Filtering device for stem cell separation and extraction

Abstract

The utility model discloses a filtering device for stem cell separation and extraction, which belongs to the technical field of stem cell separation and comprises a base, a support is arranged above the base, a filtering box is arranged in the middle of the support, a convenient disassembly and assembly component is arranged below the filtering box, and a connecting seat is arranged below the convenient disassembly and assembly component. A connecting seat is arranged on the upper portion of the base, a collecting barrel is arranged below the connecting seat, a placing plate is arranged below the collecting barrel, an abutting spring is arranged below the placing plate, and a clamping assembly is arranged on one side of the placing plate. According to the device, the clamping seat, the clamping rod, the clamping block, the clamping sliding block, the clamping spring and the stable sliding rod are arranged, so that after the placing plate moves downwards, the placing plate is clamped and fixed, and the placing plate is prevented from rising back.

Description

Technical Field

[0001] The utility model belongs to the technical field of stem cell separation, and in particular relates to a filtering device for stem cell separation and extraction. Background Art

[0002] Stem cells are a type of cell with the potential for self-renewal and differentiation. Different separation methods are required for stem cell extraction depending on the cell type and tissue material. For example, neural stem cells are usually isolated by natural screening using serum-free culture medium, flow cytometry sorting, or immunomagnetic bead sorting. Filtration operations are often required when isolating and extracting stem cells.

[0003] Chinese patent application No. 202321246296.6 discloses a filtration device for stem cell separation and extraction, including a mounting frame, a filter box is mounted on the mounting frame, an electric telescopic rod is arranged at the top of the filter box, the output end of the electric telescopic rod extends to the inside of the filter box and is connected with a piston, the piston is slidably connected to the inner wall of the filter box, the bottom end of the filter box is threadedly connected with a connecting seat, and the inner wall of the connecting seat is provided with a filter screen; a collection bucket is arranged at the middle of the top of the mounting frame, a mounting seat is arranged at the top of the collection bucket, a connecting part is arranged at the top of the mounting seat, and the connection between the mounting seat and the collection bucket and the connecting part is provided with through holes, the top of the connecting part is abutted with the bottom of the connecting seat, and two sets of sealing plates are symmetrically slidably connected inside the mounting seat. The utility model avoids the waste of materials to be filtered, is easy to disassemble and assemble, and is more thoroughly cleaned, and effectively avoids external interference factors from polluting the filtered materials, thereby improving the filtering efficiency.

[0004] The above-mentioned disclosed patent, 1. When in use, the connection seat is removed through a threaded connection to facilitate subsequent cleaning work, but the connection seat is not convenient to disassemble and assemble when in use, and the convenience is not high enough; 2. When in use, the collection bucket is removed by compressing the spring through the placement plate, but when pressing down the placement plate, it is inconvenient to limit and fix the placement plate, and it needs to be pressed all the time, which makes it inconvenient for the staff to remove the collection bucket. Utility Model Content

[0005] To solve the problems raised in the above background technology, the utility model provides a filtration device for stem cell separation and extraction, which is convenient for disassembly and assembly of the connection seat to facilitate subsequent cleaning work, improves the convenience of use, and is convenient for limiting and fixing the placement plate after the placement plate moves down to prevent the limit plate from rebounding.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a filtering device for separation and extraction of stem cells, comprising a base, a bracket is arranged above the base, a filter box is arranged in the middle of the bracket, a convenient disassembly and assembly component is arranged below the filter box, a connecting seat is arranged below the convenient disassembly and assembly component, a collecting bucket is arranged below the connecting seat, a placing plate is arranged below the collecting bucket, an abutting spring is arranged below the placing plate, and a clamping component is arranged on one side of the placing plate.

[0007] Preferably, the convenient disassembly and assembly component includes a mounting seat 1, a mounting seat 2, a square plug rod, a fixed block, a pull rod, a fixed slider and a fixed spring, wherein a mounting seat 1 is arranged below the filter box, a mounting seat 2 is arranged below the mounting seat 1, and the mounting seat 1 and the mounting seat 2 are abutted against each other, a square plug rod is inserted above the mounting seat 2, and the top of the square plug rod is fixed to the mounting seat 1, a fixed block is arranged on one side of the square plug rod, a pull rod is arranged at one end of the fixed block, a fixed slider is arranged above the pull rod, and a fixed spring is arranged on one side of the fixed slider.

[0008] Preferably, a limit rod is arranged below the pull rod, a limit slider is arranged on one side of the limit rod, and a limit spring is arranged below the limit slider.

[0009] Preferably, a ball is provided at one end of the limit rod, and a fixing hole matching the fixing block is opened on one side of the square plug rod.

[0010] Preferably, one end of the fixed sliding block is slidably connected to a guide sliding rod, and a limiting hole cooperating with the limiting rod is provided below the pull rod.

[0011] Preferably, the clamping assembly includes a clamping seat, a clamping rod, a clamping block, a clamping slide, a clamping spring and a stabilizing slide bar, wherein a clamping seat is provided on one side of the placement plate, a clamping rod is provided inside the clamping seat, a clamping block is provided at one end of the clamping rod, a clamping slide bar is provided below the clamping rod, a clamping spring is provided on one side of the clamping slide bar, and one end of the clamping slide bar is slidably connected to the stabilizing slide bar.

[0012] Preferably, a guide slide is provided at one end of the clamping block, and a clamping hole matching the clamping block is provided at one side of the placement plate.

[0013] Preferably, damping telescopic rods are provided on both sides below the placement plate, and one end of the damping telescopic rod is fixedly connected to the placement plate, and the other end of the damping telescopic rod is fixedly connected to the base.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] 1. The utility model realizes convenient disassembly and assembly of the connecting seat by setting up a convenient disassembly and assembly component, which is convenient for subsequent cleaning work and improves the convenience of use. The first mounting seat, the second mounting seat, the square plug rod, the fixing block, the pull rod, the fixing slide block and the fixing spring are provided, so that the connecting seat and the filter box can be conveniently disassembled and assembled to facilitate subsequent cleaning work and improve the convenience of use. The limit rod, the limit slide block and the limit rebound are provided to prevent the pull rod from rebounding after being pulled out.

[0016] 2. The utility model sets a clamping assembly to limit and fix the placement plate after the placement plate is moved down to prevent the limit plate from rebounding. A clamping seat, a clamping rod, a clamping block, a clamping slider, a clamping spring and a stabilizing slide bar are provided to clamp and fix the placement plate after the placement plate is moved down to prevent it from rising back. A damping telescopic rod is provided to facilitate the slow and stable return of the placement plate. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 It is a schematic diagram of the structure of the utility model cut from the front view;

[0019] Figure 3 This is a schematic diagram of the structure of the convenient disassembly and assembly components of the utility model;

[0020] Figure 4 It is a structural schematic diagram of the clamping assembly of the utility model.

[0021] In the figure: 1. base; 2. bracket; 3. filter box; 4. convenient disassembly and assembly component; 41. mounting seat 1; 42. mounting seat 2; 43. square plug rod; 44. fixing block; 45. pull rod; 46. fixing slider; 47. fixing spring; 451. limit rod; 452. limit slider; 453. limit spring; 454. ball; 5. connecting seat; 6. collecting bucket; 7. placing plate; 8. abutment spring; 9. clamping assembly; 91. clamping seat; 92. clamping rod; 93. clamping block; 94. clamping slider; 95. clamping spring; 96. stabilizing slide bar; 97. damping telescopic rod. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] Example 1

[0024] See also Figure 1-4 The utility model provides the following technical solutions: a filtering device for separation and extraction of stem cells, comprising a base 1, a bracket 2 is arranged above the base 1, a filter box 3 is arranged in the middle of the bracket 2, a convenient disassembly and assembly component 4 is arranged below the filter box 3, a connecting seat 5 is arranged below the convenient disassembly and assembly component 4, a collecting bucket 6 is arranged below the connecting seat 5, a placing plate 7 is arranged below the collecting bucket 6, an abutting spring 8 is arranged below the placing plate 7, and a clamping component 9 is arranged on one side of the placing plate 7.

[0025] Specifically, the convenient disassembly and assembly component 4 includes a mounting seat 1 41, a mounting seat 2 42, a square plug rod 43, a fixing block 44, a pull rod 45, a fixing slide block 46 and a fixing spring 47, wherein a mounting seat 1 41 is arranged below the filter box 3, a mounting seat 2 42 is arranged below the mounting seat 1 41, and the mounting seat 1 41 and the mounting seat 2 42 are abutted against each other, a square plug rod 43 is inserted above the mounting seat 2 42, and the top of the square plug rod 43 and the mounting seat 1 41 are fixed, a fixing block 44 is arranged on one side of the square plug rod 43, a pull rod 45 is arranged at one end of the fixing block 44, a fixing slide block 46 is arranged above the pull rod 45, and a fixing spring 47 is arranged on one side of the fixing slide block 46.

[0026] By adopting the above technical solution, the pull rod 45 is pulled, and the pull rod 45 drives the fixed slider 46 to move and compress the fixed spring 47, so that the fixed block 44 is disengaged from the fixed hole. When the pull rod 45 moves to the limit hole and coincides with the limit rod 451, the limit spring 453 is reset, driving the limit rod 451 to insert into the limit hole, limiting and fixing the pull rod 45 to prevent it from rebounding. Then the connecting seat 5 can be removed for subsequent cleaning work, so that the device can be easily disassembled and assembled for the connecting seat 5 when in use, thereby improving the convenience of use.

[0027] Specifically, a limit rod 451 is disposed below the pull rod 45 , a limit slider 452 is disposed on one side of the limit rod 451 , and a limit spring 453 is disposed below the limit slider 452 .

[0028] By adopting the above technical solution, the limiting rod 451 is driven by the limiting spring 453 to be inserted into the limiting hole, so as to limit and fix the pull rod 45 to prevent it from rebounding when being pulled out.

[0029] Specifically, a ball 454 is disposed at one end of the limiting rod 451 , and a fixing hole matching the fixing block 44 is opened at one side of the square insert rod 43 .

[0030] By adopting the above technical solution, the ball 454 facilitates smooth sliding between the limit rod 451 and the pull rod 45 , and the fixing hole facilitates the insertion of the fixing block 44 to fix the square plug rod 43 .

[0031] Specifically, one end of the fixed sliding block 46 is slidably connected to a guide sliding rod, and a limiting hole matching the limiting rod 451 is provided below the pull rod 45 .

[0032] By adopting the above technical solution, the guide slide bar facilitates the stable sliding of the fixed slide block 46, and the limiting hole facilitates the insertion of the limiting rod 451, which limits and fixes the pull rod 45 to prevent it from rebounding.

[0033] When this embodiment is in use: pull the pull rod 45, the pull rod 45 drives the fixed slider 46 to move and compress the fixed spring 47, so that the fixed block 44 disengages from the fixed hole. When the pull rod 45 moves to the limit hole and coincides with the limit rod 451, the limit spring 453 resets, drives the limit rod 451 to insert into the limit hole, limits and fixes the pull rod 45 to prevent it from rebounding, and then the connecting seat 5 can be removed for subsequent cleaning. The ball 454 facilitates smooth sliding between the limit rod 451 and the pull rod 45, so that when the device is in use, it is convenient to disassemble and assemble the connecting seat 5, thereby improving the convenience of use.

[0034] Example 2

[0035] The present embodiment is different from the embodiment 1 in that: specifically, the clamping assembly 9 includes a clamping seat 91, a clamping rod 92, a clamping block 93, a clamping slide 94, a clamping spring 95 and a stabilizing slide bar 96, wherein a clamping seat 91 is provided on one side of the placement plate 7, a clamping rod 92 is provided inside the clamping seat 91, a clamping block 93 is provided at one end of the clamping rod 92, a clamping slide bar 94 is provided below the clamping rod 92, a clamping spring 95 is provided on one side of the clamping slide bar 94, and a stabilizing slide bar 96 is slidably connected to one end of the clamping slide bar 94.

[0036] By adopting the above technical scheme, the placement plate 7 moves down and abuts against the clamping block 93. Under the action of the guide slide, the clamping block 93 is driven to move to one side. The movement of the clamping block 93 drives the clamping rod 92 to move. The movement of the clamping rod 92 drives the clamping slide 94 to move and compress the clamping spring 95 until the placement plate 7 moves to the clamping hole and overlaps with the clamping block 93. The clamping spring 95 is reset, driving the clamping block 93 to insert into the clamping hole, clamping and fixing the placement plate 7 to prevent it from rising back. When the device is in use, it is convenient to clamp and fix the placement plate 7 after the placement plate 7 moves down to prevent it from rising back, thereby facilitating the staff to remove the collection bucket 6, thereby improving the practicality of use.

[0037] Specifically, a guide slot is provided at one end of the clamping block 93 , and a clamping hole matching the clamping block 93 is provided at one side of the placement plate 7 .

[0038] By adopting the above technical solution, the guide slide makes it easy for the placement plate 7 to move down and abut against the clamping block 93, which can drive the clamping block 93 to move to one side. The clamping hole makes it easy for the clamping block 93 to be inserted to fix the placement plate 7.

[0039] Specifically, damping telescopic rods 97 are provided on both sides below the placement plate 7, and one end of the damping telescopic rod 97 is fixedly connected to the placement plate 7, and the other end of the damping telescopic rod 97 is fixedly connected to the base 1.

[0040] By adopting the above technical solution, the damping telescopic rod 97 can help the placement plate 7 to rise slowly and stably when it is raised.

[0041] When the present embodiment is in use, the placing plate 7 moves downward and abuts against the clamping block 93. Under the action of the guide slide, the clamping block 93 is driven to move to one side. The movement of the clamping block 93 drives the clamping rod 92 to move. The movement of the clamping rod 92 drives the clamping slide block 94 to move and compress the clamping spring 95 until the placing plate 7 moves to the clamping hole and overlaps with the clamping block 93. The clamping spring 95 is reset, driving the clamping block 93 to be inserted into the clamping hole, clamping and fixing the placing plate 7 to prevent it from rising back. The damping telescopic rod 97 facilitates the placing plate 7 to rise slowly and stably. When the device is in use, it is convenient for the placing plate 7 to be clamped and fixed to prevent it from rising back after the placing plate 7 moves downward, thereby facilitating the staff to remove the collecting bucket 6 and improving the practicality of use.

[0042] The structure and use principle of the filter box 3, the connecting seat 5 and the collecting bucket 6 in the utility model have been disclosed in a filtering device for stem cell separation and extraction disclosed in Chinese patent application No. 202321246296.6. Its working principle is that the material to be filtered is injected from the feed pipe at the upper end of the side wall of the filter box 3, and the material is filtered out to the connecting seat 5 through the filter screen, and then enters the connecting part from the connecting seat 5 to the collecting bucket 6 to complete the filtering operation; the electric telescopic rod is started by the controller to drive the piston to move downward along the inner wall of the filter box 3, which can not only accelerate the material The filtering of the material can also scrape off the material attached to the inner wall of the filter box 3 to avoid the residue and loss of the material attached to the inner wall of the filter box 3. After the filtered material reaches the inside of the collecting bucket 6, the two sets of sealing plates are slid and pushed in until the two sets of sealing plates abut against each other, and the top of the collecting bucket 6 can be sealed. The placement plate 7 is pressed downward so that the abutment spring 8 is compressed. At this time, the connecting part is separated from the bottom end of the connecting seat 5, and the collecting bucket 6 can be pulled out from between the placement plate 7 and the connecting seat 5. The discharge valve on the side wall of the collecting bucket 6 can be opened to discharge the material inside the collecting bucket 6.

[0043] After the filter presses 4, filter 5 is started, filter 5 is started, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, filter 5 is started again, The clamping block 93 is driven to move to one side under the action of the guide slide, and the clamping block 93 moves to drive the clamping rod 92 to move, and the clamping rod 92 moves to drive the clamping slide block 94 to move and compress the clamping spring 95 until the placing plate 7 moves to the clamping hole and the clamping block 93 overlaps, and the clamping spring 95 is reset, driving the clamping block 93 to insert into the clamping hole, clamping and fixing the placing plate 7 to prevent it from rising, and the damping telescopic rod 97 is convenient for the placing plate 7 to rise slowly and stably when it is raised, so that when the device is in use, it is convenient for the placing plate 7 to be clamped and fixed to prevent it from rising after it moves down, thereby facilitating the staff to remove the collecting bucket 6, thereby improving the practicality of use.

[0044] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A filtration device for separation and extraction of stem cells, comprising a base, characterized in that: A bracket is arranged above the base, a filter box is arranged in the middle of the bracket, a convenient disassembly and assembly component is arranged below the filter box, a connecting seat is arranged below the convenient disassembly and assembly component, a collecting bucket is arranged below the connecting seat, a placing plate is arranged below the collecting bucket, an abutting spring is arranged below the placing plate, and a clamping assembly is arranged on one side of the placing plate.

2. A filtration device for separation and extraction of stem cells according to claim 1, characterized in that: The convenient disassembly and assembly component includes a mounting seat 1, a mounting seat 2, a square plug rod, a fixed block, a pull rod, a fixed slider and a fixed spring, wherein a mounting seat 1 is arranged below the filter box, a mounting seat 2 is arranged below the mounting seat 1, and the mounting seat 1 and the mounting seat 2 are abutted against each other, a square plug rod is inserted above the mounting seat 2, and the top of the square plug rod is fixed to the mounting seat 1, a fixed block is arranged on one side of the square plug rod, a pull rod is arranged at one end of the fixed block, a fixed slider is arranged above the pull rod, and a fixed spring is arranged on one side of the fixed slider.

3. A filtration device for separation and extraction of stem cells according to claim 2, characterized in that: A limit rod is arranged below the pull rod, a limit slider is arranged on one side of the limit rod, and a limit spring is arranged below the limit slider.

4. A filtration device for separation and extraction of stem cells according to claim 3, characterized in that: A ball is arranged at one end of the limit rod, and a fixing hole matching the fixing block is opened at one side of the square plug rod.

5. The filtration device for separation and extraction of stem cells according to claim 3, characterized in that: One end of the fixed sliding block is slidably connected to a guide sliding rod, and a limiting hole matching the limiting rod is provided below the pull rod.

6. The filtration device for separation and extraction of stem cells according to claim 1, characterized in that: The clamping assembly includes a clamping seat, a clamping rod, a clamping block, a clamping slide, a clamping spring and a stabilizing slide bar, wherein a clamping seat is provided on one side of the placement plate, a clamping rod is provided inside the clamping seat, a clamping block is provided at one end of the clamping rod, a clamping slide bar is provided below the clamping rod, a clamping spring is provided on one side of the clamping slide bar, and one end of the clamping slide bar is slidably connected to the stabilizing slide bar.

7. A filtration device for separation and extraction of stem cells according to claim 6, characterized in that: A guide sliding opening is provided at one end of the clamping block, and a clamping hole matching the clamping block is provided at one side of the placement plate.

8. The filtration device for separation and extraction of stem cells according to claim 5, characterized in that: Damping telescopic rods are arranged on both sides below the placement plate, one end of the damping telescopic rod is fixedly connected to the placement plate, and the other end of the damping telescopic rod is fixedly connected to the base.

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