Diaphragm structure, sampling tube and biological sample detection device

Abstract

The utility model relates to a diaphragm structure, sampling tube and biological sample detection device, including mounting ring and diaphragm, be equipped with fluid channel in the mounting ring, said diaphragm is perpendicular to the axis of mounting ring, the outer edge of diaphragm is connected to the inner wall of mounting ring; the mounting ring and the diaphragm are integrally formed by rubber or silica gel, and the thickness of the diaphragm is not larger than 1 mm. The independent diaphragm structure is adopted, the main cavity can be isolated from the communicating cavity by installing the diaphragm structure on the sampling pipe, and the diaphragm structure is integrally simple and convenient to process and manufacture.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical equipment, and specifically relates to a diaphragm structure, a sampling tube and a biological sample detection device. Background Art

[0002] With the continuous outbreak and spread of infectious diseases around the world, rapid and accurate detection of pathogens has become a key step in preventing and controlling infectious diseases. However, traditional methods for detecting infectious markers have problems with sample contamination and transmission risks, mainly open lateral flow test cards, which are prone to sample cross-contamination during operation.

[0003] Chinese patent authorization announcement number CN214278200U discloses a fully sealed pre-pressurized sampling, storage and testing integrated medical tube, which pre-injects sample liquid into the main cavity. During testing, the cross-collected sample is placed in the main cavity, the pull strip is pulled open, and then the bottom surface is pushed upward by the lower push piece, and the bottom surface is pierced, so that the liquid enters the bottom cavity and contacts the test strip, thereby achieving the purpose of testing. However, what is pierced is the bottom surface of the main cavity, which is an integrated structure with the tube body. When processing the tube body, an injection molding process is usually used, and such a thin bottom surface is difficult to be directly injection molded on the tube body, thereby increasing the difficulty of processing. Utility Model Content

[0004] In view of this, the utility model provides a diaphragm structure, a sampling tube and a biological sample detection device. An independent diaphragm structure is adopted and installed on the sampling tube to isolate the main cavity from the connecting cavity. The diaphragm structure is simple as a whole and is easy to process and manufacture.

[0005] The technical solution adopted by the utility model is:

[0006] A diaphragm structure, used in a biological sample detection device, comprises a mounting ring and a diaphragm, wherein a fluid channel is formed in the mounting ring, the diaphragm is perpendicular to the axis of the mounting ring, and the outer edge of the diaphragm is connected to the inner wall of the mounting ring; the mounting ring and the diaphragm are integrally formed of rubber or silicone, and the thickness of the diaphragm is not greater than 1 mm.

[0007] Preferably, an annular sealing ring is further provided on the outer peripheral wall of the mounting ring along the circumference of the mounting ring.

[0008] Preferably, there are two sealing rings, and the two sealing rings are spaced apart in the axial direction of the mounting ring.

[0009] Preferably, the diaphragm is located in the middle of the mounting ring, the two sealing rings are respectively located on both sides of the diaphragm, and in the axial direction, the distances between the two sealing rings and the diaphragm are equal.

[0010] Preferably, in the circumferential direction of the mounting ring, the fluid channel includes a first equal-diameter section, a second equal-diameter section and a third equal-diameter section connected in sequence, the diameter of the first equal-diameter section is equal to the diameter of the third equal-diameter section, the diameter of the second equal-diameter section is smaller than the diameter of the first equal-diameter section, and the diaphragm is located in the second equal-diameter section.

[0011] Preferably, the fluid channel further comprises a first diameter-reducing section and a second diameter-reducing section, the first constant diameter section and the second constant diameter section are connected via the first diameter-reducing section, the second constant diameter section and the third constant diameter section are connected via the second diameter-reducing section, the diameter of the first diameter-reducing section gradually decreases along the direction from the first constant diameter section to the second constant diameter section, the diameter of the large end of the first diameter-reducing section is equal to the diameter of the first constant diameter section and is connected to the first constant diameter section, the diameter of the small end of the first diameter-reducing section is equal to the diameter of the second constant diameter section and is connected to the second constant diameter section;

[0012] Along the direction from the second equal-diameter section to the third equal-diameter section, the diameter of the second diameter-changing section gradually increases, the diameter of the small end of the second diameter-changing section is equal to the diameter of the second equal-diameter section and is connected to the second equal-diameter section, and the diameter of the large end of the second diameter-changing section is equal to the diameter of the third equal-diameter section and is connected to the third equal-diameter section.

[0013] The utility model also relates to a sampling tube, comprising a tube body, a test paper strip and the aforementioned diaphragm structure, wherein the upper portion of the tube body forms a first opening, the tube body is provided with a main cavity, a connecting cavity and a test paper cavity, the upper portion of the main cavity is connected to the first opening, the main cavity and the test paper cavity are arranged side by side, and the lower portion of the main cavity and the lower portion of the test paper cavity are both connected to the connecting cavity;

[0014] The diaphragm structure is provided at the bottom of the main cavity, and the diaphragm structure seals the lower end of the main cavity so that the main cavity and the connecting cavity are not connected to each other;

[0015] The test paper strip is inserted into the test paper cavity, and the lower end of the test paper strip extends into the connecting cavity.

[0016] Preferably, an annular stop ring is provided on the inner wall of the main cavity, the outer periphery of the stop ring is fixedly connected to the inner wall of the main cavity, and the stop ring is located at the lower end of the main cavity;

[0017] The outer diameter of the mounting ring matches the inner diameter of the main cavity, the outer wall of the mounting ring is sealed and fitted with the inner wall of the main cavity, and the lower end of the mounting ring abuts against the stop ring.

[0018] Preferably, the main cavity comprises a first cavity and a second cavity connected up and down, the first cavity is located on the upper side of the second cavity, the second cavity is a vertical columnar space, and the diaphragm structure is installed in the second cavity.

[0019] The utility model also relates to a biological sample detection device, comprising a sampling assembly and the aforementioned sampling tube, wherein the sampling assembly comprises an upper cover and a sampling rod, wherein the sampling rod is connected to the upper cover, wherein a sampling head is provided at the lower part of the sampling rod, wherein the lower end of the sampling head is sharp, wherein the sampling rod extends from the first opening into the main cavity, and wherein the sampling assembly has a first station and a second station relative to the diaphragm structure;

[0020] At the first station, the sampling rod is located on the upper side of the diaphragm structure;

[0021] At the second station, the lower end of the sampling head punctures the diaphragm.

[0022] Beneficial effects of the utility model:

[0023] The diaphragm structure of the utility model is composed of a mounting ring and a diaphragm as a whole, and is made of rubber or silicone, so the overall structure is simple, which facilitates the processing and manufacturing of the diaphragm structure. When applied to a biological sample detection device, it is installed at the bottom of the main cavity, thereby achieving the purpose of isolating the main cavity from the connecting cavity. Therefore, there is no need to set the bottom surface in the background technology on the tube body of the sampling tube, which reduces the difficulty of processing the tube body. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The above and other purposes, features and advantages of the present invention will become more apparent through the following description of the embodiments of the present invention with reference to the accompanying drawings, in which:

[0025] Figure 1 is a schematic diagram of the structure of the diaphragm structure;

[0026] Figure 2 is a cross-sectional view of the diaphragm structure;

[0027] Figure 3 It is a schematic diagram of the structure of the sampling tube;

[0028] Figure 4 is a cross-sectional view of the sampling tube;

[0029] Figure 5 yes Figure 4 A magnified view of part A;

[0030] Figure 6 is a schematic diagram of the structure of a biological sample detection device;

[0031] Figure 7 It is a schematic diagram of the structure of the sampling component;

[0032] Figure 8 is a cross-sectional view of a biological sample detection device at the first station;

[0033] Fig. 9 It is a cross-sectional view of the second station, a biological sample detection device.

[0034] In the figure: 1. diaphragm structure; 2. tube body;

[0035] 11. Mounting ring; 12. Diaphragm; 13. Sealing ring;

[0036] 21. Main cavity; 22. Connecting cavity; 23. Test paper cavity; 24. Test paper strip;

[0037] 31. Sampling rod; 32. Sampling head; 33. Upper cover;

[0038] 111, first equal diameter section; 112, second equal diameter section; 113, third equal diameter section; 114, first reduced diameter section; 115, second reduced diameter section;

[0039] 211. First cavity; 212. Second cavity; 213. Stop ring. DETAILED DESCRIPTION

[0040] The present invention is described below based on embodiments, but the present invention is not limited to these embodiments. In the following detailed description of the present invention, some specific details are described in detail. In order to avoid confusing the essence of the present invention, known methods, processes, procedures, and components are not described in detail.

[0041] In addition, persons of ordinary skill in the art will appreciate that the drawings provided herein are for illustration purposes and are not necessarily drawn to scale.

[0042] Unless the context clearly requires otherwise, throughout the specification and claims, the words "include", "comprising" and similar words should be interpreted in an inclusive sense rather than an exclusive or exhaustive sense; that is, in the sense of "including but not limited to".

[0043] In the description of the present invention, it should be understood that the terms "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. In addition, in the description of the present invention, unless otherwise specified, the meaning of "plurality" is two or more.

[0044] See also Figure 1-Figure 9The utility model provides a diaphragm structure for a biological sample detection device, including a mounting ring 11 and a diaphragm 12, wherein a fluid channel is formed in the mounting ring 11, the diaphragm 12 is perpendicular to the axis of the mounting ring 11, and the outer edge of the diaphragm 12 is connected to the inner wall of the mounting ring 11; the mounting ring 11 and the diaphragm 12 are integrally formed of rubber or silicone, and the thickness of the diaphragm 12 is not greater than 1 mm.

[0045] In the present invention, the biological sample detection device is used to detect biological samples, such as feces, respiratory skin tissue or body fluids. The function of the diaphragm structure 1 in the biological sample detection device is to isolate the main cavity 21 from the connecting cavity 22. When the main cavity 21 and the connecting cavity 22 need to be connected, the diaphragm 12 in the diaphragm structure 1 can be punctured.

[0046] In order to facilitate the understanding of the present invention, the diaphragm structure 1 is applied to a biological sample detection device as an example for explanation. The biological sample detection device includes a sampling tube and a sampling assembly. The sampling tube includes a tube body 2, a test strip 24 and a diaphragm structure 1. The upper part of the tube body 2 forms a first opening. The tube body 2 is provided with a main cavity 21, a connecting cavity 22 and a test paper cavity 23. The upper part of the main cavity 21 is connected to the first opening. The main cavity 21 and the test paper cavity 23 are arranged side by side on the left and right. The lower part of the main cavity 21 and the lower part of the test paper cavity 23 are both connected to the connecting cavity 22.

[0047] The diaphragm structure 1 is disposed at the bottom of the main cavity 21 , and the diaphragm structure 1 seals the lower end of the main cavity 21 , so that the main cavity 21 and the connecting cavity 22 are not connected to each other.

[0048] The test paper strip 24 is inserted into the test paper cavity 23 , and the lower end of the test paper strip 24 extends into the connecting cavity 22 .

[0049] The sampling assembly includes an upper cover 33 and a sampling rod 31, wherein the sampling rod 31 is connected to the upper cover 33, and a sampling head 32 is provided at the lower part of the sampling rod 31, and the lower end of the sampling head 32 is sharp, and the sampling rod 31 extends from the first opening into the main cavity 21, and the sampling assembly has a first station and a second station relative to the diaphragm structure 1;

[0050] In the first station, the sampling rod 31 is located on the upper side of the diaphragm structure 1;

[0051] At the second station, the lower end of the sampling head 32 punctures the diaphragm 12 .

[0052] Initially, the sampling rod 31 (sampling assembly) is in the first position relative to the sampling tube, and the main cavity 21 is pre-stored with a solvent, and the solvent is located on the upper side of the diaphragm structure 1. Due to the barrier of the diaphragm structure 1, the solvent cannot flow into the connecting cavity 22. At this time, the sampling head 32 is basically immersed in the solvent of the main cavity 21, and then the sampling assembly is pulled out, and the biological sample is collected through the sampling assembly. After the collection is completed, the sampling assembly is re-inserted into the main cavity 21 from the first opening, and the sampling head 32 is immersed again. When the sampling head 32 enters the solvent (reaches the first station), the biological sample attached to the sampling head 32 will dissolve into the solvent. The sampling assembly is pressed down continuously. Since the lower end of the sampling head 32 is sharp, the sampling head 32 will pierce the diaphragm 12, so that the main cavity 21 is connected with the connecting cavity 22, and the solvent will flow from the main cavity 21 into the connecting cavity 22. The lower end of the test strip 24 extends into the connecting cavity 22, so that the solvent contacts the lower end of the test strip 24, thereby causing the test strip 24 to change and display the test result.

[0053] In the above process, for the operator, after the sampling is completed, it is only necessary to insert the sampling component into the sampling tube and press down the sampling component, so the operation is more convenient.

[0054] The diaphragm structure 1 as a whole can be made of rubber or silicone, and the thickness of the diaphragm 12 is not more than 1 mm (for example, 0.1 mm, 0.3 mm, 0.5 mm, 0.8 mm or 1 mm, etc.). When the sampling head 32 is pressed down, the lower end of the sampling head 32 contacts the diaphragm 12 and punctures the diaphragm 12. Since the thickness of the diaphragm 12 itself is relatively small, the diaphragm 12 will be torn at the moment of being punctured, that is, the fluid channel is basically completely opened, thereby ensuring that the diaphragm 12 will not wrap around the sampling head 32 and ensuring that the solvent can flow into the connecting cavity 22.

[0055] An annular sealing ring 13 is also provided on the outer peripheral wall of the mounting ring 11 along the circumference of the mounting ring 11 .

[0056] The overall outer diameter of the mounting ring 11 matches the main cavity 21, and a sealing ring 13 is provided on the outer wall of the mounting ring 11, so that when the diaphragm structure 1 is installed in the main cavity 21, the inner wall of the main cavity 21 can be squeezed and matched with the diaphragm structure 1, thereby improving the sealing between the mounting ring 11 and the inner wall of the main cavity 21.

[0057] There are two sealing rings 13, and the two sealing rings 13 are arranged at intervals in the axial direction of the mounting ring 11. The two sealing rings 13 are arranged to further improve the sealing performance.

[0058] The diaphragm 12 is located in the middle of the mounting ring 11 , and the two sealing rings 13 are respectively located on both sides of the diaphragm 12 , and in the axial direction, the distances between the two sealing rings 13 and the diaphragm 12 are equal.

[0059] In the axial direction of the mounting ring 11, the fluid channel includes a first equal-diameter section 111, a second equal-diameter section 112 and a third equal-diameter section 113 which are connected in sequence, the diameter of the first equal-diameter section 111 is equal to the diameter of the third equal-diameter section 113, the diameter of the second equal-diameter section 112 is smaller than the diameter of the first equal-diameter section 111, and the diaphragm 12 is located in the second equal-diameter section 112.

[0060] In actual application, when the sampling head 32 moves downward, the lower end of the sampling head 32 first enters the larger first equal-diameter section 111. Since the first equal-diameter section 111 has a larger diameter, it is convenient for the sampling head 32 to enter. Then, under the guidance of the first equal-diameter section 111, the lower end of the sampling head 32 can enter the second equal-diameter section 112, ensuring that the lower end of the sampling head 32 can successfully pierce the diaphragm 12.

[0061] The fluid channel also includes a first reducing section 114 and a second reducing section 115. The first equal diameter section 111 and the second equal diameter section 112 are connected via the first reducing section 114, and the second equal diameter section 112 and the third equal diameter section 113 are connected via the second reducing section 115. Along the direction from the first equal diameter section 111 to the second equal diameter section 112, the diameter of the first reducing section 114 gradually decreases. The diameter of the large end of the first reducing section 114 is equal to the diameter of the first equal diameter section 111 and is connected to the first equal diameter section 111. The diameter of the small end of the first reducing section 114 is equal to the diameter of the second equal diameter section 112 and is connected to the second equal diameter section 112.

[0062] Along the direction from the second equal diameter section 112 to the third equal diameter section 113, the diameter of the second diameter reducing section 115 gradually increases, the diameter of the small end of the second diameter reducing section 115 is equal to the diameter of the second equal diameter section 112 and is connected to the second equal diameter section 112, and the diameter of the large end of the second diameter reducing section 115 is equal to the diameter of the third equal diameter section 113 and is connected to the third equal diameter section 113.

[0063] In particular, the provision of the first reduced diameter section 114 can guide the lower end of the sampling head 32 to enter the second constant diameter section 112 , making it easier for the lower end of the sampling head 32 to pierce the diaphragm 12 .

[0064] The utility model also provides a sampling tube, including a tube body 2, a test strip 24 and the aforementioned diaphragm structure 1, wherein a first opening is formed at the upper portion of the tube body 2, and a main cavity 21, a connecting cavity 22 and a test paper cavity 23 are provided in the tube body 2, the upper portion of the main cavity 21 is connected to the first opening, the main cavity 21 and the test paper cavity 23 are arranged side by side on the left and right, and the lower portion of the main cavity 21 and the lower portion of the test paper cavity 23 are both connected to the connecting cavity 22.

[0065] The diaphragm structure 1 is disposed at the bottom of the main cavity 21 , and the diaphragm structure 1 seals the lower end of the main cavity 21 , so that the main cavity 21 and the connecting cavity 22 are not connected to each other.

[0066] The test paper strip 24 is inserted into the test paper cavity 23 , and the lower end of the test paper strip 24 extends into the connecting cavity 22 .

[0067] The specific function of the sampling tube has been described in the previous article and will not be repeated here.

[0068] An annular stop ring 213 is provided on the inner wall of the main cavity 21 . The outer periphery of the stop ring 213 is fixedly connected to the inner wall of the main cavity 21 . The stop ring 213 is located at the lower end of the main cavity 21 .

[0069] The outer diameter of the mounting ring 11 matches the inner diameter of the main cavity 21 , the outer wall of the mounting ring 11 is sealed and fitted with the inner wall of the main cavity 21 , and the lower end of the mounting ring 11 abuts against the stop ring 213 .

[0070] The setting of the stop ring 213 limits the position of the mounting ring 11 from the bottom. That is to say, when the sampling head 32 is pierced, the mounting ring 11 cannot move downward, so the sampling head 32 can only drive the center point of the diaphragm 12 to move downward, so that the diaphragm 12 forms a downward cone. As time goes by, the diaphragm 12 is pulled downward, making the diaphragm 12 gradually thinner until the sampling head 32 pierces the cone point. Since the diaphragm 12 is torn downward, the diaphragm 12 will be torn, ensuring that the solvent can flow downward into the connecting cavity 22.

[0071] The main cavity 21 includes a first cavity 211 and a second cavity 212 connected up and down. The first cavity 211 is located on the upper side of the second cavity 212. The second cavity 212 is a vertical columnar space. The diaphragm structure 1 is installed in the second cavity 212.

[0072] The utility model also provides a biological sample detection device, including a sampling component and the aforementioned sampling tube, the sampling component includes an upper cover 33 and a sampling rod 31, the sampling rod 31 is connected to the upper cover 33, a sampling head 32 is provided at the lower part of the sampling rod 31, the lower end of the sampling head 32 is sharp, the sampling rod 31 extends from the first opening into the main cavity 21, and the sampling component has a first station and a second station relative to the diaphragm structure 1.

[0073] In the first station, the sampling rod 31 is located on the upper side of the diaphragm structure 1 .

[0074] At the second station, the lower end of the sampling head 32 punctures the diaphragm 12 .

[0075] The specific structure and operation process of the biological sample detection device have been described in the previous text and will not be repeated here.

[0076] It should be understood that the above-mentioned embodiments are merely illustrative and not restrictive. Without departing from the basic principles of the present invention, various obvious or equivalent modifications or substitutions that can be made by technicians in this field to the above details will be included in the scope of the claims of the present invention.

Claims

1. A diaphragm structure for a biological sample detection device, characterized in that: It includes a mounting ring and a diaphragm, a fluid channel is formed in the mounting ring, the diaphragm is perpendicular to the axis of the mounting ring, and the outer edge of the diaphragm is connected to the inner wall of the mounting ring; the mounting ring and the diaphragm are made of rubber or silicone in one piece, and the thickness of the diaphragm is not more than 1mm.

2. The diaphragm structure according to claim 1, characterized in that: An annular sealing ring is also provided on the outer peripheral wall of the mounting ring along the circumference of the mounting ring.

3. The diaphragm structure according to claim 2, characterized in that: The number of the sealing rings is two, and the two sealing rings are spaced apart in the axial direction of the mounting ring.

4. The diaphragm structure according to claim 3, characterized in that: The diaphragm is located in the middle of the mounting ring, and the two sealing rings are respectively located on both sides of the diaphragm, and in the axial direction, the distances between the two sealing rings and the diaphragm are equal.

5. The diaphragm structure according to any one of claims 1 to 4, characterized in that: In the axial direction of the mounting ring, the fluid channel includes a first equal-diameter section, a second equal-diameter section and a third equal-diameter section connected in sequence, the diameter of the first equal-diameter section is equal to the diameter of the third equal-diameter section, the diameter of the second equal-diameter section is smaller than the diameter of the first equal-diameter section, and the diaphragm is located in the second equal-diameter section.

6. The diaphragm structure according to claim 5, characterized in that: The fluid channel further includes a first diameter-reducing section and a second diameter-reducing section, the first constant diameter section and the second constant diameter section are connected via the first diameter-reducing section, the second constant diameter section and the third constant diameter section are connected via the second diameter-reducing section, the diameter of the first diameter-reducing section gradually decreases along the direction from the first constant diameter section to the second constant diameter section, the diameter of the large end of the first diameter-reducing section is equal to the diameter of the first constant diameter section and is connected to the first constant diameter section, the diameter of the small end of the first diameter-reducing section is equal to the diameter of the second constant diameter section and is connected to the second constant diameter section; Along the direction from the second equal-diameter section to the third equal-diameter section, the diameter of the second diameter-changing section gradually increases, the diameter of the small end of the second diameter-changing section is equal to the diameter of the second equal-diameter section and is connected to the second equal-diameter section, and the diameter of the large end of the second diameter-changing section is equal to the diameter of the third equal-diameter section and is connected to the third equal-diameter section.

7. A sampling tube, characterized in that: The invention comprises a tube body, a test strip and the diaphragm structure according to any one of claims 1 to 6, wherein the upper part of the tube body forms a first opening, the tube body is provided with a main cavity, a connecting cavity and a test paper cavity, the upper part of the main cavity is connected with the first opening, the main cavity and the test paper cavity are arranged side by side, and the lower part of the main cavity and the lower part of the test paper cavity are both connected with the connecting cavity; The diaphragm structure is provided at the bottom of the main cavity, and the diaphragm structure seals the lower end of the main cavity so that the main cavity and the connecting cavity are not connected to each other; The test paper strip is inserted into the test paper cavity, and the lower end of the test paper strip extends into the connecting cavity.

8. The sampling tube according to claim 7, characterized in that: An annular stop ring is provided on the inner wall of the main cavity, the outer periphery of the stop ring is fixedly connected to the inner wall of the main cavity, and the stop ring is located at the lower end of the main cavity; The outer diameter of the mounting ring matches the inner diameter of the main cavity, the outer wall of the mounting ring is sealed and fitted with the inner wall of the main cavity, and the lower end of the mounting ring abuts against the stop ring.

9. The sampling tube according to claim 7, characterized in that: The main cavity includes a first cavity and a second cavity connected up and down, the first cavity is located on the upper side of the second cavity, the second cavity is a vertical columnar space, and the diaphragm structure is installed in the second cavity.

10. A biological sample detection device, characterized in that: The sampling assembly comprises a sampling tube as claimed in any one of claims 7 to 9, wherein the sampling assembly comprises an upper cover and a sampling rod, the sampling rod is connected to the upper cover, a sampling head is provided at the lower part of the sampling rod, the lower end of the sampling head is sharp, the sampling rod extends from the first opening into the main cavity, and the sampling assembly has a first station and a second station relative to the diaphragm structure; At the first station, the sampling rod is located on the upper side of the diaphragm structure; At the second station, the lower end of the sampling head punctures the diaphragm.

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