Automatic liquid preparation system for chromosome harvesting instrument

By designing an automatic liquid distribution system of multi-pass rotary distribution valve and bubble sensor on a chromosome harvester, the problems of inaccurate solution mixing and difficulty in pipeline cleaning in the prior art are solved, and automatic and accurate quantification of reagents and pipelines are realized. Clean the reagent preparation quality in a timely manner.

CN222342731UActive Publication Date: 2025-01-14GUANGZHOU DAHUI BIOTECH CO LTD +1
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Patent Information

Application Number
CN202421176616.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-27
Publication Date
2025-01-14
Estimated Expiration
2034-05-27

AI Technical Summary

Technical Problem

The automatic liquid dispensing system of the existing chromosome harvester cannot mix the solution in proportion, which has difficulties in cleaning the pipeline and untimely detection of liquid deficiency, which affects the quality of reagent preparation.

Method used

An automatic liquid distribution system including injection module, liquid distribution barrel, multi-pass rotary distribution valve, bubble sensor and control system was designed. The solution was detected by the bubble sensor and stopped injection, so that the solution was mixed in proportion and used for distilled water. Pipe cleaning.

Benefits of technology

The automatic and accurate quantity preparation of reagents is realized, the risk of operational pollution is reduced, the liquid shortage is notified in a timely manner, and the pipeline is cleaned with distilled water to ensure that the reagent preparation meets the standards.

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Abstract

The utility model relates to the technical field of automatic liquid preparation, in particular to an automatic liquid preparation system for a chromosome harvesting instrument, which comprises an injection module, a liquid preparation barrel, at least two solvent storage tanks, a distilled water storage tank and a waste liquid barrel, the injection module comprises an injection pump, a liquid inlet of the injection pump is respectively connected with a solvent storage tank and a distilled water storage tank, and a liquid outlet of the injection pump is connected with a liquid preparation barrel and a waste liquid barrel through a multi-way pipeline. And a bubble sensor is also arranged between the injection pump and the solvent storage tank. According to the utility model, at least two solutions can be mixed according to different proportions, and meanwhile, the liquid shortage condition of the solvent can be detected through the bubble sensor, so that the solution can be supplemented in time; and a distilled water storage tank is introduced to realize a pipeline cleaning function.
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Description

Technical Field

[0001] The utility model relates to the technical field of automatic liquid preparation, in particular to an automatic liquid preparation system for a chromosome harvester. Background Art

[0002] Currently, the reagents used in the chromosome harvesting process need to be prepared manually by the user. Since the solutions required for preparing the reagents are volatile and have a pungent odor, they can easily cause harm to the human body. During manual preparation, the amount of solution drawn by the syringe may not be accurate, which will affect subsequent experiments, and there is a risk of contaminating the reagents due to improper operation.

[0003] The Chinese utility model patent with the authorization announcement number CN214629460U and the authorization announcement date of November 9, 2021, discloses a device for automatically preparing cell freezing solution, including a rack, an injection module, one or more injection containers, one or more cryoprotectant containers and one or more injection pumps; the injection module includes one or more injection ports; the injection module, the injection container and the injection pump are all arranged on the rack; the injection pump is connected to the cryoprotectant container at one end of the pipeline and the injection port at the other end. This solution can realize the quantitative preparation of freezing solution, but it cannot achieve the mixing of solutions in proportion. At the same time, there are problems such as the trouble of cleaning the pipeline, and the inability to timely detect the lack of liquid that leads to the substandard preparation of reagents. Utility Model Content

[0004] In order to overcome the problems existing in the prior art, the utility model aims to provide an automatic liquid preparation system for a chromosome harvester, which can mix two solutions in different proportions, detect the lack of solution through a bubble sensor, and prepare the solution. In terms of system maintenance, a pipeline cleaning function is added.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an automatic liquid preparation system for a chromosome harvester, comprising an injection module, a liquid preparation barrel and at least two solvent storage tanks; the injection module comprises an injection pump, the liquid inlet of the injection pump is respectively connected to the solvent storage tank, and the liquid outlet of the injection pump is connected to the liquid preparation barrel; the injection pump comprises a distribution valve, and the solvent storage tank and the liquid preparation barrel are respectively connected to the port of the distribution valve.

[0006] The utility model is further configured as follows: the distribution valve is a multi-way rotary distribution valve.

[0007] The utility model is further configured as follows: the injection module also includes a control system, and the injection pump is electrically connected to the control system.

[0008] The utility model is further configured as follows: the automatic liquid dispensing system also includes a distilled water storage tank, and the distilled water storage tank is connected to the port of the distribution valve.

[0009] The utility model is further configured as follows: the automatic liquid dispensing system further comprises a waste liquid barrel, and the waste liquid barrel is connected to the port of the dispensing valve.

[0010] The utility model is further configured as follows: the automatic liquid dispensing system also includes a bubble sensor, and the bubble sensor is arranged on the connecting pipeline between the solvent storage tank and the injection pump.

[0011] The utility model is further configured that: the bubble sensor is electrically connected to the control system. During the injection process, if the solvent storage tank is short of liquid, bubbles will be present in the pipeline. After the bubble sensor detects the bubbles, the control system stops the injection and reminds the operator to replenish the liquid.

[0012] The beneficial effects of the above technical solution of the utility model are as follows:

[0013] 1. The utility model can automatically prepare reagents without the operator having to contact reagents that are volatile and have pungent odors and are likely to cause harm to the human body. The syringe pump is used to accurately and quantitatively prepare and mix two solutions, thereby reducing pollution problems caused by improper operation during the preparation process.

[0014] 2. The utility model sets a bubble sensor between the injection pump and the solution storage tank. When the solution storage tank is short of liquid, bubbles will exist in the pipeline. After the bubble sensor detects the bubbles, it can promptly notify the operator to replenish the liquid.

[0015] 3. The injection pump of the utility model is also connected to the distilled water cleaning pipeline. When discharging and cleaning, the injection pump will inject bubbles and distilled water into the waste liquid barrel to prevent the residual solution or bubbles in the pipeline from affecting the reagent preparation. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0017] Figure 1 This is a schematic diagram of the structure of the automatic liquid dispensing system of the utility model.

[0018] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0019] 1. Injection pump, 2. Solvent storage tank A, 3. Solvent storage tank B, 4. Distilled water storage tank, 5. Bubble sensor, 6. Liquid preparation barrel, 7. Waste liquid barrel. DETAILED DESCRIPTION

[0020] In order to enable those skilled in the art to better understand the technical solution of the present invention, the following is a clear and complete description of the technical solution of the present invention in conjunction with the drawings of the present invention. Based on the embodiments of the present invention, other similar embodiments obtained by ordinary technicians in the field without creative work should all fall within the scope of protection of the present invention. In addition, the directional words mentioned in the following embodiments, such as "up", "down", "left", "right", etc., are only referenced to the directions of the drawings. Therefore, the directional words used are used to illustrate rather than limit the creation of the present invention.

[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

[0022] The utility model is further described below in conjunction with the accompanying drawings and preferred embodiments.

[0023] Example:

[0024] like Figure 1 As shown, a preferred embodiment of the utility model is an automatic liquid preparation system for a chromosome harvester, comprising an injection module, a liquid preparation barrel 6 and at least two solvent storage tanks; the injection module comprises an injection pump 1, the liquid inlet of the injection pump 1 is respectively connected to the solvent storage tanks, and the liquid outlet of the injection pump 1 is connected to the liquid preparation barrel 6.

[0025] In this embodiment, two solvent storage tanks are used, including solvent storage tank A2 and solvent storage tank B3. Bubble sensors 5 are also provided on the connection pipelines between solvent storage tank A2 and solvent storage tank B3 and the injection pump 1. The automatic liquid dispensing system also includes a distilled water storage tank 4 and a waste liquid bucket 7 for pipeline cleaning.

[0026] The injection pump 1 includes a distribution valve, which is a multi-way rotary distribution valve including multiple ports; the solvent storage tank A2, the solvent storage tank B3, the liquid preparation barrel 6, the distilled water storage tank 4 and the waste liquid barrel 7 are respectively connected to the ports of the distribution valve. The injection module also includes a control system, and the injection pump 1 and the bubble sensor 5 are respectively electrically connected to the control system.

[0027] During actual operation, the control system controls the internal rotation of the distribution valve to connect the channels of the solvent storage tank A2, the injection pump and the liquid preparation barrel 6, and the injection pump 1 injects the solution of the solvent storage tank A2 into the liquid preparation barrel 6 according to the preset ratio; after completion, the control system controls the distribution valve to switch the connecting pipeline to connect the solvent storage tank B3 with the injection pump 1; according to the above steps, the solution of the solvent storage tank B3 is injected into the liquid preparation barrel 6 to complete the automatic preparation of the reagent.

[0028] During the injection process, the solvent storage tank is short of liquid, resulting in bubbles in the pipeline. After the bubble sensor 5 detects the bubbles, the control system stops the injection and reminds the operator to replenish the liquid.

[0029] The utility model can also realize the pipeline cleaning function, that is, after the liquid preparation is completed, the control system controls the distribution valve to switch the connecting pipeline, so that the channels of the distilled water storage tank 4 and the waste liquid barrel 7 are connected; the injection pump 1 is started to inject the residual liquid or bubbles into the waste liquid barrel 7 through distilled water.

[0030] Finally, it should be noted that the above-mentioned embodiments only express one or several implementation methods of the utility model, and the description is relatively specific and detailed, but it cannot be understood as limiting the scope of the utility model patent. It should be pointed out that for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the utility model, which all belong to the protection scope of the utility model. Therefore, the protection scope of the utility model patent shall be based on the attached claims.

Claims

1. An automatic liquid preparation system for a chromosome harvester, characterized in that: It includes an injection module, a liquid preparation barrel and at least two solvent storage tanks; the injection module includes an injection pump, the liquid inlet of the injection pump is respectively connected to the solvent storage tank, and the liquid outlet of the injection pump is connected to the liquid preparation barrel; the injection pump includes a distribution valve, and the solvent storage tank and the liquid preparation barrel are respectively connected to the port of the distribution valve.

2. The automatic liquid preparation system for a chromosome harvester according to claim 1, characterized in that: The distribution valve is a multi-way rotary distribution valve.

3. The automatic liquid preparation system for a chromosome harvester according to claim 1, characterized in that: The injection module also includes a control system, and the injection pump is electrically connected to the control system.

4. The automatic liquid preparation system for a chromosome harvester according to claim 3, characterized in that: The automatic liquid dispensing system further comprises a distilled water storage tank, which is connected to a port of the dispensing valve.

5. The automatic liquid preparation system for a chromosome harvester according to claim 3, characterized in that: The automatic liquid dispensing system further comprises a waste liquid barrel, which is connected to the port of the dispensing valve.

6. The automatic liquid preparation system for a chromosome harvester according to claim 3, characterized in that: The automatic liquid dispensing system further comprises a bubble sensor, which is arranged on a connecting pipeline between the solvent storage tank and the injection pump.

7. The automatic liquid preparation system for a chromosome harvester according to claim 6, characterized in that: The bubble sensor is electrically connected to the control system.

Citation Information

Patent Citations

  • Device for automatically preparing cell refrigerating fluid

    CN214629460U