The application discloses a nano material for targeting and driving
resuscitation of dying cells, and a preparation method and application thereof. The nano material is a nano
platelet vesicle with
phosphatidylserine exposed to the outer layer of the membrane after nanoization and centrifugal treatment. The material is obtained by separating and enriching platelets from
peripheral blood, then nanoizing the platelets, and then inducing the
phosphatidylserine on the
platelet membrane to evert through high-speed
centrifugation. The material is used for preparing a
medicine for promoting
tissue repair, and the
medicine promotes
resuscitation of dying cells by targeting the dying cells and enhancing the membrane repair capacity of the dying cells, so as to promote
tissue repair, including repair of orthopedic,
muscle,
skin,
spinal cord or visceral tissue, especially repair of
diabetic foot,
skin avulsion injury, ischemic
skin flap or
spinal cord injury. The
resuscitation of dying cells is promoted successfully without intervention of
lysis programmed cell death initiation, so that the problems of off-target effect and treatment paradox existing in current mainstream
small molecule inhibitor strategy are effectively solved.