Exosome purification kit
By designing fixing and limiting mechanisms in the kit, clamping and fixing the test tube, the problem of test tube shaking when the kit is carried is solved, and the stability of the kit and the safety of the test tube are improved.
Patent Information
- Application Number
- CN202421112760.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-21
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2034-05-21
AI Technical Summary
When carrying the kit, the internal test tube is easily shaken, causing damage to collide with the inner wall of the kit.
An exosome purification kit was designed, using a fixing mechanism and a limiting mechanism, including abutment plate, connecting column, clamp, L-shaped plate, screw, guide block, bevel gear and limiting plate and other components, through the driving shaft , the coordination of driving gears, driven gears, screws and guide blocks, clamping and fixing the test tubes, and the coupling plates of the test tubes are achieved by combining the limiting plates, sleeve plates, U-shaped round rods and sliders. and fixed.
It effectively avoids the test tube shaking during carrying, ensures that the test tube does not collide with the inner wall of the kit, and improves the stability and service life of the kit.
Smart Images
Figure CN222272764U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of kits, in particular to an exosome purification kit. Background Art
[0002] The test kit is a box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc. It is generally used in hospitals and pharmaceutical companies, while the exosome purification kit is a tool used to purify exosomes.
[0003] Currently, a test kit usually contains multiple test tubes containing reagents, and most of the test tubes are placed in a slot. When the test kit is carried, the test tubes inside are easily shaken, which can easily cause the test tubes to collide with the inner wall of the test kit and be damaged. Utility Model Content
[0004] In view of the above situation, in order to overcome the defects of the prior art, the utility model provides an exosome purification kit, which effectively solves the problem that the internal test tube of the current kit is easily shaken when being carried.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solution: an exosome purification kit, comprising a box body, a box cover hinged on the top of the box body, a handle fixedly installed on the box cover, and a fixing mechanism and a limiting mechanism installed inside the box body;
[0006] The fixing mechanism includes two abutment plates symmetrically fixed inside the box body, two connecting columns are symmetrically fixedly connected between the two abutment plates, two clamping plates are symmetrically arranged between the two abutment plates, and the two clamping plates are movably sleeved on the outer sides of the two connecting columns, an L-shaped plate is fixedly installed inside the box body, the L-shaped plate is located between the two clamping plates, a screw is rotatably connected inside the L-shaped plate, a screw sleeve is threadedly sleeved on the outer side of the screw, and two movable rods are symmetrically rotatably connected on the outer side of the screw sleeve, the ends of the two movable rods away from the screw sleeve are respectively rotatably connected to the bottom of the two clamping plates, a guide rod is fixedly installed inside the L-shaped plate, a guide block is movably sleeved on the outer side of the guide rod, and the guide block is fixed to the outer side of the screw sleeve.
[0007] Preferably, a driven shaft is rotatably connected inside the box body, a second bevel gear is fixedly mounted on one end of the driven shaft, a first bevel gear is fixedly mounted on the outside of the screw, and the first bevel gear is meshingly connected with the second bevel gear.
[0008] Preferably, a vertical plate is fixedly installed inside the box body, a driven shaft passes through the vertical plate and is rotatably connected to the vertical plate, a driving shaft is rotatably connected to the side of the vertical plate away from the screw, one end of the driving shaft away from the vertical plate extends to the outside of the box body and a turntable is fixedly installed, a driving gear is fixedly installed on the outside of the driving shaft, a driven gear is fixedly installed on the outside of the driven shaft, and the driven gear is meshingly connected to the driving gear.
[0009] Preferably, the limiting mechanism includes a limiting plate movably installed in the box body, the limiting plate is located above the two clamping plates, through holes are evenly spaced on both sides of the limiting plate, two sleeve plates are symmetrically fixedly installed inside the box body, the two sleeve plates are respectively fixedly sleeved on the outer sides of the two connecting columns, and the limiting plate is movably sleeved on the outer sides of the two sleeve plates.
[0010] Preferably, a U-shaped round rod is fixedly installed on the top of the limit plate, and two slides are symmetrically and movably sleeved on the outer side of the U-shaped round rod, a handle is fixedly installed on the side where the two slides are close to each other, and a plug rod is fixedly installed on the side where the two slides are away from each other, and holes are equidistantly provided on the side where the two sleeve plates are close to each other, and the two plug rods are respectively inserted into the two corresponding holes, and a top plate is fixedly installed on the top of the limit plate, the top plate is fixedly sleeved on the middle part of the outer side of the U-shaped round rod, the top plate is located between the two slides, and springs are fixedly connected between the two slides and the top plate, and the two springs are sleeved on the outer side of the U-shaped round rod.
[0011] Preferably, a slide groove is provided on the top of the limiting plate, and sliding blocks are fixedly installed on the bottom of the two sliding plates, and the two sliding blocks are slidably connected to the slide groove.
[0012] Compared with the prior art, the beneficial effects of the utility model are:
[0013] (1) The utility model facilitates the rotation of the driven shaft through the cooperation between the driving shaft and the driving gear and the driven gear, and facilitates the rotation of the screw through the cooperation between the bevel gear 2 and the bevel gear 1, and facilitates the sliding of the two clamping plates along the two connecting columns through the cooperation between the screw sleeve and the guide block and the guide rod and the movable rod, so that the clamping plates and the abutting plates can clamp and fix the test tube, thereby preventing the test tube from shaking when the box body is carried;
[0014] (2) The new type facilitates the lifting and lowering of the limit plate through the cooperation between the limit plate and the sleeve plate, and facilitates the sliding of the slide plate through the cooperation between the U-shaped round rod and the slide plate, and the slide block and the slide groove. Under the action of the spring force, the insertion rod can be inserted into the corresponding insertion hole, and the limit plate can be fixed to the two sleeve plates, so that the position of the limit plate can be adjusted according to the length of the test tube, so that the test tube can pass through the through hole, and the limit plate plays a role in limiting the test tube. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention.
[0016] In the attached picture:
[0017] Figure 1 This is a schematic diagram of the structure of the exosome purification kit of the utility model;
[0018] Figure 2 This is a schematic diagram of the cross-sectional structure of the box body of the utility model;
[0019] Figure 3 This is a schematic diagram of the fixing mechanism structure of the utility model;
[0020] Figure 4 This is a schematic diagram of the L-shaped plate structure of the utility model;
[0021] Figure 5 This is a schematic diagram of the structure of the limiting mechanism of the utility model;
[0022] In the figure: 1, box body; 2, fixing mechanism; 201, abutment plate; 202, connecting column; 203, L-shaped plate; 204, clamping plate; 205, guide block; 206, bevel gear 1; 207, bevel gear 2; 208, vertical plate; 209, driven gear; 2010, driven shaft; 2011, turntable; 2012, driving shaft; 2013, driving gear; 2014, screw sleeve; 2015, screw rod; 2016, movable rod; 2017, guide rod; 3, limit mechanism; 301, limit plate; 302, socket; 303, plug rod; 304, U-shaped round rod; 305, handle; 306, spring; 307, slider; 308, sleeve plate; 309, slide plate; 3010, slide groove; 3011, top plate; 3012, through hole; 4, box cover; 5, handle. DETAILED DESCRIPTION
[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.
[0024] Embodiment 1, by Figure 1-2 The utility model comprises a box body 1 , a box cover 4 is hinged on the top of the box body 1 , a handle 5 is fixedly installed on the box cover 4 , and a fixing mechanism 2 and a limiting mechanism 3 are installed inside the box body 1 .
[0025] Specifically, by Figure 3-4It is given that the fixing mechanism 2 includes two abutment plates 201 symmetrically fixed inside the box body 1, two connecting columns 202 are symmetrically fixedly connected between the two abutment plates 201, two clamping plates 204 are symmetrically arranged between the two abutment plates 201, and the two clamping plates 204 are movably sleeved on the outer sides of the two connecting columns 202, an L-shaped plate 203 is fixedly installed inside the box body 1, the L-shaped plate 203 is located between the two clamping plates 204, a screw rod 2015 is rotatably connected inside the L-shaped plate 203, a screw sleeve 2014 is threadedly sleeved on the outer side of the screw rod 2015, and two movable rods 2016 are symmetrically rotatably connected on the outer side of the screw sleeve 2014, and the ends of the two movable rods 2016 away from the screw sleeve 2014 are rotatably connected to the bottoms of the two clamping plates 204 respectively, a guide rod 2017 is fixedly installed inside the L-shaped plate 203, and a guide block 2017 is movably sleeved on the outer side of the guide rod 2017 5. The guide block 205 is fixed to the outside of the screw sleeve 2014. The driven shaft 2010 is rotatably connected inside the box body 1. A bevel gear 207 is fixedly installed on one end of the driven shaft 2010. A bevel gear 206 is fixedly installed on the outside of the screw 2015. The bevel gear 206 is meshingly connected with the bevel gear 207. A vertical plate 208 is fixedly installed inside the box body 1. The driven shaft 2010 passes through the vertical plate 208 and is rotatably connected with the vertical plate 208. The side of the vertical plate 208 away from the screw 2015 is rotatably connected with the driving shaft 2012. One end of the driving shaft 2012 away from the vertical plate 208 extends to the outside of the box body 1 and is fixedly installed with a turntable 2011. A driving gear 2013 is fixedly installed on the outside of the driving shaft 2012. A driven gear 209 is fixedly installed on the outside of the driven shaft 2010. The driven gear 209 is meshingly connected with the driving gear 2013.
[0026] When in use, first rotate the turntable 2011 to drive the driving shaft 2012 to rotate, and drive the driving gear 2013 to rotate. Since the driving gear 2013 is meshed and connected with the driven gear 209, the driven shaft 2010 is driven to rotate, and the bevel gear 207 is driven to rotate. Since the bevel gear 207 is meshed and connected with the bevel gear 1 206, the screw rod 2015 is driven to rotate. Since the guide block 205 is movably sleeved on the outer side of the guide rod 2017, it plays a role of limiting the screw sleeve 2014, so that the screw sleeve 2014 rises along the screw rod 2015, and then the two clamping plates 204 are driven to slide along the two connecting columns 202 by the two movable rods 2016 respectively. Finally, the test tube is clamped and fixed by the clamping plates 204 and the abutment plates 201 to prevent it from shaking.
[0027] Specifically, by Figure 5It is given that the limiting mechanism 3 includes a limiting plate 301 movably installed in the box body 1, the limiting plate 301 is located above the two clamping plates 204, and through holes 3012 are evenly spaced on both sides of the limiting plate 301. Two sleeve plates 308 are symmetrically fixedly installed inside the box body 1. The two sleeve plates 308 are respectively fixedly sleeved on the outsides of the two connecting columns 202. The limiting plate 301 is movably sleeved on the outsides of the two sleeve plates 308. A U-shaped round rod 304 is fixedly installed on the top of the limiting plate 301, and two slide plates 309 are symmetrically and movably sleeved on the outsides of the U-shaped round rod 304. The handles 305 are fixedly installed on the sides of the two slide plates 309 that are close to each other, and the handles 305 are fixedly installed on the sides of the two slide plates 309 that are away from each other. There is an insertion rod 303, and holes 302 are evenly spaced on the side where the two sleeve plates 308 are close to each other. The two insertion rods 303 are respectively inserted into the two corresponding holes 302. A top plate 3011 is fixedly installed on the top of the limiting plate 301. The top plate 3011 is fixedly sleeved on the middle part of the outer side of the U-shaped round rod 304. The top plate 3011 is located between the two slide plates 309. Springs 306 are fixedly connected between the two slide plates 309 and the top plate 3011. The two springs 306 are sleeved on the outer side of the U-shaped round rod 304. A sliding groove 3010 is provided on the top of the limiting plate 301, and sliders 307 are fixedly installed on the bottom of the two slide plates 309. The two sliders 307 are slidably connected to the sliding groove 3010.
[0028] When the handles 305 are in use, the two slide plates 309 are first pulled to slide along the U-shaped round rod 304. At the same time, the two slide blocks 307 slide along the slide groove 3010 to ensure the stability of the two slide plates 309 when moving, so that the two insertion rods 303 move away from each other until they are separated from the two sleeve plates 308 respectively. At this time, the two springs 306 are compressed, and then the limit plate 301 is slid along the two sleeve plates 308 to adjust the height. When the limit plate 301 has finished moving, the control of the two handles 305 is released. At this time, the two springs 306 are reset to drive the two slide plates 309 to move until the two insertion rods 303 are respectively inserted into the two corresponding sockets 302, and the limit plate 301 and the two sleeve plates 308 are fixed. Finally, the test tube is passed through the through hole 3012 to achieve the limitation of test tubes of different lengths.
Claims
1. An exosome purification kit, comprising a box body (1), characterized in that: The top of the box body (1) is hingedly connected with a box cover (4), a handle (5) is fixedly mounted on the box cover (4), and a fixing mechanism (2) and a limiting mechanism (3) are mounted inside the box body (1); The fixing mechanism (2) comprises two abutment plates (201) symmetrically fixed inside the box body (1), two connection pillars (202) are symmetrically fixedly connected between the two abutment plates (201), two clamping plates (204) are symmetrically arranged between the two abutment plates (201), the two clamping plates (204) are movably sleeved on the outsides of the two connection pillars (202), an L-shaped plate (203) is fixedly installed inside the box body (1), the L-shaped plate (203) is located between the two clamping plates (204), and a screw is rotatably connected inside the L-shaped plate (203). (2015), the outer side of the screw rod (2015) is threadedly sleeved with a screw sleeve (2014), the outer side of the screw sleeve (2014) is symmetrically rotatably connected with two movable rods (2016), one end of the two movable rods (2016) away from the screw sleeve (2014) is respectively rotatably connected to the bottom of the two clamping plates (204), a guide rod (2017) is fixedly installed in the L-shaped plate (203), the outer side of the guide rod (2017) is movably sleeved with a guide block (205), and the guide block (205) is fixed to the outer side of the screw sleeve (2014).
2. The exosome purification kit according to claim 1, characterized in that: The box body (1) is rotatably connected to a driven shaft (2010) inside, a bevel gear 2 (207) is fixedly mounted on one end of the driven shaft (2010), a bevel gear 1 (206) is fixedly mounted on the outside of the screw rod (2015), and the bevel gear 1 (206) is meshingly connected with the bevel gear 2 (207).
3. The exosome purification kit according to claim 1, characterized in that: A vertical plate (208) is fixedly installed inside the box body (1); a driven shaft (2010) passes through the vertical plate (208) and is rotatably connected to the vertical plate (208); a driving shaft (2012) is rotatably connected to a side of the vertical plate (208) away from the screw rod (2015); an end of the driving shaft (2012) away from the vertical plate (208) extends to the outside of the box body (1) and is fixedly installed with a turntable (2011); a driving gear (2013) is fixedly installed on the outside of the driving shaft (2012); a driven gear (209) is fixedly installed on the outside of the driven shaft (2010); and the driven gear (209) is meshingly connected with the driving gear (2013).
4. The exosome purification kit according to claim 1, characterized in that: The limiting mechanism (3) comprises a limiting plate (301) movably mounted in the box body (1), the limiting plate (301) being located above the two clamping plates (204), through holes (3012) being evenly spaced on both sides of the limiting plate (301), two sleeve plates (308) being symmetrically fixedly mounted inside the box body (1), the two sleeve plates (308) being fixedly sleeved on the outer sides of the two connecting columns (202) respectively, and the limiting plate (301) being movably sleeved on the outer sides of the two sleeve plates (308).
5. The exosome purification kit according to claim 4, characterized in that: A U-shaped round rod (304) is fixedly installed on the top of the limit plate (301), and two slide plates (309) are symmetrically and movably sleeved on the outer side of the U-shaped round rod (304). A handle (305) is fixedly installed on the side of the two slide plates (309) close to each other, and a plug rod (303) is fixedly installed on the side of the two slide plates (309) away from each other. Plug holes (302) are evenly spaced on the side of the two sleeve plates (308) close to each other. The two plug rods (30 3) are respectively inserted into two corresponding insertion holes (302), a top plate (3011) is fixedly installed on the top of the limit plate (301), the top plate (3011) is fixedly sleeved on the middle part of the outer side of the U-shaped round rod (304), the top plate (3011) is located between the two slide plates (309), springs (306) are fixedly connected between the two slide plates (309) and the top plate (3011), and the two springs (306) are sleeved on the outer side of the U-shaped round rod (304).
6. The exosome purification kit according to claim 4, characterized in that: A slide groove (3010) is provided on the top of the limiting plate (301), and sliding blocks (307) are fixedly installed on the bottoms of the two sliding plates (309), and the two sliding blocks (307) are slidably connected to the slide groove (3010).