25 results about "Blood donor" patented technology

The invention provides an SNP (Single Nucleotide Polymorphism) site of an ABO blood group variant, and an A subtype variant blood group identification kit and method, and relates to the technical field of biology. The SNP sites of the ABO blood group variant comprise the 155th c.155Ggt from an initiation codon of an ABO gene coding region, and the 155th c.155Ggt from the initiation codon of the ABO gene coding region; mutation of T. A substance for detecting the SNP site of the ABO blood group variant can be applied to preparation of an A-subtype variant blood group identification method and product so as to be effectively applied to rapid detection of patients and blood donors, the A-subtype variant blood group of an individual can be defined, and possible blood transfusion reaction can be prevented in time.

The invention provides an SNP (Single Nucleotide Polymorphism) site of an ABO blood group variant, and a B subtype variant blood group identification kit and method, and relates to the technical field of biology. The SNP (Single Nucleotide Polymorphism) sites of the ABO blood group variant comprise the 842th c.842Cgt from an initiation codon of an ABO * B.01 allele coding region of an ABO gene; mutation of T. A substance for detecting the SNP site of the ABO blood group variant can be applied to preparation of a B subtype variant blood group identification method and product, so that the substance can be effectively applied to rapid detection of patients and blood donors, the B subtype variant blood group of an individual can be defined, and potential possible blood transfusion reaction can be prevented in time.

The invention discloses blood component single sampling equipment capable of monitoring in real time in the field of blood treatment equipment. The equipment comprises a blood sampling module, a centrifugal separation module, a component collection module and an anticoagulant conveying module, and further integrates a multi-dimensional real-time monitoring system and a closed-loop self-adaptive regulation and control module. The multi-dimensional real-time monitoring system comprises an online micro-fluidic component detection unit, a physiological parameter monitoring unit and an equipment operation monitoring unit, can realize real-time online detection of blood component purity, cell activity and pollutant residue in the separation process, and synchronously monitors circulation physiological parameters of a blood donor and an equipment operation state at the same time; the closed-loop self-adaptive regulation and control module can dynamically adjust parameters such as the centrifugal rotating speed, the fluid pump speed and the anticoagulant ratio according to real-time monitoring data, and precise closed-loop control over the separation process is achieved. The quality stability of blood single-sampling components can be remarkably improved, meanwhile, the operation risk is greatly reduced, and the method is suitable for clinical blood component single-sampling and preparation scenes.

The invention provides a double-position centrifugal plasma purification system, and belongs to the technical field of plasma purification. Comprising a plasma collection system, a plasma adsorption system and a liquid feedback system, the plasma collection system and the liquid feedback system are both connected with a blood supplier to form a blood closed-loop conveying loop, and the plasma adsorption system is connected with the plasma collection system and the liquid feedback system; the plasma collecting system comprises two centrifugal machines and further comprises a back-flushing cleaning system, and the two centrifugal machines are alternately connected with the plasma collecting system and the back-flushing cleaning system through a first control valve and a second control valve. The centrifugal machine after each round of blood separation is flushed through the backflushing cleaning system, blood residues in a container of the centrifugal machine are avoided, free hemoglobin rising caused by long-time centrifugation of blood components is avoided, and the effect of improving the safety and reliability of the blood purification process is achieved.

To provide a method and a system for achieving a consistent plasma anticoagulant ratio for a plasma product in plasma exchange processing.SOLUTION: There is provided a method for executing plasma exchange using a plasma separation system including a fluid flow circuit, a plasma separator, and a control unit. The method includes inputting a hematocrit value of a donor, setting a desired plasma anticoagulant ratio for a plasma product, calculating an initial ratio of an anticoagulant to whole blood (ACR), and executing separation by the separation system. The system also includes a programmable control unit having a screen for receiving an input from an operator, which is configured to give the initial ACR on the basis of the input from the operator, and activate the system on the basis of the initial ACR.SELECTED DRAWING: Figure 1

A blood component sampling cassette which can be more efficiently manufactured at lower cost as compared to a typical cassette, a blood sampling circuit set, and a blood component sampling system. A blood component sampling cassette (22) includes a cassette main body (23) made of a soft material to which heat sterilization is applicable. The cassette main body (23) is provided with a retransfusion line (44). The retransfusion line (44) is provided with a reservoir (47) configured to temporarily store a blood component to be returned to a blood donor. The reservoir (47) is pressed by a retransfusion pump (49) to discharge the blood component from the reservoir (47).

The invention discloses a HIV (human immunodeficiency virus), HBV (hepatitis B virus), HCV (hepatitis C virus) and TP (total protein) hypersensitive detection kit and detection method based on a digital PCR (polymerase chain reaction) platform. The kit comprises a primer and a probe, the design of the primer and the probe is optimized, and the molecular detection system has higher sensitivity by utilizing high affinity and strong mismatch recognition capability of the LNA probe, so that a single copy can be detected. The method possibly has huge potential in the aspects of large-scale screening and clinical diagnosis of blood donors and epidemiological research of pathogens.

A distributed computing system for managing blood collection procedures in a blood collection facility includes a system server including a memory and a communication interface, the system server configured to store data identifiers for a plurality of different human operators. A plurality of computerized blood collection instruments are configured to collect blood from donors to generate collected products, each blood collection instrument comprising a communication interface configured to transmit data regarding the blood collection instrument to the system server. The system server stores data identifiers for each blood collection instrument. A computer is coupled to the system server and configured to present a dashboard for improving operational performance at and / or across blood collection facilities. The dashboard displays procedure data, data regarding the plurality of different human operators and data tracking each operator's activities or performance on a display.

The utility model relates to the field of medical auxiliary equipment, in particular to a relieving device for plasma collection, which comprises a seat and an air pipe, an air pump is mounted in the seat, a controller is mounted on a handrail of the seat and is in wired connection with the air pump, a fixing plate is arranged on the seat, a fastening sliding hole is formed in the fixing plate, and the air pipe is connected with the air pump. A relieving air bag is slidably connected into the fastening sliding hole, one end of the air pipe is communicated with the air pump, the other end of the air pipe is communicated with the relieving air bag, and an adjusting assembly used for moving the fixing plate back and forth is arranged on the seat. By means of the air pump and the air pipe which are used for conveying air to the relieving air bag, a blood drawing person can adjust the air pressure in the air bag through the controller according to the feeling of the person, so that the appropriate gripping force is achieved, people with different gripping forces can use the relieving air bag to conduct the gripping action, and the applicability of the device is optimized.

The invention relates to the field of data security, and particularly discloses a blood donor personal information security storage and access management method based on cloud computing, which comprises the following steps of: 1, performing full-link protection on the personal information of a blood donor by adopting a three-layer encryption architecture; 2, extracting a gene sequence, combining the gene sequence with the identity identification information, and generating an encryption key through Hash operation; 3, adopting a fusion access control model based on roles and attributes; 4, triggering secondary authentication for the account exceeding the threshold value; 5, calling the identity identification information to carry out biological identification authentication, and accessing the corresponding encrypted information after the biological identification authentication is passed; according to the method, high-risk access is identified by combining historical behaviors and a risk scoring mechanism of a network environment, and threats such as account embezzlement are intercepted through differentiated processing; the uniqueness of biological recognition and a multi-person verification mechanism of family combination authentication solve the problem that traditional passwords are easy to leak, prevent a single person from abusing authority, and realize consideration of security storage and practicability of personal information.

The utility model is suitable for the technical field of whole blood collection and preparation devices, and provides a full-automatic whole blood collection and preparation machine with a matched disposable device, which comprises a full-automatic whole blood collection and preparation machine and a disposable collection and preparation device, the full-automatic whole blood collecting and preparing machine comprises a control system, a pipeline light sensor, a pipeline pressure monitor, a weighing device, a pipeline bubble monitor, a centrifugal machine system, a valve, an air pressure cuff and a peristaltic pump, the disposable collecting and preparing device is provided with a centrifugal cup, a blood bag, a pipeline and the like, and the pipeline comprises a whole blood pipeline for blood matching and the like. According to the full-automatic whole blood collecting and preparing machine with the matched disposable device, through the collecting and preparing method, a certain amount of peripheral venous blood of a blood donor can be collected and mixed with a certain proportion of blood maintenance liquid to form whole blood, meanwhile, the whole blood can be separated into red blood cells, plasma and albuginea, and the separated red blood cells can be used for collecting and preparing the whole blood. The washing red blood cells can be further prepared on the equipment.

The utility model relates to the field of medical instruments, in particular to a blood matching test tube rack for clinical blood transfusion. Comprising a base, a fixing plate, a separation frame, a fixing block, an adjusting lead screw and an identification mechanism. A plurality of first placing holes and two first sliding grooves are formed in the upper side of the base, a fixing plate is arranged on the upper side of the base, a plurality of second placing holes and two second sliding grooves are formed in the upper side of the fixing plate, and the first placing holes and the first sliding grooves of the base correspond to the second placing holes and the second sliding grooves of the fixing plate in a one-to-one mode. The first containing holes and the second containing holes are evenly distributed in three rows and multiple columns, two separation frames are arranged in the second sliding groove of the fixing plate in a sliding mode, the separation frames are connected with the first sliding grooves in a sliding mode, and fixing blocks are arranged on the front sides of the separation frames. The sizes of the blood donor test tube area, the cross blood matching test tube area and the blood acceptor test tube area can be flexibly adjusted through the matching of the separation frame and the adjusting screw rod, so that the test tube rack is suitable for different clinical scene requirements and avoids confusion of test tubes.

A method for collecting plasma includes receiving donor information and demographic information and determining a target volume of plasma to collect based, at least in part, on the received donor information. The method also determines a plasma collection protocol based, at least in part, on the received donor information. The plasma collection protocol has a plurality of collection parameters and a plurality of process parameters. The method may then adjust at least one of the plurality of collection parameters and / or the plurality of process parameters based on the donor information and / or the demographic information. The method also performs a plasma collection procedure according to the determined plasma collection protocol and adjusted collection parameters and / or process parameters. The plasma collection procedure has a plurality of draw cycles and a plurality of return cycles.

The invention provides an SNP (Single Nucleotide Polymorphism) site of an ABO blood group variant, and a B subtype variant blood group identification kit and method, and relates to the technical field of biology. The SNP sites of the ABO blood group variant comprise the 648th site c. 648Cgt from an initiation codon of an ABO gene coding region; g mutation. A substance for detecting the SNP site of the ABO blood group variant can be applied to preparation of a B subtype variant blood group identification method and product, so that the substance can be effectively applied to rapid detection of patients and blood donors, the B subtype variant blood group of an individual can be defined, and potential possible blood transfusion reaction can be prevented in time.

A system for minimizing a residual blood value via a plasma rinseback includes a collection bag, a return reservoir, one or more pumps, and one or more lines. The collection bag is configured to store plasma collected from a donor during a donation process. The return reservoir is configured to collect fluid remaining in the system after the donation process is complete. The one or more pumps are configured to be actuated between an operational state and a nonoperational state during the donation process and the plasma rinseback. The one or more lines are configured to couple the collection bag, the return reservoir, the one or more pumps, and the donor. The system is configured to complete the plasma rinseback to return fluid within the system to the donor after the donation process is complete.

The invention discloses a centrifugal belt type blood cell separation detection system and detection method, and belongs to the technical field of blood cell detection.The method comprises the steps that an initial optimal control track is planned and generated according to a state baseline and physiological indexes of a blood donor; tracking an actual separation trajectory, comparing the actual separation trajectory with the initial trajectory, and quantizing to generate a real-time dynamic deviation vector; when the deviation exceeds a dynamic threshold value, performing causal attribution analysis to generate a deviation attribution weight matrix; performing iterative fine tuning on the control instruction according to an attribution result until convergence, and outputting a closed-loop steady-state control flow field to execute compensation; and finally, evaluating and collecting performance, constructing a digital twinning process resume, and feeding back a function mapping relation of an optimization system. According to the method, a cooperative control strategy integrating prediction planning, real-time tracking, causal attribution, dynamic compensation and learning optimization is adopted, and intelligent detection and control of precision, self-adaption and continuous optimization of the blood cell separation process can be achieved.

The invention discloses an adjustable sampling device for cross blood matching examination, and relates to the technical field of medical instruments, the adjustable sampling device comprises a device main body, the top of the interior of the device main body is rotatably provided with a bidirectional screw rod, and one side of the top of the device main body is fixedly provided with a first servo motor; a transmission gear is fixedly installed at the output end of the first servo motor, a driven gear is fixedly installed on the outer side of the bidirectional lead screw and meshed with the transmission gear, a limiting rod is fixedly installed in the device body and located above the bidirectional lead screw, and two first sliding blocks are installed on the outer side of the bidirectional lead screw in a threaded mode. The device has the beneficial effects that the position of the dropper can be automatically adjusted according to the positions of the placed test tubes filled with serum of a blood supplier and a blood receiver and unused test tubes in the blood cross matching process, then the serum of the blood supplier and the blood receiver is sampled and then dropped into the test tube to be dropped, and the serum of the blood supplier and the blood receiver can be sampled and inspected at the same time; the working efficiency is high.

A method for collecting plasma includes receiving donor information and demographic information and determining a target volume of plasma to collect based, at least in part, on the received donor information. The method also determines a plasma collection protocol based, at least in part, on the received donor information. The plasma collection protocol has a plurality of collection parameters and a plurality of process parameters. The method may then adjust at least one of the plurality of collection parameters and / or the plurality of process parameters based on the donor information and / or the demographic information. The method also performs a plasma collection procedure according to the determined plasma collection protocol and adjusted collection parameters and / or process parameters. The plasma collection procedure has a plurality of draw cycles and a plurality of return cycles.

A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.

The present invention relates to a device for processing blood containers. A device for processing blood containers, comprising: a data storage reader unit (20) adapted to read a blood donor identifier from a data storage of a blood container, and a data processing unit (50) adapted to request blood donor-related information from a database (163) based on the read blood donor identifier, in order to allow correct processing of all relevant information regarding the blood donor and the blood recipient, to correctly match the blood and avoid any serious harm on the blood recipient side.

The invention provides a blood purification treatment system, and belongs to the technical field of medical equipment. Comprising a plasma collection system, a plasma adsorption system and a liquid feedback system which are connected with a blood supplier to form a blood closed-loop conveying loop, the plasma collection system comprises a blood collection tube, the blood collection tube is connected with centrifugal machines through two blood collection branch tubes, and the outlet ends of the two centrifugal machines are jointly connected with a first plasma bag; the two blood collection branch pipes are connected with a blood collection system and connected with a blood collection adsorption system through a first blood collection bag, blood collection pumps are arranged on the two blood collection branch pipes, the blood collection branch pipes are connected with first back-transfusion branch pipes, and the two first back-transfusion branch pipes are combined and then connected with a liquid back-transfusion system. The electric valve assembly is used for controlling only one of the two blood sampling branch pipes to be opened at the same time and controlling the first feedback branch pipe and the blood sampling branch pipe to be opened and closed in opposite states. In the process of pumping blood to one centrifugal machine and centrifugally separating blood plasma on line, red blood cells in the other centrifugal machine are transfused back to the human body, and the effects of continuously keeping blood sampling and liquid transfusing back and improving the blood sampling efficiency are achieved.

The utility model relates to the technical field of intelligent blood sampling, in particular to an intelligent blood sampling robot which comprises a blood sampling device body, a display screen and an authentication unit, the authentication unit is arranged on the blood sampling device body, and blood donors are registered and recognized through the authentication unit; the intelligent blood sampling robot comprises a blood sampling device body, an authentication unit, a blood sampling unit and a blood sampling unit, and the blood sampling unit is arranged on the blood sampling device body. The system integrates the function of a blood sampling scale, double stations work independently, the clamping mechanism can clamp four test tubes at a time, sample reserving tubes are labeled automatically, labels are checked automatically, caps are removed automatically, plugs are broken off automatically, the test tubes are clamped and conveyed to a sample reserving box automatically, samples are reserved in bypass bags automatically, the samples are reserved in the sample reserving tubes automatically, the samples are weighed, the samples are shaken up automatically, blood braids flow back, needle heads are heat-sealed, and the needle heads are twisted off. The needle head is separated and automatically recycled, the catheter is thermally sealed, and the working efficiency is greatly improved through the full-automatic technology.

This application discloses a method, device, medium, and program product for managing plasma donor fatigue recovery, addressing the problem in existing technologies where individual physiological responses of different plasma donors during plasma donation are not considered, leading to fatigue recovery predictions that deviate from individual realities and a lack of targeted intervention timing and content. The method includes: acquiring stressor time-series data and individual digital profiles of plasma donors; characterizing the donor's sensitivity to anticoagulant metabolism and fatigue recovery ability based on the stressor time-series data and individual digital profiles; predicting the plasma donor's fatigue recovery trajectory after plasma donation based on the stressor time-series data and individual digital profiles; determining at least one intervention time point based on the fatigue recovery trajectory, and pushing fatigue recovery guidance information to the plasma donor at the intervention time point.

The utility model discloses an adjustable blood drawing tool, and relates to the technical field of medical instruments. The blood transfusion device comprises a blood storage bottle, a blood transfusion tube is arranged at one end of the blood storage bottle, a blood drawing needle is fixedly installed at the end, away from the blood storage bottle, of the blood transfusion tube, and an adjusting assembly is arranged on the outer wall of the blood transfusion tube and can adjust the flow speed of blood in the blood transfusion tube. Before blood drawing, the blood storage bottle can be pressed, at the moment, the pressure intensity of the internal space of the blood storage bottle is increased, the blood storage bottle can draw blood of a patient out of the body through the blood transfusion tube, meanwhile, the flow speed in the blood transfusion tube is controlled by adjusting the position of the adjusting gear in the adjusting groove, and the adjustable blood drawing flow speed is achieved; the problems that when a blood drawing tool is used, the blood drawing flow velocity cannot be adjusted, if the flow velocity is too slow, the risk that blood is coagulated in a blood collection bag is increased, and consequently a blood sample cannot be used are solved. And blood coagulation not only wastes blood resources, but also possibly causes unnecessary psychological and physiological pressure to blood donors.