Small desktop chromatography device

Abstract

The utility model relates to a small desktop chromatography device which comprises a base, the top of the base is fixedly connected with two supporting plates, the tops of the supporting plates are fixedly connected with a top plate, the top plate is provided with a chromatography column, the top of the chromatography column is provided with a limiting ring, the bottom of the chromatography column is provided with a liquid outlet pipe, and the top of the liquid outlet pipe is provided with a liquid outlet. And a sealing rubber ring is arranged in the liquid outlet pipe. According to the small desktop chromatography device, a second electric push rod is started to clamp and fix an injector cylinder between a first clamping plate and a second clamping plate, after a substance needing chromatography is poured into a chromatography column, a piston of a third electric push rod stretches to drive an electric suction cup to move upwards to make contact with the piston of the injector, and the piston of the injector is sucked by the electric suction cup; at the moment, the third electric push rod contracts to drive the electric sucker and the injector piston to move downwards to extract the substances in the chromatographic column, so that the purification speed of the substances in the chromatographic column is accelerated, and the purification time is saved.

Description

Technical Field

[0001] The utility model relates to the technical field of chromatography, in particular to a small desktop chromatography device. Background Art

[0002] Chromatography is a separation and purification technology that is widely used in the fields of chemistry, biology, and pharmaceuticals. The chromatography column is the main body of chromatography technology, generally made of glass tubes or organic glass tubes. It is a purification method that separates the target sample based on the different distribution coefficients of each component in the sample mixture in the stationary phase and the mobile phase.

[0003] The chromatography process relies on external forces such as gravity, centrifugal force, and pressure. When the chromatography is carried out by gravity, the purification speed is relatively slow and the purification time is long. Therefore, a small desktop chromatography device is proposed to solve the above problems. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a small desktop chromatography device, which improves the purification speed and solves the above-mentioned problems.

[0005] To achieve the above object, the utility model provides the following technical solution: a small desktop chromatography device, comprising a base, two support plates are fixedly connected to the top of the base, a top plate is fixedly connected to the top of the support plate, a chromatography column is arranged on the top plate, a limiting ring is arranged on the top of the chromatography column, a liquid outlet pipe is arranged at the bottom of the chromatography column, and a sealing rubber ring is arranged inside the liquid outlet pipe;

[0006] The top of the top plate is hinged with a limiting plate, and the limiting plate can fit with the limiting ring on the chromatography column;

[0007] A fixing plate is fixedly connected to the top of the top plate, a first electric push rod is hinged on the right side of the fixing plate, and a piston of the first electric push rod is hinged to the limiting plate.

[0008] Furthermore, a limiting through slot is provided on the top plate, and the chromatography column can pass through the limiting through slot and penetrate the top plate, and the limiting ring on the chromatography column has a diameter larger than the limiting through slot.

[0009] Furthermore, a fixing rod is fixedly connected to the right side of the left support plate, a first clamping plate is fixedly connected to the right side of the fixing rod, a second electric push rod is fixedly connected to the left side of the right support plate, and a second clamping plate is fixedly connected to the left side of the piston of the second electric push rod.

[0010] Furthermore, a syringe barrel is arranged on the first clamping plate and the second clamping plate, a syringe head is arranged on the top of the syringe barrel, the syringe head can be plugged into the liquid outlet tube, and a syringe piston is slidably connected inside the syringe barrel.

[0011] Furthermore, a third electric push rod is fixedly connected to the top of the base, and an electric suction cup is fixedly connected to the top of the piston of the third electric push rod, and the electric suction cup is located directly below the syringe piston.

[0012] Compared with the prior art, the technical solution of this application has the following beneficial effects:

[0013] The small desktop chromatography device clamps and fixes the syringe barrel between the first clamping plate and the second clamping plate by starting the second electric push rod, and places the chromatography column on the top plate through the limiting groove and the limiting ring. After the substance to be chromatographed is poured into the chromatography column, the first electric push rod drives the limiting plate to rotate so that the limiting plate abuts against the limiting ring, thereby limiting the chromatography column. At this time, the liquid outlet tube is plugged into the syringe head through the sealing rubber ring, and the third electric push rod piston is extended to drive the electric suction cup to move up and contact the syringe piston. The electric suction cup sucks the syringe piston. At this time, the third electric push rod is contracted to drive the electric suction cup and the syringe piston to move down, so that the substance in the chromatography column is extracted, thereby accelerating the purification speed of the substance in the chromatography column and saving purification time. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a front cross-sectional structural schematic diagram of the utility model when the limit plate is in an open state;

[0015] Figure 2 This is a front view structural diagram of the utility model when the limit plate is in a closed state;

[0016] Figure 3 It is a partial top view structural schematic diagram of the utility model;

[0017] Figure 4 It is a partial bottom view of the structure of the utility model.

[0018] In the figure: 1. base; 2. support plate; 3. top plate; 301. limit groove; 4. chromatography column; 401. limit ring; 402. liquid outlet pipe; 403. sealing rubber ring; 5. limit plate; 6. fixing plate; 7. first electric push rod; 8. fixing rod; 9. first clamping plate; 10. second electric push rod; 11. second clamping plate; 12. syringe barrel; 13. syringe head; 14. syringe piston; 15. third electric push rod; 16. electric suction cup. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] See also Figure 1-4 , an embodiment provided by the utility model:

[0021] A small desktop chromatography device comprises a base 1, two support plates 2 are fixedly connected to the top of the base 1, a top plate 3 is fixedly connected to the top of the support plates 2, a chromatography column 4 is arranged on the top plate 3, a limiting ring 401 is arranged on the top of the chromatography column 4, a liquid outlet pipe 402 is arranged at the bottom of the chromatography column 4, and a sealing rubber ring 403 is arranged inside the liquid outlet pipe 402.

[0022] The top of the top plate 3 is hinged with a limiting plate 5 , and the limiting plate 5 can fit with the limiting ring 401 on the chromatography column 4 .

[0023] A fixing plate 6 is fixedly connected to the top of the top plate 3 , a first electric push rod 7 is hinged to the right side of the fixing plate 6 , and a piston of the first electric push rod 7 is hinged to the limit plate 5 .

[0024] Furthermore, the base 1, the support plate 2 and the top plate 3 support the device to maintain the stability of the overall structure of the device.

[0025] Furthermore, the diameter of the limiting groove 301 is smaller than the diameter of the limiting ring 401 , so that the top plate 3 supports the chromatography column 4 , and the chromatography column 4 plays a role in chromatographic purification of the substance inside it.

[0026] Furthermore, the liquid outlet tube 402 facilitates the discharge of substances in the chromatography column 4 , the sealing rubber ring 403 maintains the sealing of the connection between the liquid outlet tube 402 and the syringe head 13 , and the limiting plate 5 can fit with the limiting ring 401 to limit the chromatography column 4 .

[0027] Furthermore, the fixing plate 6 is hinged to the first electric push rod 7 to maintain the stability of the first electric push rod 7, and the piston of the first electric push rod 7 is hinged to the limit plate 5, so that the first electric push rod 7 can drive the limit plate 5 to rotate after starting.

[0028] Furthermore, the fixing rod 8 is fixedly connected to the first clamping plate 9 to maintain the stability of the first clamping plate 9, and the piston of the second electric push rod 10 is fixedly connected to the second clamping plate 11, so that the second electric push rod 10 can drive the second clamping plate 11 to move left and right after starting, and the first clamping plate 9 and the second clamping plate 11 play the role of clamping and fixing the syringe barrel 12.

[0029] Further, the syringe piston 14 is slidably connected to the syringe barrel 12, and when the syringe piston 14 is pulled downward, it plays the role of extracting the substance in the chromatography column 4.

[0030] Furthermore, the piston of the third electric push rod 15 is fixedly connected to the electric suction cup 16, so that the third electric push rod 15 can drive the electric suction cup 16 to move up and down after being started.

[0031] Working principle: by starting the second electric push rod 10, the syringe barrel 12 is clamped and fixed between the first clamping plate 9 and the second clamping plate 11, the chromatography column 4 is placed on the top plate 3 through the limiting groove 301 and the limiting ring 401, and after the substance to be chromatographed is poured into the chromatography column 4, the first electric push rod 7 drives the limiting plate 5 to rotate, so that the limiting plate 5 is against the limiting ring 401, thereby limiting the chromatography column 4. At this time, the liquid outlet pipe 402 is plugged into the syringe head 13 through the sealing rubber ring 403, and the piston of the third electric push rod 15 is extended, driving the electric suction cup 16 to move up and contact with the syringe piston 14. The electric suction cup 16 sucks the syringe piston 14. At this time, the third electric push rod 15 contracts, driving the electric suction cup 16 and the syringe piston 14 to move down, and the substance in the chromatography column 4 is extracted, thereby accelerating the purification speed of the substance in the chromatography column 4, saving purification time, and solving the problems raised in the background technology.

[0032] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0033] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A small desktop chromatography device, comprising a base (1), characterized in that: Two support plates (2) are fixedly connected to the top of the base (1); a top plate (3) is fixedly connected to the top of the support plate (2); a chromatography column (4) is arranged on the top plate (3); a limiting ring (401) is arranged on the top of the chromatography column (4); a liquid outlet pipe (402) is arranged at the bottom of the chromatography column (4); a sealing rubber ring (403) is arranged inside the liquid outlet pipe (402); A limiting plate (5) is hingedly connected to the top of the top plate (3), and the limiting plate (5) can fit with a limiting ring (401) on the chromatography column (4); The top of the top plate (3) is fixedly connected to a fixing plate (6), the right side of the fixing plate (6) is hingedly connected to a first electric push rod (7), and the piston of the first electric push rod (7) is hingedly connected to the limit plate (5).

2. A small desktop chromatography device according to claim 1, characterized in that: The top plate (3) is provided with a limiting through groove (301), and the chromatography column (4) can pass through the limiting through groove (301) through the top plate (3), and the limiting ring (401) on the chromatography column (4) has a diameter greater than the limiting through groove (301).

3. A small desktop chromatography device according to claim 1, characterized in that: A fixing rod (8) is fixedly connected to the right side of the left support plate (2), a first clamping plate (9) is fixedly connected to the right side of the fixing rod (8), a second electric push rod (10) is fixedly connected to the left side of the right support plate (2), and a second clamping plate (11) is fixedly connected to the left side of the piston of the second electric push rod (10).

4. A small desktop chromatography device according to claim 3, characterized in that: A syringe barrel (12) is arranged on the first clamping plate (9) and the second clamping plate (11), a syringe head (13) is arranged on the top of the syringe barrel (12), and the syringe head (13) can be plugged into the liquid outlet tube (402), and a syringe piston (14) is slidably connected to the inside of the syringe barrel (12).

5. A small desktop chromatography device according to claim 4, characterized in that: A third electric push rod (15) is fixedly connected to the top of the base (1), and an electric suction cup (16) is fixedly connected to the top of the piston of the third electric push rod (15), and the electric suction cup (16) is located directly below the syringe piston (14).

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