Capsule filling jig of gastric retention system

By designing a gastric retention system capsule filling fixture including a mounting bracket, filling base and downpressure components, the problem of inconvenience in filling and packaging of gastric retention systems in the prior art is solved, a rapid and effective filling process is achieved, and the use of medicine is improved Compliance.

CN222488166UActive Publication Date: 2025-02-18JUNION THERAPEUTICS (XIAMEN) CO LTD
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Patent Information

Application Number
CN202420563519.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-22
Publication Date
2025-02-18
Estimated Expiration
2034-03-22

AI Technical Summary

Technical Problem

The prior art cannot quickly and effectively complete the filling and packaging of the gastric retention system, resulting in poor drug compliance.

Method used

A capsule filling fixture for gastric retention system is designed, including a mounting frame, a filling base and a downward pressure assembly. Through the cooperation of sliding channels and elastic positioning beads, the rapid folding and filling of gastric retention system is achieved.

Benefits of technology

The device can quickly and effectively fold the gastric retention system into the capsule shell, improving medication compliance and simplifying the operation process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of packaging of gastric retention systems, and discloses a capsule filling jig of a gastric retention system, which comprises a mounting frame, a filling base and a pressing component, a mounting plate and a vertical slide rail are fixed on the mounting frame, a filling mold is arranged on the mounting plate, a filling through hole is arranged on the filling mold, the filling base is positioned below the mounting plate, and the pressing component is positioned below the filling base. A filling groove opposite to the filling through hole is formed in the filling base, the downward pressing assembly comprises a first pressing rod and a second pressing rod which are vertically arranged, the first pressing rod and the second pressing rod are both slidably arranged on the vertical sliding rail, a sliding channel is formed in the second pressing rod in the axial direction, and the first pressing rod movably penetrates through the sliding channel; the capsule filling device for the gastric retention system is simple in structure and convenient to use, and the capsule filling process of the gastric retention system can be rapidly completed.
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Description

Technical Field

[0001] The utility model relates to the packaging field of a gastric retention system, in particular to a capsule filling jig of a gastric retention system. Background Art

[0002] Patients on long-term medication regimens have poor medication compliance, and current methods to improve compliance rates, such as educational interventions and counseling, have achieved only modest improvements. One way to reduce the frequency of dosing of oral dosage forms over extended durations is to add a self-expansion mechanism to the dosage form that physically prevents the dosage form from leaving the gastric cavity. In current gastric retention systems, in order to be encapsulated and retained in the stomach, the gastric retention system is generally prepared from an elastic polymer to form an elastomer. The elastomer generally includes an elastic center and an extension arm. The elastomer has two configurations, folded and unfolded. The elastomer is filled into the capsule shell in a folded configuration. After being taken into the body, the elastomer extension arm unfolds to form an unfolded configuration. There has been a lot of research in the prior art on gastric retention systems. For example, patents US11576859B2 or US20190262265A1 introduce a variety of star-shaped gastric retention systems, as shown in the attached disclosure. Figure 1 The structure has 6 elastic extension arms.

[0003] When preparing a gastric retention system product, the gastric retention system needs to be filled into a capsule shell in a folded configuration, and existing devices cannot quickly and effectively complete the filling and packaging of the gastric retention system. Utility Model Content

[0004] Therefore, it is necessary to provide a capsule filling jig for a gastric retention system to solve the problem of rapid folding and filling of a foldable gastric retention system.

[0005] To achieve the above-mentioned purpose, the utility model provides a capsule filling jig for a gastric retention system, comprising:

[0006] A mounting frame, a mounting plate and a vertical slide rail are fixed on the mounting frame, a filling mold is provided on the mounting plate, a filling through hole is provided on the filling mold, and the vertical slide rail is located above the mounting plate;

[0007] A filling base, the filling base is located below the mounting plate, and the filling base is provided with a filling groove corresponding to the filling through hole;

[0008] A pressing assembly includes a first pressing rod and a second pressing rod arranged vertically, wherein the first pressing rod and the second pressing rod are both slidably arranged on a vertical slide rail, and an axial sliding channel is arranged on the second pressing rod, and the first pressing rod moves through the sliding channel, and the first pressing rod and the second pressing rod correspond to the positions of the filling through hole.

[0009] Furthermore, the vertical slide rail includes a vertically arranged guide shaft, the top ends of the first pressure rod and the second pressure rod are respectively fixed with a first movable plate and a second movable plate, the first movable plate is located above the second movable plate, and the first movable plate and the second movable plate are both provided with linear bearings, and the linear bearings are sleeved on the guide shaft. The cooperation between the guide shaft and the linear bearings enables the first pressure rod and the second pressure rod to smoothly perform vertical up and down movements.

[0010] Furthermore, first positioning grooves are provided on both opposite sides of the first movable plate, first elastic positioning beads are provided on the mounting frame, the first positioning grooves and the first elastic positioning beads are engaged with each other, second positioning grooves are provided on both opposite sides of the second movable plate, second elastic positioning beads are provided on the mounting frame, the second positioning grooves and the second elastic positioning beads are engaged with each other. The provision of the elastic positioning beads plays a role in positioning and fixing the first movable plate and the second movable plate, preventing the two pressure rods from being pressed down when not in use, and further facilitating the use of the device.

[0011] Furthermore, the guide shaft is sleeved with a first spring and a second spring, the first spring is arranged between the first movable plate and the second movable plate, and the second spring is arranged between the second movable plate and the mounting plate. The first spring and the second spring prevent the first pressure rod and the second pressure rod from being pressed down suddenly, and maintain the stability of the process of pressing down the folding gastric retention system. At the same time, when the first movable plate and the second movable plate lose external force, the spring plays a certain reset role.

[0012] Furthermore, the first movable plate and the second movable plate are provided with pressing handles protruding from their sides, and the pressing handles of the first movable plate and the second movable plate are arranged staggered with each other. The pressing handles are convenient for the staff to apply force to press down.

[0013] Furthermore, the mounting plate is provided with a mounting opening, the filling mold is mounted on the mounting opening, and the upper surface of the filling mold is provided with a plurality of positioning bosses around the periphery of the filling through hole. The positioning bosses are used to fix the gastric retention system.

[0014] Furthermore, the top opening of the filling through hole has a circular chamfer, which is conducive to the smooth folding of the extension arm of the gastric retention system, so that the gastric retention system is pressed down to fill the capsule shell below.

[0015] Furthermore, a fixed base is fixed at the bottom of the mounting frame, the filling base is movably arranged on the fixed base, a protruding guide rail is arranged on the fixed base, a positioning block is arranged at one end of the guide rail, the filling base is provided with a slide groove corresponding to the guide rail, and the positioning block is blocked and connected with the filling base. The arrangement of the positioning block and the guide rail is conducive to positioning the filling base under the mounting plate.

[0016] Furthermore, the positioning block and the filling base are provided with adsorption magnetic blocks at corresponding positions. The adsorption magnets can fix the filling base and the positioning block, thereby facilitating the flexible fixation of the filling base.

[0017] The above technical solution has the following beneficial effects:

[0018] In the utility model, the filling groove is used to place the capsule shell, the filling mold is used to place the gastric retention system, and the first pressing rod is used to press the gastric retention system down into the filling through hole without affecting the folding of the extension arm of the gastric retention system. Then the second pressing rod can effectively and quickly press the folded gastric retention device down into the filling groove. Therefore, the utility model has a simple structure and is easy to use. The arrangement of the two pressing rods is conducive to the rapid folding and filling of the gastric retention system. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 FIG. 4 is a structural diagram of the gastric retention system according to a specific embodiment.

[0020] Figure 2 It is a three-dimensional structural diagram of the filling jig described in the specific implementation method.

[0021] Figure 3 It is a cross-sectional structural diagram of the filling jig described in the specific implementation method.

[0022] Figure 4 It is a structural diagram of the mounting plate described in the specific implementation method.

[0023] Figure 5 It is a structural diagram of the filling base described in the specific implementation method.

[0024] Figure 6 Schematic diagram of the filling and folding process of the gastric retention system according to the specific embodiment.

[0025] Description of reference numerals:

[0026] 1. Mounting frame; 11. Mounting plate; 111. Mounting port; 12. Vertical slide rail; 121. Guide shaft; 122. First spring; 123. Second spring; 13. Filling mold; 131. Filling through hole; 132. Positioning boss; 14. Fixed base; 141. Guide rail; 142. Positioning block; 143. Adsorption magnetic block; 15. First elastic positioning bead; 16. Second elastic positioning bead;

[0027] 2. Filling base; 21. Filling slot; 22. Slide slot;

[0028] 3. Pressing assembly; 31. First pressing rod; 32. Second pressing rod; 321. Sliding channel; 33. First movable plate; 34. Second movable plate; 35. Linear bearing; 36. First positioning groove; 37. Second positioning groove; 38. Pressing handle;

[0029] 4. Gastric retention system; 41. Elastic center; 42. Extension arm;

[0030] 5. Capsule shell. DETAILED DESCRIPTION

[0031] In order to explain the technical content, structural features, achieved objectives and effects of the technical solution in detail, the following is a detailed description in conjunction with specific embodiments and accompanying drawings.

[0032] See also Figure 1-6 The present embodiment discloses a capsule filling jig for a gastric retention system, comprising a mounting frame 1, a filling base 2 and a pressing assembly 3, wherein a mounting plate 11 and a vertical slide rail 12 are fixed to the mounting frame 1, a filling mold 13 is provided on the mounting plate 11, a filling through hole 131 is provided on the filling mold 13, the vertical slide rail 12 is located above the mounting plate 11, the filling base 2 is located below the mounting plate 11, a filling groove 21 corresponding to the position of the filling through hole 131 is provided on the filling base 2, and the pressing assembly 3 comprises a first pressing rod 31 and a second pressing rod 32 vertically arranged, the first pressing rod 31 and the second pressing rod 32 are located above the mounting plate 11, the first pressing rod 31 and the second pressing rod 32 are both slidably arranged on the vertical slide rail 12, a sliding channel 321 is axially arranged on the second pressing rod 32, the first pressing rod 31 moves through the sliding channel 321, and the first pressing rod 31 and the second pressing rod 32 correspond to the position of the filling through hole 131.

[0033] In this embodiment, the first pressure rod 31 moves through the axial sliding channel 321 of the second pressure rod 32. The first pressure rod 31 is set to be a pressure rod with a smaller diameter. During the pressing process, it will not hinder the initial folding of the extension arm 42 of the gastric retention system 4. The second pressure rod 32 is set to be a pressure rod with a larger diameter. The diameter of the second pressure rod 32 is larger than the diameter of the first pressure rod 31, but not larger than the diameter of the filling through hole 131. After the gastric retention system 4 is pressed down and folded, the first pressure rod 31 with a small diameter rises, and the second pressure rod 32 with a large diameter is pressed down, thereby pressing the gastric retention system 4 down into the capsule shell 5 in the filling groove 21, thereby completing the filling.

[0034] A fixed base 14 is fixed at the bottom of the mounting frame 1, and the filling base 2 is movably arranged on the fixed base 14. A protruding guide rail 141 is arranged on the fixed base 14, and a positioning block 142 is arranged at one end of the guide rail 141. The filling base 2 is provided with a slide groove 22 corresponding to the guide rail 141, and the positioning block 142 is blocked and connected with the filling base 2. The arrangement of the positioning block 142 and the guide rail 141 is conducive to positioning the filling base 2 under the mounting plate 11.

[0035] In this embodiment, a leveling device is provided on the bottom surface of the fixed base 14, which is conducive to the horizontal placement of the entire device.

[0036] The positioning block 142 and the filling base 2 are provided with correspondingly positioned adsorption magnetic blocks 143. The adsorption magnets can fix the filling base 2 and the positioning block 142, thereby facilitating the flexible fixation of the filling base 2.

[0037] The vertical slide rail 12 includes a vertically arranged guide shaft 121, and the top ends of the first pressure rod 31 and the second pressure rod 32 are respectively fixed with a first movable plate 33 and a second movable plate 34, the first movable plate 33 is located above the second movable plate 34, and the first movable plate 33 and the second movable plate 34 are both provided with a linear bearing 35, and the linear bearing 35 is sleeved on the guide shaft 121. The cooperation between the guide shaft 121 and the linear bearing 35 enables the first pressure rod 31 and the second pressure rod 32 to smoothly perform vertical movements up and down.

[0038] In this embodiment, there are two guide shafts 121 which are relatively arranged on both sides of the pressing assembly 3. The first movable plate 33 and the second movable plate 34 are transversely long strips. Both ends of the first movable plate 33 and the second movable plate 34 are provided with linear bearings 35.

[0039] The first movable plate 33 is provided with first positioning grooves 36 on both opposite side surfaces, the mounting frame 1 is provided with first elastic positioning beads 15, the first positioning grooves 36 and the first elastic positioning beads 15 are engaged with each other, the second movable plate 34 is provided with second positioning grooves 37 on both opposite side surfaces, the mounting frame 1 is provided with second elastic positioning beads 16, the second positioning grooves 37 and the second elastic positioning beads 16 are engaged with each other.

[0040] The provision of the elastic positioning beads plays a role in positioning and fixing the first movable plate 33 and the second movable plate 34, preventing the two pressure rods from being in a downward pressure state when there is no external force, further facilitating the use of the device.

[0041] In this embodiment, the positioning groove is a transverse groove on the movable plate, the cross-section of the positioning groove is an arc shape, and the elastic positioning bead is embedded with a spring. When an external force is applied to press the movable plate downward, the elastic positioning bead will pop out from the positioning groove.

[0042] A first spring 122 and a second spring 123 are sleeved on the guide shaft 121 . The first spring 122 is arranged between the first movable plate 33 and the second movable plate 34 , and the second spring 123 is arranged between the second movable plate 34 and the mounting plate 11 .

[0043] The first spring 122 and the second spring 123 prevent the first pressure rod 31 and the second pressure rod 32 from being pressed down suddenly, and maintain the stability of the process of pressing down the folded gastric retention system 4. At the same time, when the first movable plate 33 and the second movable plate 34 lose external force, the springs play a certain reset role.

[0044] In some embodiments, due to the setting of the first spring 122, when the first movable plate 33 is pressed downward, it will have a certain downward pressure on the second movable plate 34. In order to avoid the downward pressure of the second movable plate 34 at this time, the locking force of the second elastic positioning bead 16 can be set to be greater than the downward pressure of the first movable plate 33, or the operator can manually hold the second movable plate 34 to fix it when pressing down the first movable plate 33.

[0045] The first movable plate 33 and the second movable plate 34 are provided with pressing handles 38 protruding from their sides, respectively. The pressing handles 38 of the first movable plate 33 and the second movable plate 34 are staggered with each other. The pressing handles 38 are convenient for the staff to apply force to press down.

[0046] The mounting plate 11 is provided with a mounting opening 111, and the filling mold 13 is mounted on the mounting opening 111. The upper surface of the filling mold 13 is provided with a plurality of positioning bosses 132 around the periphery of the filling through hole 131. The positioning bosses 132 are used to fix the gastric retention system 4.

[0047] In this embodiment, the installation opening 111 passes through the upper and lower surfaces of the installation plate 11 , and a boss is provided in the installation opening 111 for installing the filling mold 13 .

[0048] The top opening of the filling through hole 131 has a rounded chamfer, which is conducive to the smooth folding of the extension arm 42 of the gastric retention system 4, so that the gastric retention system 4 is pressed down to fill the lower capsule shell 5.

[0049] The structure of the gastric retention system 4 is shown in the attached Figure 1 As shown, the gastric retention system 4 includes an elastic core 41 and elongated arms 42.

[0050] In this embodiment, the gastric retention system 4 having six extension arms 42 is folded and filled. Six spaced and surrounding positioning bosses 132 are provided on the upper surface of the filling mold 13.

[0051] The usage process of this embodiment is as follows:

[0052] Initial state: the first movable plate 33 and the second movable plate 34 are engaged with the first elastic positioning bead 15 and the second elastic positioning bead 16 respectively, the first pressing rod 31 and the second pressing rod 32 are fixed in position, the gastric retention system 4 is placed on the filling mold 13, the elastic center 41 corresponds to the filling through hole 131, the extension arm 42 is positioned between the positioning bosses 132, and half of the capsule shell 5 is placed in the filling groove 21;

[0053] First pressing: manually pressing down the corresponding pressing handle 38 on the first movable plate 33, so that the first pressing rod 31 passes through the sliding channel 321 of the second pressing rod 32, pressing down the elastic center 41, so that the extension arm 42 of the gastric retention system 4 is also folded upward by the reaction force of the filling mold 13. When the gastric retention system 4 is folded into the filling hole, the first pressing rod 31 rises and resets;

[0054] Second pressing: manually pressing down the corresponding pressing handle 38 on the second movable plate 34, so that the second pressing rod 32 presses down the entire gastric retention system 4 into the capsule shell 5 of the filling base 2, takes out the capsule shell 5, and assembles the other half of the capsule shell 5, thereby completing the filling of the gastric retention system 4.

[0055] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or terminal device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or terminal device. In the absence of further restrictions, the elements defined by the sentence "include..." or "comprise..." do not exclude the existence of other elements in the process, method, article or terminal device including the elements. In addition, in this article, "greater than", "less than", "exceed" and the like are understood to exclude the number itself; "above", "below", "within" and the like are understood to include the number itself.

[0056] Although the above embodiments have been described, once the technical personnel in the field know the basic creative concept, they can make other changes and modifications to these embodiments. Therefore, the above description is only the embodiment of the utility model, and it does not limit the patent protection scope of the utility model. Any equivalent structure or equivalent process transformation made by using the contents of the utility model specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the utility model.

Claims

1. A capsule filling jig for a gastric retention system, characterized in that: include: A mounting frame, a mounting plate and a vertical slide rail are fixed on the mounting frame, a filling mold is provided on the mounting plate, a filling through hole is provided on the filling mold, and the vertical slide rail is located above the mounting plate; A filling base, the filling base is located below the mounting plate, and the filling base is provided with a filling groove corresponding to the filling through hole; A pressing assembly includes a first pressing rod and a second pressing rod arranged vertically, wherein the first pressing rod and the second pressing rod are both slidably arranged on a vertical slide rail, and the second pressing rod is axially provided with a sliding channel, and the first pressing rod moves through the sliding channel, and the first pressing rod and the second pressing rod correspond to the positions of the filling through hole.

2. The capsule filling jig for the gastric retention system according to claim 1, characterized in that: The vertical slide rail includes a vertically arranged guide shaft, and the top ends of the first pressure rod and the second pressure rod are respectively fixed with a first movable plate and a second movable plate, the first movable plate is located above the second movable plate, and the first movable plate and the second movable plate are both provided with linear bearings, and the linear bearings are sleeved on the guide shaft.

3. The capsule filling jig for the gastric retention system according to claim 2, characterized in that: The first movable plate is provided with first positioning grooves on both opposite side surfaces, the mounting frame is provided with first elastic positioning beads, the first positioning groove and the first elastic positioning beads are engaged with each other, the second movable plate is provided with second positioning grooves on both opposite side surfaces, the mounting frame is provided with second elastic positioning beads, the second positioning groove and the second elastic positioning beads are engaged with each other.

4. The capsule filling jig for the gastric retention system according to claim 2, characterized in that: The guide shaft is sleeved with a first spring and a second spring, the first spring is arranged between the first movable plate and the second movable plate, and the second spring is arranged between the second movable plate and the mounting plate.

5. The capsule filling jig for the gastric retention system according to claim 2, characterized in that: The side edges of the first movable plate and the second movable plate are respectively provided with push-down handles, and the push-down handles of the first movable plate and the second movable plate are staggered with each other.

6. The capsule filling jig for the gastric retention system according to claim 1, characterized in that: The mounting plate is provided with a mounting opening, the filling mold is installed on the mounting opening, and the upper surface of the filling mold is provided with a plurality of positioning bosses around the periphery of the filling through hole.

7. The capsule filling jig for the gastric retention system according to claim 6, characterized in that: The top opening of the filling through hole has a circular arc chamfer.

8. The capsule filling jig for the gastric retention system according to claim 1, characterized in that: A fixed base is fixed at the bottom of the mounting frame, the filling base is movably arranged on the fixed base, a protruding guide rail is provided on the fixed base, a positioning block is provided at one end of the guide rail, the filling base is provided with a slide groove corresponding to the guide rail, and the positioning block is blocked and connected with the filling base.

9. The capsule filling jig for the gastric retention system according to claim 8, characterized in that: The positioning block and the filling base are provided with adsorption magnetic blocks corresponding to the positions.

Citation Information

Patent Citations

  • Gastric residence systems for sustained release of therapeutic agents and methods of use thereof

    US11576859B2

  • Geometric configurations for gastric residence systems

    US20190262265A1