POCT blood cell analyzer

Abstract

According to a blood cell counting mechanism of the POCT blood cell analyzer provided by the invention, a microporous sheet and a second electrode are arranged in a front cavity of a main body, a quick release part is detachably connected with the main body, and the quick release part is configured to be matched with the main body so as to limit the microporous sheet in the front cavity. The microporous sheet is limited in the front cavity through the cooperation of the quick-release part and the main body, and the quick-release part is detachably connected with the main body, so that under the condition that the microporous sheet needs to be replaced, a user can detach and separate the quick-release part from the main body, then the microporous sheet can be separated from the front cavity, and the user can replace the microporous sheet by himself without returning an instrument to a manufacturer for maintenance; the replacement difficulty of the microporous sheet in the blood cell counting mechanism is reduced, the maintenance cost of the POCT blood cell analyzer is reduced, and the use experience of a user on the POCT blood cell analyzer is improved.

Description

Technical Field

[0001] The present application relates to the technical field of sample detection, and in particular to a POCT blood cell analyzer. Background Art

[0002] The current impedance blood cell analyzer mainly uses micropores for counting and sampling. For the micropore sheet installed on the instrument, it is easy for the micropores on the micropore sheet to be blocked or even damaged due to impurities, contamination or coagulation of the test sample, making the instrument unable to be used normally. Due to the complex installation structure of the micropore sheet in the instrument, non-professionals cannot repair it. Users can only return the instrument to the manufacturer for repair, which makes the instrument difficult to repair and the repair cost high. Utility Model Content

[0003] In order to solve the above technical problems, the present application provides a POCT blood cell analyzer. The POCT blood cell analyzer comprises:

[0004] case;

[0005] A loading seat, used for receiving the reagent kit;

[0006] A blood cell counting mechanism is disposed in the housing; the blood cell counting mechanism can move relative to the reagent box;

[0007] The blood cell counting mechanism comprises:

[0008] The main body is provided with a front cavity and a rear cavity which are connected;

[0009] A microporous sheet, used to separate the front cavity and the rear cavity, wherein the microporous sheet is provided with micropores, and the front cavity and the rear cavity are connected through the micropores;

[0010] A first electrode, disposed in the rear cavity, and used for electrically connecting to a test sample in the rear cavity;

[0011] A second electrode, disposed in the front cavity, the second electrode being used to electrically connect to the test sample in the front cavity;

[0012] A quick-release piece is detachably connected to the main body, and the quick-release piece is configured to cooperate with the main body to confine the microporous sheet and / or the second electrode in the front cavity.

[0013] Wherein, a boss is arranged on one side of the quick release component close to the main body, the boss is arranged in the front cavity, and the boss cooperates with the main body to confine the second electrode and / or the microporous sheet in the front cavity.

[0014] When the blood cell counting mechanism replaces the microporous sheet, the quick-release part is disassembled from the main body, and the microporous sheet is detached from the front cavity. The quick-release part is also used to confine the replaced microporous sheet in the front cavity.

[0015] Wherein, the blood cell counting mechanism also includes a fixing part, at least one first connecting hole is provided on a side of the main body close to the quick-release part, the quick-release part is provided with at least one second connecting hole corresponding to the first connecting hole, and the fixing part is passed through the first connecting hole and the second connecting hole.

[0016] The second electrode includes a first cavity that penetrates axially, and the blood cell counting mechanism also includes a liquid absorbing member, which abuts against an annular plane of the second electrode away from one end of the microporous sheet, and the liquid absorbing member and the second electrode form a liquid absorbing channel.

[0017] Wherein, the diameter of the first cavity at one end close to the microporous sheet is larger than the diameter of the first cavity at one end close to the liquid absorbent member.

[0018] Wherein, the blood cell counting mechanism further includes a liquid discharge member and a switch valve, and the liquid discharge member is connected to the rear cavity through the switch valve to form a liquid discharge channel.

[0019] Wherein, the switch valve comprises a valve seat, a valve core and a drive block;

[0020] Wherein, the valve seat comprises a liquid flow pipeline, a liquid inlet of the liquid flow pipeline is connected to the rear cavity, and a liquid outlet of the liquid flow pipeline is connected to a liquid discharge member; the drive block is spaced apart from the valve seat to drive the valve core to move closer to or away from the liquid flow pipeline;

[0021] The driving block drives the valve core to move close to the liquid flow pipeline. When the valve core moves into the liquid flow pipeline and abuts against the pipe wall of the liquid flow pipeline, the valve core cuts off the liquid flow pipeline, and the switch valve is closed.

[0022] The driving block drives the valve core to move away from the liquid flow pipeline. When the valve core moves outside the liquid flow pipeline, the liquid flow pipeline is connected and the switch valve is opened.

[0023] Wherein, the POCT blood cell analyzer further comprises a pressure building mechanism, and the pressure building mechanism is connected to the rear cavity;

[0024] The pressure building mechanism is used to provide negative pressure to the rear cavity, and the liquid absorbing member is used to absorb the test sample from the reagent kit to flow the test sample into the rear cavity;

[0025] The pressure building mechanism is also used to provide positive pressure to the rear cavity, and the liquid discharge member is used to discharge the test sample in the rear cavity.

[0026] Wherein, the pressure building mechanism includes a pressure pump, a first valve, a second valve and a three-way joint, the first end of the pressure pump is connected to the first end of the three-way joint through the first valve, the second end of the pressure pump is connected to the second end of the three-way joint through the second valve, and the third end of the three-way joint is connected to the rear cavity of the blood cell counting mechanism.

[0027] Beneficial effects of the present application: Different from the prior art, the blood cell counting mechanism in the POCT blood cell analyzer provided in the present application includes a main body, a microporous sheet, a first electrode, a second electrode and a quick-release part. Among them, the main body is provided with a front cavity and a rear cavity that are connected, the microporous sheet is used to isolate the front cavity and the rear cavity, and the microporous sheet is provided with micropores, and the front cavity and the rear cavity are connected through the micropores. The first electrode is arranged in the rear cavity for electrically connecting to the detection sample in the rear cavity, and the second electrode is arranged in the front cavity for electrically connecting to the detection sample in the front cavity. The quick-release part is detachably connected to the main body, and the quick-release part is configured to cooperate with the main body to confine the second electrode and / or the microporous sheet in the front cavity. Through the cooperation of the quick-release part and the main body, the second electrode and the microporous sheet are confined in the front cavity, and the quick-release part is detachably connected to the main body. When the microporous sheet needs to be replaced, the user can disassemble and separate the quick-release part from the main body, and then the microporous sheet can be detached from the front cavity. The user can replace the microporous sheet by himself without returning the instrument to the manufacturer for repair, thereby reducing the difficulty of replacing the microporous sheet in the blood cell counting mechanism, reducing the maintenance cost of the POCT blood cell analyzer, and improving the user experience of the POCT blood cell analyzer. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0029] in:

[0030] Figure 1 It is a structural schematic diagram of the first embodiment of the POCT blood cell analyzer of the present application;

[0031] Figure 2 It is a structural schematic diagram of the first embodiment of the blood cell counting mechanism of the present application;

[0032] Figure 3 yes Figure 2 A schematic diagram of the structure of a local enlargement of region I in the middle;

[0033] Figure 4 It is a structural schematic diagram of the first embodiment of the switch valve of the present application;

[0034] Figure 5 It is a structural schematic diagram of the second embodiment of the POCT blood cell analyzer of the present application.

[0035] Figure numbers: POCT blood cell analyzer A; blood cell counting mechanism 1; main body 11; front chamber 111; rear chamber 112; first connecting hole 113; liquid inlet 114; liquid outlet 115; sealing member 116; microporous sheet 12; micropore 121; first electrode 13; second electrode 14; first cavity 141; first hole section 1411; second hole section 1412; third hole section 1413; quick release member 15; boss 151; second connecting hole 152; liquid suction member 16; liquid discharge member 17; switch valve 18; valve seat 181; liquid flow pipeline 1811; valve core 182; drive block 183; pressure building mechanism 2; pressure pump 21; first valve 22; second valve 23; three-way connector 24; reagent box B. DETAILED DESCRIPTION

[0036] The scheme of the embodiment of the present application is described in detail below in conjunction with the drawings of the specification.

[0037] In the following description, for the purpose of explanation rather than limitation, specific details such as specific system structures, interfaces, and technologies are provided to facilitate a thorough understanding of the present application.

[0038] Reference to "embodiments" in this application means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0039] The term "and / or" in this application is only a description of the association relationship of associated objects, indicating that there may be three relationships. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " in this article generally indicates that the objects associated before and after are in an "or" relationship. In addition, "many" in this article means two or more than two. In addition, the term "at least one" in this article means any combination of at least two of any one or more of a plurality of, for example, including at least one of A, B, and C, and can mean including any one or more elements selected from the set consisting of A, B, and C. In addition, the terms "first", "second", and "third" in this application are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features.

[0040] See also Figure 1 , Figure 1 It is a structural schematic diagram of the first embodiment of the POCT blood cell analyzer of the present application. The POCT blood cell analyzer A provided in this embodiment includes a housing, a loading seat and a blood cell counting mechanism 1. Among them, the loading seat is used to receive the reagent kit B, and the blood cell counting mechanism 1 is arranged in the housing and can move relative to the reagent kit B, such as moving in the horizontal direction or in the vertical direction, so as to approach the reagent kit B, absorb the test sample in the reagent kit B, and count and detect the test sample.

[0041] Among them, see Figure 2 and Figure 3 , Figure 2 It is a structural schematic diagram of the first embodiment of the blood cell counting mechanism of the present application; Figure 3 yes Figure 2 A partially enlarged structural diagram of the middle area B. The blood cell counting mechanism 1 provided in the embodiment of the present application comprises a main body 11, a microporous sheet 12, a first electrode 13, a second electrode 14 and a quick release member 15. The microporous sheet 12 comprises a gemstone sheet.

[0042] The main body 11 is provided with a front cavity 111 and a rear cavity 112 which are connected; the microporous sheet 12 is used to isolate the front cavity 111 and the rear cavity 112, and the microporous sheet 12 is provided with micropores 121, and the front cavity 111 and the rear cavity 112 are connected through the micropores 121. The first electrode 13 is provided in the rear cavity 112, and is used to be electrically connected to the detection sample in the rear cavity 112; the second electrode 14 is provided in the front cavity 111, and is used to be electrically connected to the detection sample in the front cavity 111. The quick release part 15 is detachably connected to the main body 11, and the quick release part 15 is configured to cooperate with the main body 11 to confine the microporous sheet 12 and / or the second electrode 14 in the front cavity 111.

[0043] In one embodiment, a mounting hole is provided on the side wall of the front cavity 111, and the quick-release component 15 can be installed on the main body 11 through the mounting hole, and the microporous sheet 12 located in the front cavity 111 is limited. When the microporous sheet 12 needs to be replaced, the quick-release component 15 can be removed from the mounting hole, and then the quick-release component 15 is removed and separated from the main body 11, and the user can pull the microporous sheet 12 out of the front cavity 111 through the mounting hole to replace the microporous sheet 12; or the quick-release component 15 is connected to the microporous sheet 12, and when the quick-release component 15 is removed from the mounting hole, the microporous sheet 12 can be pulled out of the front cavity 111 from the mounting hole along with the quick-release component 15, and the user can replace the microporous sheet 12.

[0044] In another embodiment, it may also be as follows Figure 2 As shown, the quick release part 15 is arranged on the side of the main body 11 toward which the front cavity 111 opens, and then the quick release part 15 is partially arranged at the opening of the front cavity 111 to confine the second electrode 14 and the microporous sheet 12 in the front cavity 111. When the microporous sheet 12 needs to be replaced, the user can disassemble and separate the quick release part 15 on the main body 11, and then the second electrode 14 and the microporous sheet 12 can fall off the front cavity 111. The user can replace the microporous sheet 12, and after the replacement, put the replaced microporous sheet 12 and the second electrode 14 back into the front cavity 111, and reconnect the quick release part 15 to the main body 11. The quick release part 15 confines the second electrode 14 and the microporous sheet 12 located in the front cavity 111 to ensure the detection function of the blood cell counting mechanism 1.

[0045] The quick-release member 15 can be connected to the main body 11 via a detachable structure such as a screw or a snap-on structure.

[0046] The microporous sheet 12 and / or the second electrode 14 are confined in the front cavity 111 by the quick-release part 15, and the quick-release part 15 is detachably connected to the main body 11. Therefore, when the microporous sheet 12 needs to be replaced, the user can directly disassemble and separate the quick-release part 15 from the main body 11, and then the microporous sheet 12 and / or the second electrode 14 can fall off in the front cavity 111, which is convenient for the user to replace the microporous sheet 12, reduces the difficulty of replacing the microporous sheet 12 in the blood cell counting mechanism 1, reduces the difficulty of repairing the POCT blood cell analyzer A, and improves the user's experience of using the POCT blood cell analyzer A.

[0047] In one embodiment, an electrode interface may be provided on the side wall of the front cavity 111, and then an external power source is connected to the second electrode 14 through the electrode interface to realize electrical connection between the second electrode 14 and the detection sample in the front cavity 111; and the external power source can also be connected to the first electrode 13 to realize electrical connection between the first electrode 13 and the detection sample in the rear cavity 112.

[0048] Alternatively, if Figure 2As shown, a boss 151 is provided on one side of the quick release member 15 close to the main body 11 . The boss 151 is disposed in the front cavity 111 . The boss 151 cooperates with the main body 11 to confine the second electrode 14 and / or the microporous sheet 12 in the front cavity 111 .

[0049] Specifically, when the quick-release part 15 is connected to the main body 11, the boss 151 is located in the front cavity 111, abutting against the second electrode 14, and then squeezing the second electrode 14 and the microporous sheet 12 to fix the second electrode 14 and the microporous sheet 12 in the front cavity 111, thereby preventing the second electrode 14 and the microporous sheet 12 from being not fixed and causing displacement, thereby affecting the counting and detection accuracy of the blood cell counting mechanism 1.

[0050] It can be understood that the setting height of the boss 151 can be determined by the depth of the front cavity 111, the length of the second electrode 14 and the thickness of the microporous sheet 12, so as to avoid the situation where the setting height of the boss 151 is too high, which may excessively squeeze the second electrode 14 and the microporous sheet 12, or the quick-release part 15 cannot be connected to the main body 11 due to the length relationship between the boss 151 and the second electrode 14 and the microporous sheet 12; or the setting height of the boss 151 is too low, and it cannot fix the second electrode 14 and the microporous sheet 12.

[0051] In one embodiment, when the blood cell counting mechanism 1 needs to replace the microporous sheet 12, the user can remove and separate the quick-release part 15 from the main body 11. Without the force of the boss 151 on the second electrode 14 and the microporous sheet 12, the second electrode 14 and the microporous sheet 12 can be detached from the front cavity 111, making it convenient for the user to replace the microporous sheet 12.

[0052] After the user puts the new microporous sheet 12 and the second electrode 14 back into the front cavity 111 , the user can connect the quick-release part 15 to the main body 11 , and then the quick-release part 15 sets the replaced microporous sheet 12 and the second electrode 14 in the front cavity 111 , completing the replacement of the microporous sheet 12 .

[0053] It can be understood that, since the boss 151 is arranged in the front cavity 111, the boss 151 also has a positioning function for the quick release part 15 installed on the main body 11. When the user wants to connect the quick release part 15 with the main body 11, the user can only confirm that the quick release part 15 is installed in place when the boss 151 is located in the front cavity 111, thereby improving the accuracy of the installation of the quick release part 15.

[0054] In summary, by providing a quick release part 15 that is detachable from the main body 11, when the quick release part 15 is connected to the main body 11, the quick release part 15 can confine the microporous sheet 12 and / or the second electrode 14 in the front cavity 111, fix the second electrode 14 and the microporous sheet 12, and improve the detection accuracy of the blood cell counting mechanism 1. When the microporous sheet 12 needs to be replaced, the user can directly disassemble and separate the quick release part 15 from the main body 11 and replace the microporous sheet 12, thereby reducing the difficulty of replacing the microporous sheet 12 in the blood cell counting mechanism 1.

[0055] Optionally, the blood cell counting mechanism 1 also includes a fixing part (not shown), and at least one first connecting hole 113 is provided on a side of the main body 11 close to the quick release part 15, and the quick release part 15 is provided with at least one second connecting hole 152 corresponding to the first connecting hole 113, and the fixing part is passed through the first connecting hole 113 and the second connecting hole 152.

[0056] In one embodiment, the fixing member may be the screw structure described above, and the screw is then inserted into the first connection hole 113 and the second connection hole 152, and fixed by a nut, so as to realize the detachable connection between the quick-release member 15 and the main body 11. When the microporous sheet 12 needs to be replaced, the user can directly remove the quick-release member 15 from the main body 11 by unscrewing the screw structure, and replace the microporous sheet 12. In other embodiments, the fixing member may also be other detachable structures, or the quick-release member 15 and the main body 11 may be connected by other detachable structures, and this application does not limit this.

[0057] Optionally, the second electrode 14 includes an axially through first cavity 141, and the blood cell counting mechanism 1 further includes a liquid absorbing member 16, which abuts against the annular plane of the second electrode 14 at one end away from the microporous sheet 12, and the liquid absorbing member 16 and the second electrode 14 form a liquid absorbing channel. The liquid absorbing member 16 may be a liquid absorbing pipe.

[0058] The test sample in the reagent kit can be absorbed into the front cavity 111 through the liquid absorption member 16 , and fully contact with the second electrode 14 through the first cavity 141 of the second electrode 14 , and be electrically connected with the second electrode 14 .

[0059] It is understandable that, since the second electrode 14 provided in this embodiment is a sleeve structure, the test sample will flow through the cavity of the second electrode 14, and the residual test sample may condense in the first cavity 141 of the second electrode 14 to block the liquid aspiration channel. Therefore, the user can also replace the second electrode 14 by disassembling and separating the quick-release member 15 from the main body 11 to avoid the situation where the liquid aspiration channel is blocked and the detection function of the blood cell counting mechanism 1 is affected.

[0060] In the second electrode 14 of one embodiment, the diameter of the first cavity 141 at one end close to the microporous sheet 12 is larger than the diameter of the first cavity 141 at one end close to the liquid absorbing member 16. The flow rate of the test sample is slowed down, and the liquid flow of the test sample through the micropores 121 of the microporous sheet 12 is more stable, which further ensures that the test sample is fully in contact with the second electrode 14. At the same time, it can also avoid the generation of bubbles due to the narrow space between the second electrode 14 and the microporous sheet 12 during the flow of the test sample, which affects the efficiency of the test sample passing through the microporous sheet 12 into the rear cavity 112, thereby improving the technical detection accuracy of the blood cell counting mechanism 1 on the test sample.

[0061] In one embodiment, the second electrode 14 and the liquid absorbing member 16 may also be an integrated structure, and then when the quick release member 15 is disposed on the side of the main body 11 toward which the front cavity 111 opens, when the user needs to replace the microporous sheet 12, the quick release member 15 may be disassembled and separated from the main body 11, and since the liquid absorbing member 16 is disposed on the boss 151, the liquid absorbing member 16 and the second electrode 14 may be separated from the main body 11 following the quick release member 15 to expose the microporous sheet 12 in the front cavity 111, so that the user can replace the microporous sheet 12 conveniently. When the second electrode 14 and the liquid absorbing member 16 are an integrated structure, the end of the integrated structure close to the microporous sheet 12 may be made of conductive material to achieve the function of electrical connection with the test sample, and the end of the integrated structure away from the microporous sheet 12 may be made of ordinary material to achieve the function of allowing the test sample to pass.

[0062] In another embodiment, the blood cell counting mechanism 1 may further include a plurality of seals 116, which may be respectively arranged between the microporous sheet 12 and the bottom of the front chamber 111, between the microporous sheet 12 and the second electrode 14, and between the second electrode 14 and the liquid absorbing component 16, so as to seal the gap between the two parts and ensure the sealing of the liquid absorbing channel.

[0063] In other embodiments, Figure 2As shown, the first cavity 141 includes a first hole segment 1411, a second hole segment 1412 and a third hole segment 1413, and the first hole segment 1411, the second hole segment 1412 and the third hole segment 1413 are sequentially arranged in a direction away from the microporous sheet 12, and the inner diameter of the second hole segment 1412 is smaller than the inner diameter of the third hole segment 1413, so that an annular plane is formed at the connection between the second hole segment 1412 and the third hole segment 1413, and one end of the liquid absorbing member 16 can abut on the annular plane, and the third hole segment 1413 positions the liquid absorbing member 16. In addition, the inner diameter of the first hole segment 1411 is larger than the inner diameter of the second hole segment 1412, so as to slow down the flow rate of the detection sample, avoid the detection sample from forming bubbles at the second electrode 14 and the microporous sheet 12, make the liquid flow of the detection sample passing through the micropores 121 of the microporous sheet 12 more stable, and further ensure that the detection sample is fully in contact with the second electrode 14, thereby improving the technical detection efficiency of the blood cell counting mechanism 1 for the detection sample.

[0064] Optionally, the blood cell counting mechanism 1 further includes a liquid discharge member 17 and a switch valve 18, and the liquid discharge member 17 is connected to the rear cavity 112 via the switch valve 18 to form a liquid discharge channel.

[0065] In one embodiment, see Figure 4 , Figure 4 The switch valve 18 includes a valve seat 181 , a valve core 182 and a drive block 183 .

[0066] Among them, the valve seat 181 includes a liquid flow pipeline 1811, the liquid inlet of the liquid flow pipeline 1811 is connected to the rear cavity 112, the liquid outlet of the liquid flow pipeline 1811 is connected to the discharge member 17, and the drive block 183 is spaced apart from the valve seat 181 to drive the valve core 182 to move closer to or away from the liquid flow pipeline 1811.

[0067] Specifically, the driving block 183 can drive the valve core 182 to move closer to the liquid flow pipeline 1811. When the valve core 182 moves into the liquid flow pipeline 1811 and abuts against the wall of the liquid flow pipeline 1811, the valve core 182 blocks the liquid flow pipeline 1811, and the liquid flow pipeline 1811 is cut off, and the switch valve 18 is closed. When the driving block 183 drives the valve core 182 to move away from the liquid flow pipeline 1811 and the valve core 182 moves outside the liquid flow pipeline 1811, the liquid flow pipeline 1811 is connected, and the switch valve 18 is opened.

[0068] In one embodiment, the valve core 182 may be an iron core, and the drive block 183 may be an electromagnetic component. When the drive block 183 is energized, it may attract or repel the valve core 182, so that the drive block 183 drives the valve core 182 to move closer to or away from the liquid flow pipeline 1811. In other embodiments, the drive block 183 and the valve core 182 may also be other structures, and the present application does not impose any limitation on this.

[0069] In the blood cell counting mechanism 1, see Figure 1 The main body 11 may include a liquid inlet 114 and a liquid outlet 115. The liquid inlet 114 is disposed at the bottom of the front chamber 111, so that the front chamber 111 is connected to the rear chamber 112. The microporous sheet 12 may be disposed on a side of the liquid inlet 114 close to the front chamber 111. The liquid outlet 115 is disposed at the bottom of the rear chamber 112, and the liquid discharge member 17 is connected to the liquid outlet 115 through the switch valve 18.

[0070] After the test sample enters the front cavity 111 from the liquid absorbing member 16 and contacts the second electrode 14, the test sample can further enter the rear cavity 112 through the micropores 121 and the liquid inlet 114 on the microporous sheet 12 and contact the first electrode 13. At this time, the first electrode 13 is electrically connected to the test sample in the rear cavity 112, and the second electrode 14 is electrically connected to the test sample in the front cavity 111. The external power supply, the first electrode 13, the second electrode 14, and the test sample form a complete current loop, and the blood cell counting mechanism 1 can count and detect the test sample.

[0071] Among them, since the first electrode 13 is arranged on the side wall of the rear cavity 112 and has a certain height difference with the liquid inlet of the microporous sheet 12, in the process of the detection sample entering the rear cavity 112 from the front cavity 111, the detection sample needs to have a certain amount of accumulation in the rear cavity 112 before the first electrode 13 can contact with the accumulated detection sample and achieve electrical connection. Therefore, at this time, the switch valve 18 at the drainage channel is in a closed state to prevent the detection sample from entering the rear cavity 112 from the front cavity 111 and being directly discharged through the drainage channel, and cannot be stored in the rear cavity 112, and cannot achieve electrical connection with the first electrode 13, which affects the counting and detection function of the blood cell counting mechanism 1.

[0072] After the blood cell counting mechanism 1 has finished counting and testing the test sample, the switch valve 18 can be opened, and the test sample in the rear cavity 112 can be discharged through the liquid discharge member 17. And because the liquid outlet 115 is arranged at the bottom of the rear cavity 112, it can be ensured that the test sample in the rear cavity 112 is completely discharged.

[0073] In one embodiment, the switch valve 18 and the drainage member 17 can be arranged on the main body 11, connected to the liquid outlet 115, and located on the same side of the main body 11 as the liquid inlet channel. The quick release member 15 has a through hole corresponding to the drainage member 17. When the quick release member 15 is connected to the main body 11, one end of the drainage member 17 passes through the through hole on the quick release member 15 and is exposed to the quick release member 15, thereby ensuring the drainage function of the drainage member 17.

[0074] Furthermore, when the user needs to replace the microporous sheet 12 of the blood cell counting mechanism 1, after the user disassembles the quick-release part 15 from the main body 11, the switch valve 18 and the discharge part 17 will not be separated from the main body 11 along with the quick-release part 15, thereby reducing the number of installation steps for other components except the microporous sheet 12 for the user, further reducing the difficulty of replacing the microporous sheet 12 in the blood cell counting mechanism 1 for the user, reducing the maintenance difficulty and maintenance cost of the POCT blood cell analyzer A, and improving the user's experience of the POCT blood cell analyzer A.

[0075] Alternatively, if Figure 5 As shown, Figure 5 The POCT blood cell analyzer A provided in the embodiment of the present application further comprises a pressure building mechanism 2 , which is connected to the rear cavity 112 of the blood cell counting mechanism 1 .

[0076] Specifically, the pressure building mechanism 2 is used to provide negative pressure to the rear cavity 112, and the liquid suction piece 16 is used to absorb the test sample from the reagent kit B to flow the test sample into the rear cavity 112; the pressure building mechanism 2 is also used to provide positive pressure to the rear cavity 112, and the liquid discharge channel is used to discharge the test sample in the rear cavity 112.

[0077] Specifically, when the blood cell counting mechanism 1 in the POCT blood cell analyzer A moves close to the test kit B so that the liquid absorption component 16 contacts the test sample in the test kit B, the switch valve 18 is closed, and the pressure building mechanism 2 provides negative pressure to the rear chamber 112. Due to the effect of the negative pressure, the test sample in the test kit B will enter the front chamber 111 through the liquid absorption component 16, and be electrically connected to the second electrode 14, and enter the rear chamber 112 through the micropores 121 and the liquid inlet 114 of the microporous sheet 12, and be electrically connected to the first electrode 13. Then, the blood cell counting mechanism 1 counts and detects the test sample through the current parameters between the first electrode 13 and the second electrode 14.

[0078] When the blood cell counting mechanism 1 completes the counting and detection of the test sample, the switch valve 18 opens, and the pressure building mechanism 2 provides positive pressure to the rear chamber 112. Under the action of the positive pressure, the test sample located in the rear chamber 112 can be discharged from the rear chamber 112 through the liquid outlet 115, the switch valve 18 and the liquid discharge member 17 in sequence. In one embodiment, when the liquid absorption member 16 of the blood cell counting mechanism 1 absorbs the reagent in the reagent box B, the end of the liquid discharge member 17 away from the rear chamber 112 can also be located in the reagent box B, and then the test sample after the counting and detection is completed can be returned to the reagent box B through the liquid discharge member 17, without the need to additionally set up a sample waste liquid collection device, thereby reducing the manufacturing cost of the POCT blood cell analyzer A.

[0079] It is understandable that, since there is no valve or other structure in the aspiration channel, when the pressure-building mechanism 2 provides positive pressure to the rear chamber 112, part of the test sample in the rear chamber 112 will be discharged from the aspiration channel, but due to the obstruction of the micropores 121 of the microporous sheet 12, the amount of the test sample discharged from the aspiration channel is not large and can be ignored. Therefore, in this embodiment, no valve structure is added to the aspiration channel to avoid increasing the volume and cost of the blood cell counting mechanism 1.

[0080] Optionally, the pressure building mechanism 2 includes a pressure pump 21, a first valve 22, a second valve 23 and a three-way connector 24. The first end of the pressure pump 21 is connected to the first end of the three-way connector 24 through the first valve 22, the second end of the pressure pump 21 is connected to the second end of the three-way connector 24 through the second valve 23, and the third end of the three-way connector 24 is connected to the rear cavity 112 of the blood cell counting mechanism 1.

[0081] In one embodiment, when the pressure building mechanism 2 needs to provide negative pressure for the rear chamber 112, the first valve 22 connected to the negative pressure passage of the pressure pump 21 may be opened, while the second valve 23 connected to the positive pressure passage of the pressure pump 21 may be closed, and the pressure pump 21 provides negative pressure to the rear chamber 112 through the first valve 22 and the first end of the three-way joint 24; when the pressure building mechanism 2 needs to provide positive pressure to the rear chamber 112, the second valve 23 connected to the positive pressure passage of the pressure pump 21 is opened, while the first valve 22 connected to the negative pressure passage of the pressure pump 21 is closed, and the pressure pump 21 provides positive pressure to the rear chamber 112 through the second valve 22 and the second end of the three-way joint 24.

[0082] In another embodiment, the first valve 22 and the second valve 23 may also be combined into a two-position three-way valve to realize switching of the positive pressure or negative pressure provided by the pressure pump 21 to the rear chamber 112. When switching of the positive pressure or negative pressure provided by the pressure pump 21 to the rear chamber 112 is realized, this embodiment does not limit the number and types of valves included in the pressure building mechanism 2.

[0083] In summary, in the blood cell counting mechanism 1 of the POCT blood cell analyzer A provided in the embodiment of the present application, the microporous sheet 12 and the second electrode 14 are located in the front cavity 111 of the main body 11, and the quick release part 15 is detachably connected to the main body 11. When the quick release part 15 is connected to the main body 11, the quick release part 15 fixes the second electrode 14 and / or the microporous sheet 12 in the front cavity 111. When the blood cell counting mechanism 1 needs to replace the microporous sheet 12, the user can directly disassemble and separate the quick release part 15 from the main body 11, and then the second electrode 14 and / or the microporous sheet 12 are detached from the front cavity 111. The user can directly replace the microporous sheet 12 and / or the second electrode 14, and after the microporous sheet 12 or the second electrode 14 is replaced, the user reconnects the quick release part 15 to the main body 11 to restore the counting and detection function of the blood cell counting mechanism 1. The difficulty of replacing the microporous sheet 12 or the second electrode 14 in the blood cell counting mechanism 1 is reduced, and users can perform the replacement without the need for professional personnel, thereby reducing the maintenance difficulty and maintenance cost of the POCT blood cell analyzer A and improving the user experience of the POCT blood cell analyzer A.

[0084] The above description is only an implementation method of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A POCT blood cell analyzer, characterized in that: include: case; A loading seat, used for receiving the reagent kit; A blood cell counting mechanism is disposed in the housing; The blood cell counting mechanism can move relative to the reagent box; The blood cell counting mechanism comprises: A main body is provided with a front cavity and a rear cavity which are connected; A microporous sheet, used to separate the front cavity and the rear cavity, wherein the microporous sheet is provided with micropores, and the front cavity and the rear cavity are connected through the micropores; A first electrode, disposed in the rear cavity, and used for electrically connecting to a detection sample in the rear cavity; A second electrode, disposed in the front cavity, the second electrode being used to electrically connect to the test sample in the front cavity; A quick-release piece is detachably connected to the main body, and the quick-release piece is configured to cooperate with the main body to confine the microporous sheet and / or the second electrode in the front cavity.

2. The POCT blood cell analyzer according to claim 1, characterized in that: A boss is provided on one side of the quick-release component close to the main body, the boss is provided in the front cavity, and the boss cooperates with the main body to confine the second electrode and / or the microporous sheet in the front cavity.

3. The POCT blood cell analyzer according to claim 1, characterized in that: When the blood cell counting mechanism replaces the microporous sheet, the quick-release part is disassembled from the main body, and the microporous sheet is separated from the front cavity. The quick-release part is also used to confine the replaced microporous sheet in the front cavity.

4. The POCT blood cell analyzer according to claim 1, characterized in that: The blood cell counting mechanism also includes a fixing part. The main body is provided with at least one first connecting hole on one side close to the quick-release part. The quick-release part is provided with at least one second connecting hole corresponding to the first connecting hole. The fixing part is passed through the first connecting hole and the second connecting hole.

5. The POCT blood cell analyzer according to claim 1, characterized in that: The second electrode includes a first cavity that penetrates axially, and the blood cell counting mechanism also includes a liquid absorbing member, which abuts against an annular plane of the second electrode away from one end of the microporous sheet, and the liquid absorbing member and the second electrode form a liquid absorbing channel.

6. The POCT blood cell analyzer according to claim 5, characterized in that: The diameter of the first cavity at one end close to the microporous sheet is larger than the diameter of the first cavity at one end close to the liquid absorbent member.

7. The POCT blood cell analyzer according to claim 5, characterized in that: The blood cell counting mechanism further comprises a liquid discharge member and a switch valve, wherein the liquid discharge member is connected to the rear cavity through the switch valve to form a liquid discharge channel.

8. The POCT blood cell analyzer according to claim 7, characterized in that: The switch valve comprises a valve seat, a valve core and a driving block; Wherein, the valve seat comprises a liquid flow pipeline, a liquid inlet of the liquid flow pipeline is connected to the rear cavity, and a liquid outlet of the liquid flow pipeline is connected to a liquid discharge member; the drive block is spaced apart from the valve seat to drive the valve core to move closer to or away from the liquid flow pipeline; The driving block drives the valve core to move close to the liquid flow pipeline. When the valve core moves into the liquid flow pipeline and abuts against the pipe wall of the liquid flow pipeline, the valve core cuts off the liquid flow pipeline, and the switch valve is closed. The driving block drives the valve core to move away from the liquid flow pipeline. When the valve core moves outside the liquid flow pipeline, the liquid flow pipeline is connected and the switch valve is opened.

9. The POCT blood cell analyzer according to claim 7, characterized in that: The POCT blood cell analyzer further comprises a pressure building mechanism, and the pressure building mechanism is connected to the rear cavity; The pressure building mechanism is used to provide negative pressure to the rear cavity, and the liquid absorbing member is used to absorb the test sample from the reagent kit to flow the test sample into the rear cavity; The pressure building mechanism is also used to provide positive pressure to the rear cavity, and the liquid discharge member is used to discharge the test sample in the rear cavity.

10. The POCT blood cell analyzer according to claim 9, characterized in that: The pressure building mechanism includes a pressure pump, a first valve, a second valve and a three-way joint. The first end of the pressure pump is connected to the first end of the three-way joint through the first valve, the second end of the pressure pump is connected to the second end of the three-way joint through the second valve, and the third end of the three-way joint is connected to the rear cavity of the blood cell counting mechanism.

Images