The application discloses a self-adaptable and fixable coagulation monitoring flexible
pressure sensor and a preparation method thereof. The pressure-sensitive layer of the flexible
pressure sensor is a
nanofiber membrane with hundred-
microstructure prepared by an
electrospinning process. The
nanofiber membrane is prepared by mixing
polylactic acid with shape memory as a base material and multi-walled carbon nanotubes as a conductive substance. The preparation method of the flexible
pressure sensor is simple, and the flexible pressure sensor has high sensitivity under small load. The pressure-sensitive layer of the sensor has an initial shape and a temporary shape, and can be transformed between the initial shape and the temporary shape under external stimulation driving. The installation and fixation of the flexible pressure sensor are realized by controlling the deformation process of the sensor. The
nanofiber membrane is spontaneously deformed and inwards shrunk to be attached on a
central venous catheter, so that the fixation is realized. The stability of the flexible pressure sensor is improved, the flexible pressure sensor is adaptively installed at the front end of the
central venous catheter, and the
blood flow pressure in the
venous blood vessel can be monitored in real time.