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Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties. Whereas the structural properties are largely intrinsic, functional properties and the derived classifications depend to a certain degree on the type of chemical interaction partners on which the function is exerted.
Site-specific antibody conjugation and antibody-drug conjugate as concrete example of site-specific antibody conjugation
To provide a technique for specifically shifting a chemical functional group to a specific site of an antibody.SOLUTION: The application relates to a technique for achieving labelling of a specific site of an antibody with a specific number of chemical functional groups or cargo parts. An antibody product material having high uniformity can be provided according to the application. In addition, an antibody product material in which function of an antibody is not reduced, is also provided according to the application. Namely, an antibody product material in which avidity and half life period are not reduced, can be provided. The application provides a first technique and extremely significant technique for achieving labelling of a specific site of an antibody without a complicated process.SELECTED DRAWING: None
Owner:ABTIS CO LTD
Site-specific antibody conjugation and antibody-drug conjugate as specific embodiment thereof
The present invention relates to technology capable of labeling a certain site of an antibody with a certain number of chemical functional groups or cargo moieties. The present invention may provide an antibody product having high uniformity. The present invention may provide an antibody product whose antibody functions are not degraded. That is, the present invention may provide an antibody product whose antibody binding affinity and half-life are not degraded. The present invention is of great significance as being the first technology allowing site-specific labeling of an antibody without any complicated processes.
Owner:ABTIS CO LTD