (5), the output end of the medicine guiding tube (6) is connected to the upper box cover (4), the output end of the medicine guiding tube (6) is connected to a spray head (7), a discharge hole is opened at the lower end of the purification box (3), and a heating and air supply structure is mounted on the purification box (3).

2. A heparin purification and processing equipment according to claim 1, characterized in that The heating air supply structure comprises an air inlet box (8), the air inlet box (8) is fixedly mounted on the upper wall surface of the column (2), an air supply fan (9) is fixedly mounted on the upper end of the air inlet box (8), a resistance heating plate (10) is fixedly mounted inside the air inlet box (8), a ring air duct (11) is fixedly mounted outside the purification box (3), the ring air duct (11) is connected to the output end of the air inlet box (8), an air guide head (12) is fixedly mounted on the upper end of the ring air duct (11), the output end of the air guide head (12) is connected to the inner wall surface of the purification box (3), an upper exhaust duct (13) is arranged at the upper end of the purification box (3), and a lower exhaust duct (14) is arranged at the lower end of the purification box (3).

3. A heparin purification and processing equipment according to claim 2, characterized in that The air guide heads (12) are evenly spaced and installed on the side wall of the purification box (3), and each row of the air guide heads (12) is evenly arranged vertically.

4. A heparin purification and processing equipment according to claim 2, characterized in that A filter filler (15) is fixedly installed inside the air inlet box (8), and a protective frame (16) is fixedly installed at the input end of the air inlet box (8).

5. The heparin purification processing equipment according to claim 1, characterized in that A wind shield (17) is fixedly installed at the lower end of the purification box (3), and a straight pipe (18) is opened at the lower end of the wind shield (17), and the straight pipe (18) is installed in the discharge hole.

6. The heparin purification processing equipment according to claim 1, characterized in that A bracket (19) is fixedly installed in the upper box cover (4), an electric roller (20) is installed in the bracket (19), and a material leveling rod (21) is fixedly installed on the electric roller (20).