The application belongs to but is not limited to the technical field of Blattella germanica prevention and treatment, and discloses a Blattella germanica prevention and treatment method and
system based on
nanoparticle delivery of lethal
gene dsRNA, which comprises the following steps: Blattella germanica lethal
gene full-length
cloning;
plasmid construction and dsRNA expression and purification; and RNAi feeding. The application first confirms an efficient RNAi lethal target point for Blattella germanica, ensures the efficiency of the technical scheme, realizes low-cost and large-scale preparation of an
active ingredient of an RNAi insecticide, breaks through the cost
bottleneck of commercial application, creatively constructs a
nanocomposite delivery system, efficiently overcomes the technical
bottleneck of oral delivery of RNAi, and provides an environment-friendly practical prevention and treatment scheme, and has important application value and prospect.