Synthesis device for producing creatine monohydrate

Abstract

The utility model belongs to the technical field of creatine monohydrate production equipment, and particularly relates to a creatine monohydrate production and synthesis device which comprises a pulping and centrifuging integrated mechanism, a thermal dissolving mechanism, a recrystallization reaction kettle, a liquid preparation tank and an acid liquid conveying system. The pulping and centrifuging integrated mechanism is used for pulping creatine monohydrate to remove most impurities in the creatine monohydrate intermediate product, particularly impurities mixed in the creatine monohydrate intermediate product, and the creatine monohydrate intermediate product is fed into the thermal dissolving mechanism to prepare a supersaturated solution after being centrifugally dewatered; the supersaturated solution is conveyed into the recrystallization reaction kettle for recrystallization, pure creatine monohydrate is obtained, impurities contained in the supersaturated solution prepared in the thermal dissolving device are few, and impurities contained in mother liquor generated by the recrystallization reaction kettle are few, so that the mother liquor can be recycled for multiple times, the discharge of waste liquor is reduced, and the production cost is reduced. Meanwhile, the yield of creatine monohydrate is improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of creatine monohydrate production equipment, in particular to a creatine monohydrate production and synthesis device. Background Art

[0002] Creatine (creatine monohydrate) is an important pharmaceutical raw material and health product additive. It can inhibit the generation of muscle fatigue factors, reduce fatigue and tension, restore physical strength, accelerate the synthesis of human protein, make muscles stronger, enhance muscle elasticity, reduce cholesterol, blood lipids and blood sugar levels, and also improve muscle atrophy in the middle-aged and elderly and delay aging. In recent years, creatine has developed into an important nutritional health product, which is favored by bodybuilders and athletes. The development prospects of creatine are very broad.

[0003] However, the existing domestic technology for producing creatine has problems such as many by-products and backward purification technology. Therefore, developing high yield while suppressing the occurrence of side reactions to improve the purity of creatine and reduce the discharge of wastewater in subsequent treatment processes, and achieving efficient and green production of high-purity creatine is of great significance to improving product quality and alleviating environmental problems. Summary of the invention

[0004] The utility model aims to provide a synthetic device for producing creatine monohydrate, which has the advantages of less by-products, good purification effect and less waste water.

[0005] To achieve the above-mentioned purpose, the technical solution adopted by the utility model is: to provide a device for producing and synthesizing creatine monohydrate, including a pulping and centrifugal integrated mechanism, a thermal dissolution mechanism, a recrystallization reactor, a liquid preparation tank and an acid liquid delivery system;

[0006] The supersaturated solution outlet of the thermal dissolution mechanism is connected to the liquid inlet of the recrystallization reactor through a pipeline, the mother liquid outlet of the recrystallization reactor is connected to the liquid preparation tank through a pipeline, the liquid preparation tank is equipped with a pH detection component, the liquid outlet of the acid delivery system is connected to the liquid preparation tank through a pipeline, and the liquid outlet of the liquid preparation tank is connected to the original liquid inlet of the thermal dissolution mechanism through a pipeline;

[0007] The integrated pulping and centrifugal mechanism includes a pulping component and a centrifugal dehydration component. The centrifugal dehydration component dehydrates the product of the pulping component, and the monohydrate creatine intermediate product produced by the centrifugal dehydration component is transported to the thermal dissolution mechanism for supersaturated solution configuration.

[0008] Optionally, it also includes a mother liquid renewal system, which includes a waste liquid discharge system and a new liquid replenishment system, and the new liquid replenishment system replenishes new mother liquid into the liquid preparation tank.

[0009] Optionally, a plurality of the recrystallization reactors are provided, and the plurality of the recrystallization reactors are incorporated between the thermal dissolution mechanism and the liquid preparation tank.

[0010] Optionally, the centrifugal beating integrated mechanism includes

[0011] A vertical cylinder, the top of which is open, the bottom of which is indented inward to form a protrusion, the outer side of which and the inner side of the vertical cylinder form an annular area, and the bottom of which is fixedly connected with a leg;

[0012] A liquid discharge port, which is fixedly mounted on the side of the vertical cylinder and communicates with the annular area;

[0013] A drive motor, wherein the drive motor is fixedly mounted on the bottom of the protruding portion with the output shaft facing upward, and the output shaft of the drive motor extends into the interior of the vertical cylinder;

[0014] A filter cylinder, the bottom of which is fixedly connected to the top flange of the output shaft of the driving motor, a transmission shaft is fixedly connected to the center of the inner bottom of the filter cylinder, and the top of the transmission shaft has a flower shaft section;

[0015] A first grinding disc, a separator disc, a second grinding disc and a feed disc, the first grinding disc and the second grinding disc are both transmission-connected to the flower axis segment, and an overflow gap is provided at the connection between the first grinding disc, the second grinding disc and the flower axis segment, the separator disc is rotationally connected to the flower axis segment through an installation kit, and the separator disc is located between the first grinding disc and the second grinding disc, the feed disc is fixedly installed on the inner side of the vertical cylinder, the ends of the feed disc and the separator disc are both provided with leakage holes, and the separator disc is fixedly connected to the vertical cylinder.

[0016] Optionally, an annular material storage area is provided on the top of the feed tray, the feed tray is sleeved on the flower axis section, and an upper cover is installed on the top of the vertical cylinder.

[0017] Optionally, the inner ring of the installation kit cooperates with the flower axis segment, the outer ring of the installation kit is annular, and the installation kit is rotatably installed with the separation disk.

[0018] Optionally, a side opening is provided on the side of the vertical cylinder, and a side door is hingedly installed at the side opening.

[0019] Optionally, the top of the first grinding disc and the bottom of the separation disc form a first grinding area, the top of the separation disc and the bottom of the second grinding disc form a second grinding area, and the top of the second grinding disc and the bottom of the feed disc form a third grinding area;

[0020] The first grinding area and the third grinding area are both inclined toward the center of the flower axis segment, and the second grinding area is inclined toward the outer contour of the separation disk.

[0021] Optionally, a drying mechanism and a crushing mechanism are further included, and the creatine monohydrate crystals produced by the recrystallization reactor are dried by the drying mechanism and crushed by the crushing mechanism to produce the product creatine monohydrate.

[0022] Compared with the prior art, the utility model has the following beneficial effects:

[0023] The utility model is provided with a pulping and centrifugal integrated mechanism, which performs pulping treatment on creatine monohydrate, removes most impurities in the creatine monohydrate intermediate product, especially impurities mixed in the creatine monohydrate intermediate product, and after centrifugal dehydration, sends it into a hot dissolution mechanism to configure a supersaturated solution, and the supersaturated solution is sent to a recrystallization reactor for recrystallization to obtain relatively pure creatine monohydrate.

[0024] At the same time, the impurities contained in the supersaturated solution configured in the thermal dissolution device are reduced, and the impurities contained in the mother liquor generated by the recrystallization reactor are reduced, so that the mother liquor can be recycled for multiple times, the discharge of waste liquid is reduced, and the yield of creatine monohydrate is improved.

[0025] Creatinine (a by-product, a high creatinine content will lead to an increased metabolic burden on the kidneys) is formed by a cyclization reaction of creatine under alkaline conditions. The reaction is a reversible reaction. Treating the generated product under acidic conditions can cause creatinine to undergo a ring-opening reaction to form creatine. The utility model is provided with a liquid preparation tank, and a pH detection component is used to detect the pH value of the solution inside the liquid preparation tank. When the pH value is greater than 6.5, the acid delivery system is controlled to add acid to the liquid preparation tank, so that the pickling step is completed simultaneously when the supersaturated solution is configured in the hot dissolution mechanism, thereby increasing the yield of creatine monohydrate and reducing the generation of by-product creatinine. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0027] Figure 1 It is a schematic diagram of the principle of an embodiment of the utility model;

[0028] Figure 2 It is a three-dimensional structural schematic diagram of the utility model's integrated pulping and centrifugal mechanism;

[0029] Figure 3 It is a front view structural schematic diagram of the utility model's integrated pulping and centrifugal mechanism;

[0030] Figure 4for Figure 3 Schematic diagram of the cross-sectional structure at AA in the middle;

[0031] Figure 5 for Figure 4 A schematic diagram of the enlarged structure at B in the middle;

[0032] Figure 6 It is a schematic diagram of the internal split three-dimensional structure of the centrifugal beating integrated mechanism of the utility model;

[0033] Figure 7 Schematic diagram of the reaction equation for creatinine ring opening and cyclization.

[0034] In the figure: 1. Pulping centrifugal integrated mechanism; 101. Vertical cylinder; 102. Side door; 103. Drain port; 104. Leg; 105. Annular area; 106. Protrusion; 107. Driving motor; 108. Filter cylinder; 109. Transmission shaft; 1010. Flower axis section; 1011. First grinding disc; 1012. Installation kit; 1013. Separation disc; 1014. Second grinding disc; 1015. Feed disc; 1016. Upper cover; 2. Thermal dissolution mechanism; 3. Recrystallization reactor; 4. Drying mechanism; 5. Crushing mechanism; 6. Liquid preparation tank; 7. Acid delivery system; 8. pH detection component; 9. New liquid replenishment system; 10. Waste liquid discharge system. DETAILED DESCRIPTION

[0035] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0036] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0037] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0038] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0039] Now, a device for producing and synthesizing creatine monohydrate provided by the embodiment of the utility model is described. Figure 1-7 As shown, a device for producing and synthesizing creatine monohydrate includes a pulping and centrifugal integrated mechanism 1, a thermal dissolution mechanism 2, a recrystallization reactor 3, a liquid preparation tank 6 and an acid liquid delivery system 7.

[0040] The integrated pulping and centrifugal mechanism 1 includes a pulping component and a centrifugal dehydration component. The centrifugal dehydration component is used to dehydrate the product of the pulping component. The monohydrate creatine intermediate product produced by the centrifugal dehydration component is transported (artificially transported) to the thermal dissolution mechanism 2 for supersaturated solution configuration.

[0041] Among them, the supersaturated solution outlet of the thermal dissolution mechanism 2 is connected to the liquid inlet of the recrystallization reactor 3 through a pipeline, the mother liquor outlet of the recrystallization reactor 3 is connected to the liquid preparation tank 6 through a pipeline, and the liquid preparation tank 6 is equipped with a pH detection component 8 for detecting the pH value of the liquid inside the liquid preparation tank 6, the liquid outlet of the acid liquid delivery system 7 is connected to the liquid preparation tank 6 through a pipeline, and the liquid outlet of the liquid preparation tank 6 is connected to the original liquid inlet of the thermal dissolution mechanism 2 through a pipeline.

[0042] The utility model provides a device for producing and synthesizing creatine monohydrate, which has the following advantages compared with the prior art:

[0043] Due to the provision of the integrated pulping and centrifuging mechanism 1, creatine monohydrate is pulped to remove most of the impurities in the creatine monohydrate intermediate product, especially the impurities mixed in the creatine monohydrate intermediate product. After centrifugal dehydration, it is sent to the hot dissolution mechanism 2 to prepare a supersaturated solution, and the supersaturated solution is sent to the recrystallization reactor 3 for recrystallization to obtain relatively pure creatine monohydrate.

[0044] At the same time, the impurities contained in the supersaturated solution configured in the thermal dissolution mechanism 2 are reduced, and the impurities contained in the mother liquor produced by the recrystallization reactor 3 are reduced, so that the mother liquor can be recycled for multiple times, reducing the discharge of waste liquid and improving the yield of creatine monohydrate.

[0045] Creatinine (a byproduct, high levels of which increase the metabolic burden on the kidneys) is formed by the cyclization of creatine under alkaline conditions. This reaction is reversible, and the resulting product can be treated under acidic conditions to cause creatinine to undergo a ring-opening reaction to form creatine (reference Figure 7), the utility model is provided with a liquid preparation tank 6, and a pH detection component 8 is used to detect the pH value of the solution inside the liquid preparation tank 6. When the pH value is greater than 6.5, the acid delivery system 7 is controlled to add acid to the liquid preparation tank 6, so that the pickling step is completed simultaneously when the supersaturated solution is configured in the hot dissolution mechanism 2, thereby improving the yield of creatine monohydrate and reducing the generation of by-product creatinine.

[0046] Another embodiment of the utility model is shown in Figure 1 , and also includes a mother liquor renewal system, the mother liquor renewal system includes a waste liquid discharge system 10 and a new liquid replenishment system 9, the new liquid replenishment system 9 is used to replenish new mother liquor into the liquid preparation tank 6, and the waste liquid discharge system 10 is used to discharge the mother liquor flowing out of the recrystallization reactor 3.

[0047] After the mother liquor has been circulated for many times, the impurity content in the mother liquor increases, which may affect the purity of the subsequent crystallized creatine monohydrate. Therefore, it is necessary to discharge part of the mother liquor and add some new mother liquor.

[0048] Specifically, the valve on the waste liquid discharge system 10 is opened to discharge a certain amount of waste mother liquid, and at the same time, the new liquid replenishment system 9 replenishes new mother liquid into the liquid preparation tank 6.

[0049] In another embodiment of the present invention, please refer to Figure 1 A plurality of recrystallization reactors 3 are provided, and the plurality of recrystallization reactors 3 are incorporated between the thermal dissolution mechanism 2 and the liquid preparation tank 6 to improve the efficiency of the recrystallization reaction.

[0050] In another embodiment of the present invention, refer to Figure 1 and Figure 6 The pulping centrifugal integrated mechanism 1 includes a vertical cylinder 101, a liquid discharge port 103, a driving motor 107, a filtering cylinder 108, a first grinding disc 1011, a separating disc 1013, a second grinding disc 1014 and a feeding disc 1015.

[0051] Among them, the top of the vertical cylinder 101 is open, and the bottom end of the vertical cylinder 101 is recessed inward to form a protrusion 106. The outer side of the protrusion 106 and the inner side of the vertical cylinder 101 form an annular area 105. The bottom of the vertical cylinder 101 is fixedly connected with a support leg 104, and the support leg 104 raises the vertical cylinder 101 to facilitate the installation of the drive motor 107. The drain port 103 is fixedly installed on the side of the vertical cylinder 101, and the drain port 103 is connected to the annular area 105. The drive motor 107 is fixedly installed at the bottom of the protrusion 106 with the output shaft facing upward, and the output shaft of the drive motor 107 extends to the inside of the vertical cylinder 101. The bottom of the filter cylinder 108 is fixedly connected to the top flange of the output shaft of the drive motor 107. The filter cylinder 108 A transmission shaft 109 is fixedly connected to the center position of the inner bottom, and a flower shaft section 1010 is provided at the top of the transmission shaft 109. The flower shaft section 1010 is used to transmit rotation. The first grinding disc 1011 and the second grinding disc 1014 are both transmission-connected to the flower shaft section 1010, and an overflow gap is provided at the connection between the first grinding disc 1011, the second grinding disc 1014 and the flower shaft section 1010. The separator disc 1013 is rotationally connected to the flower shaft section 1010 through the installation kit 1012, and the separator disc 1013 is located between the first grinding disc 1011 and the second grinding disc 1014. The feed disc 1015 is fixedly installed on the inner side of the vertical cylinder 101, and the ends of the feed disc 1015 and the separator disc 1013 are provided with leakage holes, and the separator disc 1013 is fixedly connected to the vertical cylinder 101.

[0052] The top of the first grinding disk 1011 and the bottom of the separating disk 1013 form a first grinding area, the top of the separating disk 1013 and the bottom of the second grinding disk 1014 form a second grinding area, and the top of the second grinding disk 1014 and the bottom of the feed disk 1015 form a third grinding area. Both the first grinding area and the third grinding area are inclined toward the center of the flower shaft segment 1010, and the second grinding area is inclined toward the outer contour of the separating disk 1013.

[0053] When in use, the crude creatine monohydrate is added to the feed tray 1015, and a pulping agent is pumped into the feed tray 1015 (impurities have a high solubility in the pulping agent, and creatine monohydrate is basically insoluble in the pulping agent, such as acetic acid, ethanol, etc.). The crude creatine monohydrate and the pulping agent are added to the feed tray 1015 together, and enter the third grinding area, the second grinding area and the first grinding area in sequence for grinding, and then enter the filter cylinder 108 for filtration to obtain the creatine monohydrate intermediate product.

[0054] In another embodiment of the present invention, please refer to Figures 2 to 6A ring-shaped material storage area is provided on the top of the feed tray 1015 for temporarily storing crude creatine monohydrate. The feed tray 1015 is sleeved on the stalk section 1010. An upper cover 1016 is installed on the top of the vertical cylinder 101, and the upper cover 1016 is detachably installed.

[0055] In another embodiment of the present invention, please refer to Figure 5 The inner ring of the installation kit 1012 cooperates with the flower shaft segment 1010, the outer ring of the installation kit 1012 is annular, and the installation kit 1012 and the separation plate 1013 are rotatably installed.

[0056] In another embodiment of the present invention, refer to Figure 6 and Figure 7 A side opening is provided on the side of the vertical cylinder 101 , and a side door 102 is hingedly installed at the side opening. The side door 102 is opened to take out the creatine monohydrate intermediate product from the filter cylinder 108 .

[0057] In another embodiment of the present invention, please refer to Figure 5 , and also includes a drying mechanism 4 and a crushing mechanism 5. The creatine monohydrate crystals produced by the recrystallization reactor 3 are dried by the drying mechanism 4 and crushed by the crushing mechanism 5 to produce the product creatine monohydrate.

[0058] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A synthetic device for producing creatine monohydrate, characterized in that: It comprises a pulping centrifugal integrated mechanism (1), a thermal dissolution mechanism (2), a recrystallization reactor (3), a liquid preparation tank (6) and an acid liquid conveying system (7); The supersaturated solution outlet of the thermal dissolution mechanism (2) is connected to the liquid inlet of the recrystallization reactor (3) through a pipeline, the mother liquid outlet of the recrystallization reactor (3) is connected to the liquid preparation tank (6) through a pipeline, the liquid preparation tank (6) is equipped with a pH detection component (8), the liquid outlet of the acid solution delivery system (7) is connected to the liquid preparation tank (6) through a pipeline, and the liquid outlet of the liquid preparation tank (6) is connected to the original liquid inlet of the thermal dissolution mechanism (2) through a pipeline; The integrated pulping and centrifugal mechanism (1) comprises a pulping component and a centrifugal dehydration component. The centrifugal dehydration component dehydrates the product of the pulping component. The creatine monohydrate intermediate product produced by the centrifugal dehydration component is transported to the thermal dissolution mechanism (2) for supersaturated solution preparation.

2. The synthetic device for producing creatine monohydrate according to claim 1, characterized in that: It also includes a mother liquid renewal system, which includes a waste liquid discharge system (10) and a new liquid replenishment system (9). The new liquid replenishment system (9) replenishes new mother liquid into the liquid preparation tank (6).

3. The synthetic device for producing creatine monohydrate as claimed in claim 1, characterized in that: The recrystallization reaction kettle (3) is provided in plurality, and the plurality of recrystallization reaction kettles (3) are incorporated between the thermal dissolution mechanism (2) and the liquid preparation tank (6).

4. The device for producing creatine monohydrate as claimed in claim 1, characterized in that: The integrated pulping and centrifugal mechanism (1) comprises A vertical cylinder (101), wherein the top end of the vertical cylinder (101) is open, the bottom end of the vertical cylinder (101) is recessed inward to form a protrusion (106), the outer side of the protrusion (106) and the inner side of the vertical cylinder (101) form an annular area (105), and the bottom of the vertical cylinder (101) is fixedly connected with a support leg (104); A liquid discharge port (103), wherein the liquid discharge port (103) is fixedly mounted on a side surface of the vertical cylinder (101), and the liquid discharge port (103) is in communication with the annular area (105); A driving motor (107), wherein the driving motor (107) is fixedly mounted at the bottom of the protruding portion (106) with its output shaft facing upward, and the output shaft of the driving motor (107) extends into the interior of the vertical cylinder (101); A filter cylinder (108), wherein the bottom of the filter cylinder (108) is fixedly connected to the top flange of the output shaft of the driving motor (107), a transmission shaft (109) is fixedly connected to the center of the inner bottom of the filter cylinder (108), and the top of the transmission shaft (109) has a flower shaft section (1010); A first grinding disc (1011), a separating disc (1013), a second grinding disc (1014) and a feeding disc (1015); the first grinding disc (1011) and the second grinding disc (1014) are both transmission-connected to the flower axis segment (1010); an overflow gap is provided at the connection between the first grinding disc (1011), the second grinding disc (1014) and the flower axis segment (1010); the separating disc (1013) is rotationally connected to the flower axis segment (1010) via an installation kit (1012); the separating disc (1013) is located between the first grinding disc (1011) and the second grinding disc (1014); the feeding disc (1015) is fixedly installed on the inner side of the vertical cylinder (101); the ends of the feeding disc (1015) and the separating disc (1013) are both provided with leakage holes; the separating disc (1013) is fixedly connected to the vertical cylinder (101).

5. The device for producing creatine monohydrate as claimed in claim 4, characterized in that: An annular material storage area is provided at the top of the feed tray (1015), the feed tray (1015) is sleeved on the flower axis section (1010), and an upper cover (1016) is installed at the top of the vertical cylinder (101).

6. The device for producing creatine monohydrate as claimed in claim 4, characterized in that: The inner ring of the installation kit (1012) cooperates with the flower shaft section (1010), the outer ring of the installation kit (1012) is annular, and the installation kit (1012) is rotatably installed with the separation plate (1013).

7. The device for producing creatine monohydrate as claimed in claim 4, characterized in that: A side opening is provided on the side of the vertical cylinder (101), and a side door (102) is hingedly installed at the side opening.

8. The device for producing creatine monohydrate as claimed in claim 4, characterized in that: The top of the first grinding disc (1011) and the bottom of the separation disc (1013) form a first grinding area, the top of the separation disc (1013) and the bottom of the second grinding disc (1014) form a second grinding area, and the top of the second grinding disc (1014) and the bottom of the feed disc (1015) form a third grinding area; The first grinding area and the third grinding area are both inclined toward the center of the flower axis segment (1010), and the second grinding area is inclined toward the outer contour of the separation plate (1013).

9. The device for producing and synthesizing creatine monohydrate according to claim 1, characterized in that: It also comprises a drying mechanism (4) and a crushing mechanism (5). The creatine monohydrate crystals produced by the recrystallization reactor (3) are dried by the drying mechanism (4) and crushed by the crushing mechanism (5) to produce the product creatine monohydrate.

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