Freeze-drying mold assembly for acellular matrix material
By adopting a combination design of worm, lifting component and locking component in the lyophilized mold of decellularized matrix material, the existing mold operation is complicated and bolt-slide problems are solved, and a stable and simple clamping effect is achieved to prevent material deformation.
Patent Information
- Application Number
- CN202420852091.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-23
- Publication Date
- 2025-02-07
- Estimated Expiration
- 2034-04-23
AI Technical Summary
The existing lyophilized decellular matrix material lyophilized molds are cumbersome during the fixing process, and bolt slips may occur after long-term use, which affects the stable clamping effect.
A lyophilized mold assembly of decellularized matrix material is designed, using a worm and a lifting assembly to cooperate with the locking assembly. Through the rotation of the worm, the second clamp slides along the first support, adjusts its height, and uses the locking assembly to prevent the worm from rotating, so as to realize Stable clamping.
The operation is simplified, the bolt slip phenomenon is avoided, the stable clamping effect is maintained, the decellularized matrix material is prevented, and the locking effect is improved.
Smart Images

Figure CN222438450U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of decellularized freeze-drying, in particular to a decellularized matrix material freeze-drying mold component. Background Art
[0002] Decellularized matrix materials are basic scaffold materials in the field of tissue engineering and regenerative medicine. This material retains its complete three-dimensional structure and has appropriate pore size, porosity, and adsorption. When used as an implant material, it can actively induce and promote the adhesion and ingrowth of surrounding cells and has good biocompatibility.
[0003] The freeze-drying mold for decellularized matrix materials is a special mold for preparing freeze-dried products of decellularized matrix materials. However, when fixing the freeze-drying mold for decellularized matrix materials, it is necessary to repeatedly turn the bolts to fix the base plate and the pressure plate together. Although this connection method ensures the stability of the connection, the operation is cumbersome, and the bolts may slip after long-term use. For this reason, we propose a freeze-drying mold assembly for decellularized matrix materials. Utility Model Content
[0004] The purpose of the utility model is to provide a freeze-drying mold assembly for decellularized matrix materials to solve the problems raised by the above-mentioned background technology.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a decellularized matrix material freeze-drying mold assembly, comprising a first splint, the first splint is slidably connected to a second splint, the second splint is slidably connected to a first support member, the first support member is connected to both ends of the first splint, the second splint is connected to a worm through a lifting assembly, one end of the worm is rotatably connected to the first support member, and the worm can be locked using a locking assembly.
[0006] Preferably, the locking assembly includes an external spline, a spring, a second support member and an internal spline. The end of the worm gear away from the first support member is slidably connected to the external spline. The external spline is inserted into the outer sleeve of one end of the worm gear and the spring is arranged. The upper end of the external spline can be inserted into the second support member. The second support member is provided with the internal spline meshing with the external spline, and the external spline can be unlocked by an adjusting member.
[0007] Preferably, the adjusting member includes a first knob and a second knob, the first knob is installed at the top end of the external spline, and the top end of the first knob is rotatably connected to the second knob.
[0008] Preferably, the lifting assembly includes a worm wheel and a rack, the worm is meshed with the worm wheel, the worm wheel is rotatably connected to the first support member, and its side away from the worm is meshed with the rack, and the rack penetrates the first support member and is connected to the second clamping plate.
[0009] Preferably, two groups of first sliding rods are symmetrically mounted on the upper surface of the second clamping plate, and the first sliding rods penetrate the first supporting member and are slidably connected thereto.
[0010] Preferably, the first clamping plate is installed with four groups of second sliding rods, and the four groups of second sliding rods all pass through the second clamping plate and are slidably connected thereto.
[0011] Compared with the prior art, the beneficial effects of the utility model are:
[0012] 1. The utility model utilizes the rotation of the worm and cooperates with the lifting component to drive the second clamping plate to slide along the first support member, and adjusts its height so that it cooperates with the first clamping plate to clamp and press the decellularized matrix material, so that the decellularized matrix material is not easily deformed. At the same time, the locking component can be used to lock the worm to prevent it from rotating, thereby achieving stable clamping of the decellularized matrix material. Compared with the existing technology, the utility model is simple to use, is not prone to thread slippage, can maintain a stable clamping effect, and prevents the decellularized matrix material from deformation.
[0013] 2. The utility model drives the first knob and the outer spline to move by pressing the second knob, so that the outer spline is inserted into the worm and disengaged from the inner spline, and the spring is compressed at the same time. At this time, turning the first knob can drive the outer spline and the worm to rotate, which can drive the worm wheel to rotate, so that the rack moves accordingly, and the second clamping plate can be driven to rise and fall to adjust its height from the first clamping plate. Conversely, the second knob is released, the spring is reset, and the outer spline is pushed to rise and inserted into the inner spline. The second support member is used to limit the outer spline to prevent it from rotating, thereby locking the worm. In combination with the self-locking effect of the worm wheel and the worm, the locking effect can be improved to maintain the stability of the clamping of the decellularized matrix material.
[0014] 3. When the second clamping plate of the utility model is lifted or lowered, the first slide bar can be driven to slide and lift along the first support member, and the second clamping plate can slide and lift along the second slide bar, which helps to improve the stability of the second clamping plate when it is lifted or lowered. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 It is a cross-sectional view of the overall structure of the utility model;
[0016] Figure 2 It is an enlarged view of structure A of the utility model;
[0017] Figure 3It is a schematic diagram of the overall structure of the utility model;
[0018] Figure 4 It is an exploded view of the overall structure of the utility model.
[0019] In the figure: 1, first clamping plate, 2, second clamping plate, 3, first supporting member, 4, worm, 5, external spline, 6, spring, 7, second supporting member, 8, internal spline, 9, first knob, 10, second knob, 11, worm wheel, 12, rack, 13, first slide bar, 14, second slide bar. DETAILED DESCRIPTION
[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0021] Embodiment 1
[0022] Please refer to Figure 1-4 As shown, the utility model provides a decellularized matrix material freeze-drying mold assembly, including a first splint 1, the first splint 1 is slidably connected to a second splint 2, the second splint 2 is slidably connected to a first support member 3, the first support member 3 is connected to both ends of the first splint 1, the second splint 2 is connected to a worm 4 through a lifting assembly, one end of the worm 4 is rotatably connected to the first support member 3, and the worm 4 can be locked using a locking assembly.
[0023] In this embodiment, the rotation of the worm 4 and the lifting assembly can drive the second clamping plate 2 to slide along the first support member 3, and adjust its height so that it can cooperate with the first clamping plate 1 to clamp and press the decellularized matrix material, so that the decellularized matrix material is not easily deformed. At the same time, the locking assembly can be used to lock the worm 4 to prevent it from rotating, thereby achieving stable clamping of the decellularized matrix material. Compared with the existing technology, it is simple to use, less prone to thread slippage, and can maintain a stable clamping effect to prevent the decellularized matrix material from deformation.
[0024] Please refer to Figure 1-4As shown, the locking assembly includes an external spline 5, a spring 6, a second support member 7 and an internal spline 8. The end of the worm 4 away from the first support member 3 is slidably connected to the external spline 5. The external spline 5 is inserted into the external sleeve spring 6 at one end of the worm 4. The upper end of the external spline 5 can be inserted into the second support member 7. The second support member 7 is provided with an internal spline 8 meshing with the external spline 5. The external spline 5 can be unlocked by an adjusting member. The adjusting member includes a first knob 9 and a second knob 10. The first knob 9 is installed on the top of the external spline 5, and the top of the first knob 9 is rotatably connected to the second knob 10. The lifting assembly includes a worm wheel 11 and a rack 12. The worm 4 is meshed with the worm wheel 11, and the worm wheel 11 is rotatably connected to the first support member 3, and its side away from the worm 4 is meshed with the rack 12. The rack 12 penetrates the first support member 3 and is connected to the second clamping plate 2.
[0025] In this embodiment, by pressing the second knob 10, the first knob 9 and the external spline 5 are driven to move, so that the external spline 5 is inserted into the worm 4 and disengaged from the internal spline 8, and the spring 6 is compressed at the same time. At this time, rotating the first knob 9 can drive the external spline 5 and the worm 4 to rotate, which can drive the worm wheel 11 to rotate, so that the rack 12 moves accordingly, and the second clamping plate 2 can be driven to rise and fall, and its height from the first clamping plate 1 is adjusted. Conversely, the second knob 10 is released, the spring 6 is reset, and the external spline 5 is pushed to rise and insert the internal spline 8, and the second support member 7 is used to limit the external spline 5 to prevent it from rotating, thereby locking the worm 4. In combination with the self-locking effect of the worm wheel 11 and the worm 4, the locking effect can be improved to maintain the stability of the clamping of the decellularized matrix material.
[0026] Please refer to Figure 1-4 As shown, two groups of first slide bars 13 are symmetrically installed on the upper surface of the second clamping plate 2, the first slide bars 13 penetrate the first support member 3 and are slidably connected thereto, and the first clamping plate 1 is installed with four groups of second slide bars 14, the four groups of second slide bars 14 all pass through the second clamping plate 2 and are slidably connected thereto.
[0027] In this embodiment, when the second clamping plate 2 is raised or lowered, the first slide bar 13 can be driven to slide and rise along the first support member 3 , and the second clamping plate 2 can slide and rise along the second slide bar 14 , which helps to improve the stability of the second clamping plate 2 when it is raised or lowered.
[0028] Working principle: First, by pressing the second knob 10, the first knob 9 and the outer spline 5 are driven to move, so that the outer spline 5 is inserted into the worm 4 and disengaged from the inner spline 8, and the spring 6 is compressed at the same time. At this time, turning the first knob 9 can drive the outer spline 5 and the worm 4 to rotate, which can drive the worm wheel 11 to rotate, so that the rack 12 moves accordingly, and the second clamping plate 2 can be driven to rise and fall to adjust its height from the first clamping plate 1. Conversely, the second knob 10 is released, the spring 6 is reset, and the outer spline 5 is pushed to rise and insert the inner spline 8, and the second support member 7 is cooperated to limit the outer spline 5 to prevent it from rotating, thereby locking the worm 4. In combination with the self-locking effect of the worm wheel 11 and the worm 4, the locking effect can be improved to maintain the stability of the acellular matrix material clamping. When the second clamping plate 2 is lifted or lowered, the first sliding bar 13 can be driven to slide and lift along the first supporting member 3, and the second clamping plate 2 can slide and lift along the second sliding bar 14, which helps to improve the stability of the second clamping plate 2 when it is lifted or lowered.
[0029] The contents not described in detail in this specification belong to the prior art known to professionals in this field.
[0030] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art may still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.
Claims
1. A freeze-drying mold assembly for a cell-free matrix material, comprising a first clamping plate (1), characterized in that: The first clamping plate (1) is slidably connected to the second clamping plate (2), the second clamping plate (2) is slidably connected to the first support member (3), the first support member (3) is connected to both ends of the first clamping plate (1), the second clamping plate (2) is connected to the worm (4) through a lifting component, one end of the worm (4) is rotatably connected to the first support member (3), and the worm (4) can be locked by using a locking component.
2. The freeze-drying mold assembly for decellularized matrix material according to claim 1, characterized in that: The locking assembly comprises an external spline (5), a spring (6), a second support member (7) and an internal spline (8); one end of the worm (4) away from the first support member (3) is slidably connected to the external spline (5); the external spline (5) is inserted into the outer side of one end of the worm (4) and sleeved with the spring (6); the upper end of the external spline (5) can be inserted into the second support member (7); the second support member (7) is provided with the internal spline (8) meshing with the external spline (5); and the external spline (5) can be unlocked by an adjusting member.
3. The freeze-drying mold assembly for decellularized matrix material according to claim 2, characterized in that: The adjusting member comprises a first knob (9) and a second knob (10); the first knob (9) is installed at the top end of the external spline (5); and the top end of the first knob (9) is rotatably connected to the second knob (10).
4. The freeze-drying mold assembly for decellularized matrix material according to claim 1, characterized in that: The lifting assembly comprises a worm wheel (11) and a rack (12), the worm (4) is meshed with the worm wheel (11), the worm wheel (11) is rotationally connected to the first support member (3), and the side away from the worm (4) is meshed with the rack (12), and the rack (12) penetrates the first support member (3) and is connected to the second clamping plate (2).
5. The freeze-drying mold assembly for decellularized matrix material according to claim 1, characterized in that: Two groups of first sliding rods (13) are symmetrically mounted on the upper surface of the second clamping plate (2); the first sliding rods (13) penetrate the first supporting member (3) and are slidably connected thereto.
6. The freeze-drying mold assembly for decellularized matrix material according to claim 1, characterized in that: The first clamping plate (1) is equipped with four groups of second sliding rods (14), and the four groups of second sliding rods (14) all pass through the second clamping plate (2) and are slidably connected thereto.