Anti-pollution cell culture device

By using a rotating mechanism and a clamping mechanism in the cell culture device, the problem of poor sealing of the existing device is solved, and higher sealing performance and more efficient cell culture process are achieved.

CN222574672UActive Publication Date: 2025-03-07ZHONGKE SHENGQUAN (SHANDONG) BIOENGINEERING CO LTD
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Patent Information

Application Number
CN202421062033.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-16
Publication Date
2025-03-07
Estimated Expiration
2034-05-16

AI Technical Summary

Technical Problem

When the existing cell culture device is undergoing cell culture, there is a gap between the rotary shaft and the side wall of the culture box, which has poor sealing effect, resulting in air entering, causing cell contamination, and affecting the culture effect and work quality.

Method used

An anti-pollution cell culture device is designed, using a rotating mechanism and a clamping mechanism. The connecting rod and the gear ring are driven to rotate through the rotating block, and the rotating plate is driven to rotate, and the compartment is replaced to the movable door. Other compartments are kept sealed, and the position of the rotating plate is locked by the limit block and the spring to improve the sealing performance. At the same time, the movable door is quickly installed through the clamping mechanism, and the sealing effect is enhanced by using the sealing layer.

Benefits of technology

The sealing performance of the culture device is improved, prevents air from entering, reduces cell contamination, and improves the working efficiency and quality of cell culture.

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Abstract

The utility model discloses an anti-pollution cell culture device, which relates to the technical field of cell culture and comprises a culture device body, a rotating plate is rotatably arranged in the culture device body, a plurality of partition plates are fixedly arranged on the circumference of the top of the rotating plate, and the tops of the partition plates abut against the inner top of the culture device body. A mounting groove is formed in the side wall of the culture device body, the culture device further comprises a rotating mechanism and a clamping mechanism, the rotating mechanism convenient for driving the rotating plate to rotate is arranged at the bottom in the culture device body, and the clamping mechanism used for quickly mounting the movable door is arranged at the bottom of the mounting groove. The rotating block is used for driving the connecting rod to move, so that the gear ring is driven to rotate, and the rotating plate is driven to rotate, so that a compartment needing cell culture is replaced to a movable door, other compartments are kept in a sealed state, the practicability of the device is improved, the influence on cell culture is reduced, and the working efficiency is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to an anti-pollution cell culture device. Background Art

[0002] Cell culture refers to a method of simulating the in vivo environment in vitro to enable cells to survive, grow, reproduce and maintain their main structures and functions. Cell culture technology is an important and commonly used technology in cell biology research methods. Cell culture can not only obtain a large number of cells, but also be used to study cell signal transduction, cell anabolism, cell growth and proliferation, etc.

[0003] An isolation and pollution-proof stem cell culture device is described in a patent with an existing patent announcement number of CN 215757395 U, wherein the described device comprises a culture box, a base is installed at the bottom of the culture box, a load-bearing plate is installed inside the culture box, a driving motor is installed at both ends of one side of a door of the culture box, a rotating shaft is installed at the output end of the driving motor, a base rod is threadedly installed between the rotating shafts, and an isolation plate is installed at the bottom of the base rod. The driving motor drives the rotating shaft to rotate, and then drives the isolation plate to move up and down inside the culture box, so that when stem cell culture is carried out, sufficient space can be temporarily isolated to complete the culture experiment. However, when the device is used for cell culture, there is still a gap between the rotating shaft and the side wall of the culture box, and the sealing effect is poor, which will allow air to enter, thereby easily causing bacteria in the air to contaminate other cells inside the culture box, affecting the cell culture effect, and reducing the work quality and efficiency of cell culture.

[0004] Based on this, a contamination-proof cell culture device is now provided, which can eliminate the disadvantages of the existing devices. Utility Model Content

[0005] The utility model aims to provide a contamination-proof cell culture device to solve the problem that in the existing device, when cell culture is carried out, there is still a gap between the rotating shaft and the side wall of the culture box, the sealing effect is poor, and air can enter, which easily leads to contamination of bacteria in the air and cells inside the cell culture device, affecting the cell culture effect and reducing the work quality and efficiency of the cell culture.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A contamination-proof cell culture device comprises a culture device body, a rotating plate is rotatably provided inside the culture device body, a plurality of partitions are provided on a fixed circumference on the top of the rotating plate, the top of the partitions abuts against the top of the culture device body, a mounting groove is provided on the side wall of the culture device body, a movable door is clamped in the mounting groove, and further comprises a rotating mechanism and a clamping mechanism, a rotating mechanism is provided at the bottom of the culture device body for driving the rotating plate to rotate, and a clamping mechanism is provided at the bottom of the mounting groove for quickly installing the movable door.

[0008] On the basis of the above technical solutions, the present invention also provides the following optional technical solutions:

[0009] In an optional solution: an observation window is provided on the top of the culture device body.

[0010] In an optional solution: a handle is fixedly provided on the top of the movable door.

[0011] In an optional scheme: the rotating mechanism includes a rotating block, a connecting rod, a rotating groove, a gear ring, a side plate, a first limit block, and a first spring; a gear ring is rotatably provided at the bottom of the inner bottom of the culture device body, and the top of the gear ring is fixedly connected to the bottom of the rotating plate; a side plate is fixedly provided at the bottom of the inner bottom of the culture device body, and a first spring is fixedly provided on the side wall of the side plate; a first limit block is fixedly connected to the end of the first spring, and the first limit block is meshingly connected to the gear ring; a rotating groove is opened on the side wall of the culture device body, and a connecting rod is rotatably provided in the rotating groove, and the end of the connecting rod is fixedly connected to the side wall of the gear ring, and the other end of the connecting rod is fixedly connected to the rotating block.

[0012] In an optional solution: the side wall of the culture device body at the position of the rotating groove is provided with scale lines.

[0013] In an optional solution: the side wall of the rotating block is provided with a plurality of anti-slip grooves.

[0014] In an optional scheme: the clamping mechanism includes a limit groove, a docking block, a fixed groove, a second limit block, a clamping groove, a clamping block, a second spring, and a groove; the side walls of the installation groove are symmetrically provided with limit grooves; the side walls of the movable door are fixedly provided with a second limit block adapted to the limit groove; the bottom of the installation groove is symmetrically provided with clamping grooves; the side walls of the clamping groove are symmetrically provided with grooves; the side walls of the groove are fixedly provided with a second spring; the ends of the second spring are fixedly connected with a clamping block; the bottom of the movable door is symmetrically provided with docking blocks adapted to the clamping grooves; the side walls of the docking block are symmetrically provided with fixing grooves adapted to the clamping block.

[0015] In an optional solution: a sealing layer is provided on the side wall of the movable door.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0017] 1. The utility model achieves the effect of isolating cultured cells by setting a rotating mechanism, and utilizes a rotating block to drive the connecting rod to move, thereby driving the gear ring to rotate, and then driving the rotating plate to rotate, so that the compartment that needs to be cultured for cells can be replaced to the movable door, while other compartments remain in a sealed state. The position of the rotating plate is locked by the meshing connection between the first limit block and the gear ring, thereby improving the sealing performance of the enclosed space between the culture device body and the partition, improving the practicability of the device, reducing the impact on cell culture, and improving the work efficiency of cell culture.

[0018] 2. The utility model achieves the effect of quickly connecting the movable door by setting a locking mechanism. The movable door is locked into the installation groove by using the second limit block, and then the docking block is locked into the locking groove. The second spring is used to lock the locking block into the fixed groove to achieve the effect of quickly connecting the movable door, improve the convenience of the device, and use the sealing layer to make the sealing effect of the culture device body better, avoid air entering the interior of the culture device body to cause cell contamination, and improve the quality of cell culture. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0020] Figure 2 It is a structural schematic diagram of the installation slot in the utility model.

[0021] Figure 3 It is a partial enlarged view of A in the utility model.

[0022] Figure 4 It is a structural schematic diagram of the partition in the utility model.

[0023] Figure 5 It is a schematic diagram of the internal structure of the utility model.

[0024] Figure 6 This is a first structural schematic diagram of the movable door in the utility model.

[0025] Figure 7 This is a second structural schematic diagram of the movable door in the utility model.

[0026] Notes on figure marks: culture device body 100, observation window 101, movable door 102, handle 103, mounting groove 104, limiting groove 105, docking block 106, fixing groove 107, second limiting block 108, rotating block 200, connecting rod 201, rotating groove 202, partition 203, rotating plate 204, gear ring 205, side plate 206, first limiting block 207, first spring 208, snap-in groove 300, snap block 301, second spring 302, groove 303. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments.

[0028] Example 1

[0029] In one embodiment, Figure 1-Figure 7 As shown, a contamination-proof cell culture device comprises a culture device body 100, wherein a rotating plate 204 is rotatably provided inside the culture device body 100, a plurality of partitions 203 are provided on a fixed circumference on the top of the rotating plate 204, the top of the partition 203 abuts against the top of the culture device body 100, a mounting groove 104 is provided on the side wall of the culture device body 100, a movable door 102 is clamped in the mounting groove 104, a rotating mechanism and a clamping mechanism are further included, a rotating mechanism for driving the rotating plate 204 to rotate is provided at the bottom of the culture device body 100, and a clamping mechanism for quickly installing the movable door 102 is provided at the bottom of the mounting groove 104.

[0030] In one embodiment, Figure 1 As shown, an observation window 101 is provided on the top of the culture device body 100. The observation window 101 is provided to facilitate the user to observe the specific conditions of cell culture, thereby improving the practicability of the device.

[0031] In one embodiment, Figure 6-Figure 7 As shown, a handle 103 is fixedly provided on the top of the movable door 102. The movable door 102 is moved by using the handle 103, which facilitates the user to open and close the movable door 102, thereby improving the convenience of the device.

[0032] In one embodiment, Figure 1-Figure 5As shown, the rotating mechanism includes a rotating block 200, a connecting rod 201, a rotating groove 202, a gear ring 205, a side plate 206, a first limit block 207, and a first spring 208. A gear ring 205 is rotatably provided at the bottom of the culture device body 100. The top of the gear ring 205 is fixedly connected to the bottom of the rotating plate 204. A side plate 206 is fixedly provided at the bottom of the culture device body 100. A first spring 208 is fixedly provided on the side wall of the side plate 206. The end of the first spring 208 is fixedly connected to the first limit block 207. The first limit block 207 is meshed with the gear ring 205. A rotating groove 202 is opened on the side wall of the culture device body 100. A connecting rod 201 is rotatably provided in the rotating groove 202. The end of the connecting rod 201 The connecting rod 201 is fixedly connected to the side wall of the toothed ring 205, and the other end of the connecting rod 201 is fixedly connected to a rotating block 200. The rotating block 200 is used to drive the connecting rod 201 to move, thereby driving the toothed ring 205 to rotate, and then driving the rotating plate 204 to rotate, so that the compartment that needs to be cultured for cells can be replaced to the movable door 102, while other compartments remain in a sealed state. The position of the rotating plate 204 is locked by the meshing connection between the first limit block 207 and the toothed ring 205, thereby improving the sealing performance of the enclosed space between the culture device body 100 and the partition 203, improving the practicability of the device, preventing bacteria in the air from contaminating other cells inside the culture device body 100, reducing the impact on cell culture, and improving the work quality and efficiency of cell culture.

[0033] In one embodiment, Figure 4-Figure 5 As shown, the side wall of the culture device body 100 at the position of the rotation slot 202 is provided with scale lines, which play an auxiliary role and facilitate the user to judge the required rotation angle.

[0034] In one embodiment, Figure 4 As shown, the side wall of the rotating block 200 is provided with a plurality of anti-skid grooves to play an anti-skid role.

[0035] In one embodiment, Figure 1-Figure 7As shown, the clamping mechanism includes a limiting groove 105, a docking block 106, a fixing groove 107, a second limiting block 108, a clamping groove 300, a clamping block 301, a second spring 302, and a groove 303. The side wall of the installation groove 104 is symmetrically provided with the limiting groove 105, and the side wall of the movable door 102 is fixedly provided with a second limiting block 108 adapted to the limiting groove 105. The bottom of the installation groove 104 is symmetrically provided with a clamping groove 300, and the side wall of the clamping groove 300 is symmetrically provided with a groove 303. The side wall of the groove 303 is fixedly provided with a second spring 302. The end of the second spring 302 is fixedly connected with a clamping block 301, and the bottom of the movable door 102 is fixedly and symmetrically provided with a docking block 106 adapted to the clamping groove 300, and the side wall of the docking block 106 is symmetrically provided with a fixing groove 107 adapted to the clamping block 301. The movable door 102 is clamped into the installation groove 104 by using the second limit block 108, and then the docking block 106 is clamped into the clamping groove 300. The clamping block 301 is clamped into the fixing groove 107 through the second spring 302, so as to achieve the effect of quickly clamping the movable door 102 and improve the convenience of the device.

[0036] Example 2

[0037] In one embodiment, Figure 6-Figure 7 As shown, the side wall of the movable door 102 is provided with a sealing layer, so that the sealing effect of the culture device body 100 is better, and air is prevented from entering the culture device body 100 to cause cell contamination, thereby improving the quality of cell culture.

[0038] Working principle: When in use, the rotating block 200 is used to drive the connecting rod 201 to move, thereby driving the gear ring 205 to rotate, and then driving the rotating plate 204 to rotate, so that the compartment that needs to be cultured for cells can be replaced to the movable door 102, while other compartments remain sealed. The first limit block 207 is engaged with the gear ring 205 to lock the position of the rotating plate 204, thereby improving the sealing performance of the closed space between the culture device body 100 and the partition 203, improving the practicability of the device, and preventing bacteria in the air from contacting the culture device body 100. 00, thereby reducing the impact on cell culture and improving the work efficiency of cell culture. After the cell culture is completed, the second limiting block 108 is used to snap the movable door 102 into the installation groove 104, and then the docking block 106 is snapped into the snap-in groove 300. The second spring 302 is used to snap the block 301 into the fixed groove 107 to achieve the effect of quickly snapping the movable door 102, thereby improving the convenience of the device. At the same time, the sealing layer is set to make the sealing effect of the culture device body 100 better, thereby improving the quality of cell culture.

[0039] The above is only a specific implementation of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.

Claims

1. A contamination-proof cell culture device, comprising a culture device body (100), wherein a rotating plate (204) is rotatably provided inside the culture device body (100), a plurality of partitions (203) are fixedly provided on the top of the rotating plate (204), the top of the partition (203) abuts against the top of the culture device body (100), a mounting groove (104) is provided on the side wall of the culture device body (100), a movable door (102) is clamped in the mounting groove (104), and the characteristics are as follows: It also includes a rotating mechanism and a snap-on mechanism. The inner bottom of the culture device body (100) is provided with a rotating mechanism for driving the rotating plate (204) to rotate, and the bottom of the installation groove (104) is provided with a snap-on mechanism for quickly installing the movable door (102).

2. The anti-pollution cell culture device according to claim 1, characterized in that: An observation window (101) is provided on the top of the culture device body (100).

3. The anti-pollution cell culture device according to claim 2, characterized in that: A handle (103) is fixedly provided on the top of the movable door (102).

4. The anti-pollution cell culture device according to claim 1, characterized in that: The rotating mechanism comprises a rotating block (200), a connecting rod (201), a rotating groove (202), a gear ring (205), a side plate (206), a first limit block (207), and a first spring (208); a gear ring (205) is rotatably provided at the bottom of the culture device body (100); the top of the gear ring (205) is fixedly connected to the bottom of the rotating plate (204); a side plate (206) is fixedly provided at the bottom of the culture device body (100); and a first spring (208) is fixedly provided on the side wall of the side plate (206). A spring (208), the end of the first spring (208) is fixedly connected to a first limit block (207), the first limit block (207) is meshed with the gear ring (205), the side wall of the culture device body (100) is provided with a rotation groove (202), a connecting rod (201) is rotatably provided in the rotation groove (202), the end of the connecting rod (201) is fixedly connected to the side wall of the gear ring (205), and the other end of the connecting rod (201) is fixedly connected to a rotating block (200).

5. The anti-pollution cell culture device according to claim 4, characterized in that: The side wall of the culture device body (100) at the position of the rotating groove (202) is provided with scale lines.

6. The anti-pollution cell culture device according to claim 4, characterized in that: The side wall of the rotating block (200) is provided with a plurality of anti-slip grooves.

7. The anti-pollution cell culture device according to claim 1, characterized in that: The clamping mechanism comprises a limiting groove (105), a docking block (106), a fixing groove (107), a second limiting block (108), a clamping groove (300), a clamping block (301), a second spring (302), and a groove (303); the limiting groove (105) is symmetrically provided on the side wall of the installation groove (104); the second limiting block (108) adapted to the limiting groove (105) is fixedly provided on the side wall of the movable door (102); and the bottom of the installation groove (104) is symmetrically provided with a clamping block (301). A connecting groove (300) is provided, and a groove (303) is symmetrically arranged on the side wall of the connecting groove (300), a second spring (302) is fixedly arranged on the side wall of the groove (303), and a clamping block (301) is fixedly connected to the end of the second spring (302), and a docking block (106) adapted to the connecting groove (300) is fixedly and symmetrically arranged on the bottom of the movable door (102), and a fixing groove (107) adapted to the clamping block (301) is symmetrically opened on the side wall of the docking block (106).

8. The anti-pollution cell culture device according to claim 7, characterized in that: The side wall of the movable door (102) is provided with a sealing layer.

Citation Information

Patent Citations

  • Isolated anti-pollution stem cell culture device

    CN215757395U